MCLA [2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one, hydrochloride] CAS 128322-44-1

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Physical properties

Molecular weight	291.73
Solvent	DMSO

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12352200

Overview SDS Protocol

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of MCLA [2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one, hydrochloride] *CAS 128322-44-1* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	342.783 µL	1.714 mL	3.428 mL	17.139 mL	34.278 mL
5 mM	68.557 µL	342.783 µL	685.565 µL	3.428 mL	6.856 mL
10 mM	34.278 µL	171.391 µL	342.783 µL	1.714 mL	3.428 mL

Molarity calculator

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Images

Figure 1. Chemical structure for MCLA [2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one, hydrochloride] *CAS 128322-44-1*

References

View all 44 references: Citation Explorer

Development of imidazopyrazinone red-chemiluminescent probes for detecting superoxide anions via a chemiluminescence resonance energy transfer method
Authors: Teranishi K., undefined
Journal: Luminescence. (2006)

Chemiluminescent visualization of superoxide generated by Candida albicans
Authors: Masui S, Majima T, Nakamura K, Ito-Kuwa S, Takeo K, Aoki S.
Journal: Med Mycol (2004): 427

Effect of endocrine disruptor para-nonylphenol on the cell growth and oxygen radical generation in Escherichia coli mutant cells deficient in catalase and superoxide dismutase
Authors: Okai Y, Sato EF, Higashi-Okai K, Inoue M.
Journal: Free Radic Biol Med (2004): 1412

Immunoglobulin G induces microglial superoxide production
Authors: Yoshida T, Tanaka M, Okamoto K.
Journal: Neurol Res (2002): 361

Superoxide production in the islet of Langerhans detected by the MCLA chemiluminescence method
Authors: Sakurai T, Terakawa S.
Journal: Methods Mol Biol (2002): 203

Chemiluminescence of superoxide generated by Candida albicans: differential effects of the superoxide generator paraquat on a wild-type strain and a respiratory mutant
Authors: Aoki S, Ito-Kuwa S, Nakamura K, Nakamura Y, Vidotto V, Takeo K.
Journal: Med Mycol (2002): 13

Mechanism of superoxide anion production by hepatic sinusoidal endothelial cells and Kupffer cells during short-term ethanol perfusion in the rat
Authors: Hasegawa T, Kikuyama M, Sakurai K, Kambayashi Y, Adachi M, Saniabadi AR, Kuwano H, Nakano M.
Journal: Liver (2002): 321

In vivo measurement of superoxide in the cerebral cortex during anoxia-reoxygenation and ischemia-reperfusion
Authors: Yamaguchi K, Uematsu D, Itoh Y, Watanabe S, Fukuuchi Y.
Journal: Keio J Med (2002): 201

Sinusoidal endothelial cell injury by superoxide anion and iron in the Propionibacterium acnes-pretreated and lipopolysaccharide-stimulated rat liver
Authors: Hasegawa T, Nakano M, Hashimoto T, Hiraishi K, Suzuki K, Kuwano H.
Journal: Liver (2001): 415

A HMG-CoA reductase inhibitor possesses a potent anti-atherosclerotic effect other than serum lipid lowering effects--the relevance of endothelial nitric oxide synthase and superoxide anion scavenging action
Authors: Sumi D, Hayashi T, Thakur NK, Jayach and ran M, Asai Y, Kano H, Matsui H, Iguchi A.
Journal: Atherosclerosis (2001): 347