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Contact-dependent signaling triggers tumor-like proliferation of CCM3 knockout endothelial cells in co-culture with wild-type cells
Authors: Rath, Matthias and Schwefel, Konrad and Malinverno, Matteo and Skowronek, Dariush and Leopoldi, Alexandra and Pilz, Robin A and Biedenweg, Doreen and Bekeschus, Sander and Penninger, Josef M and Dejana, Elisabetta and others,
Journal: Cellular and Molecular Life Sciences (2022): 1--20

Combination of Goniothalamin and Sol-Gel-Derived Bioactive Glass 45S5 Enhances Growth Inhibitory Activity via Apoptosis Induction and Cell Cycle Arrest in Breast Cancer Cells MCF-7
Authors: Bakar, Siti Aishah Abu and Ali, Abdul Manaf and Noor, Siti Noor Fazliah Mohd and Hamid, Shahrul Bariyah Sahul and Azhar, Nur Asna and Mohamad, Noor Muzamil and Ahmad, Nor Hazwani
Journal: BioMed Research International (2022)

The BH3 mimetic ($\pm$) gossypol induces ROS-independent apoptosis and mitochondrial dysfunction in human A375 melanoma cells in vitro
Authors: Haasler, Lisa and Kondadi, Arun Kumar and Tsigaras, Thanos and von Montfort, Claudia and Graf, Peter and Stahl, Wilhelm and Brenneisen, Peter
Journal: Archives of Toxicology (2021): 1349--1365

Discovery of substituted N'-(2-oxoindolin-3-ylidene)benzohydrazides as new apoptosis inducers using a cell- and caspase-based HTS assay
Authors: Sirisoma N, Pervin A, Drewe J, Tseng B, Cai SX.
Journal: Bioorg Med Chem Lett (2009): 2710

Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2: Structure-activity relationships of the 4-, 5-, 6-, 7- and 8-positions
Authors: Kemnitzer W, Kuemmerle J, Jiang S, Sirisoma N, Kasibhatla S, Crogan-Grundy C, Tseng B, Drewe J, Cai SX.
Journal: Bioorg Med Chem Lett (2009): 3481

Selective identification of cooperatively binding fragments in a high-throughput ligation assay enables development of a picomolar caspase-3 inhibitor
Authors: Schmidt MF, El-Dahshan A, Keller S, Rademann J.
Journal: Angew Chem Int Ed Engl (2009): 6346

Modified caspase-3 assay indicates correlation of caspase-3 activity with immunity of nonhuman primates to Yersinia pestis infection
Authors: Welkos S, Norris S, Adamovicz J.
Journal: Clin Vaccine Immunol (2008): 1134

Liver apoptosis following normothermic ischemia-reperfusion: in vivo evaluation of caspase activity by FLIVO assay in rats
Authors: Cursio R, Colosetti P, Auberger P, Gugenheim J.
Journal: Transplant Proc (2008): 2038

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 4. Structure-activity relationships of N-alkyl substituted pyrrole fused at the 7,8-positions
Authors: Kemnitzer W, Drewe J, Jiang S, Zhang H, Crogan-Grundy C, Labreque D, Bubenick M, Attardo G, Denis R, Lamothe S, Gourdeau H, Tseng B, Kasibhatla S, Cai SX.
Journal: J Med Chem (2008): 417

Discovery of (naphthalen-4-yl)(phenyl)methanones and N-methyl-N-phenylnaphthalen-1-amines as new apoptosis inducers using a cell- and caspase-based HTS assay
Authors: Jiang S, Crogan-Grundy C, Drewe J, Tseng B, Cai SX.
Journal: Bioorg Med Chem Lett (2008): 5725

A dual-step fluorescence resonance energy transfer-based quenching assay for screening of caspase-3 inhibitors
Authors: Valanne A, Malmi P, Appelblom H, Niemela P, Soukka T.
Journal: Anal Biochem (2008): 71

Discovery of 5-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-7-phenyl-(E)-2,3,6,7-tetrahydro -1,4-thiazepines as a new series of apoptosis inducers using a cell- and caspase-based HTS assay
Authors: Drewe J, Kasibhatla S, Tseng B, Shelton E, Sper and io D, Yee RM, Litvak J, Sendzik M, Spencer JR, Cai SX.
Journal: Bioorg Med Chem Lett (2007): 4987

Split GFP complementation assay: a novel approach to quantitatively measure aggregation of tau in situ: effects of GSK3beta activation and caspase 3 cleavage
Authors: Chun W, Waldo GS, Johnson GV.
Journal: J Neurochem (2007): 2529

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 3. Structure-activity relationships of fused rings at the 7,8-positions
Authors: Kemnitzer W, Drewe J, Jiang S, Zhang H, Zhao J, Crogan-Grundy C, Xu L, Lamothe S, Gourdeau H, Denis R, Tseng B, Kasibhatla S, Cai SX.
Journal: J Med Chem (2007): 2858

Correlating the fractional inhibition of caspase-3 in NT2 cells with apoptotic markers using an active-caspase-3 enzyme-linked immunosorbent assay
Authors: Tawa P, Giroux A, Grimm E, Han Y, Nicholson DW, Xanthoudakis S.
Journal: Anal Biochem (2006): 32

Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: structure-activity relationships of the 4-anilino group
Authors: Sirisoma N, Kasibhatla S, Nguyen B, Pervin A, Wang Y, Claassen G, Tseng B, Drewe J, Cai SX.
Journal: Bioorg Med Chem (2006): 7761

A sensitive flow cytometry-based cytotoxic T-lymphocyte assay through detection of cleaved caspase 3 in target cells
Authors: He L, Hakimi J, Salha D, Miron I, Dunn P, Radvanyi L.
Journal: J Immunol Methods (2005): 43

N-DEVD-N'-morpholinecarbonyl-rhodamine 110: novel caspase-3 fluorogenic substrates for cell-based apoptosis assay
Authors: Wang ZQ, Liao J, Diwu Z.
Journal: Bioorg Med Chem Lett (2005): 2335

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 7- and 5-, 6-, 8-positions
Authors: Kemnitzer W, Kasibhatla S, Jiang S, Zhang H, Zhao J, Jia S, Xu L, Crogan-Grundy C, Denis R, Barriault N, Vaillancourt L, Charron S, Dodd J, Attardo G, Labrecque D, Lamothe S, Gourdeau H, Tseng B, Drewe J, Cai SX.
Journal: Bioorg Med Chem Lett (2005): 4745

Detection of programmed cell death in cells exposed to genotoxic agents using a caspase activation assay
Authors: Gehring ME, Koty PP.
Journal: Methods Mol Biol (2005): 465

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the 4-aryl group
Authors: Kemnitzer W, Drewe J, Jiang S, Zhang H, Wang Y, Zhao J, Jia S, Herich J, Labreque D, Storer R, Meerovitch K, Bouffard D, Rej R, Denis R, Blais C, Lamothe S, Attardo G, Gourdeau H, Tseng B, Kasibhatla S, Cai SX.
Journal: J Med Chem (2004): 6299

Caspase multiplexing: simultaneous homogeneous time-resolved quenching assay (TruPoint) for caspases 1, 3, and 6
Authors: Karvinen J, Elomaa A, Makinen ML, Hakala H, Mukkala VM, Peuralahti J, Hurskainen P, Hovinen J, Hemmila I.
Journal: Anal Biochem (2004): 317

Measurement of CTL-induced cytotoxicity: the caspase 3 assay
Authors: Jerome KR, Sloan DD, Aubert M.
Journal: Apoptosis (2003): 563

Discovery of substituted N-phenyl nicotinamides as potent inducers of apoptosis using a cell- and caspase-based high throughput screening assay
Authors: Cai SX, Nguyen B, Jia S, Herich J, Guastella J, Reddy S, Tseng B, Drewe J, Kasibhatla S.
Journal: J Med Chem (2003): 2474

One-step cellular caspase-3/7 assay
Authors: Carrasco RA, Stamm NB, Patel BK.
Journal: Biotechniques (2003): 1064

Caspase-3 colorimetric assay
Authors: Zeng L, Smith LD.
Journal: Biotechniques (2002): 1196

Homogeneous time-resolved fluorescence quenching assay (LANCE) for caspase-3
Authors: Karvinen J, Hurskainen P, Gopalakrishnan S, Burns D, Warrior U, Hemmila I.
Journal: J Biomol Screen (2002): 223

A homogeneous caspase-3 activity assay using HTRF technology
Authors: Preaudat M, Ouled-Diaf J, Alpha-Bazin B, Mathis G, Mitsugi T, Aono Y, Takahashi K, Takemoto H.
Journal: J Biomol Screen (2002): 267

Assay of caspase activation in situ combined with probing plasma membrane integrity to detect three distinct stages of apoptosis
Authors: Smolewski P, Grabarek J, Halicka HD, Darzynkiewicz Z.
Journal: J Immunol Methods (2002): 111

Design and synthesis of rhodamine 110 derivative and caspase-3 substrate for enzyme and cell-based fluorescent assay
Authors: Cai SX, Zhang HZ, Guastella J, Drewe J, Yang W, Weber E.
Journal: Bioorg Med Chem Lett (2001): 39

Development and application of a GFP-FRET intracellular caspase assay for drug screening
Authors: Jones J, Heim R, Hare E, Stack J, Pollok BA.
Journal: J Biomol Screen (2000): 307

A yeast genetic assay for caspase cleavage of the amyloid-beta precursor protein
Authors: Gunyuzlu PL, White WH, Davis GL, Hollis GF, Toyn JH.
Journal: Mol Biotechnol (2000): 29

Application of a fluorometric assay to detect caspase activity in thymus tissue undergoing apoptosis in vivo
Authors: Gorman AM, Hirt UA, Zhivotovsky B, Orrenius S, Ceccatelli S.
Journal: J Immunol Methods (1999): 43

Synthesis and evaluation of isatin analogs as caspase-3 inhibitors: introduction of a hydrophilic group increases potency in a whole cell assay
Authors: Chu W, Rothfuss J, Zhou D, Mach RH
Journal: Bioorg Med Chem Lett : 2192