GMP-Fluorescein conjugate calibrator
Ordering information
Price | |
Catalog Number | |
Unit Size | |
Quantity |
Additional ordering information
Telephone | 1-800-990-8053 |
Fax | 1-800-609-2943 |
sales@aatbio.com | |
International | See distributors |
Bulk request | Inquire |
Custom size | Inquire |
Shipping | Standard overnight for United States, inquire for international |
Physical properties
Molecular weight | ~800 |
Solvent | DMSO |
Spectral properties
Absorbance (nm) | 487 |
Correction Factor (260 nm) | 0.32 |
Correction Factor (280 nm) | 0.35 |
Extinction coefficient (cm -1 M -1) | 800001 |
Excitation (nm) | 498 |
Emission (nm) | 517 |
Quantum yield | 0.79001, 0.952 |
Storage, safety and handling
H-phrase | H303, H313, H333 |
Hazard symbol | XN |
Intended use | Research Use Only (RUO) |
R-phrase | R20, R21, R22 |
Storage | Freeze (< -15 °C); Minimize light exposure |
UNSPSC | 12352200 |
Overview | SDSProtocol |
See also: Fluoresceins
Molecular weight ~800 | Absorbance (nm) 487 | Correction Factor (260 nm) 0.32 | Correction Factor (280 nm) 0.35 | Extinction coefficient (cm -1 M -1) 800001 | Excitation (nm) 498 | Emission (nm) 517 | Quantum yield 0.79001, 0.952 |
GMP-Fluorescein conjugate calibrator is desigend to use with our green fluorescent FAM-cGMP PDE V substrate (#Cat: 13604), a cGMP derivative that is a specific substrate for phosphodiesterase (PDE) V. This GMP-Fluorescein conjugate calibrator is the hydrolyzed product of FAM-cGMP PDE V substrate by PDE V. It is used to calibrate the hydrolysis rate of FAM-cGMP PDE V substrate by PDE V.
Spectrum
Open in Advanced Spectrum Viewer
Spectral properties
Absorbance (nm) | 487 |
Correction Factor (260 nm) | 0.32 |
Correction Factor (280 nm) | 0.35 |
Extinction coefficient (cm -1 M -1) | 800001 |
Excitation (nm) | 498 |
Emission (nm) | 517 |
Quantum yield | 0.79001, 0.952 |
Product Family
Name | Excitation (nm) | Emission (nm) | Extinction coefficient (cm -1 M -1) | Quantum yield | Correction Factor (260 nm) | Correction Factor (280 nm) |
AMP-Fluorescein conjugate calibrator | 498 | 517 | 800001 | 0.79001, 0.952 | 0.32 | 0.35 |
References
View all 34 references: Citation Explorer
Oxidative stress employs phosphatidyl inositol 3-kinase and ERK signalling pathways to activate cAMP phosphodiesterase-4D3 (PDE4D3) through multi-site phosphorylation at Ser239 and Ser579
Authors: Hill EV, Sheppard CL, Cheung YF, Gall I, Krause E, Houslay MD.
Journal: Cell Signal (2006): 2056
Authors: Hill EV, Sheppard CL, Cheung YF, Gall I, Krause E, Houslay MD.
Journal: Cell Signal (2006): 2056
Leptin interferes with adrenocorticotropin/3',5'-cyclic adenosine monophosphate (cAMP) signaling, possibly through a Janus kinase 2-phosphatidylinositol 3-kinase/Akt-phosphodiesterase 3-cAMP pathway, to down-regulate cholesterol side-chain cleavage cytochr
Authors: Hsu HT, Chang YC, Chiu YN, Liu CL, Chang KJ, Guo IC.
Journal: J Clin Endocrinol Metab (2006): 2761
Authors: Hsu HT, Chang YC, Chiu YN, Liu CL, Chang KJ, Guo IC.
Journal: J Clin Endocrinol Metab (2006): 2761
Helix-1 of the cAMP-specific phosphodiesterase PDE4A1 regulates its phospholipase-D-dependent redistribution in response to release of Ca2+
Authors: Huston E, Gall I, Houslay TM, Houslay MD.
Journal: J Cell Sci (2006): 3799
Authors: Huston E, Gall I, Houslay TM, Houslay MD.
Journal: J Cell Sci (2006): 3799
TcPDE4, a novel membrane-associated cAMP-specific phosphodiesterase from Trypanosoma cruzi
Authors: Alonso GD, Schoijet AC, Torres HN, Flawia MM.
Journal: Mol Biochem Parasitol (2006): 40
Authors: Alonso GD, Schoijet AC, Torres HN, Flawia MM.
Journal: Mol Biochem Parasitol (2006): 40
Intracellular targeting of phosphodiesterase-4 underpins compartmentalized cAMP signaling
Authors: Lynch MJ, Hill EV, Houslay MD.
Journal: Curr Top Dev Biol (2006): 225
Authors: Lynch MJ, Hill EV, Houslay MD.
Journal: Curr Top Dev Biol (2006): 225
Compartmentalization of cAMP-Dependent Signaling by Phosphodiesterase-4D Is Involved in the Regulation of Vasopressin-Mediated Water Reabsorption in Renal Principal Cells
Authors: Stefan E, Wiesner B, Baillie GS, Mollajew R, Henn V, Lorenz D, Furkert J, Santamaria K, Nedvetsky P, Hundsrucker C, Beyermann M, Krause E, Pohl P, Gall I, Macintyre AN, Bachmann S, Houslay MD, Rosenthal W, Klussmann E.
Journal: J Am Soc Nephrol. (2006)
Authors: Stefan E, Wiesner B, Baillie GS, Mollajew R, Henn V, Lorenz D, Furkert J, Santamaria K, Nedvetsky P, Hundsrucker C, Beyermann M, Krause E, Pohl P, Gall I, Macintyre AN, Bachmann S, Houslay MD, Rosenthal W, Klussmann E.
Journal: J Am Soc Nephrol. (2006)
PDE7A1, a cAMP-specific phosphodiesterase, inhibits cAMP-dependent protein kinase by a direct interaction with C
Authors: Han P, Sonati P, Rubin C, Michaeli T.
Journal: J Biol Chem (2006): 15050
Authors: Han P, Sonati P, Rubin C, Michaeli T.
Journal: J Biol Chem (2006): 15050
Importance of cAMP-response element-binding protein in regulation of expression of the murine cyclic nucleotide phosphodiesterase 3B (Pde3b) gene in differentiating 3T3-L1 preadipocytes
Authors: Liu H, Tang JR, Choi YH, Napolitano M, Hockman S, Taira M, Degerman E, Manganiello VC.
Journal: J Biol Chem (2006): 21096
Authors: Liu H, Tang JR, Choi YH, Napolitano M, Hockman S, Taira M, Degerman E, Manganiello VC.
Journal: J Biol Chem (2006): 21096
DdPDE4, a novel cAMP-specific phosphodiesterase at the surface of dictyostelium cells
Authors: Bader S, Kortholt A, Snippe H, Van Haastert PJ.
Journal: J Biol Chem (2006): 20018
Authors: Bader S, Kortholt A, Snippe H, Van Haastert PJ.
Journal: J Biol Chem (2006): 20018
Phosphodiesterase-5 Gln817 is critical for cGMP, vardenafil, or sildenafil affinity: its orientation impacts cGMP but not cAMP affinity
Authors: Zoraghi R, Corbin JD, Francis SH.
Journal: J Biol Chem (2006): 5553
Authors: Zoraghi R, Corbin JD, Francis SH.
Journal: J Biol Chem (2006): 5553
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