logo
AAT Bioquest

AMC [7-Amino-4-methylcoumarin] *CAS 26093-31-2*

Product Image
Product Image
Gallery Image 1
Ordering information
Price
Catalog Number
Unit Size
Quantity
Add to cart
Additional ordering information
Telephone1-800-990-8053
Fax1-800-609-2943
Emailsales@aatbio.com
InternationalSee distributors
Bulk requestInquire
Custom sizeInquire
ShippingStandard overnight for United States, inquire for international
Request quotation
Physical properties
Molecular weight175.19
SolventDMSO
Spectral properties
Excitation (nm)341
Emission (nm)441
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12171501

OverviewpdfSDSpdfProtocol


See also: Coumarins
CAS
26093-31-2
Molecular weight
175.19
Excitation (nm)
341
Emission (nm)
441
This compound is the precursor for a variety of AMC enzyme substrates. It is also used as a calibration standard for AMC-based enzyme substrates. Fluorogenic AMC substrates are widely used for measuring a variety of protease activities.

Calculators


Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of AMC [7-Amino-4-methylcoumarin] *CAS 26093-31-2* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM570.809 µL2.854 mL5.708 mL28.54 mL57.081 mL
5 mM114.162 µL570.809 µL1.142 mL5.708 mL11.416 mL
10 mM57.081 µL285.404 µL570.809 µL2.854 mL5.708 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)Molecular weightVolume (Calculate)Concentration (Calculate)Moles
/=x=

Spectrum


Open in Advanced Spectrum Viewer
spectrum

Spectral properties

Excitation (nm)341
Emission (nm)441

Images


Citations


View all 3 citations: Citation Explorer
MXene-sensitized electrochemiluminescence sensor for thrombin activity detection and inhibitor screening
Authors: Deng, Zijie and Tan, Xueping and Guo, Dongnan and Zhang, Jing and Xu, Dan and Hou, Xiaofang and Wang, Sicen and Zhang, Junbo and Wei, Fen and Zhang, Dongdong
Journal: Microchimica Acta (2023): 328
Reduced hepatic bradykinin degradation accounts for cold-induced BAT thermogenesis and WAT browning in male mice
Authors: Xiao, Fei and Jiang, Haizhou and Li, Zi and Jiang, Xiaoxue and Chen, Shanghai and Niu, Yuguo and Yin, Hanrui and Shu, Yousheng and Peng, Bo and Lu, Wei and others,
Journal: Nature Communications (2023): 2523
Modulation of CD4&amp;plus; T-cell activation by CD95 co-stimulation
Authors: Paulsen, Maren and Valentin, Signe and Mathew, Biny and Adam-Klages, Sabine and Bertsch, Uwe and Lavrik, Inna and Krammer, Peter H and Kabelitz, Dieter and Janssen, Ottmar
Journal: Cell Death &amp; Differentiation (2011): 619--631

References


View all 142 references: Citation Explorer
Peripheral proteasome and caspase activity in Parkinson disease and Alzheimer disease
Authors: Bl, undefined and ini F, Sinforiani E, Pacchetti C, Samuele A, Bazzini E, Zangaglia R, Nappi G, Martignoni E.
Journal: Neurology (2006): 529
Active cathepsins B, H, K, L and S in human inflammatory bronchoalveolar lavage fluids
Authors: Serveau-Avesque C, Martino MF, Herve-Grepinet V, Hazouard E, Gauthier F, Diot E, Lalmanach G.
Journal: Biol Cell (2006): 15
A role for Angiotensin-converting enzyme in the characterization, enrichment, and proliferation potential of adult murine pituitary colony-forming cells
Authors: Lepore DA, Jokubaitis VJ, Simmons PJ, Roeszler KN, Rossi R, Bauer K, Thomas PQ.
Journal: Stem Cells (2006): 2382
Paenidase, a Novel D-Aspartyl Endopeptidase from Paenibacillus sp. B38: Purification and Substrate Specificity
Authors: Takahashi S, Ogasawara H, Hiwatashi K, Hori K, Hata K, Tachibana T, Itoh Y, Sugiyama T.
Journal: J Biochem (Tokyo) (2006): 197
Recovery of free oligosaccharides from derivatives labeled by reductive amination
Authors: Suzuki S, Fujimori T, Yodoshi M.
Journal: Anal Biochem (2006): 94
Characterization and microbial utilization of dissolved organic carbon in groundwater contaminated with chlorophenols
Authors: Langwaldt JH, Munster U, Puhakka JA.
Journal: Chemosphere (2005): 983
Discovery of a sulfated tetrapeptide that binds to vascular endothelial growth factor
Authors: Maynard HD, Hubbell JA.
Journal: Acta Biomater (2005): 451
Mechanism of human SIRT1 activation by resveratrol
Authors: Borra MT, Smith BC, Denu JM.
Journal: J Biol Chem (2005): 17187
Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers
Authors: Herter S, Piper DE, Aaron W, Gabriele T, Cutler G, Cao P, Bhatt AS, Choe Y, Craik CS, Walker N, Meininger D, Hoey T, Austin RJ.
Journal: Biochem J (2005): 125
delta-(D -alpha-Aminoadipoyl)-cleaving amidase of Ochrobactrum anthropi
Authors: Patett F, Fischer L.
Journal: Biotechnol Lett (2005): 1915