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IL-21R-STAT3 signalling initiates a differentiation program in uterine tissue-resident NK cells to support pregnancy
Authors: Han, Mengwei and Hu, Luni and Wu, Di and Zhang, Yime and Li, Peng and Zhao, Xingyu and Zeng, Yanyu and Ren, Guanqun and Hou, Zhiyuan and Pang, Yanli and others,
Journal: Nature Communications (2023): 7109

The Dietary Flavonoid Fisetin Causes Cell Cycle Arrest, Caspase-Dependent Apoptosis, and Enhanced Cytotoxicity of Chemotherapeutic Drugs in Triple-Negative Breast Cancer Cells
Authors: Smith, M. L., Murphy, K., Doucette, C. D., Greenshields, A. L., Hoskin, D. W.
Journal: J Cell Biochem (2016): 1913-25

Contribution of membrane progesterone receptor alpha to the induction of progesterone-mediated apoptosis associated with mitochondrial membrane disruption and caspase cascade activation in Jurkat cell lines
Authors: Kon, A., Yuan, B., Hanazawa, T., Kikuchi, H., Sato, M., Furutani, R., Takagi, N., Toyoda, H.
Journal: Oncol Rep (2013): 1965-70

TNF induces caspase-dependent inflammation in renal endothelial cells through a Rho- and myosin light chain kinase-dependent mechanism
Authors: Wu, X., Guo, R., Chen, P., Wang, Q., Cunningham, P. N.
Journal: Am J Physiol Renal Physiol (2009): F316-26

Pan-caspase inhibition suppresses polyethylene particle-induced osteolysis
Authors: L, undefined and graeber, S., Jaeckel, S., Loer, F., Wedemeyer, C., Hilken, G., Canbay, A., Totsch, M., von Knoch, M.
Journal: Apoptosis (2009): 173-81

Inhibition of Caspase-Like Activities Prevents the Appearance of Reactive Oxygen Species and Dark-Induced Apoptosis in the Unicellular Chlorophyte Dunaliella Tertiolecta(1)
Authors: Segovia, M., Berges, J. A.
Journal: J Phycol (2009): 1116-26

Silvestrol, a potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7
Authors: Kim, S., Hwang, B. Y., Su, B. N., Chai, H., Mi, Q., Kinghorn, A. D., Wild, R., Swanson, S. M.
Journal: Anticancer Res (2007): 2175-83

Leptin induces interleukin-1beta release from rat microglial cells through a caspase 1 independent mechanism
Authors: Pinteaux, E., Inoue, W., Schmidt, L., Molina-Holgado, F., Rothwell, N. J., Luheshi, G. N.
Journal: J Neurochem (2007): 826-33

Lipopolysaccharide accelerates caspase-independent but cathepsin B-dependent death of human lung epithelial cells
Authors: Tang, P. S., Tsang, M. E., Lodyga, M., Bai, X. H., Miller, A., Han, B., Liu, M.
Journal: J Cell Physiol (2006): 457-67

Selective caspase activation may contribute to neurological dysfunction after experimental spinal cord trauma
Authors: Knoblach, S. M., Huang, X., VanGelderen, J., Calva-Cerqueira, D., Faden, A. I.
Journal: J Neurosci Res (2005): 369-80

C-terminal region of Bfl-1 induces cell death that accompanies caspase activation when fused with GFP
Authors: Yang, W. S., Ko, J. K., Park, S. O., Choi, H. Y., Kim, Y. N., Kim, C. W.
Journal: J Cell Biochem (2005): 1234-47

Inhibitors directed towards caspase-1 and -3 are less effective than pan caspase inhibition in preventing renal proximal tubular cell apoptosis
Authors: Yang, B., El Nahas, A. M., Fisher, M., Wagner, B., Huang, L., Storie, I., Barnett, D., Barratt, J., Smith, A. C., Johnson, T. S.
Journal: Nephron Exp Nephrol (2004): e39-51

Caspase-3 activation in systemic anaplastic large-cell lymphoma
Authors: Drakos, E., Rassidakis, G. Z., Lai, R., Herling, M., O'Connor, S. L., Schmitt-Graeff, A., McDonnell, T. J., Medeiros, L. J.
Journal: Mod Pathol (2004): 109-16

Differential effects of caspase inhibitors on the renal dysfunction and injury caused by ischemia-reperfusion of the rat kidney
Authors: Chatterjee, P. K., Todorovic, Z., Sivarajah, A., Mota-Filipe, H., Brown, P. A., Stewart, K. N., Cuzzocrea, S., Thiemermann, C.
Journal: Eur J Pharmacol (2004): 173-83

Generation of retinal ganglion cells is modulated by caspase-dependent programmed cell death
Authors: Mayordomo, R., Valenciano, A. I., de la Rosa, E. J., Hallbook, F.
Journal: Eur J Neurosci (2003): 1744-50

Effects of caspase inhibition on the progression of experimental glomerulonephritis
Authors: Yang, B., Johnson, T. S., Haylor, J. L., Wagner, B., Watson, P. F., El Kossi, M. M., Furness, P. N., El Nahas, A. M.
Journal: Kidney Int (2003): 2050-64

Caspase-dependent and -independent apoptosis of mast cells induced by withdrawal of IL-3 is prevented by Toll-like receptor 4-mediated lipopolysaccharide stimulation
Authors: Yoshikawa, H., Tasaka, K.
Journal: Eur J Immunol (2003): 2149-59

Magnoliae flos induces apoptosis of RBL-2H3 cells via mitochondria and caspase
Authors: Kim, G. C., Lee, S. G., Park, B. S., Kim, J. Y., Song, Y. S., Kim, J. M., Yoo, K. S., Huh, G. Y., Jeong, M. H., Lim, Y. J., Kim, H. M., Yoo, Y. H.
Journal: Int Arch Allergy Immunol (2003): 101-10

High molecular weight DNA fragments are processed by caspase sensitive or caspase independent pathways in cultures of cerebellar granule neurons
Authors: Slagsvold, H. H., Rossel and , C. M., Jacobs, C., Khuong, E., Kristoffersen, N., Gaarder, M., Fallgren, A. B., Huitfeldt, H. S., Paulsen, R. E.
Journal: Brain Res (2003): 111-21

Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties
Authors: Caserta, T. M., Smith, A. N., Gultice, A. D., Reedy, M. A., Brown, T. L.
Journal: Apoptosis (2003): 345-52

Tumor necrosis factor-related apoptosis-inducing ligand induces caspase-dependent interleukin-8 expression and apoptosis in human astroglioma cells
Authors: Choi, C., Kutsch, O., Park, J., Zhou, T., Seol, D. W., Benveniste, E. N.
Journal: Mol Cell Biol (2002): 724-36

Caspase activation in equine influenza virus induced apoptotic cell death
Authors: Lin, C., Holl and , R. E., Jr., Donofrio, J. C., McCoy, M. H., Tudor, L. R., Chambers, T. M.
Journal: Vet Microbiol (2002): 357-65

Caspase inhibitors promote the survival of avulsed spinal motoneurons in neonatal rats
Authors: Chan, Y. M., Wu, W., Yip, H. K., So, K. F., Oppenheim, R. W.
Journal: Neuroreport (2001): 541-5

Caspase-independent commitment phase to apoptosis in activated blood T lymphocytes: reversibility at low apoptotic insult
Authors: Dumont, C., Durrbach, A., Bidere, N., Rouleau, M., Kroemer, G., Bernard, G., Hirsch, F., Charpentier, B., Susin, S. A., Senik, A.
Journal: Blood (2000): 1030-8

Involvement of caspase 3- and 8-like proteases in ceramide-induced apoptosis of cardiomyocytes
Authors: Wang, J., Zhen, L., Klug, M. G., Wood, D., Wu, X., Mizrahi, J.
Journal: J Card Fail (2000): 243-9

Transforming growth factor beta induces caspase 3-independent cleavage of alphaII-spectrin (alpha-fodrin) coincident with apoptosis
Authors: Brown, T. L., Patil, S., Cianci, C. D., Morrow, J. S., Howe, P. H.
Journal: J Biol Chem (1999): 23256-62

Inhibition of caspase activity in retinal cell apoptosis induced by various stimuli in vitro
Authors: Tezel, G., Wax, M. B.
Journal: Invest Ophthalmol Vis Sci (1999): 2660-7

Caspase-independent cell death induced by anti-CD2 or staurosporine in activated human peripheral T lymphocytes
Authors: Deas, O., Dumont, C., MacFarlane, M., Rouleau, M., Hebib, C., Harper, F., Hirsch, F., Charpentier, B., Cohen, G. M., Senik, A.
Journal: J Immunol (1998): 3375-83

Caspase inhibitors prevent cisplatin-induced apoptosis of auditory sensory cells
Authors: Liu, W., Staecker, H., Stupak, H., Malgrange, B., Lefebvre, P., Van De Water, T. R.
Journal: Neuroreport (1998): 2609-14

Caspase-3/CPP32-like activity is not sufficient to mediate apoptosis in an IL-2 dependent T cell line
Authors: Vasilakos, J. P., Lynch, T., Ghayur, T., Giegel, D. A., Santoro, M., Shivers, B. D.
Journal: Apoptosis (1997): 289-303

Suppression of human T cell proliferation by the caspase inhibitors, z-VAD-FMK and z-IETD-FMK is independent of their caspase inhibition properties
Authors: Lawrence CP, Chow SC.
Journal: Toxicol Appl Pharmacol. (2012)

Inhibition of elicitation of allergic contact dermatitis by topical use of Z-VAD-FMK, a broad caspase inhibitor: experiment in mice
Authors: Li YY, Yan CL.
Journal: Zhonghua Yi Xue Za Zhi (2012): 1992

Structure of human caspase-6 in complex with Z-VAD-FMK: New peptide binding mode observed for the non-canonical caspase conformation
Authors: Muller I, Lamers MB, Ritchie AJ, Dominguez C, Munoz-Sanjuan I, Kiselyov A.
Journal: Bioorg Med Chem Lett (2011): 5244

Intracochlear perfusion of leupeptin and z-VAD-FMK: influence of antiapoptotic agents on gunshot-induced hearing loss
Authors: Abaamrane L, Raffin F, Schmerber S, Sendowski I.
Journal: Eur Arch Otorhinolaryngol (2011): 987

Plasmodium falciparum metacaspase PfMCA-1 triggers a z-VAD-fmk inhibitable protease to promote cell death
Authors: Meslin B, Beavogui AH, Fasel N, Picot S.
Journal: PLoS One (2011): e23867

Pretreatment with pancaspase inhibitor (Z-VAD-FMK) delays but does not prevent intraperitoneal heat-killed group B Streptococcus-induced preterm delivery in a pregnant mouse model
Authors: Equils O, Moffatt-Blue C, Ishikawa TO, Simmons CF, Ilievski V, Hirsch E.
Journal: Infect Dis Obstet Gynecol (2009): 749432

Attenuation of allergic contact dermatitis by Z-VAD-FMK, a broad caspase inhibitor: experiment with mice
Authors: Li YY, Yan CL, Xu W.
Journal: Zhonghua Yi Xue Za Zhi (2008): 3153

Bodipy-VAD-Fmk, a useful tool to study yeast peptide N-glycanase activity
Authors: Witte MD, Descals CV, de Lavoir SV, Florea BI, van der Marel GA, Overkleeft HS.
Journal: Org Biomol Chem (2007): 3690

Effects of caspase inhibitors (z-VAD-fmk, z-VDVAD-fmk) on Nile Red fluorescence pattern in 7-ketocholesterol-treated cells: investigation by flow cytometry and spectral imaging microscopy
Authors: Vejux A, Lizard G, Tourneur Y, Riedinger JM, Frouin F, Kahn E.
Journal: Cytometry A (2007): 550

Caspase inhibitor Z-VAD-FMK enhances the freeze-thaw survival rate of human embryonic stem cells
Authors: Heng BC, Clement MV, Cao T.
Journal: Biosci Rep (2007): 257

z-VAD-fmk-induced non-apoptotic cell death of macrophages: possibilities and limitations for atherosclerotic plaque stabilization
Authors: Martinet W, Schrijvers DM, Herman AG, De Meyer GR.
Journal: Autophagy (2006): 312

z-VAD-fmk inhibits peptide:N-glycanase and may result in ER stress
Authors: Misaghi S, Korbel GA, Kessler B, Spooner E, Ploegh HL.
Journal: Cell Death Differ (2006): 163

z-VAD-fmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species
Authors: Cowburn AS, White JF, Deighton J, Walmsley SR, Chilvers ER.
Journal: Blood (2005): 2970

The augmentation of TNFalpha-induced cell death in murine L929 fibrosarcoma by the pan-caspase inhibitor Z-VAD-fmk through pre-mitochondrial and MAPK-dependent pathways
Authors: Huang J, Wu L, Tashiro S, Onodera S, Ikejima T.
Journal: Acta Med Okayama (2005): 253

Short-term culture with the caspase inhibitor z-VAD.fmk reduces beta cell apoptosis in transplanted islets and improves the metabolic outcome of the graft
Authors: Montolio M, Tellez N, Biarnes M, Soler J, Montanya E.
Journal: Cell Transplant (2005): 59

Rescue of defective branching nephrogenesis in renal-coloboma syndrome by the caspase inhibitor, Z-VAD-fmk
Authors: Clark P, Dziarmaga A, Eccles M, Goodyer P.
Journal: J Am Soc Nephrol (2004): 299

5-fluorouracil-induced oligodendrocyte death and inhibitory effect of cycloheximide, Trolox, and Z-VAD-FMK in murine cortical culture
Authors: Cho KH, Choi SM, Kim BC, Lee SH, Park MS, Kim MK, Kim JK.
Journal: Cancer (2004): 1484

Caspase inhibitor Z-VAD-FMK potentiates heat shock-induced apoptosis and HSP70 synthesis in macrophages
Authors: Malyshev IY, Pshennikova MG, Shimkovich MV, Malysheva EV.
Journal: Bull Exp Biol Med (2004): 230

Inhibition of apoptosis by Z-VAD-fmk in SMN-depleted S2 cells
Authors: Ilangovan R, Marshall WL, Hua Y, Zhou J.
Journal: J Biol Chem (2003): 30993

Effects of BAPTA-AM, Forskolin, DSF and Z.VAD.fmk on PDT-induced apoptosis and m-THPC phototoxicity on B16 cells
Authors: Thibaut S, Bourre L, Hernot D, Rousset N, Lajat Y, Patrice T.
Journal: Apoptosis (2002): 99

Sensitivity of photoreceptor-derived cell line (661W) to baculoviral p35, Z-VAD.FMK, and Fas-associated death domain
Authors: Tuohy G, Millington-Ward S, Kenna PF, Humphries P, Farrar GJ.
Journal: Invest Ophthalmol Vis Sci (2002): 3583

The history of Z-VAD-FMK, a tool for understanding the significance of caspase inhibition
Authors: Van Noorden CJ., undefined
Journal: Acta Histochem (2001): 241

Caspase inhibitor z-VAD-FMK inhibits keratocyte apoptosis, but promotes keratocyte necrosis, after corneal epithelial scrape
Authors: Kim WJ, Mohan RR, Wilson SE.
Journal: Exp Eye Res (2000): 225

Baculovirus p35 and Z-VAD-fmk inhibit thapsigargin-induced apoptosis of breast cancer cells
Authors: Qi XM, He H, Zhong H, Distelhorst CW.
Journal: Oncogene (1997): 1207

Camptothecin-induced apoptosis in p53-null human leukemia HL60 cells and their isolated nuclei: effects of the protease inhibitors Z-VAD-fmk and dichloroisocoumarin suggest an involvement of both caspases and serine proteases
Authors: Shimizu T, Pommier Y.
Journal: Leukemia (1997): 1238

Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32
Authors: Slee EA, Zhu H, Chow SC, MacFarlane M, Nicholson DW, Cohen GM.
Journal: Biochem J (1996): 21