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Alcohol dehydrogenase class III Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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3-(5-(4-(1H-Imidazol-1-yl)phenyl)-1-(4-carbamoyl-2-methylphenyl)-1H-pyrrol-2-yl)propanoic acidIC5020.0 [1]
4,4'-Bis(2H-tetrazole-5-yl)-1,1'-biphenylIC503279.0 [1]
4-(4-Imidazol-1-ylphenyl)-3-methylbenzoic acidIC5029.0 [1]
3-Fluoro-4-(5-imidazol-1-yl-3-methylpyridin-2-yl)benzoic acidIC5036.0 [1]
3-Ethyl-5-imidazol-1-yl-2-[4-(2H-tetrazol-5-yl)phenyl]pyridineIC5066.0 [1]
5-[4-(4-Imidazol-1-yl-2-methylphenyl)phenyl]-2H-tetrazoleIC5014.0 [1]
3-Chloro-4-(4-imidazol-1-ylphenyl)benzoic acidIC5030.0 [1]
5-[4-(4-Imidazol-1-ylphenyl)phenyl]-2H-tetrazoleIC5022.0 [1]
4-(3-Chloro-5-imidazol-1-ylpyridin-2-yl)benzoic acidIC5089.0 [1]
5-[3-Chloro-4-(4-imidazol-1-yl-2-methylphenyl)phenyl]-2H-tetrazoleIC5012.0 [1]
5-[3-Chloro-4-[4-(2-methylimidazol-1-yl)phenyl]phenyl]-2H-tetrazoleIC5037.0 [1]
5-[4-[4-(2-Methylimidazol-1-yl)phenyl]phenyl]-2H-tetrazoleIC5097.0 [1]
2-[2-Fluoro-4-(2H-tetrazol-5-yl)phenyl]-5-imidazol-1-yl-3-methylpyridineIC5014.0 [1]
5-Imidazol-1-yl-2-[2-methyl-4-(2H-tetrazol-5-yl)phenyl]pyridineIC5044.0 [1]
4-(5-Imidazol-1-yl-3-methylpyridin-2-yl)benzoic acidIC5041.0 [1]
4-(4-Imidazol-1-ylphenyl)benzoic acidIC5062.0 [1]
4-(4-Imidazol-1-yl-2-methylphenyl)benzoic acidIC5020.0 [1]
5-Imidazol-1-yl-3-methyl-2-[4-(2H-tetrazol-5-yl)phenyl]pyridineIC5017.0 [1]
3-Fluoro-4-(4-imidazol-1-ylphenyl)benzoic acidIC5029.0 [1]
3-Chloro-5-imidazol-1-yl-2-[4-(2H-tetrazol-5-yl)phenyl]pyridineIC5020.0 [1]
5-[4-(2-Ethyl-4-imidazol-1-ylphenyl)phenyl]-2H-tetrazoleIC506.1 [1]
4-(2-Chloro-4-imidazol-1-ylphenyl)benzoic acidIC5059.0 [1]
5-[3-Chloro-4-(4-imidazol-1-ylphenyl)phenyl]-2H-tetrazoleIC509.2 [1]
3-Ethyl-2-[2-fluoro-4-(2H-tetrazol-5-yl)phenyl]-5-imidazol-1-ylpyridineIC5062.0 [1]
5-[4-(2-Ethyl-4-imidazol-1-ylphenyl)-3-fluorophenyl]-2H-tetrazoleIC5011.0 [1]
5-[4-(2-Chloro-4-imidazol-1-ylphenyl)phenyl]-2H-tetrazoleIC5022.0 [1]
5-[4-(4-Imidazol-1-ylphenyl)-3-methylphenyl]-2H-tetrazoleIC5026.0 [1]
3-Chloro-2-[2-fluoro-4-(2H-tetrazol-5-yl)phenyl]-5-imidazol-1-ylpyridineIC5027.0 [1]
4-(5-Imidazol-1-ylpyridin-2-yl)benzoic acidIC50214.0 [1]
3-Chloro-5-imidazol-1-yl-2-[2-methyl-4-(2H-tetrazol-5-yl)phenyl]pyridineIC50935.0 [1]
5-[3-Fluoro-4-(4-imidazol-1-ylphenyl)phenyl]-2H-tetrazoleIC5020.0 [1]
5-[4-[2-Ethyl-4-(2-methylimidazol-1-yl)phenyl]phenyl]-2H-tetrazoleIC5024.0 [1]
2-[2-Chloro-4-(2H-tetrazol-5-yl)phenyl]-5-imidazol-1-ylpyridineIC50308.0 [1]
5-Imidazol-1-yl-2-[4-(2H-tetrazol-5-yl)phenyl]pyridineIC5032.0 [1]
4-(4-Imidazol-1-ylphenyl)-3-(trifluoromethyl)benzoic acidIC5038.0 [1]
3-Cyclohexyl-5-imidazol-1-yl-2-[4-(2H-tetrazol-5-yl)phenyl]pyridineIC5074.0 [1]
5-[3-Chloro-4-[4-(1,2,4-triazol-4-yl)phenyl]phenyl]-2H-tetrazoleIC50593.0 [1]
5-[4-(4-Imidazol-1-ylphenyl)-3-(trifluoromethyl)phenyl]-2H-tetrazoleIC5039.0 [1]
3-[4-(4-Imidazol-1-ylphenyl)phenyl]-4H-1,2,4-oxadiazol-5-oneIC50152.0 [1]
4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-6-pyridin-3-yl-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-2-oneIC501900.0 [1]
4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-6-(1-methylpyrazol-3-yl)-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-2-oneIC5035.0 [1]
(4S)-4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-5,6-diphenyl-3,4-dihydro-1H-pyrimidin-2-oneIC5011.0 [1]
4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-5,6-diphenyl-3,4-dihydropyrimidin-2(1H)-oneIC5029.0 [1]
4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-6-phenyl-5-(thiophen-3-yl)-3,4-dihydropyrimidin-2(1H)-oneIC5019.0 [1]
(4S)-4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-6-phenyl-5-thiophen-3-yl-3,4-dihydro-1H-pyrimidin-2-oneIC5018.0 [1]
(4R)-4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-5-phenyl-6-pyridin-3-yl-3,4-dihydro-1H-pyrimidin-2-oneIC506020.0 [1]
(4S)-4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-5-phenyl-6-pyridin-3-yl-3,4-dihydro-1H-pyrimidin-2-oneIC5028.0 [1]
4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-6-(1-methylpyrazol-3-yl)-5-thiophen-3-yl-3,4-dihydro-1H-pyrimidin-2-oneIC5040.0 [1]
4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-5-phenyl-6-(pyridin-3-yl)-3,4-dihydropyrimidin-2(1H)-oneIC5043.0 [1]
(4R)-4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-6-pyridin-3-yl-5-thiophen-3-yl-3,4-dihydro-1H-pyrimidin-2-oneIC501900.0 [1]
4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-6-pyridin-3-yl-5-thiophen-3-yl-3,4-dihydro-1H-pyrimidin-2-oneIC5024.0 [1]
(4R)-4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-5,6-diphenyl-3,4-dihydro-1H-pyrimidin-2-oneIC5019720.0 [1]
(4R)-4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-6-(1-methylpyrazol-3-yl)-5-thiophen-3-yl-3,4-dihydro-1H-pyrimidin-2-oneIC5031000.0 [1]
(4R)-4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-6-phenyl-5-thiophen-3-yl-3,4-dihydro-1H-pyrimidin-2-oneIC501820.0 [1]
(4S)-4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-6-(1-methylpyrazol-3-yl)-5-thiophen-3-yl-3,4-dihydro-1H-pyrimidin-2-oneIC5035.0 [1]
(4S)-4-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-6-pyridin-3-yl-5-thiophen-3-yl-3,4-dihydro-1H-pyrimidin-2-oneIC5016.0 [1]
6-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-4,5-diphenyl-5,6-dihydro-1H-pyrimidin-2-oneIC5029.0 [1]
6-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-4-phenyl-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-2-oneIC5019.0 [1]
6-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-5-phenyl-4-pyridin-3-yl-5,6-dihydro-1H-pyrimidin-2-oneIC5043.0 [1]
6-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-4-pyridin-3-yl-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-2-oneIC5024.0 [1]
6-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-4-(1-methylpyrazol-3-yl)-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-2-oneIC5040.0 [1]
3-Ethoxy-2-hydroxy-5-[(6S)-2-oxo-4-pyridin-3-yl-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-6-yl]benzoic acidIC503170.0 [1]
3-Ethoxy-2-hydroxy-5-[(6R)-2-oxo-4-pyridin-3-yl-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-6-yl]benzoic acidIC5067.0 [1]
3-Ethoxy-2-hydroxy-5-(2-oxo-4-pyridin-3-yl-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-6-yl)benzoic acidIC50150.0 [1]
3-Ethoxy-2-hydroxy-5-[4-(1-methylpyrazol-4-yl)-2-oxo-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-6-yl]benzoic acidIC5027.0 [1]
3-Ethoxy-2-hydroxy-5-[(6R)-4-(1-methylpyrazol-4-yl)-2-oxo-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-6-yl]benzoic acidIC5013.0 [1]
3-Ethoxy-2-hydroxy-5-[(6S)-4-(1-methylpyrazol-4-yl)-2-oxo-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-6-yl]benzoic acidIC50580.0 [1]
(6S)-6-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-4-(1-methylpyrazol-3-yl)-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-2-oneIC5031000.0 [1]
2-Hydroxy-4-[4-(1-methylpyrazol-3-yl)-2-oxo-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-6-yl]benzoic acidIC5039.0 [1]
2-Hydroxy-4-[(6S)-4-(1-methylpyrazol-4-yl)-2-oxo-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-6-yl]benzoic acidIC504250.0 [1]
2-Hydroxy-4-[(6R)-4-(1-methylpyrazol-4-yl)-2-oxo-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-6-yl]benzoic acidIC5023.0 [1]
(6R)-6-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-4,5-diphenyl-5,6-dihydro-1H-pyrimidin-2-oneIC5011.0 [1]
(6R)-6-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-4-phenyl-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-2-oneIC5018.0 [1]
(6S)-6-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-4-phenyl-5-thiophen-3-yl-5,6-dihydro-1H-pyrimidin-2-oneIC501820.0 [1]
(6R)-6-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-5-phenyl-4-pyridin-3-yl-5,6-dihydro-1H-pyrimidin-2-oneIC5028.0 [1]
(6S)-6-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-5-phenyl-4-pyridin-3-yl-5,6-dihydro-1H-pyrimidin-2-oneIC506020.0 [1]
(6S)-6-(3-Ethoxy-4-hydroxy-5-nitrophenyl)-4,5-diphenyl-5,6-dihydro-1H-pyrimidin-2-oneIC5019720.0 [1]
3-Ethoxy-2-hydroxy-5-(2-oxo-6-pyridin-3-yl-5-thiophen-3-yl-1,3-diazinan-4-yl)benzoic acidIC50150.0 [1]
3-Ethoxy-2-hydroxy-5-[(4R)-2-oxo-6-pyridin-3-yl-5-thiophen-3-yl-1,3-diazinan-4-yl]benzoic acidIC5067.0 [1]
3-Ethoxy-2-hydroxy-5-[(4S)-2-oxo-6-pyridin-3-yl-5-thiophen-3-yl-1,3-diazinan-4-yl]benzoic acidIC503170.0 [1]
3-Ethoxy-2-hydroxy-5-[6-(1-methylpyrazol-4-yl)-2-oxo-5-thiophen-3-yl-1,3-diazinan-4-yl]benzoic acidIC50580.0 [1]
2-Hydroxy-4-[6-(1-methylpyrazol-4-yl)-2-oxo-5-thiophen-3-yl-1,3-diazinan-4-yl]benzoic acidIC504250.0 [1]
Items per page: 1 - 10 of 82
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References

This online tool may be cited as follows

MLA

"Quest Database™ Alcohol dehydrogenase class III Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/alcohol-dehydrogenase-class-iii-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 8). Quest Database™ Alcohol dehydrogenase class III Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/alcohol-dehydrogenase-class-iii-inhibitors-ic50-ki.
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