TSQ [N-(6-Methoxy-8-quinolyl)-p-toluenesulfonamide]

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Physical properties

Molecular weight	328.38
Solvent	DMSO

Spectral properties

Excitation (nm)	355
Emission (nm)	499

Storage, safety and handling

Certificate of Origin	Download PDF
H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12352200

Overview SDS Protocol

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of TSQ [N-(6-Methoxy-8-quinolyl)-p-toluenesulfonamide] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	304.525 µL	1.523 mL	3.045 mL	15.226 mL	30.453 mL
5 mM	60.905 µL	304.525 µL	609.05 µL	3.045 mL	6.091 mL
10 mM	30.453 µL	152.263 µL	304.525 µL	1.523 mL	3.045 mL

Molarity calculator

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Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
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Spectrum

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Spectral properties

Excitation (nm)	355
Emission (nm)	499

Images

Figure 1. Chemical structure for TSQ [N-(6-Methoxy-8-quinolyl)-p-toluenesulfonamide]

Citations

View all 5 citations: Citation Explorer

Iron free zinc oxide nanoparticles with ion-leaking properties disrupt intracellular ROS and iron homeostasis to induce ferroptosis
Authors: Zhang, Changping and Liu, Zixuan and Zhang, Yuhao and Ma, Liang and Song, Erqun and Song, Yang
Journal: Cell Death \& Disease (2020): 1--15

Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation
Authors: Liu, Zixuan and Lv, Xuying and Xu, Lei and Liu, Xuting and Zhu, Xiangyu and Song, Erqun and Song, Yang
Journal: Particle and fibre toxicology (2020): 1--17

The role of nitric oxide synthase in an early phase Cd-induced acute cytotoxicity in MCF-7 cells
Authors: Zhong, Lingying and Wang, Lumei and Xu, Lurong and Liu, Qunlu and Jiang, Linlei and Zhi, Yuee and Lu, Wei and Zhou, Pei
Journal: Biological trace element research (2015): 130--138

The role of NOS-mediated ROS accumulation in an early phase Cu-induced acute cytotoxicity in MCF-7 cells
Authors: Zhong, Lingying and Wang, Lumei and Xu, Lurong and Liu, Qunlu and Jiang, Linlei and Zhi, Yuee and Lu, Wei and Zhou, Pei
Journal: Biometals (2015): 113--122

References

View all 36 references: Citation Explorer

Neurotoxic zinc translocation into hippocampal neurons is inhibited by hypothermia and is aggravated by hyperthermia after traumatic brain injury in rats
Authors: Suh SW, Frederickson CJ, Danscher G.
Journal: J Cereb Blood Flow Metab (2006): 161

In vivo measurement of presynaptic Zn2+ release during forebrain ischemia in rats
Authors: Kitamura Y, Iida Y, Abe J, Mifune M, Kasuya F, Ohta M, Igarashi K, Saito Y, Saji H.
Journal: Biol Pharm Bull (2006): 821

Zinc release contributes to hypoglycemia-induced neuronal death
Authors: Suh SW, Garnier P, Aoyama K, Chen Y, Swanson RA.
Journal: Neurobiol Dis (2004): 538

Method for identifying neuronal cells suffering zinc toxicity by use of a novel fluorescent sensor
Authors: Frederickson CJ, Burdette SC, Sensi SL, Weiss JH, Yin HZ, Balaji RV, Truong-Tran AQ, Bedell E, Prough DS, Lippard SJ.
Journal: J Neurosci Methods (2004): 79

Histochemical and histofluorescence tracing of chelatable zinc in the developing mouse
Authors: Nitzan YB, Sekler I, Silverman WF.
Journal: J Histochem Cytochem (2004): 529

Abundance of zinc ions in synaptic terminals of mocha mutant mice: zinc transporter 3 immunohistochemistry and zinc sulphide autometallography
Authors: Stoltenberg M, Nejsum LN, Larsen A, Danscher G.
Journal: J Mol Histol (2004): 141

Clioquinol effects on tissue chelatable zinc in mice
Authors: Nitzan YB, Sekler I, Frederickson CJ, Coulter DA, Balaji RV, Liang SL, Margulis A, Hershfinkel M, Silverman WF.
Journal: J Mol Med (Berl) (2003): 637

Development and characterization of simulant pancreatic islets
Authors: Maghasi AT, Schlueter KT, Halsall HB, Heineman WR, Rodriguez Rilo HL.
Journal: Anal Biochem (2003): 38

Intracellular zinc fluxes associated with apoptosis in growth plate chondrocytes
Authors: Sauer GR, Smith DM, Cahalane M, Wu LN, Wuthier RE.
Journal: J Cell Biochem (2003): 954

Expression of P2X6, a purinergic receptor subunit, is affected by dietary zinc deficiency in rat hippocampus
Authors: Chu Y, Mouat MF, Coffield JA, Orl and o R, Grider A.
Journal: Biol Trace Elem Res (2003): 77