AAT Bioquest offers a comprehensive selection of Drug-KLH Conjugates designed for developing drug-specific antibodies used in ELISA-based detection assays. Keyhole Limpet Hemocyanin (KLH) is an excellent carrier protein due to its high molecular weight and strong immunogenicity, making it ideal for generating robust immune responses against small molecule haptens such as antibiotics, opioids, and other pharmaceutical compounds. These ready-to-use conjugates eliminate the complexity of custom conjugation chemistry, providing researchers with reliable immunogens for antibody production and immunoassay development.

Antibiotic-KLH conjugates are essential immunogens for developing antibodies against antimicrobial drug residues in food, environmental, and clinical samples. These conjugates enable researchers to create sensitive ELISA-based screening assays for monitoring antibiotic contamination in meat, milk, eggs, and aquaculture products. AAT Bioquest provides conjugates covering multiple antibiotic classes including amphenicols, fluoroquinolones, and sulfonamides.

Nitrofuran metabolite-KLH conjugates are designed for developing antibodies against tissue-bound metabolites of banned nitrofuran antibiotics. Nitrofurans (furazolidone, furaltadone, nitrofurantoin, and nitrofurazone) are prohibited in food-producing animals due to potential carcinogenic and mutagenic properties. Since parent compounds degrade rapidly, detection relies on identifying their stable protein-bound metabolites: AOZ, AMOZ, AHD, and SEM.

Opioid and controlled substance-KLH conjugates support the development of antibodies for forensic toxicology, clinical drug monitoring, and drug abuse testing applications. These conjugates are particularly critical for addressing the ongoing opioid crisis, enabling sensitive detection of fentanyl, its metabolites, and emerging synthetic opioids in biological specimens.

Sedative and anesthetic-KLH conjugates enable development of immunoassays for detecting veterinary sedatives and emerging adulterants in drug supply monitoring. Xylazine, in particular, has become a critical target due to its increasing prevalence as a fentanyl adulterant, while medetomidine and diazepam remain important for veterinary drug residue testing.

This category includes hormone conjugates and specialty drug-KLH products for various immunoassay applications, from steroid hormone detection to ionophore antibiotic monitoring in animal products. These conjugates provide researchers with targeted solutions for hormone-based and specialized pharmaceutical immunogens.

AAT Bioquest provides high-quality KLH carrier proteins and conjugation kits for researchers who need to prepare custom drug-protein conjugates. These products offer flexibility for immunizing with haptens not available as pre-made conjugates, enabling researchers to develop immunogens for their specific applications.