logo
AAT Bioquest

BSB [(trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene]

Product Image
Product Image
Gallery Image 1
Ordering information
Price
Catalog Number
Unit Size
Quantity
Add to cart
Additional ordering information
Telephone1-800-990-8053
Fax1-800-609-2943
Emailsales@aatbio.com
InternationalSee distributors
Bulk requestInquire
Custom sizeInquire
ShippingStandard overnight for United States, inquire for international
Request quotation
Physical properties
Molecular weight481.29
SolventDMSO
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12352200

OverviewpdfSDSpdfProtocol


Molecular weight
481.29
BSB is a cell-permeable fluorescent probe that specifically binds to and labels intracellular beta-amyloid aggregates both in vitro (Ki = 400 nM) and in vivo. It is useful as an antemortem diagnostic tool for animal models of Alzheimer's disease.

Calculators


Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of BSB [(trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM207.775 µL1.039 mL2.078 mL10.389 mL20.777 mL
5 mM41.555 µL207.775 µL415.55 µL2.078 mL4.155 mL
10 mM20.777 µL103.887 µL207.775 µL1.039 mL2.078 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)Molecular weightVolume (Calculate)Concentration (Calculate)Moles
/=x=

Images


References


View all 50 references: Citation Explorer
Focus on Molecules: Rod cGMP Phosphodiesterase Type 6
Authors: Ionita MA, Pittler SJ.
Journal: Exp Eye Res (2007): 1
Inhibition of cGMP-phosphodiesterase-5 by biflavones of Ginkgo biloba
Authors: Dell'Agli M, Galli GV, Bosisio E.
Journal: Planta Med (2006): 468
Effect of icariin on cyclic GMP levels and on the mRNA expression of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in penile cavernosum
Authors: Jiang Z, Hu B, Wang J, Tang Q, Tan Y, Xiang J, Liu J.
Journal: J Huazhong Univ Sci Technolog Med Sci (2006): 460
Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway
Authors: Mongillo M, Tocchetti CG, Terrin A, Liss and ron V, Cheung YF, Dostmann WR, Pozzan T, Kass DA, Paolocci N, Houslay MD, Zaccolo M.
Journal: Circ Res (2006): 226
Ca(2+)/calmodulin-dependent cyclic nucleotide phosphodiesterase in cGMP metabolism in rabbit parotid acinar cells
Authors: Sairenji N, Satoh K, Sugiya H.
Journal: Biomed Res (2006): 37
The N terminus of GTP gamma S-activated transducin alpha-subunit interacts with the C terminus of the cGMP phosphodiesterase gamma-subunit
Authors: Grant JE, Guo LW, Vestling MM, Martemyanov KA, Arshavsky VY, Ruoho AE.
Journal: J Biol Chem (2006): 6194
Confirmation of tyrosine 698 in beta subunit of cGMP phosphodiesterase in patients with retinitis pigmentosa and population of the west of Mexico
Authors: Nunez-Gutierrez IC, Garcia-Cruz D, Fragoso-Herrera R, Medina-Lozano C.
Journal: Rev Invest Clin (2006): 359
cGMP stimulates renin secretion in vivo by inhibiting phosphodiesterase-3
Authors: Beierwaltes WH., undefined
Journal: Am J Physiol Renal Physiol (2006): F1376
Phosphodiesterase type 5 siRNA increases cGMP in the smooth muscle cells of human corpus cavernosum
Authors: Chen GQ, Bai WJ, Wang XF, Liu SJ, He PY, Hou SK.
Journal: Zhonghua Nan Ke Xue (2006): 979
GAP-independent termination of photoreceptor light response by excess gamma subunit of the cGMP-phosphodiesterase
Authors: Tsang SH, Woodruff ML, Chen CK, Yamashita CY, Cilluffo MC, Rao AL, Farber DB, Fain GL.
Journal: J Neurosci (2006): 4472