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African swine fever virus B175L inhibits the type I interferon pathway by targeting STING and 2′ 3′-cGAMP
Authors: Ranathunga, Lakmal and Dodantenna, Niranjan and Cha, Ji-Won and Chathuranga, Kiramage and Chathuranga, WA Gayan and Weerawardhana, Asela and Subasinghe, Ashan and Haluwana, DK and Gamage, Nuwan and Lee, Jong-Soo
Journal: Journal of Virology (2023): e00795--23

African Swine Fever Virus EP364R and C129R Target Cyclic GMP-AMP To Inhibit the cGAS-STING Signaling Pathway
Authors: Dodantenna, Niranjan and Ranathunga, Lakmal and Chathuranga, WA Gayan and Weerawardhana, Asela and Cha, Ji-Won and Subasinghe, Ashan and Gamage, Nuwan and Haluwana, DK and Kim, YongKwan and Jheong, WeonHwa and others,
Journal: Journal of Virology (2022): e01022--22

The cGAS-cGAMP-STING Pathway: A Molecular Link Between Immunity and Metabolism
Authors: Bai, J., Liu, F.
Journal: Diabetes (2019): 1099-1108

Efficacy and mechanism of cGAMP to suppress Alzheimer's disease by elevating TREM2
Authors: Xu, Q., Xu, W., Cheng, H., Yuan, H., Tan, X.
Journal: Brain Behav Immun (2019): se name="20310.enl" path="C:\Users\aatbi\Drop

Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING
Authors: Siu, T., Altman, M. D., Baltus, G. A., Childers, M., Ellis, J. M., Gunaydin, H., Hatch, H., Ho, T., Jewell, J., Lacey, B. M., Lesburg, C. A., Pan, B. S., Sauvagnat, B., Schroeder, G. K., Xu, S.
Journal: ACS Med Chem Lett (2019): 92-97

Publisher Correction: Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling
Authors: Eaglesham, J. B., Pan, Y., Kupper, T. S., Kranzusch, P. J.
Journal: Nature (2019): E12

The STING ligand cGAMP potentiates the efficacy of vaccine-induced CD8+ T cells
Authors: Gutjahr, A., Papagno, L., Nicoli, F., Kanuma, T., Kuse, N., Cabral-Piccin, M. P., Rochereau, N., Gostick, E., Lioux, T., Perouzel, E., Price, D. A., Takiguchi, M., Verrier, B., Yamamoto, T., Paul, S., Appay, V.
Journal: JCI Insight (2019): se name="20310.enl" path="C:\Users\aatbi\Drop

SLC19A1 Is an Importer of the Immunotransmitter cGAMP
Authors: Ritchie, C., Cordova, A. F., Hess, G. T., Bassik, M. C., Li, L.
Journal: Mol Cell (2019): 372-381 e5

A Click-Chemistry Linked 2'3'-cGAMP Analogue
Authors: Dialer, C. R., Stazzoni, S., Drexler, D. J., Muller, F. M., Veth, S., Pichler, A., Okamura, H., Witte, G., Hopfner, K. P., Carell, T.
Journal: Chemistry (2019): 2089-2095

Distinct Dynamic and Conformational Features of Human STING in Response to 2'3'-cGAMP and c-di-GMP
Authors: Guo, J., Wang, J., Fan, J., Zhang, Y., Dong, W., Chen, C. P.
Journal: Chembiochem (2019): 1838-1847

A Poxin on Both of Your Houses: Poxviruses Degrade the Immune Signal cGAMP
Authors: Dippel, A. B., Hammond, M. C.
Journal: Biochemistry (2019): 2387-2388

Structure and mechanism of a Hypr GGDEF enzyme that activates cGAMP signaling to control extracellular metal respiration
Authors: Hallberg, Z. F., Chan, C. H., Wright, T. A., Kranzusch, P. J., Doxzen, K. W., Park, J. J., Bond, D. R., Hammond, M. C.
Journal: Elife (2019): se name="20310.enl" path="C:\Users\aatbi\Drop

Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling
Authors: Eaglesham, J. B., Pan, Y., Kupper, T. S., Kranzusch, P. J.
Journal: Nature (2019): 259-263

Global transcriptional changes in response to cGAMP depend on STING in human THP-1 cells
Authors: Hansen, A. L., Br and toft, A. M., Nyegaard, M., Thielke, A. L., Olagnier, D., Holm, C. K.
Journal: Cell Mol Immunol (2018): 983-985

Corrigendum: Human Cytomegalovirus IE2 86 kDa Protein Induces STING Degradation and Inhibits cGAMP-Mediated IFN-beta Induction
Authors: Kim, J. E., Kim, Y. E., Stinski, M. F., Ahn, J. H., Song, Y. J.
Journal: Front Microbiol (2018): 350

Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1
Authors: Kato, K., Nishimasu, H., Oikawa, D., Hirano, S., Hirano, H., Kasuya, G., Ishitani, R., Tokunaga, F., Nureki, O.
Journal: Nat Commun (2018): 4424

Assessing the cGAS-cGAMP-STING Activity of Cancer Cells
Authors: Pepin, G., Gantier, M. P.
Journal: Methods Mol Biol (2018): 257-266

Tumor cGAMP Awakens the Natural Killers
Authors: Sundararaman, S. K., Barbie, D. A.
Journal: Immunity (2018): 585-587

A novel nanocomposite based on fluorescent turn-on gold nanostars for near-infrared photothermal therapy and self-theranostic caspase-3 imaging of glioblastoma tumor cell
Authors: Wang, J., Zhou, Z., Zhang, F., Xu, H., Chen, W., Jiang, T.
Journal: Colloids Surf B Biointerfaces (2018): 303-311

Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response
Authors: Marcus, A., Mao, A. J., Lensink-Vasan, M., Wang, L., Vance, R. E., Raulet, D. H.
Journal: Immunity (2018): 754-763 e4

Structural Studies of the 3',3'-cGAMP Riboswitch Induced by Cognate and Noncognate Ligands Using Molecular Dynamics Simulation
Authors: Li, C., Zhao, X., Zhu, X., Xie, P., Chen, G.
Journal: Int J Mol Sci (2018): se name="20310.enl" path="C:\Users\aatbi\Drop

Suramin potently inhibits cGAMP synthase, cGAS, in THP1 cells to modulate IFN-beta levels
Authors: Wang, M., Sooreshjani, M. A., Mikek, C., Opoku-Temeng, C., Sintim, H. O.
Journal: Future Med Chem (2018): 1301-1317

Corrigendum: Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer
Authors: Chen, Q., Boire, A., Jin, X., Valiente, M., Emrah Er, E., Lopez-Soto, A., Jacob, L. S., Patwa, R., Shah, H., Xu, K., Cross, J. R., Massague, J.
Journal: Nature (2017): 124

Sublingual targeting of STING with 3'3'-cGAMP promotes systemic and mucosal immunity against anthrax toxins
Authors: Martin, T. L., Jee, J., Kim, E., Steiner, H. E., Cormet-Boyaka, E., Boyaka, P. N.
Journal: Vaccine (2017): 2511-2519

Intracellular DNA sensing pathway of cGAS-cGAMP is decreased in human newborns and young children
Authors: Wang, Z. S., Liu, Y. L., Mi, N., Duan, D. Y.
Journal: Mol Immunol (2017): 76-85

The Chemistry of the Noncanonical Cyclic Dinucleotide 2'3'-cGAMP and Its Analogs
Authors: Schwede, F., Genieser, H. G., Rentsch, A.
Journal: Handb Exp Pharmacol (2017): 359-384

cGAMP Quantification in Virus-Infected Human Monocyte-Derived Cells by HPLC-Coupled Tandem Mass Spectrometry
Authors: Paijo, J., Kaever, V., Kalinke, U.
Journal: Methods Mol Biol (2017): 153-166

cGAMP: A tale of two signals
Authors: Kuriakose, T., Kanneganti, T. D.
Journal: J Exp Med (2017): 3471-3473

Intranasal immunization of pigs with porcine reproductive and respiratory syndrome virus-like particles plus 2', 3'-cGAMP VacciGrade adjuvant exacerbates viremia after virus challenge
Authors: Van Noort, A., Nelsen, A., Pillatzki, A. E., Diel, D. G., Li, F., Nelson, E., Wang, X.
Journal: Virol J (2017): 76

Ester alkaloids from Cephalotaxus interfere with the 2'3'-cGAMP-induced type I interferon pathway in vitro
Authors: Park, G., Kim, S. Y., Song, Y. J.
Journal: PLoS One (2017): e0182701

IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP
Authors: Jonsson, K. L., Laustsen, A., Krapp, C., Skipper, K. A., Thavachelvam, K., Hotter, D., Egedal, J. H., Kjolby, M., Mohammadi, P., Prabakaran, T., Sorensen, L. K., Sun, C., Jensen, S. B., Holm, C. K., Lebbink, R. J., Johannsen, M., Nyegaard, M., Mikkelsen, J. G., Kirchhoff, F., Paludan, S. R., Jakobsen, M. R.
Journal: Nat Commun (2017): 14391

cGAMP Promotes Germinal Center Formation and Production of IgA in Nasal-Associated Lymphoid Tissue
Authors: Takaki, H., Takashima, K., Oshiumi, H., Ainai, A., Suzuki, T., Hasegawa, H., Matsumoto, M., Seya, T.
Journal: Med Sci (Basel) (2017): se name="20310.enl" path="C:\Users\aatbi\Drop

DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway
Authors: Bai, J., Cervantes, C., Liu, J., He, S., Zhou, H., Zhang, B., Cai, H., Yin, D., Hu, D., Li, Z., Chen, H., Gao, X., Wang, F., O'Connor, J. C., Xu, Y., Liu, M., Dong, L. Q., Liu, F.
Journal: Proc Natl Acad Sci U S A (2017): 12196-12201

A noncanonical function of cGAMP in inflammasome priming and activation
Authors: Swanson, K. V., Junkins, R. D., Kurkjian, C. J., Holley-Guthrie, E., Pendse, A. A., El Morabiti, R., Petrucelli, A., Barber, G. N., Benedict, C. A., Ting, J. P.
Journal: J Exp Med (2017): 3611-3626

Human Cytomegalovirus IE2 86 kDa Protein Induces STING Degradation and Inhibits cGAMP-Mediated IFN-beta Induction
Authors: Kim, J. E., Kim, Y. E., Stinski, M. F., Ahn, J. H., Song, Y. J.
Journal: Front Microbiol (2017): 1854

Intratumoral administration of cGAMP transiently accumulates potent macrophages for anti-tumor immunity at a mouse tumor site
Authors: Ohkuri, T., Kosaka, A., Ishibashi, K., Kumai, T., Hirata, Y., Ohara, K., Nagato, T., Oikawa, K., Aoki, N., Harabuchi, Y., Celis, E., Kobayashi, H.
Journal: Cancer Immunol Immunother (2017): 705-716

Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer
Authors: Chen, Q., Boire, A., Jin, X., Valiente, M., Er, E. E., Lopez-Soto, A., Jacob, L., Patwa, R., Shah, H., Xu, K., Cross, J. R., Massague, J.
Journal: Nature (2016): 493-498

Hybrid promiscuous (Hypr) GGDEF enzymes produce cyclic AMP-GMP (3', 3'-cGAMP)
Authors: Hallberg, Z. F., Wang, X. C., Wright, T. A., Nan, B., Ad, O., Yeo, J., Hammond, M. C.
Journal: Proc Natl Acad Sci U S A (2016): 1790-5

Cyclic dinucleotide (c-di-GMP, c-di-AMP, and cGAMP) signalings have come of age to be inhibited by small molecules
Authors: Opoku-Temeng, C., Zhou, J., Zheng, Y., Su, J., Sintim, H. O.
Journal: Chem Commun (Camb) (2016): 9327-42

An RNA-Based Fluorescent Biosensor for High-Throughput Analysis of the cGAS-cGAMP-STING Pathway
Authors: Bose, D., Su, Y., Marcus, A., Raulet, D. H., Hammond, M. C.
Journal: Cell Chem Biol (2016): 1539-1549

cGAS-cGAMP-STING: The three musketeers of cytosolic DNA sensing and signaling
Authors: Tao, J., Zhou, X., Jiang, Z.
Journal: IUBMB Life (2016): 858-870

Antitumor Activity of cGAMP via Stimulation of cGAS-cGAMP-STING-IRF3 Mediated Innate Immune Response
Authors: Li, T., Cheng, H., Yuan, H., Xu, Q., Shu, C., Zhang, Y., Xu, P., Tan, J., Rui, Y., Li, P., Tan, X.
Journal: Sci Rep (2016): 19049

V-cGAPs: attenuators of 3'3'-cGAMP signaling
Authors: Gao, P., Patel, D. J.
Journal: Cell Res (2015): 529-30

Corrigendum: Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs
Authors: Li, L., Yin, Q., Kuss, P., Maliga, Z., Millan, J. L., Wu, H., Mitchison, T. J.
Journal: Nat Chem Biol (2015): 235

Erratum: Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs
Authors: Li, L., Yin, Q., Kuss, P., Maliga, Z., Millan, J. L., Wu, H., Mitchison, T. J.
Journal: Nat Chem Biol (2015): 741

Inside Job: Viruses Transfer cGAMP between Cells
Authors: Gulen, M. F., Ablasser, A.
Journal: Cell Host Microbe (2015): 263-5

Transmission of innate immune signaling by packaging of cGAMP in viral particles
Authors: Gentili, M., Kowal, J., Tkach, M., Satoh, T., Lahaye, X., Conrad, C., Boyron, M., Lombard, B., Dur and , S., Kroemer, G., Loew, D., Dalod, M., Thery, C., Manel, N.
Journal: Science (2015): 1232-6

Structural basis for molecular discrimination by a 3',3'-cGAMP sensing riboswitch
Authors: Ren, A., Wang, X. C., Kellenberger, C. A., Rajashankar, K. R., Jones, R. A., Hammond, M. C., Patel, D. J.
Journal: Cell Rep (2015): 1-12

Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling
Authors: Kranzusch, P. J., Wilson, S. C., Lee, A. S., Berger, J. M., Doudna, J. A., Vance, R. E.
Journal: Mol Cell (2015): 891-903

Viruses transfer the antiviral second messenger cGAMP between cells
Authors: Bridgeman, A., Maelfait, J., Davenne, T., Partridge, T., Peng, Y., Mayer, A., Dong, T., Kaever, V., Borrow, P., Rehwinkel, J.
Journal: Science (2015): 1228-32

A cyclic dinucleotide containing 2-aminopurine is a general fluorescent sensor for c-di-GMP and 3',3'-cGAMP
Authors: Roembke, B. T., Zhou, J., Zheng, Y., Sayre, D., Lizardo, A., Bernard, L., Sintim, H. O.
Journal: Mol Biosyst (2014): 1568-75

DMXAA causes tumor site-specific vascular disruption in murine non-small cell lung cancer, and like the endogenous non-canonical cyclic dinucleotide STING agonist, 2'3'-cGAMP, induces M2 macrophage repolarization
Authors: Downey, C. M., Aghaei, M., Schwendener, R. A., Jirik, F. R.
Journal: PLoS One (2014): e99988

The cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signaling
Authors: Cai, X., Chiu, Y. H., Chen, Z. J.
Journal: Mol Cell (2014): 289-96

Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs
Authors: Li, L., Yin, Q., Kuss, P., Maliga, Z., Millan, J. L., Wu, H., Mitchison, T. J.
Journal: Nat Chem Biol (2014): 1043-8

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects
Authors: Li, X. D., Wu, J., Gao, D., Wang, H., Sun, L., Chen, Z. J.
Journal: Science (2013): 1390-4

Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP
Authors: Ablasser, A., Schmid-Burgk, J. L., Hemmerling, I., Horvath, G. L., Schmidt, T., Latz, E., Hornung, V.
Journal: Nature (2013): 530-4