 | Tacrine | IC50 | 250.0 [1] |
| Tacrine | Ki | 36.0 [1] |
 | Donepezil | IC50 | 16.0 [1] |
| Donepezil | Ki | 20.5 [1] |
 | Galantamine | IC50 | 1070.0 [1] |
| Galantamine | Ki | 61.9 [1], 61.96 [2], 250.0 [3], 300.0 [4] |
 | Physostigmine | IC50 | 40.0 [1] |
 | Rivastigmine | IC50 | 3030.0 [1] |
 | (1S,9R,13E)-1-Amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-one | IC50 | 47.0 [1] |
| (1S,9R,13E)-1-Amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-one | Ki | 47.0 [1] |
 | Propidium iodide | IC50 | 32300.0 [1] |
| Propidium iodide | Ki | 7140.0 [1] |
 | 4,4'-(3-Oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenylbenzenaminium) dibromide | IC50 | 18.0 [1], 30.0 [2] |
| 4,4'-(3-Oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenylbenzenaminium) dibromide | Ki | 10.0 [1] |
 | Eptastigmine | IC50 | 22.0 [1] |
 | Memoquin | IC50 | 1.55 [1] |
| Memoquin | Ki | 2.6 [1] |
 | Edrophonium chloride | IC50 | 200.0 [1], 500.0 [2], 5000.0 [3], 5170.0 [4] |
| Edrophonium chloride | Ki | 790.0 [1], 800.0 [2], 4800.0 [3] |
 | 7-Methoxy-1,2,3,4-tetrahydroacridin-9-amine | IC50 | 10500.0 [1] |
| 7-Methoxy-1,2,3,4-tetrahydroacridin-9-amine | Ki | 2090.0 [1], 6340.0 [2] |
 | 9-Amino-6-chloro-1,2,3,4-tetrahydro-acridine | IC50 | 9.9 [1] |
 | Caproctamine | IC50 | 169.82 [1] |
| Caproctamine | Ki | 0.1 [1], 104.0 [2] |
 | Neostigmine bromide | IC50 | 41.0 [1] |
 | Tacrine hydrochloride | IC50 | 205.0 [1] |
| Tacrine hydrochloride | Ki | 101.0 [1], 225.0 [2] |
 | 2H-1-Benzopyran-2-one, 6,7-dimethoxy-3-(4-((methyl(phenylmethyl)amino)methyl)phenyl)- | IC50 | 44.5 [1] |
| 2H-1-Benzopyran-2-one, 6,7-dimethoxy-3-(4-((methyl(phenylmethyl)amino)methyl)phenyl)- | Ki | 21.7 [1] |
 | (2-Chlorophenyl)methyl-[2-[[2-[2-[(2-chlorophenyl)methyl-dimethylazaniumyl]ethylamino]-2-oxoacetyl]amino]ethyl]-dimethylazanium | IC50 | 0.7 [1] |
| (2-Chlorophenyl)methyl-[2-[[2-[2-[(2-chlorophenyl)methyl-dimethylazaniumyl]ethylamino]-2-oxoacetyl]amino]ethyl]-dimethylazanium | Ki | 5.0 [1] |
 | Ethopropazine hydrochloride | IC50 | 1020000.0 [1] |
| Ethopropazine hydrochloride | Ki | 24700.0 [1], 25000.0 [2], 12100000.0 [3] |
 | Lipocrine | IC50 | 0.25 [1] |
 | Bis(7)-Tacrine | IC50 | 0.81 [1] |
 | [(8Bs)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-phenylcarbamate | IC50 | 24.0 [1], 349.95 [2], 350.0 [3] |
 | Xanthostigmine | IC50 | 0.3 [1] |
 | 3-(2-(1-Benzylpiperidin-4-yl)ethyl)benzo[d]isoxazole-6-carboxamide | IC50 | 8.79 [1] |
| 3-(2-(1-Benzylpiperidin-4-yl)ethyl)benzo[d]isoxazole-6-carboxamide | Ki | 8.71 [1] |
 | Acridine, 1,2,3,4-tetrahydro-9-amino-7-chloro- | IC50 | 550.0 [1] |
 | Pralidoxime chloride | IC50 | 366000.0 [1] |
 | Asoxime chloride | IC50 | 54000.0 [1], 66000.0 [2], 89000.0 [3], 203000.0 [4], 460000.0 [5] |
| Asoxime chloride | Ki | 25000.0 [1] |
 | Benzil | IC50 | 100000.0 [1] |
| Benzil | Ki | 100000.0 [1] |
 | Huprine Y | IC50 | 0.69 [1] |
 | 3-(2-(1-Benzylpiperidin-4-yl)ethyl)-6-methoxybenzo[d]isoxazole | IC50 | 8.3 [1], 8.32 [2], 8.8 [3] |
| 3-(2-(1-Benzylpiperidin-4-yl)ethyl)-6-methoxybenzo[d]isoxazole | Ki | 8.32 [1] |
 | 3-(2-(1-Benzylpiperidin-4-yl)ethyl)-6-bromobenzo[d]isoxazole | IC50 | 50.0 [1], 50.12 [2] |
| 3-(2-(1-Benzylpiperidin-4-yl)ethyl)-6-bromobenzo[d]isoxazole | Ki | 50.12 [1] |
 | N-[3-[2-(1-Benzylpiperidin-4-yl)ethyl]-1,2-benzoxazol-6-yl]acetamide | IC50 | 2.8 [1], 2.82 [2] |
| N-[3-[2-(1-Benzylpiperidin-4-yl)ethyl]-1,2-benzoxazol-6-yl]acetamide | Ki | 2.82 [1] |
 | 3-(2-(1-Benzylpiperidin-4-yl)ethyl)-7-methoxybenzo[d]isoxazole | IC50 | 7.08 [1], 7.1 [2] |
| 3-(2-(1-Benzylpiperidin-4-yl)ethyl)-7-methoxybenzo[d]isoxazole | Ki | 7.08 [1] |
 | 3-(2-(1-Benzylpiperidin-4-yl)ethyl)-5-methoxybenzo[d]isoxazole | IC50 | 7.19 [1], 7.2 [2], 7.24 [3] |
| 3-(2-(1-Benzylpiperidin-4-yl)ethyl)-5-methoxybenzo[d]isoxazole | Ki | 7.24 [1] |
 | 3-(2-(1-Benzylpiperidin-4-yl)ethyl)benzo[d]isoxazol-6-ol | IC50 | 25.7 [1], 26.0 [2] |
| 3-(2-(1-Benzylpiperidin-4-yl)ethyl)benzo[d]isoxazol-6-ol | Ki | 25.7 [1] |
 | N-{3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-benzo[d]isoxazol-6-yl}-benzamide | IC50 | 9.33 [1], 9.4 [2] |
| N-{3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-benzo[d]isoxazol-6-yl}-benzamide | Ki | 9.33 [1] |
 | 3-(2-(1-Benzylpiperidin-4-yl)ethyl)benzo[d]isoxazole | IC50 | 54.95 [1], 55.0 [2], 210.0 [3] |
| 3-(2-(1-Benzylpiperidin-4-yl)ethyl)benzo[d]isoxazole | Ki | 208.93 [1] |
 | 3-(2-(1-Benzylpiperidin-4-yl)ethyl)benzo[d]isoxazol-6-amine | IC50 | 19.95 [1], 20.0 [2] |
| 3-(2-(1-Benzylpiperidin-4-yl)ethyl)benzo[d]isoxazol-6-amine | Ki | 19.95 [1] |
 | 3-(2-(1-Benzylpiperidin-4-yl)ethyl)-5-methylbenzo[d]isoxazole | IC50 | 7.76 [1], 7.8 [2] |
| 3-(2-(1-Benzylpiperidin-4-yl)ethyl)-5-methylbenzo[d]isoxazole | Ki | 7.76 [1] |
 | Benzo[d]isoxazol-3-yl-(1-benzyl-piperidin-4-ylmethyl)-amine | IC50 | 319.89 [1], 320.0 [2], 323.59 [3] |
| Benzo[d]isoxazol-3-yl-(1-benzyl-piperidin-4-ylmethyl)-amine | Ki | 323.59 [1] |
 | 1-(2-(1-Benzylpiperidin-4-yl)ethyl)isoquinoline | IC50 | 218.78 [1], 219.79 [2], 220.0 [3] |
| 1-(2-(1-Benzylpiperidin-4-yl)ethyl)isoquinoline | Ki | 218.78 [1] |
 | 6-[Ethyl-[(2-methoxyphenyl)methyl]amino]-N-[8-[6-[ethyl-[(2-methoxyphenyl)methyl]amino]hexanoyl-methylamino]octyl]-N-methylhexanamide | IC50 | 16.1 [1], 16.22 [2], 17.38 [3], 18.62 [4] |
| 6-[Ethyl-[(2-methoxyphenyl)methyl]amino]-N-[8-[6-[ethyl-[(2-methoxyphenyl)methyl]amino]hexanoyl-methylamino]octyl]-N-methylhexanamide | Ki | 12.2 [1] |
 | 4-Amino-alpha-diethylamino-o-cresol dihydrochloride | IC50 | 17800.0 [1], 48300.0 [2] |
| 4-Amino-alpha-diethylamino-o-cresol dihydrochloride | Ki | 6300.0 [1], 16000.0 [2], 37400.0 [3], 37700.0 [4] |
 | Donepezil hydrochloride | IC50 | 11.6 [1], 20.0 [2], 32.0 [3], 120.0 [4] |
 | Obidoxime chloride | IC50 | 577000.0 [1], 870000.0 [2], 910000.0 [3], 2210000.0 [4] |
 | Profenamine | IC50 | 260.0 [1], 300.0 [2], 260000.0 [3] |
 | (1R)-7-Chloro-15-ethyl-10-azatetracyclo[11.3.1.02,11.04,9]heptadeca-2,4(9),5,7,10,14-hexaen-3-amine | IC50 | 0.32 [1], 1.1 [2] |
| (1R)-7-Chloro-15-ethyl-10-azatetracyclo[11.3.1.02,11.04,9]heptadeca-2,4(9),5,7,10,14-hexaen-3-amine | Ki | 0.03 [1], 0.67 [2] |
 | 3-(3-(1-Benzylpiperidin-4-yl)propyl)benzo[d]isoxazole | IC50 | 9.0 [1], 891.25 [2], 900.0 [3] |
| 3-(3-(1-Benzylpiperidin-4-yl)propyl)benzo[d]isoxazole | Ki | 891.25 [1] |
 | 7-Chloro-15-methyl-10-azatetracyclo[11.3.1.02,11.04,9]heptadeca-2,4(9),5,7,10,14-hexaen-3-amine;hydrochloride | IC50 | 0.69 [1], 0.78 [2], 1.07 [3] |
| 7-Chloro-15-methyl-10-azatetracyclo[11.3.1.02,11.04,9]heptadeca-2,4(9),5,7,10,14-hexaen-3-amine;hydrochloride | Ki | 0.03 [1] |
 | N-{3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-benzo[d]isoxazol-6-yl}-benzenesulfonamide | IC50 | 14.0 [1] |
| N-{3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-benzo[d]isoxazol-6-yl}-benzenesulfonamide | Ki | 14.13 [1] |
 | 3-[2-(1-Benzyl-4-piperidinyl)ethyl]-1,2-benzisothiazole | IC50 | 97.72 [1], 99.0 [2], 100.0 [3] |
| 3-[2-(1-Benzyl-4-piperidinyl)ethyl]-1,2-benzisothiazole | Ki | 100.0 [1] |
 | 3-(2-(1-Benzylpiperidin-4-yl)ethyl)benzo[d]isoxazole-6-carbonitrile | IC50 | 100.93 [1], 101.0 [2] |
| 3-(2-(1-Benzylpiperidin-4-yl)ethyl)benzo[d]isoxazole-6-carbonitrile | Ki | 100.0 [1] |
 | 3-(1-Benzyl-piperidin-4-ylmethoxy)-benzo[d]isoxazole | IC50 | 2570.4 [1], 2582.26 [2], 2600.0 [3] |
| 3-(1-Benzyl-piperidin-4-ylmethoxy)-benzo[d]isoxazole | Ki | 2570.4 [1] |
 | 3-[2-[(1-Phenylmethyl)-4-piperidyl]Ethylamino]-1,2-benzisoxazole | IC50 | 810.0 [1], 812.83 [2] |
| 3-[2-[(1-Phenylmethyl)-4-piperidyl]Ethylamino]-1,2-benzisoxazole | Ki | 812.83 [1] |
 | 3-(2-(1-Benzylpiperidin-4-yl)ethyl)-5,6-dihydroisoxazolo[4,5-g]quinolin-7(8H)-one | IC50 | 0.57 [1], 0.58 [2] |
| 3-(2-(1-Benzylpiperidin-4-yl)ethyl)-5,6-dihydroisoxazolo[4,5-g]quinolin-7(8H)-one | Ki | 0.58 [1] |
 | 3-(2-(1-Benzylpiperidin-4-yl)ethyl)-6H-isoxazolo[5,4-e]indol-7(8H)-one | IC50 | 3.6 [1], 3.63 [2] |
| 3-(2-(1-Benzylpiperidin-4-yl)ethyl)-6H-isoxazolo[5,4-e]indol-7(8H)-one | Ki | 3.63 [1] |
 | Ethyl 5-amino-4-(4-methoxyphenyl)-2-methyl-1,4,6,7,8,9-hexahydrobenzo[b][1,8]naphthyridine-3-carboxylate | IC50 | 45.0 [1], 105.0 [2], 110.0 [3] |
| Ethyl 5-amino-4-(4-methoxyphenyl)-2-methyl-1,4,6,7,8,9-hexahydrobenzo[b][1,8]naphthyridine-3-carboxylate | Ki | 109.0 [1] |
 | 3-(2-(1-Benzylpiperidin-4-yl)ethyl)-6-morpholinobenzo[d]isoxazole | IC50 | 0.8 [1] |
Calculator
