MM 1-43 [N-(3-Triethylammoniumpropyl)-4-(4-(dibutylamino)styryl)pyridinium dibromide] *CAS#: 149838-22-2*
Ordering information
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Additional ordering information
Telephone | 1-800-990-8053 |
Fax | 1-800-609-2943 |
sales@aatbio.com | |
International | See distributors |
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Shipping | Standard overnight for United States, inquire for international |
Physical properties
Molecular weight | 611.54 |
Solvent | Water |
Spectral properties
Excitation (nm) | 473 |
Emission (nm) | 579 |
Storage, safety and handling
H-phrase | H303, H313, H333 |
Hazard symbol | XN |
Intended use | Research Use Only (RUO) |
R-phrase | R20, R21, R22 |
Storage | Freeze (< -15 °C); Minimize light exposure |
UNSPSC | 12352200 |
Overview | SDSProtocol |
See also: Cell/Cytoplasmic Membrane Potential Activity & Analysis, Membrane Potential and Channels, Neurodegeneration & Amyloid Staining
CAS 149838-22-2 | Molecular weight 611.54 | Excitation (nm) 473 | Emission (nm) 579 |
MM 1-43 is the abbreviation of our Membrane Marker 1-43, chemically called N-(3-triethylammoniumpropyl)-4-(4-(dibutylamino)styryl)pyridinium dibromide. MM 1-43 is chemically the same molecule of FM 1-43. In literature this membrane marker is also called "FM 1-43" (FM® is the trademark of Molecular Probes). It is a water-soluble membrane probe that belongs to the styryl dye family. It is widely used in cell biology and neurobiology since it has minimal toxicity to cells. MM 1-43 is virtually non-fluorescent in aqueous medium and strongly fluorescent upon binding to membrane. It is efficiently excited with standard fluorescein optical filters, and exhibits an intense fluorescent signal when associated with the plasma membrane. MM 1-43 has frequently been used to quantify exocytosis in neurons. Fluorescence imaging using MM 1-43 and related styryl dyes has provided invaluable insights into presynaptic function of synapses in culture preparations.
Calculators
Common stock solution preparation
Table 1. Volume of Water needed to reconstitute specific mass of MM 1-43 [N-(3-Triethylammoniumpropyl)-4-(4-(dibutylamino)styryl)pyridinium dibromide] *CAS#: 149838-22-2* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.
0.1 mg | 0.5 mg | 1 mg | 5 mg | 10 mg | |
1 mM | 163.522 µL | 817.608 µL | 1.635 mL | 8.176 mL | 16.352 mL |
5 mM | 32.704 µL | 163.522 µL | 327.043 µL | 1.635 mL | 3.27 mL |
10 mM | 16.352 µL | 81.761 µL | 163.522 µL | 817.608 µL | 1.635 mL |
Molarity calculator
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References
View all 27 references: Citation Explorer
Palytoxin-induced effects on partial reactions of the Na,K-ATPase
Authors: Harmel N, Apell HJ.
Journal: J Gen Physiol (2006): 103
Authors: Harmel N, Apell HJ.
Journal: J Gen Physiol (2006): 103
Electrogenic partial reactions of the gastric H,K-ATPase
Authors: Diller A, Vagin O, Sachs G, Apell HJ.
Journal: Biophys J (2005): 3348
Authors: Diller A, Vagin O, Sachs G, Apell HJ.
Journal: Biophys J (2005): 3348
Effective gating charge of ion channels induced by toxin syringomycin E in lipid bilayers
Authors: Schagina LV, Gurnev PA, Takemoto JY, Malev VV.
Journal: Bioelectrochemistry (2003): 21
Authors: Schagina LV, Gurnev PA, Takemoto JY, Malev VV.
Journal: Bioelectrochemistry (2003): 21
Effect of dipole modifiers on the kinetics of sensitized photoinactivation of gramicidin channels in bilayer lipid membranes
Authors: Antonenko YN, Rokitskaya TI, Kotova EA.
Journal: Membr Cell Biol (1999): 111
Authors: Antonenko YN, Rokitskaya TI, Kotova EA.
Journal: Membr Cell Biol (1999): 111
Hofmeister effects of anions on the kinetics of partial reactions of the Na+,K+-ATPase
Authors: Ganea C, Babes A, Lupfert C, Grell E, Fendler K, Clarke RJ.
Journal: Biophys J (1999): 267
Authors: Ganea C, Babes A, Lupfert C, Grell E, Fendler K, Clarke RJ.
Journal: Biophys J (1999): 267
Influence of anions and cations on the dipole potential of phosphatidylcholine vesicles: a basis for the Hofmeister effect
Authors: Clarke RJ, Lupfert C.
Journal: Biophys J (1999): 2614
Authors: Clarke RJ, Lupfert C.
Journal: Biophys J (1999): 2614
Electrogenic partial reactions of the SR-Ca-ATPase investigated by a fluorescence method
Authors: Butscher C, Roudna M, Apell H.
Journal: J Membr Biol (1999): 169
Authors: Butscher C, Roudna M, Apell H.
Journal: J Membr Biol (1999): 169
Effect of gramicidin A on the dipole potential of phospholipid membranes
Authors: Shapovalov VL, Kotova EA, Rokitskaya TI, Antonenko YN.
Journal: Biophys J (1999): 299
Authors: Shapovalov VL, Kotova EA, Rokitskaya TI, Antonenko YN.
Journal: Biophys J (1999): 299
Cable properties of dendrites in hippocampal neurons of the rat mapped by a voltage-sensitive dye
Authors: Meyer E, Muller CO, Fromherz P.
Journal: Eur J Neurosci (1997): 778
Authors: Meyer E, Muller CO, Fromherz P.
Journal: Eur J Neurosci (1997): 778
Effect of the dipole potential of a bilayer lipid membrane on gramicidin channel dissociation kinetics
Authors: Rokitskaya TI, Antonenko YN, Kotova EA.
Journal: Biophys J (1997): 850
Authors: Rokitskaya TI, Antonenko YN, Kotova EA.
Journal: Biophys J (1997): 850
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