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Cell signaling is a complex communication process between individual cells and between cells and their environment. It is the basis for development, immunity, tissue repair, and homeostasis. When signaling molecules or ligands bind to an intracellular protein or a cell surface receptor such as a G-protein coupled receptor (GPCR), it triggers the regulation of cytoplasmic activities or transcription. If any cellular information processing or signal transduction pathway is deregulated, diseases such as autoimmunity, cancer, and diabetes can develop. AAT Bioquest offers a complete range of kits and reagents to detect and quantify signaling molecules involved in a variety of essential pathways from reactive oxygen species (ROS) and kinases to second messengers such as calcium and cAMP.