Name: Biotin-beta-Amyloid (1-42) [beta-Amyloid (1-42), Biotin-Labeled]
Brand: AAT Bioquest
SKU: 81110
Price: 128 USD
Availability: InStock

Biotin-beta-Amyloid (1-42)

beta-Amyloid (1-42), Biotin-Labeled

Biotin-beta-Amyloid (1-42) is a biotin-labeled peptide used extensively in neuroscience research, particularly in studies related to Alzheimer’s disease.

Sequence Length: 42 amino acids from the N-terminal region of the full Aβ peptide
Biomarker: It is used as a highly accurate diagnostic marker for AD pathology
High Quality: Multimode of analytical tools are used to ensure the material quality and reduce batch-to-batch variation

Chemical structure of Biotin-beta-Amyloid (1-42).

Datasheet

SDS

COA

Catalog	Size	Price	Quantity
81110	100 ug	Price

Overview

Biotin-beta-Amyloid (1-42) is a biotin-labeled peptide used extensively in neuroscience research, particularly in studies related to Alzheimer’s disease. Biotin tag is conjugated to the N-termini of beta-Amyloid (1-42) peptide with sequence: Biotin-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH (DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA). AAT Bioquest’s Biotin-beta-Amyloid (1-42) material is thoroughly analyzed to ensure its quality by HPLC, electrophoresis and cell functional analysis. Beta-Amyloid (1-42) is a peptide fragment derived from the amyloid precursor protein (APP). It is the primary component of amyloid plaques found in the brains of individuals with Alzheimer’s disease. Beta-Amyloid (1-42) is used in neurotoxicity, neuroinflammation and drug screening studies. Aβ(1-42) aggregates into fibrils and oligomers that are neurotoxic.

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of Biotin-beta-Amyloid (1-42) [beta-Amyloid (1-42), Biotin-Labeled] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	18.446 µL	92.231 µL	184.461 µL	922.307 µL	1.845 mL
5 mM	3.689 µL	18.446 µL	36.892 µL	184.461 µL	368.923 µL
10 mM	1.845 µL	9.223 µL	18.446 µL	92.231 µL	184.461 µL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	5421.19 g/mol	=	mL	x	mM	=	mmol

References

View all 50 references: Citation Explorer

Advances and future trends in the detection of beta-amyloid: A comprehensive review.

Authors:

Ganguly, Atri and Babu, Srivalliputtur Sarath and Ghosh, Sumanta and Velyutham, Ravichandiran and Kapusetti, Govinda

Journal:

Medical engineering & physics (2025): 104269

PU.1 dictates β-amyloid-induced TREM2 expression upregulation in microglia in a transgenic model of Alzheimer's disease.

Authors:

Wei, Zhen and Pan, Xiaodong and Cui, Xiaoli and Zhang, Jing and Dai, Xiaoman and Zeng, Yuqi and Chen, Xiaochun

Journal:

Frontiers in aging neuroscience (2025): 1537388

Fluorescent aptasensor based on target-induced hairpin conformation switch coupled with nicking enzyme-assisted signal amplification for detection of beta-amyloid oligomers in cerebrospinal fluid.

Authors:

Chuang, Wan-Chen and Chen, Chun-Hsien and Duh, Tsai-Hui and Chen, Yen-Ling

Journal:

Mikrochimica acta (2025): 70

Silica-coated gold nanorods conjugated with CRANAD to improve the detection of soluble β-amyloid species via a surface-enhanced fluorescence effect.

Authors:

Oyarzún, María Paz and Cabrera, Pablo and Parra-Muñoz, Nicole and López-Monsalves, Valentina and Riveros, Ana Luisa and Celis, Freddy and Gimeno-Muñoz, Raquel and González-Campo, Arántzazu and Aliaga-Alcalde, Núria and Soler, Mónica and Kogan, Marcelo J

Journal:

Colloids and surfaces. B, Biointerfaces (2025): 114660

Alterations of endocannabinoid signaling and microglia reactivity in the retinas of AD-like mice precede the onset of hippocampal β-amyloid plaques.

Authors:

Tisi, Annamaria and Scipioni, Lucia and Carozza, Giulia and Di Re, Lucia and Cimino, Giacomo and Di Meo, Camilla and Palaniappan, Sakthimala and Valle, Francesco Della and Fanti, Federico and Giacovazzo, Giacomo and Compagnone, Dario and Maccarone, Rita and Oddi, Sergio and Maccarrone, Mauro

Journal:

Journal of neurochemistry (2025): e16256

Physical properties

Molecular weight	5421.19
Solvent	DMSO

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure

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Page updated on June 23, 2026