Name: ADAMTS5 Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

ADAMTS5 Inhibitors (IC50, Ki)

Structure	Compound Name	Standard Type	Standard Values (in nM)
	(2R,3R)-1-[4-[(2-Chloro-4-fluorophenyl)methoxy]phenyl]sulfonyl-N,3-dihydroxy-3-methylpiperidine-2-carboxamide	IC50	1.0 ^[1], 6.3 ^[2], 18.0 ^[3]
	(2R)-N-[[(4R)-4-Cyclopropyl-2,5-dioxoimidazolidin-4-yl]methyl]-2-[[4-(trifluoromethyl)phenyl]methyl]butanamide	IC50	2.0 ^[1], 20.0 ^[2]
	N-[[(4R)-4-Cyclopropyl-2,5-dioxoimidazolidin-4-yl]methyl]-2,2-dimethyl-3-[4-(trifluoromethyl)phenyl]propanamide	IC50	4.0 ^[1], 64.0 ^[2]
	(2S)-2-Cyclopropyl-N-[[(4R)-4-cyclopropyl-2,5-dioxoimidazolidin-4-yl]methyl]-3-[4-(trifluoromethyl)phenyl]propanamide	IC50	2.0 ^[1], 18.0 ^[2]
	(2S)-N-[[(4R)-4-Cyclopropyl-2,5-dioxoimidazolidin-4-yl]methyl]-3-methyl-2-[[4-(trifluoromethyl)phenyl]methyl]butanamide	IC50	8.0 ^[1], 150.0 ^[2]
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References

This online resource may be cited as follows

MLA	"Quest Database™ ADAMTS5 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 15 Dec. 2025, https://www.aatbio.com/data-sets/adamts5-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, December 15). Quest Database™ ADAMTS5 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/adamts5-inhibitors-ic50-ki.
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