Citation Explorer

Sphingomyelin synthase 1 supports two steps of rubella virus life cycle
Authors: Yagi, Mayuko and Hama, Minami and Ichii, Sayaka and Nakashima, Yurie and Kanbayashi, Daiki and Kurata, Takako and Yusa, Kosuke and Komano, Jun
Journal: iScience (2023)

Polyphyllin D “Punctures” Hypertrophic Lysosomes to Reverse Drug Resistance of Hepatocellular Carcinoma by Targeting Acid Sphingomyelinase
Authors: Wang, Yang and Chen, Yan-Yan and Gao, Gui-Bin and Zheng, Yang-Han and Yu, Nan-Nan and Ouyang, Lan and Gao, Xuejuan and Li, Nan and Wen, Shi-Yuan and Huang, Shangjia and others,
Journal: Molecular Therapy (2023)

Sphingomyelin synthase activity affects TRIF-dependent signaling of Toll-like receptor 4 in cells stimulated with lipopolysaccharide
Authors: Prymas, Kamila and Swiatkowska, Anna and Traczyk, Gabriela and Ziemlińska, Ewelina and Dziewulska, Anna and Ciesielska, Anna and Kwiatkowska, Katarzyna
Journal: Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids (2019): 158549

Doxepin mitigates noise induced neuronal damage in primary auditory cortex of mice via suppression of acid sphingomyelinase/ceramide pathway
Authors: Su, Yu-Ting and Meng, Xing-Xing and Zhang, Xi and Guo, Yi-Bin and Zhang, Hai-Jun and Cheng, Yao-Ping and Xie, Xiao-Ping and Chang, Yao-Ming and Bao, Jun-Xiang
Journal: The Anatomical Record (2017)

Riccardin DN induces lysosomal membrane permeabilization by inhibiting acid sphingomyelinase and interfering with sphingomyelin metabolism in vivo
Authors: Li, Lin and Niu, Huanmin and Sun, Bin and Xiao, Yanan and Li, Wei and Yuan, Huiqing and Lou, Hongxiang
Journal: Toxicology and Applied Pharmacology (2016): 175--184

New Aspects of Silibinin Stereoisomers and their 3-O-galloyl Derivatives on Cytotoxicity and Ceramide Metabolism in Hep G2 hepatocarcinoma Cell Line
Authors: Mashhadi Akbar Boojar, Mahdi and Ejtemaei Mehr, Shahram and Hassanipour, Mahsa and Mashhadi Akbar Boojar, Masoud and Dehpour, Ahmad Reza
Journal: Iranian Journal of Pharmaceutical Research (2016): 421--433

Mitochondrial respiration controls lysosomal function during inflammatory T cell responses
Authors: Baixauli, Francesc and Acín-Pérez, Rebeca and Villarroya-Beltrí, Carolina and Mazzeo, Carla and Nunez-Andrade, Norman and Gab, undefined and é-Rodriguez, Enrique and Ledesma, Maria Dolores and Blázquez, Alberto and Martin, Miguel Angel and Falcón-Pérez, Juan Manuel and others, undefined
Journal: Cell metabolism (2015): 485--498

The ATP-binding cassette transporter-2 (ABCA2) regulates esterification of plasma membrane cholesterol by modulation of sphingolipid metabolism
Authors: Davis, Warren
Journal: Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids (2014): 168--179

A high-throughput sphingomyelinase assay using natural substrate
Authors: Xu, Miao and Liu, Ke and Southall, Noel and Marugan, Juan J and Remaley, Alan T and Zheng, Wei
Journal: Analytical and bioanalytical chemistry (2012): 407--414

Phospholipase C and sphingomyelinase activities of the Clostridium perfringens alpha-toxin
Authors: Urbina P, Flores-Diaz M, Alape-Giron A, Alonso A, Goni FM.
Journal: Chem Phys Lipids (2009): 51

Sphingomyelinase-induced ceramide production stimulate calcium-independent JNK and PP2A activation following cerebral ischemia
Authors: Tian HP, Qiu TZ, Zhao J, Li LX, Guo J.
Journal: Brain Inj (2009): 1073

SMase II, a new sphingomyelinase D from Loxosceles laeta venom gland: molecular cloning, expression, function and structural analysis
Authors: de Santi Ferrara GI, Fern and es-Pedrosa Mde F, Junqueira-de-Azevedo Ide L, Goncalves-de-Andrade RM, Portaro FC, Manzoni-de-Almeida D, Murakami MT, Arni RK, van den Berg CW, Ho PL, Tambourgi DV.
Journal: Toxicon (2009): 743

Neutral sphingomyelinase-induced ceramide accumulation by oxidative stress during carbon tetrachloride intoxication
Authors: Ichi I, Kamikawa C, Nakagawa T, Kobayashi K, Kataoka R, Nagata E, Kitamura Y, Nakazaki C, Matsura T, Kojo S.
Journal: Toxicology (2009): 33

Purification, characterization, and gene cloning of sphingomyelinase C from Streptomyces griseocarneus NBRC13471
Authors: Sugimori D., undefined
Journal: J Biosci Bioeng (2009): 293

Transcriptional regulation of neutral sphingomyelinase 2 gene expression of a human breast cancer cell line, MCF-7, induced by the anti-cancer drug, daunorubicin
Authors: Ito H, Murakami M, Furuhata A, Gao S, Yoshida K, Sobue S, Hagiwara K, Takagi A, Kojima T, Suzuki M, Banno Y, Tanaka K, Tamiya-Koizumi K, Kyogashima M, Nozawa Y, Murate T.
Journal: Biochim Biophys Acta (2009): 681

ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition, increased susceptibility for sphingomyelinase, and increased binding to biglycan
Authors: Hiukka A, Stahlman M, Pettersson C, Levin M, Adiels M, Teneberg S, Leinonen ES, Hulten LM, Wiklund O, Oresic M, Olofsson SO, Taskinen MR, Ekroos K, Boren J.
Journal: Diabetes (2009): 2018

Structure and function of sphingomyelinase
Authors: Oda M., undefined
Journal: Yakugaku Zasshi (2009): 1233

Expression of alkaline sphingomyelinase in yeast cells and anti-inflammatory effects of the expressed enzyme in a rat colitis model
Authors: Andersson D, Kotarsky K, Wu J, Agace W, Duan RD.
Journal: Dig Dis Sci (2009): 1440

A complex extracellular sphingomyelinase of Pseudomonas aeruginosa inhibits angiogenesis by selective cytotoxicity to endothelial cells
Authors: Vasil ML, Stonehouse MJ, Vasil AI, Wadsworth SJ, Goldfine H, Bolcome RE, 3rd, Chan J.
Journal: PLoS Pathog (2009): e1000420

Alterations of myelin-specific proteins and sphingolipids characterize the brains of acid sphingomyelinase-deficient mice, an animal model of Niemann-Pick disease type A
Authors: Buccinna B, Piccinini M, Prinetti A, Sc and roglio F, Prioni S, Valsecchi M, Votta B, Grifoni S, Lupino E, Ramondetti C, Schuchman EH, Giordana MT, Sonnino S, Rinaudo MT.
Journal: J Neurochem (2009): 105

A novel mitochondrial sphingomyelinase in zebrafish cells
Authors: Yabu T, Shimuzu A, Yamashita M.
Journal: J Biol Chem (2009): 20349

A novel sphingomyelinase-like enzyme in Ixodes scapularis tick saliva drives host CD4 T cells to express IL-4
Authors: Alarcon-Chaidez FJ, Boppana VD, Hagymasi AT, Adler AJ, Wikel SK.
Journal: Parasite Immunol (2009): 210

Integrin-associated Lyn kinase promotes cell survival by suppressing acid sphingomyelinase activity
Authors: Chudakova DA, Zeidan YH, Wheeler BW, Yu J, Novgorodov SA, Kindy MS, Hannun YA, Gudz TI.
Journal: J Biol Chem (2008): 28806

Identification of Mg2+ -dependent neutral sphingomyelinase 1 as a mediator of heat stress-induced ceramide generation and apoptosis
Authors: Yabu T, Imamura S, Yamashita M, Okazaki T.
Journal: J Biol Chem (2008): 29971

Acid sphingomyelinase involvement in tumor necrosis factor alpha-regulated vascular and steroid disruption during luteolysis in vivo
Authors: Henkes LE, Sullivan BT, Lynch MP, Kolesnick R, Arsenault D, Puder M, Davis JS, Rueda BR.
Journal: Proc Natl Acad Sci U S A (2008): 7670

Anomalous surface distribution of glycosyl phosphatidyl inositol-anchored proteins in neurons lacking acid sphingomyelinase
Authors: Galvan C, Camoletto PG, Cristofani F, Van Veldhoven PP, Ledesma MD.
Journal: Mol Biol Cell (2008): 509

Lysosomal targeting and trafficking of acid sphingomyelinase to lipid raft platforms in coronary endothelial cells
Authors: Jin S, Yi F, Zhang F, Poklis JL, Li PL.
Journal: Arterioscler Thromb Vasc Biol (2008): 2056

Sphingomyelinase deficiency (Niemann-Pick disease) in a Hereford calf
Authors: Saunders GK, Wenger DA.
Journal: Vet Pathol (2008): 201

Regulation of neutral sphingomyelinase-2 (nSMase2) by tumor necrosis factor-alpha involves protein kinase C-delta in lung epithelial cells
Authors: Clarke CJ, Guthrie JM, Hannun YA.
Journal: Mol Pharmacol (2008): 1022

Effect of sphingomyelinase treatment on ligand binding activity of human serotonin1A receptors
Authors: Jafurulla M, Pucadyil TJ, Chattopadhyay A.
Journal: Biochim Biophys Acta (2008): 2022

Effect of sphingomyelinase-mediated generation of ceramide on aggregation of low-density lipoprotein
Authors: Walters MJ, Wrenn SP.
Journal: Langmuir (2008): 9642

Acid sphingomyelinase overexpression enhances the antineoplastic effects of irradiation in vitro and in vivo
Authors: Smith EL, Schuchman EH.
Journal: Mol Ther (2008): 1565

Increase of skin-ceramide levels in aged subjects following a short-term topical application of bacterial sphingomyelinase from Streptococcus thermophilus
Authors: Di Marzio L, Cinque B, Cupelli F, De Simone C, Cifone MG, Giuliani M.
Journal: Int J Immunopathol Pharmacol (2008): 137

Acid sphingomyelinase promotes lipoprotein retention within early atheromata and accelerates lesion progression
Authors: Devlin CM, Leventhal AR, Kuriakose G, Schuchman EH, Williams KJ, Tabas I.
Journal: Arterioscler Thromb Vasc Biol (2008): 1723

A new anti-loxoscelic serum produced against recombinant sphingomyelinase D: results of preclinical trials
Authors: de Almeida DM, Fern and es-Pedrosa Mde F, de Andrade RM, Marcelino JR, Gondo-Higashi H, de Azevedo Ide L, Ho PL, van den Berg C, Tambourgi DV.
Journal: Am J Trop Med Hyg (2008): 463

Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias
Authors: Kim WJ, Okimoto RA, Purton LE, Goodwin M, Haserlat SM, Dayyani F, Sweetser DA, McClatchey AI, Bernard OA, Look AT, Bell DW, Scadden DT, Haber DA.
Journal: Blood (2008): 4716

Acid sphingomyelinase-deficient Niemann-Pick disease: novel findings in a Greek child
Authors: Fotoulaki M, Schuchman EH, Simonaro CM, Augoustides-Savvopoulou P, Michelakakis H, Panagopoulou P, Varlamis G, Nousia-Arvanitakis S.
Journal: J Inherit Metab Dis (2007): 986

Exogenous sphingomyelinase causes impaired intestinal epithelial barrier function
Authors: Bock J, Liebisch G, Schweimer J, Schmitz G, Rogler G.
Journal: World J Gastroenterol (2007): 5217

Intraparenchymal injections of acid sphingomyelinase results in regional correction of lysosomal storage pathology in the Niemann-Pick A mouse
Authors: Yang WW, Dodge JC, Passini MA, Taksir TV, Griffiths D, Schuchman EH, Cheng SH, Shihabuddin LS.
Journal: Exp Neurol (2007): 258

Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide
Authors: Lang PA, Schenck M, Nicolay JP, Becker JU, Kempe DS, Lupescu A, Koka S, Eisele K, Klarl BA, Rubben H, Schmid KW, Mann K, Hildenbr and S, Hefter H, Huber SM, Wieder T, Erhardt A, Haussinger D, Gulbins E, Lang F.
Journal: Nat Med (2007): 164

Highly variable neural involvement in sphingomyelinase-deficient Niemann-Pick disease caused by an ancestral Gypsy mutation
Authors: Mihaylova V, Hantke J, Sinigerska I, Cherninkova S, Raicheva M, Bouwer S, Tincheva R, Khuyomdziev D, Bertranpetit J, Ch and ler D, Angelicheva D, Kremensky I, Seeman P, Tournev I, Kalaydjieva L.
Journal: Brain (2007): 1050

Secretory sphingomyelinase is upregulated in chronic heart failure: a second messenger system of immune activation relates to body composition, muscular functional capacity, and peripheral blood flow
Authors: Doehner W, Bunck AC, Rauchhaus M, von Haehling S, Brunkhorst FM, Cicoira M, Tschope C, Ponikowski P, Claus RA, Anker SD.
Journal: Eur Heart J (2007): 821

Analysis of membrane topology of neutral sphingomyelinase 2
Authors: Tani M, Hannun YA.
Journal: FEBS Lett (2007): 1323

Association analysis of sphingomyelinase 2 polymorphisms for the extrinsic type of atopic dermatitis in Koreans
Authors: Kim HT, Lee JY, Han BG, Kimm K, Oh B, Shin HD, Namkung JH, Kim E, Park T, Yang JM.
Journal: J Dermatol Sci (2007): 143

Relationship of tumor necrosis factor alpha expression with activation of sphingomyelinase and lipid peroxidation after removal of cholestatic factor
Authors: Dudnik LB, Tsiupko AN, Shupik MA, Akhaladze GG, Gal'perin EI, Platonova LV, Pantaz EA, Iasnetsov VV, Smirnov LD, Alesenko AV.
Journal: Izv Akad Nauk Ser Biol (2007): 8-Jan

Curcumin decreases acid sphingomyelinase activity in colon cancer Caco-2 cells
Authors: Cheng Y, Kozubek A, Ohlsson L, Sternby B, Duan RD.
Journal: Planta Med (2007): 725

Constitutive acid sphingomyelinase enhances early and late macrophage killing of Salmonella enterica serovar Typhimurium
Authors: McCollister BD, Myers JT, Jones-Carson J, Voelker DR, Vazquez-Torres A.
Journal: Infect Immun (2007): 5346

Identification of aberrant forms of alkaline sphingomyelinase (NPP7) associated with human liver tumorigenesis
Authors: Cheng Y, Wu J, Hertervig E, Lindgren S, Duan D, Nilsson A, Duan RD.
Journal: Br J Cancer (2007): 1441

Acid sphingomyelinase deficiency increases susceptibility to fatal alphavirus encephalomyelitis
Authors: Ng CG, Griffin DE.
Journal: J Virol (2006): 10989

TRAIL activates acid sphingomyelinase via a redox mechanism and releases ceramide to trigger apoptosis
Authors: Dumitru CA, Gulbins E.
Journal: Oncogene (2006): 5612

Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A
Authors: Smith AR, Visioli F, Frei B, Hagen TM.
Journal: Aging Cell (2006): 391

Exogenous sphingomyelinase increases collagen and sulphated glycosaminoglycan production by primary articular chondrocytes: an in vitro study
Authors: Gilbert SJ, Blain EJ, Jones P, Duance VC, Mason DJ.
Journal: Arthritis Res Ther (2006): R89

Down-regulation of neutral sphingomyelinase in androgen-dependent smooth muscle
Authors: Durham JP, Mawhinney MG.
Journal: J Surg Res (2006): 136

Role of matrix metalloproteinases in HaCaT keratinocytes apoptosis induced by loxosceles venom sphingomyelinase D
Authors: Paixao-Cavalcante D, van den Berg CW, de Freitas Fern and es-Pedrosa M, Goncalves de Andrade RM, Tambourgi DV.
Journal: J Invest Dermatol (2006): 61

Identification of novel biomarkers for Niemann-Pick disease using gene expression analysis of acid sphingomyelinase knockout mice
Authors: Dhami R, Passini MA, Schuchman EH.
Journal: Mol Ther (2006): 556

Niemann-Pick type C disease: novel NPC1 mutations and characterization of the concomitant acid sphingomyelinase deficiency
Authors: Tamura H, Takahashi T, Ban N, Torisu H, Ninomiya H, Takada G, Inagaki N.
Journal: Mol Genet Metab (2006): 113

Imprinting at the SMPD1 locus: implications for acid sphingomyelinase-deficient Niemann-Pick disease
Authors: Simonaro CM, Park JH, Eliyahu E, Shtraizent N, McGovern MM, Schuchman EH.
Journal: Am J Hum Genet (2006): 865

Changes in sphingomyelinase activity, tumor necrosis factor alpha level, and lipid peroxidation rate in the course of development of cholestatic liver injury
Authors: Dudnik LB, Tsiupko AN, Shingarova LN, Shupik MA, Akhaladze GG, Gal'perin EI, Platonova LV, Shono NI, Iasnetsov VV, Alesenko AV.
Journal: Izv Akad Nauk Ser Biol (2005): 650

Acid sphingomyelinase is induced by butyrate but does not initiate the anticancer effect of butyrate in HT29 and HepG2 cells
Authors: Wu J, Cheng Y, Jonsson BA, Nilsson A, Duan RD.
Journal: J Lipid Res (2005): 1944

Elevated sphingomyelinase activity and ceramide concentration in serum of patients undergoing high dose spatially fractionated radiation treatment: implications for endothelial apoptosis
Authors: Sathishkumar S, Boyanovsky B, Karakashian AA, Rozenova K, Giltiay NV, Kudrimoti M, Mohiuddin M, Ahmed MM, Nikolova-Karakashian M.
Journal: Cancer Biol Ther (2005): 979

Sphingomyelinase induces aggregation and fusion of small very low-density lipoprotein and intermediate-density lipoprotein particles and increases their retention to human arterial proteoglycans
Authors: Oorni K, Posio P, Ala-Korpela M, Jauhiainen M, Kovanen PT.
Journal: Arterioscler Thromb Vasc Biol (2005): 1678

Sphingomyelinase D from venoms of Loxosceles spiders: evolutionary insights from cDNA sequences and gene structure
Authors: Binford GJ, Cordes MH, Wells MA.
Journal: Toxicon (2005): 547

Role of increased sphingomyelinase activity in apoptosis and organ failure of patients with severe sepsis
Authors: Claus RA, Bunck AC, Bockmeyer CL, Brunkhorst FM, Losche W, Kinscherf R, Deigner HP.
Journal: Faseb J (2005): 1719

A new fluorimetric enzyme assay for the diagnosis of Niemann-Pick A/B, with specificity of natural sphingomyelinase substrate
Authors: van Diggelen OP, Voznyi YV, Keulemans JL, Schoonderwoerd K, Ledvinova J, Mengel E, Zschiesche M, Santer R, Harzer K.
Journal: J Inherit Metab Dis (2005): 733

Detection of alkaline sphingomyelinase activity in human stool: proposed role as a new diagnostic and prognostic marker of colorectal cancer
Authors: Di Marzio L, Di Leo A, Cinque B, Fanini D, Agnifili A, Berloco P, Linsalata M, Lorusso D, Barone M, De Simone C, Cifone MG.
Journal: Cancer Epidemiol Biomarkers Prev (2005): 856

Loxosceles sphingomyelinase induces complement-dependent dermonecrosis, neutrophil infiltration, and endogenous gelatinase expression
Authors: Tambourgi DV, Paixao-Cavalcante D, Goncalves de Andrade RM, Fern and es-Pedrosa Mde F, Magnoli FC, Paul Morgan B, van den Berg CW.
Journal: J Invest Dermatol (2005): 725

Regulatory roles of cell surface sialylation in susceptibility to sphingomyelinase in human diffuse large B cell lymphoma
Authors: Suzuki O, Nozawa Y, Abe M.
Journal: Int J Oncol (2005): 209

A novel high-throughput screening format to identify inhibitors of secreted acid sphingomyelinase
Authors: Mintzer RJ, Appell KC, Cole A, Johns A, Pagila R, Polokoff MA, Tabas I, Snider RM, Meurer-Ogden JA.
Journal: J Biomol Screen (2005): 225

High activity of acid sphingomyelinase in major depression
Authors: Kornhuber J, Medlin A, Bleich S, Jendrossek V, Henkel AW, Wiltfang J, Gulbins E.
Journal: J Neural Transm (2005): 1583

Preimplantation diagnosis of a lysosomal storage disorder by in situ enzymatic activity: 'proof of principle' in acid sphingomyelinase-deficient mice
Authors: Butler A, Henderson SC, Gordon RE, Dagan A, Gatt S, Schuchman EH.
Journal: J Inherit Metab Dis (2005): 1

Sphingomyelinase causes endothelium-dependent vasorelaxation through endothelial nitric oxide production without cytosolic Ca(2+) elevation
Authors: Mogami K, Kishi H, Kobayashi S.
Journal: FEBS Lett (2005): 393

Identification of three competitive inhibitors for membrane-associated, Mg2+-dependent and neutral 60 kDa sphingomyelinase activity
Authors: Kim SK, Jung SM, Ahn KH, Jeon HJ, Lee DH, Jung KM, Jung SY, Kim DK.
Journal: Arch Pharm Res (2005): 923

Amyloid-beta peptide enhances tumor necrosis factor-alpha-induced iNOS through neutral sphingomyelinase/ceramide pathway in oligodendrocytes
Authors: Zeng C, Lee JT, Chen H, Chen S, Hsu CY, Xu J.
Journal: J Neurochem (2005): 703

Functional characterization of the postulated intramolecular sphingolipid activator protein domain of human acid sphingomyelinase
Authors: Kolzer M, Ferlinz K, Bartelsen O, Hoops SL, Lang F, S and hoff K., undefined
Journal: Biol Chem (2004): 1193