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BAPTA, tetrapotassium salt *CAS 73630-08-7*

BAPTA (1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid) is a water-soluble and cell-impermeable calcium chelator. It has high selectivity to calcium. BAPTA is a calcium-specific aminopolycarboxylic acid. The presence of four carboxylic acid functional groups makes possible the binding of two calcium ions. The extensive flexibility of the carboxylate ligands is critical to the coordination of calcium and other metal ions.

Calculators

Common stock solution preparation

Table 1. Volume of Water needed to reconstitute specific mass of BAPTA, tetrapotassium salt *CAS 73630-08-7* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM159.036 µL795.178 µL1.59 mL7.952 mL15.904 mL
5 mM31.807 µL159.036 µL318.071 µL1.59 mL3.181 mL
10 mM15.904 µL79.518 µL159.036 µL795.178 µL1.59 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

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Citations

View all 7 citations: Citation Explorer
Regulation of Calcium entry by cyclic GMP signaling in Toxoplasma gondii
Authors: Triana, Miryam A Hortua and M{\'a}rquez-Nogueras, Karla M and Fazli, Mojtaba Sedigh and Quinn, Shannon and Moreno, Silvia NJ
Journal: Journal of Biological Chemistry (2024): 105771
Spautin-1 Ameliorates Acute Pancreatitis via Inhibiting Impaired Autophagy and Alleviating Calcium Overload
Authors: Xiao, Juan and Feng, Xueping and Huang, Xiao-Ying and Huang, Zhongshi and Huang, Yanqiang and Li, Chaogan and Li, Genliang and Nong, Song and Wu, Ruoshi and Huang, Yongzhi and others, undefined
Journal: Molecular Medicine (2016): 643
Helicobacter pylori induces IL-1β protein through the inflammasome activation in differentiated macrophagic cells
Authors: Kameoka, Shoichiro and Kameyama, Takeshi and Hayashi, Takaya and Sato, Seiichi and Ohnishi, Naomi and Hayashi, Takeru and Murata-Kamiya, Naoko and Higashi, Hideaki and Hatakeyama, Masanori and Takaoka, Akinori
Journal: Biomedical Research (2016): 21--27
Licochalcone A induces T24 bladder cancer cell apoptosis by increasing intracellular calcium levels
Authors: Yang, Xinhui and Jiang, Jiangtao and Yang, Xinyan and Han, Jichun and Zheng, Qiusheng
Journal: Molecular medicine reports (2016): 911--919
Delayed administration of the nucleic acid analog 2Cl-C. OXT-A attenuates brain damage and enhances functional recovery after ischemic stroke
Authors: Okabe, Naohiko and Nakamura, Emi and Himi, Naoyuki and Narita, Kazuhiko and Tsukamoto, Ikuko and Maruyama, Tokumi and Sakakibara, Norikazu and Nakamura, Takehiro and Itano, Toshifumi and Miyamoto, Osamu
Journal: Brain research (2013): 115--131
Page updated on September 18, 2024

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Physical properties

Molecular weight

628.79

Solvent

Water

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
UNSPSC12352200

CAS

73630-08-7
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