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MQAE [N-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide]

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Physical properties
Molecular weight326.19
SolventDMSO
Spectral properties
Excitation (nm)319
Emission (nm)462
Storage, safety and handling
Certificate of OriginDownload PDF
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12352200

OverviewpdfSDSpdfProtocol


CAS
162558-52-3
Molecular weight
326.19
Excitation (nm)
319
Emission (nm)
462
A chloride indicator that has the fluorescence dependent of chloride concentration. Its fluorescence is quenched by chloride through collision quenching.

Calculators


Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of MQAE [N-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM306.57 µL1.533 mL3.066 mL15.328 mL30.657 mL
5 mM61.314 µL306.57 µL613.14 µL3.066 mL6.131 mL
10 mM30.657 µL153.285 µL306.57 µL1.533 mL3.066 mL

Molarity calculator

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Spectrum


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spectrum

Spectral properties

Excitation (nm)319
Emission (nm)462

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Citations


View all 1 citations: Citation Explorer
Lotus Leaf Alkaloid Extract Displays Sedative--Hypnotic and Anxiolytic Effects through GABAA Receptor
Authors: Yan, Ming-Zhu and Chang, Qi and Zhong, Yu and Xiao, Bing-Xin and Feng, Li and Cao, Fang-Rui and Pan, Rei-Le and Zhang, Ze-Sheng and Liao, Yong-Hong and Liu, Xin-Min
Journal: Journal of agricultural and food chemistry (2015): 9277--9285

References


View all 27 references: Citation Explorer
Chloride and bicarbonate have similar affinities to the intestinal anion exchanger DRA (down regulated in adenoma)
Authors: Lamprecht G, Schaefer J, Dietz K, Gregor M.
Journal: Pflugers Arch (2006): 307
Reversal effect of haloperidol on doxorubicin resistance and chloride channel inhibition in erythroleukemic cell K562/Dox
Authors: Zhou JH, Wu DZ.
Journal: Zhonghua Zhong Liu Za Zhi (2005): 81
On membrane motor activity and chloride flux in the outer hair cell: lessons learned from the environmental toxin tributyltin
Authors: Song L, Seeger A, Santos-Sacchi J.
Journal: Biophys J (2005): 2350
Measurement of halide efflux from cultured and primary airway epithelial cells using fluorescence indicators
Authors: Munkonge F, Alton EW, Andersson C, Davidson H, Dragomir A, Edelman A, Farley R, Hjelte L, McLachlan G, Stern M, Roomans GM.
Journal: J Cyst Fibros (2004): 171
Cell volume response to hyposmotic shock and elevated cAMP in bovine trabecular meshwork cells
Authors: Srinivas SP, Maertens C, Goon LH, Goon L, Satpathy M, Yue BY, Droogmans G, Nilius B.
Journal: Exp Eye Res (2004): 15
Expression and regulation of the Na+-K+-2Cl- cotransporter NKCC1 in the normal and CFTR-deficient murine colon
Authors: Bachmann O, Wuchner K, Rossmann H, Leipziger J, Osikowska B, Colledge WH, Ratcliff R, Evans MJ, Gregor M, Seidler U.
Journal: J Physiol (2003): 525
Activation of CFTR by genistein in human airway epithelial cell lines
Authors: Andersson C, Servetnyk Z, Roomans GM.
Journal: Biochem Biophys Res Commun (2003): 518
Modulation of intracellular Cl- homeostasis by lectin-stimulation in Jurkat T lymphocytes
Authors: Lai ZF, Chen YZ, Nishi K.
Journal: Eur J Pharmacol (2003): 1
Determination of chloride efflux by X-ray microanalysis versus MQAE-fluorescence
Authors: Andersson C, Roomans GM.
Journal: Microsc Res Tech (2002): 531
S-Nitrosoglutathione induces functional DeltaF508-CFTR in airway epithelial cells
Authors: Andersson C, Gaston B, Roomans GM.
Journal: Biochem Biophys Res Commun (2002): 552