6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	2-Amino-N-[4-(2-amino-3-cyano-1-ethylindol-5-yl)oxyphenyl]acetamide	IC50	9180.0 [1]
	2-Amino-N-[4-(2-amino-3-cyano-1-methylindol-5-yl)oxyphenyl]acetamide	IC50	21100.0 [1]
	(2R)-2-Amino-N-[4-[(2-amino-3-cyano-1H-indol-5-yl)oxy]phenyl]-3-hydroxypropanamide	IC50	100000.0 [1]
	2-Amino-N-[4-[2-amino-3-cyano-1-[2-(dimethylamino)-2-oxoethyl]indol-5-yl]oxyphenyl]acetamide	IC50	6840.0 [1]
	2-Amino-N-[4-(3-cyano-1-ethylindol-5-yl)oxyphenyl]acetamide	IC50	22800.0 [1]
	(2s)-2-Amino-N-[4-[(2-Amino-3-Cyano-1h-Indol-5-Yl)oxy]phenyl]-3-Hydroxy-Propanamide	IC50	26900.0 [1]
	(2S)-N-[4-[[3-Cyano-1-(2-methylpropyl)indol-5-yl]amino]phenyl]pyrrolidine-2-carboxamide	IC50	6150.0 [1]
	(2S)-N-[4-[[3-Cyano-1-(2-methylpropyl)indol-5-yl]-methylamino]phenyl]pyrrolidine-2-carboxamide	IC50	141.0 [1]
	(2S)-N-[4-[3-Cyano-1-(2-methylpropyl)indol-5-yl]sulfanylphenyl]pyrrolidine-2-carboxamide	IC50	190.0 [1]
	(2S)-N-[4-[3-Cyano-1-(2-methylpropyl)indol-5-yl]sulfonylphenyl]pyrrolidine-2-carboxamide	IC50	100000.0 [1]
	(2S)-N-[4-[[3-Cyano-1-(2-methylpropyl)indol-5-yl]methyl]phenyl]pyrrolidine-2-carboxamide	IC50	1450.0 [1]
	AZ Pfkfb3 26	IC50	384.0 [1]
	2-Amino-N-[4-[2-amino-3-cyano-1-(2-methylpropyl)indol-5-yl]oxyphenyl]acetamide	IC50	2520.0 [1]
	N-[4-(3-Cyano-1-ethylindol-5-yl)oxyphenyl]-2-(methylamino)acetamide	IC50	24890.0 [1]
	N-[4-(3-Cyano-1-ethylindol-5-yl)oxyphenyl]-2-(dimethylamino)acetamide	IC50	76100.0 [1]
	(2S)-N-[4-(3-Cyano-1-ethylindol-5-yl)oxyphenyl]pyrrolidine-2-carboxamide	IC50	1820.0 [1]
	(2R)-N-[4-(3-Cyano-1-ethylindol-5-yl)oxyphenyl]pyrrolidine-2-carboxamide	IC50	100000.0 [1]
	(2S)-N-[4-(3-Cyano-1-ethylindol-5-yl)oxyphenyl]-N-methylpyrrolidine-2-carboxamide	IC50	76500.0 [1]
	(2S)-N-[4-(3-Cyano-1-ethylindol-5-yl)oxyphenyl]piperidine-2-carboxamide	IC50	22000.0 [1]
	(2S)-N-[4-(3-Cyano-1-ethylindol-5-yl)oxyphenyl]-N-methyl-5-oxopyrrolidine-2-carboxamide	IC50	23700.0 [1]
	(2S)-N-[4-[3-Cyano-1-[2-(methylamino)-2-oxoethyl]indol-5-yl]oxyphenyl]pyrrolidine-2-carboxamide	IC50	2350.0 [1]
	(2S)-N-[4-[3-Cyano-1-[2-(dimethylamino)ethyl]indol-5-yl]oxyphenyl]pyrrolidine-2-carboxamide	IC50	100000.0 [1]
	(2S)-N-[4-[3-Cyano-1-(oxan-4-ylmethyl)indol-5-yl]oxyphenyl]pyrrolidine-2-carboxamide	IC50	429.0 [1]
	(2S)-N-[4-(3-Cyano-1-phenylindol-5-yl)oxyphenyl]pyrrolidine-2-carboxamide	IC50	374.0 [1]
	(2S)-N-[4-[3-Cyano-1-(2-methyl-1-oxo-3H-isoindol-5-yl)indol-5-yl]oxyphenyl]pyrrolidine-2-carboxamide	IC50	108.0 [1]
	(2S)-N-[4-(1-Benzyl-3-cyanoindol-5-yl)oxyphenyl]pyrrolidine-2-carboxamide	IC50	188.0 [1]
	(2S)-N-[4-[3-Cyano-1-(2-methylpropyl)indazol-5-yl]oxyphenyl]pyrrolidine-2-carboxamide	IC50	15.0 [1]
	(2S)-N-[4-[3-Cyano-1-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]indazol-5-yl]oxyphenyl]pyrrolidine-2-carboxamide	IC50	25.0 [1]
	2-Amino-N-[4-[[3-(1-methylpyrazol-4-yl)-1H-indazol-5-yl]oxy]phenyl]acetamide	IC50	11800.0 [1]
	(2S)-N-[4-[[3-(1-Methylpyrazol-4-yl)-1H-indol-5-yl]oxy]phenyl]pyrrolidine-2-carboxamide	IC50	3570.0 [1]
	2-Amino-N-[4-(2-Amino-1-Benzyl-3-Cyano-Indol-5-Yl)oxyphenyl]acetamide	IC50	1480.0 [1]
	CID 91668554	IC50	159.0 [1]
	2-Azanyl-N-[4-[(3-Cyano-1h-Indol-5-Yl)oxy]phenyl]ethanamide	IC50	63200.0 [1]
	(2s)-N-[4-[1-Methyl-3-(1-Methylpyrazol-4-Yl)indol-5-Yl]oxyphenyl]pyrrolidine-2-Carboxamide	IC50	818.0 [1]
	5-(4-Acetylaminophenoxy)-2-amino-1H-indole-3-carbonitrile	IC50	100000.0 [1]
	2-Amino-N-[4-[(2-amino-3-cyano-1H-indol-5-yl)oxy]phenyl]acetamide	IC50	53800.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 36 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/6-phosphofructo-2-kinase-fructose-2-6-bisphosphatase-2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/6-phosphofructo-2-kinase-fructose-2-6-bisphosphatase-2-inhibitors-ic50-ki.
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