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MEQ [6-Methoxy-N-ethylquinolinium iodide]

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Physical properties
Molecular weight315.15
SolventDMSO
Spectral properties
Excitation (nm)318
Emission (nm)447
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12352200

OverviewpdfSDSpdfProtocol


CAS
34373-76-7
Molecular weight
315.15
Excitation (nm)
318
Emission (nm)
447
A chloride indicator that has the fluorescence dependent of chloride concentration. Its fluorescence is quenched by chloride through collision quenching.

Calculators


Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of MEQ [6-Methoxy-N-ethylquinolinium iodide] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM317.309 µL1.587 mL3.173 mL15.865 mL31.731 mL
5 mM63.462 µL317.309 µL634.618 µL3.173 mL6.346 mL
10 mM31.731 µL158.655 µL317.309 µL1.587 mL3.173 mL

Molarity calculator

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Spectrum


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spectrum

Spectral properties

Excitation (nm)318
Emission (nm)447

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Citations


View all 2 citations: Citation Explorer
BBA-Molecular and Cell Biology of Lipids
Authors: Zakyrjanova, Guzalia F and Gilmutdinov, Amir I and Tsentsevitsky, Andrey N and Petrov, Alexey M
Journal: (2021)
Olesoxime, a cholesterol-like neuroprotectant restrains synaptic vesicle exocytosis in the mice motor nerve terminals: Possible role of VDACs
Authors: Zakyrjanova, Guzalia F and Gilmutdinov, Amir I and Tsentsevitsky, Andrey N and Petrov, Alexey M
Journal: Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids (2020): 158739

References


View all 24 references: Citation Explorer
Chloride/bicarbonate exchanger SLC26A7 is localized in endosomes in medullary collecting duct cells and is targeted to the basolateral membrane in hypertonicity and potassium depletion
Authors: Xu J, Worrell RT, Li HC, Barone SL, Petrovic S, Amlal H, Soleimani M.
Journal: J Am Soc Nephrol (2006): 956
Shift of intracellular chloride concentration in ganglion and amacrine cells of developing mouse retina
Authors: Zhang LL, Pathak HR, Coulter DA, Freed MA, Vardi N.
Journal: J Neurophysiol (2006): 2404
Chloride-sensitive MEQ fluorescence in chick embryo motoneurons following manipulations of chloride and during spontaneous network activity
Authors: Chub N, Mentis GZ, O'Donovan M J.
Journal: J Neurophysiol (2006): 323
Halide fluxes in epithelial cells measured with an automated cell plate reader
Authors: Mahlangu DA, Dix JA.
Journal: Anal Biochem (2004): 28
Chloride equilibrium potential in salamander cones
Authors: Thoreson WB, Bryson EJ.
Journal: BMC Neurosci (2004): 53
Reciprocal interactions between calcium and chloride in rod photoreceptors
Authors: Thoreson WB, Bryson EJ, Rabl K.
Journal: J Neurophysiol (2003): 1747
Propofol inhibits volume-sensitive chloride channels in human coronary artery smooth muscle cells
Authors: Masuda T, Tomiyama Y, Kitahata H, Kuroda Y, Oshita S.
Journal: Anesth Analg (2003): 657
Modulation of the GABA(A)-gated chloride channel by reactive oxygen species
Authors: Sah R, Galeffi F, Ahrens R, Jordan G, Schwartz-Bloom RD.
Journal: J Neurochem (2002): 383
Optical imaging reveals cation--Cl(-) cotransporter-mediated transient rapid decrease in intracellular Cl(-) concentration induced by oxygen--glucose deprivation in rat neocortical slices
Authors: Yamada Y, Fukuda A, Tanaka M, Shimano Y, Nishino H, Muramatsu K, Togari H, Wada Y.
Journal: Neurosci Res (2001): 269
Effects of lithium on the pharmacokinetics of valproate in rats
Authors: Yoshioka H, Ida S, Yokota M, Nishimoto A, Shibata S, Sugawara A, Takiguchi Y.
Journal: J Pharm Pharmacol (2000): 297