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Acidic mammalian chitinase Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(2-methylpropyl)piperidin-4-amineIC5014.2 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(2-methylpropyl)piperidin-4-amineKi13.5 [1]
5-{4-[2-(4-Bromophenoxy)ethyl]piperazin-1-Yl}-4h-1,2,4-Triazol-3-AmineIC50210.0 [1], 5450.0 [2]
AcetazolamideIC501000000.0 [1]
KinetinIC501000000.0 [1]
AllosamidinIC5040.0 [1]
8-ChlorotheophyllineIC502500000.0 [1]
ArgifinIC504500.0 [1]
2-[(3-Amino-4-methyl-6-phenylfuro[2,3-b]pyridin-2-yl)carbonyl]-N-methyl-1-hydrazinecarbothioamideIC5030000.0 [1]
2-Piperazin-1-ylnicotinamideIC50101700.0 [1]
2-Methyl-3-{[4-(Pyridin-2-Yl)piperazin-1-Yl]methyl}-1h-IndoleIC50700.0 [1]
1-[1-(5-Amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-3-(4-bromophenyl)ureaIC50100000.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[(4-bromophenyl)methyl]piperidine-4-carboxamideIC50100000.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-bromophenyl)ethyl]-N-ethylpiperidin-4-amineIC5073.0 [1]
N-[[1-(5-Amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]methyl]-4-bromobenzamideIC50100000.0 [1]
N-[1-(5-Amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-1-(4-bromophenyl)methanesulfonamideIC503325.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-benzyl-N-[2-(4-chlorophenyl)ethyl]piperidin-4-amineIC505.4 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-ethylpiperidin-4-amineIC50182.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-cyclopropylphenyl)ethyl]-N-methylpiperidin-4-amineIC501545.0 [1]
N-[1-(5-Amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-2-(4-bromophenyl)acetamideIC50100000.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-bromophenyl)ethyl]-N-(2-methylpropyl)piperidin-4-amineIC508.7 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(naphthalen-1-ylmethyl)piperidin-4-amineIC503.4 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-methyl-N-(2-phenylethyl)piperidin-4-amineIC5018450.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-bromophenyl)ethyl]-N-methylpiperidin-4-amineIC50348.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-methylpiperidin-4-amineIC50660.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-ethylphenyl)ethyl]-N-methylpiperidin-4-amineIC50970.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-tert-butylphenyl)ethyl]-N-methylpiperidin-4-amineIC5013200.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-methyl-N-[2-(4-methylphenyl)ethyl]piperidin-4-amineIC501111.0 [1]
3-[4-[[(4-Bromophenyl)methyl-methylamino]methyl]piperidin-1-yl]-1H-1,2,4-triazol-5-amineIC50100000.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-propan-2-ylpiperidin-4-amineIC50134.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-methyl-N-[2-(4-propan-2-ylphenyl)ethyl]piperidin-4-amineIC504137.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-[(2-chlorophenyl)methyl]piperidin-4-amineIC503.5 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(2,4-dichlorophenyl)ethyl]-N-methylpiperidin-4-amineIC502025.0 [1]
N-[1-(5-Amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-1-(4-bromophenyl)-N-methylmethanesulfonamideIC50100000.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(cyclohexylmethyl)piperidin-4-amineIC508.7 [1]
1-[4-(5-Amino-1H-1,2,4-triazol-3-yl)piperazin-1-yl]-2-(4-bromophenoxy)ethanoneIC5012250.0 [1]
1-[(E)-(3-Ethoxy-4-hydroxy-5-nitrophenyl)methylideneamino]-3-prop-2-enylthioureaIC50100000.0 [1]
1,2-Bis[(E)-furan-2-ylmethylideneamino]guanidineIC5015000.0 [1]
N-({4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}carbamothioyl)cyclopropanecarboxamideIC50100000.0 [1]
4-(4-Chlorophenyl)piperazine-1-carboximidamideIC5013000.0 [1]
N-[[4-[(5-Methyl-1,2-oxazol-3-yl)sulfamoyl]phenyl]carbamothioyl]prop-2-enamideIC5080000.0 [1]
N-Ethyl-2-(4-methylpiperazin-1-yl)pyridine-3-carboxamideIC5022000.0 [1]
N-[(Z)-3-(2-Carbamothioylhydrazinyl)-1-[4-(dimethylamino)phenyl]-3-oxoprop-1-en-2-yl]benzamideIC504000.0 [1]
N-[(2-Phenyl-1,3-benzoxazol-5-yl)carbamothioyl]propanamideIC5040000.0 [1]
Items per page: 1 - 10 of 44
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References

This online tool may be cited as follows

MLA

"Quest Database™ Acidic mammalian chitinase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/acidic-mammalian-chitinase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 10). Quest Database™ Acidic mammalian chitinase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/acidic-mammalian-chitinase-inhibitors-ic50-ki.
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