Name: ADAM17 Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

ADAM17 Inhibitors (IC50, Ki)

Structure	Compound Name	Standard Type	Standard Values (in nM)
	(2R)-N-Hydroxy-2-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]-3-methylbutanamide;hydrochloride	IC50	750.0 ^[1]
	[(R)-3-(Hydroxycarbamoyl)-3-[4-(2-butynyloxy)phenylsulfonylamino]propyl]carbamic acid benzyl ester	IC50	260.0 ^[1]
	(2R)-2-[(4-But-2-ynoxyphenyl)sulfonylamino]-4-(1,3-dioxoisoindol-2-yl)-N-hydroxybutanamide	IC50	280.0 ^[1]
	Benzyl N-[(4R)-4-[[4-[(3,5-dibromophenyl)methoxy]phenyl]sulfonylamino]-5-(hydroxyamino)-5-oxopentyl]carbamate	IC50	349.0 ^[1]
	Marimastat	IC50	3.8 ^[1], 4100.0 ^[2], 7000.0 ^[3], 10000.0 ^[4]
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References

This online resource may be cited as follows

MLA	"Quest Database™ ADAM17 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 7 Aug. 2026, https://www.aatbio.com/data-sets/adam17-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2026, August 7). Quest Database™ ADAM17 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/adam17-inhibitors-ic50-ki.
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