Aldehyde dehydrogenase dimeric NADP-preferring Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	1-[(4-Fluorophenyl)sulfonyl]-2-methyl-1H-benzimidazole	IC50	200.0 [1]
	1-[(4-Fluorophenyl)sulfonyl]-2-methyl-1H-benzimidazole	Ki	82.0 [1], 110.0 [2], 200.0 [3]
	1-Benzyl-1H-indole-2,3-dione	IC50	7700.0 [1]
	1-Benzyl-1H-indole-2,3-dione	Ki	1200.0 [1], 4000.0 [2]
	7-Bromo-5-methyl-1H-indole-2,3-dione	IC50	360.0 [1]
	7-Bromo-5-methyl-1H-indole-2,3-dione	Ki	380.0 [1], 500.0 [2]
	1-(Toluene-4-sulfonyl)-1H-benzoimidazole	IC50	50000.0 [1]
	1-(4-Chloro-benzenesulfonyl)-1H-benzoimidazole	IC50	1500.0 [1]
	1-(4-Chlorophenyl)sulfonyl-2-benzimidazolamine	IC50	1200.0 [1]
	N-[4-(Benzoimidazole-1-sulfonyl)-phenyl]-acetamide	IC50	100000.0 [1]
	1-[(4-Methoxy-3-methylphenyl)sulfonyl]-2-methyl-1H-benzimidazole	IC50	2000.0 [1]
	2-Methyl-1-(4-methylphenyl)sulfonylbenzimidazole	IC50	700.0 [1]
	1-(4-Fluoro-2-methoxy-benzenesulfonyl)-2-methyl-1H-benzoimidazole	IC50	100000.0 [1]
	1-(4-Chlorophenylsulfonyl)-2-acetyl-1H-benzoimidazole	IC50	1000.0 [1]
	2-Benzyl-1-[(4-chlorophenyl)sulfonyl]-1H-benzimidazole	IC50	100000.0 [1]
	1-(4-Fluorophenylsulfonyl)-1H-benzoimidazole	IC50	2100.0 [1]
	1-[(4-Fluorophenyl)sulfonyl]-5,6-dimethyl-1H-benzimidazole	IC50	100000.0 [1]
	1-((4-Fluoro-3-methoxyphenyl)sulfonyl)-2-methyl-1H-benzo[d]imidazole	IC50	900.0 [1]
	1-(Phenylsulfonyl)-1H-benzimidazole	IC50	50000.0 [1]
	1-[(4-Methoxyphenyl)sulfonyl]-5-nitro-1H-benzimidazole	IC50	100000.0 [1]
	4-Chloro-1-[(2-methylbenzimidazolyl)sulfonyl]benzene	IC50	300.0 [1]
	1-(2-Bromo-4-chlorophenyl)sulfonyl-2-methylbenzimidazole	IC50	100000.0 [1]
	1-[(3,4-Difluorophenyl)sulfonyl]-1H-benzimidazole	IC50	4200.0 [1]
	1H-1,3-Benzimidazol-1-yl (4-isobutylphenyl) sulfone	IC50	100000.0 [1]
	1-(4-Fluoro-2-methoxy-benzenesulfonyl)-1H-benzoimidazole	IC50	100000.0 [1]
	1-[(4-Chloro-3-methylphenyl)sulfonyl]-2-methyl-1H-benzimidazole	IC50	700.0 [1]
	1-Chloro-2-methoxy-4-[(2-methylbenzimidazolyl)sulfonyl]benzene	IC50	900.0 [1]
	N-{4-[(2-Methyl-1H-benzimidazol-1-yl)sulfonyl]phenyl}acetamide	IC50	100000.0 [1]
	1-[(2E)-3-Phenylprop-2-en-1-yl]-1H-indole-2,3-dione	IC50	310.0 [1]
	1-(3-Phenylpropyl)indole-2,3-dione	IC50	460.0 [1]
	1-Morpholin-4-ylmethyl-1H-indole-2,3-dione	IC50	1300.0 [1]
	N-(1-Hydroxy-2-oxo-2-thien-2-ylethyl)nicotinamide	IC50	10200.0 [1]
	1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-(morpholin-4-yl)propan-1-one	IC50	11700.0 [1]
	Ethyl {3-hydroxy-2-oxo-3-[2-oxo-2-(pyridin-2-yl)ethyl]-2,3-dihydro-1H-indol-1-yl}acetate	IC50	25500.0 [1]
	1-Pentyl-1H-indole-2,3-dione	IC50	420.0 [1]
	1-{[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]methyl}-1H-indole-2,3-dione	IC50	300.0 [1]
	1-[(4-Methylpiperazin-1-yl)methyl]-1H-indole-2,3-dione	IC50	1600.0 [1]
	1-{[4-(1,3-Benzodioxol-5-ylmethyl)piperazino]methyl}-5-bromo-1H-indole-2,3-dione	IC50	73000.0 [1]
	1-[[3-[(2,3-Dioxoindol-1-yl)methyl]imidazolidin-1-yl]methyl]indole-2,3-dione	IC50	1600.0 [1]
	5-Chloro-1-(2-phenylethyl)-1H-indole-2,3-dione	IC50	11000.0 [1]
	1-Benzyl-5-chloro-1H-indole-2,3-dione	IC50	16000.0 [1]
	N-(1-Hydroxy-2-oxo-2-thiophen-2-ylethyl)-4-methylbenzenesulfonamide	IC50	3400.0 [1]
	N-(1-Hydroxy-2-oxo-2-thiophen-2-ylethyl)pyridine-4-carboxamide	IC50	5600.0 [1]
	Indole-2,3-dione, 1-benzyl-5-bromo-	IC50	69000.0 [1]
	1-[(4-Chlorophenyl)sulfonyl]-2-cyclohexyl-1H-benzimidazole	IC50	100000.0 [1]
	2-{[7-(2-Fluorobenzyl)-1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl]sulfanyl}acetamide	IC50	100000.0 [1]
	6-Methyl-3,4-dihydro-2H,8H-pyrano[3,2-g]chromene-2,8-dione	IC50	5400.0 [1]
	1-{[4-(2-Fluorobenzyl)piperazin-1-yl]methyl}-1H-indole-2,3-dione	IC50	1800.0 [1]
	1-{[4-(3-Fluorobenzyl)piperazin-1-yl]methyl}-1H-indole-2,3-dione	IC50	1900.0 [1]
	1-{[4-(3-Methoxybenzyl)piperazin-1-yl]methyl}-1H-indole-2,3-dione	IC50	1200.0 [1]
	1-(2-Phenylethyl)-1H-indole-2,3-dione	IC50	450.0 [1]
	1-(4-Benzyl-piperazin-1-ylmethyl)-1H-indole-2,3-dione	IC50	930.0 [1]
	1-{[4-(4-Fluorobenzyl)piperazin-1-yl]methyl}-1H-indole-2,3-dione	IC50	1500.0 [1]
	4-(4-Chlorophenoxy)butyl thiocyanate	IC50	3700.0 [1]
	5-Bromo-1-(2-phenylethyl)-1H-indole-2,3-dione	IC50	18000.0 [1]
	5-Chloro-1-[(E)-3-phenylprop-2-enyl]indole-2,3-dione	IC50	100000.0 [1]
	2-Phenyl-1,10b-dihydrospiro[benzo[e]pyrazolo[1,5-c][1,3]oxazine-5,3'-indolin]-2'-one	IC50	38500.0 [1]
	N-(4-{[4-(Methylsulfonyl)-2-nitrophenyl]amino}phenyl)acetamide	IC50	16000.0 [1]
	3,4-Difluoro-N-[(2-nitrophenyl)methyl]aniline	IC50	5200.0 [1]
	1-{[4-(3-Chlorobenzyl)piperazin-1-yl]methyl}-1H-indole-2,3-dione	IC50	1700.0 [1]
	(4-Methoxyphenyl)[3-(propylthio)-6,7-dihydro[1,2,4]triazino[5,6-d][3,1]benzoxazepin-6-yl]methanone	IC50	2500.0 [1]
	3-Nitro-N-propan-2-yl-4-[3-(propan-2-ylamino)anilino]benzenesulfonamide	IC50	26300.0 [1]
	1-(4-Chlorophenyl)sulfonyl-2-piperidin-1-ylbenzimidazole	IC50	100000.0 [1]
	4-{[4-(Difluoromethoxy)phenyl]amino}-N-methyl-3-nitrobenzene-1-sulfonamide	IC50	24700.0 [1]
	2-[4-[2-Nitro-4-(propan-2-ylsulfamoyl)anilino]piperidin-1-yl]-N-phenylacetamide	IC50	25600.0 [1]
	3-Methyl-N-(4-{[4-(methylsulfamoyl)-2-nitrophenyl]amino}phenyl)butanamide	IC50	42300.0 [1]
	N-{4-[(4-Methanesulfonyl-2-nitrophenyl)amino]phenyl}-2-methylpropanamide	IC50	19600.0 [1]
	N-[4-[4-(Diethylsulfamoyl)-2-nitroanilino]phenyl]-2-methylpropanamide	IC50	100000.0 [1]
	[3-(Ethylthio)-6,7-dihydro[1,2,4]triazino[5,6-d][3,1]benzoxazepin-6-yl](4-methoxyphenyl)methanone	IC50	1500.0 [1]
	Ethyl {3-hydroxy-2-oxo-3-[2-oxo-2-(pyridin-4-yl)ethyl]-2,3-dihydro-1H-indol-1-yl}acetate	IC50	6300.0 [1]
	5-Acetyl-2-[2-(4-bromophenyl)-2-oxoethyl]sulfanyl-6-methyl-4-propyl-1,4-dihydropyridine-3-carbonitrile	IC50	71500.0 [1]
	4-(2,3-Dihydro-1H-inden-5-ylamino)-3-nitro-N-propan-2-ylbenzenesulfonamide	IC50	30500.0 [1]
	4-N,4-N-Dimethyl-1-N-[2-nitro-4-(trifluoromethylsulfonyl)phenyl]benzene-1,4-diamine	IC50	17000.0 [1]
	2-{4-[(2,5-Dichlorophenyl)sulfonyl]piperazin-1-yl}-1-(3-methylphenyl)ethanone	IC50	41000.0 [1]
	4-N-[2,4-Bis(methylsulfonyl)phenyl]-1-N-(cyclopentylmethyl)benzene-1,4-diamine	IC50	40000.0 [1]
	4-(4-Methoxyanilino)-N-methyl-3-nitrobenzenesulfonamide	IC50	31700.0 [1]
	N-(3-Ethyl-4-(3-fluoro-4-methoxyphenyl)-1,3-thiazol-2(3H)-ylidene)-N-phenylamine	IC50	60000.0 [1]
	N-(4-Methanesulfonyl-2-nitrophenyl)-2,3-dihydro-1H-inden-5-amine	IC50	26900.0 [1]
	3-Fluoro-N-(4-methanesulfonyl-2-nitrophenyl)-4-methylaniline	IC50	10800.0 [1]
	1-(1,3-Benzodioxol-5-yl)-3-(diethylamino)propan-1-one	IC50	3200.0 [1]
	4-[(4-Fluorophenyl)amino]-N-methyl-3-nitrobenzene-1-sulfonamide	IC50	26000.0 [1]
	N-[4-[2-Nitro-4-(trifluoromethylsulfonyl)phenoxy]phenyl]acetamide	IC50	100000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 82 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Aldehyde dehydrogenase dimeric NADP-preferring Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/aldehyde-dehydrogenase-dimeric-nadp-preferring-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Aldehyde dehydrogenase dimeric NADP-preferring Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/aldehyde-dehydrogenase-dimeric-nadp-preferring-inhibitors-ic50-ki.
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