Aldo-keto reductase family 1 member B10 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	2-Methoxy-4-hydroxycinnamic acid 3-(3-hydroxyphenyl)propyl ester	IC50	6.2 [1], 300.0 [2]
	2-Methoxy-4-hydroxycinnamic acid 3-(3-hydroxyphenyl)propyl ester	Ki	5.8 [1]
	Oleanolic acid	IC50	90.0 [1], 4000.0 [2]
	Oleanolic acid	Ki	72.0 [1], 160.0 [2], 660.0 [3], 940.0 [4], 3560.0 [5]
	Ursolic acid	IC50	4000.0 [1]
	Ursolic acid	Ki	2000.0 [1], 2100.0 [2], 2800.0 [3], 3700.0 [4], 6000.0 [5]
	N-Benzyl-7-hydroxy-2-(4-methoxyphenyl)iminochromene-3-carboxamide	IC50	4.7 [1]
	N-Benzyl-7-hydroxy-2-(4-methoxyphenyl)iminochromene-3-carboxamide	Ki	1.3 [1], 3.8 [2], 51.0 [3]
	Tolrestat	IC50	11.6 [1], 54.0 [2]
	Tolrestat	Ki	50.0 [1]
	Apigenin	IC50	6600.0 [1], 37100.0 [2]
	Apigenin	Ki	6000.0 [1]
	Flufenamic acid	IC50	760.0 [1], 96000.0 [2]
	(2Z)-7-Hydroxy-2-[(4-methoxyphenyl)imino]-N-(pyridin-2-yl)-2H-chromene-3-carboxamide	IC50	6.0 [1]
	(2Z)-7-Hydroxy-2-[(4-methoxyphenyl)imino]-N-(pyridin-2-yl)-2H-chromene-3-carboxamide	Ki	2.7 [1]
	Luteolin	IC50	9200.0 [1], 107800.0 [2]
	Isolithocholic acid	IC50	27.0 [1]
	Isolithocholic acid	Ki	15.0 [1]
	Caffeic acid phenethyl ester	IC50	80.0 [1]
	Caffeic acid phenethyl ester	Ki	46.0 [1]
	Epalrestat	IC50	330.0 [1]
	7-Hydroxyflavone	IC50	8300.0 [1], 160000.0 [2]
	Zopolrestat	IC50	620.0 [1], 2360.0 [2]
	3-((4-(Trifluoromethyl)Phenyl)Amino)Benzoic Acid	IC50	50000.0 [1]
	(2Z)-2-[(2,5-Dimethoxyphenyl)imino]-7-hydroxy-N-(pyridin-2-yl)-2H-chromene-3-carboxamide	IC50	22.0 [1]
	(2Z)-2-[(2,5-Dimethoxyphenyl)imino]-7-hydroxy-N-(pyridin-2-yl)-2H-chromene-3-carboxamide	Ki	16.0 [1]
	3-[(4-Nitrophenyl)amino]benzoic Acid	IC50	46000.0 [1]
	3-(4-Acetylanilino)benzoic acid	IC50	37100.0 [1]
	3-[(4-Bromophenyl)Amino]Benzoic Acid	IC50	50000.0 [1]
	3-(4-Tert-butylanilino)benzoic acid	IC50	15000.0 [1]
	(2Z)-2-[(3,4-Dimethoxyphenyl)imino]-7-hydroxy-N-(6-methylpyridin-2-yl)-2H-chromene-3-carboxamide	IC50	36.0 [1]
	(2Z)-2-[(3,4-Dimethoxyphenyl)imino]-7-hydroxy-N-(6-methylpyridin-2-yl)-2H-chromene-3-carboxamide	Ki	24.0 [1]
	(2Z)-2-[(2,4-Dimethoxyphenyl)imino]-7-hydroxy-N-(pyridin-2-yl)-2H-chromene-3-carboxamide	IC50	15.0 [1]
	(2Z)-2-[(2,4-Dimethoxyphenyl)imino]-7-hydroxy-N-(pyridin-2-yl)-2H-chromene-3-carboxamide	Ki	12.0 [1]
	7-Hydroxy-N-[3-(4-hydroxyphenyl)propyl]-2-oxochromene-3-carboxamide	IC50	4.2 [1]
	7-Hydroxy-N-[3-(4-hydroxyphenyl)propyl]-2-oxochromene-3-carboxamide	Ki	2.3 [1]
	Diclofenac	IC50	1900.0 [1]
	Daidzein	IC50	32200.0 [1]
	Enoxolone	IC50	4900.0 [1]
	Chlorogenic acid	IC50	7900.0 [1]
	Caffeic acid	IC50	90000.0 [1]
	Mefenamic acid	IC50	1600.0 [1]
	Betulinic acid	IC50	2000.0 [1]
	4-Hydroxycinnamic acid	IC50	63000.0 [1]
	Sorbinil	IC50	9600.0 [1]
	Biochanin A	IC50	36100.0 [1]
	Maslinic acid	IC50	630.0 [1]
	Asiatic acid	IC50	5900.0 [1]
	Bisdemethoxycurcumin	IC50	60.0 [1]
	3,5-Dicaffeoylquinic acid	IC50	130.0 [1]
	Artepillin C	IC50	53000.0 [1]
	3,4-Dicaffeoylquinic acid	IC50	240.0 [1]
	Erythrodiol	IC50	30000.0 [1]
	Benzyl caffeate	IC50	210.0 [1]
	Minalrestat	IC50	740.0 [1]
	(E)-3-(4-Hydroxy-3-(3-methyl-2-butenyl)phenyl)-2-propenoic acid	IC50	49000.0 [1]
	Phenethyl cinnamate	IC50	18000.0 [1]
	(3-Thioxo-2,3-Dihydro-5h-[1,2,4]triazino[5,6-B]indol-5-Yl)acetic Acid	IC50	21400.0 [1]
	(E)-Benzyl 3-(4-hydroxyphenyl)acrylate	IC50	130.0 [1]
	Isopropyl p-hydroxycinnamate	IC50	920.0 [1]
	7-Hydroxy-N-[2-(4-hydroxyphenyl)ethyl]-2-oxochromene-3-carboxamide	IC50	20.0 [1]
	4-Hydroxycinnamic acid phenethyl ester	IC50	69.0 [1]
	2-Benzyl-9-(carboxymethyl)-1-sulfanylidene-3,4-dihydropyrido[3,4-b]indole-6-carboxylic acid	IC50	40000.0 [1]
	N-[3-(4-Hydroxyphenyl)propyl]-2-oxochromene-3-carboxamide	IC50	2700.0 [1]
	3-Hydroxycinnamic acid phenethyl ester	IC50	19000.0 [1]
	2-(2-(Ethoxycarbonyl)-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic acid	IC50	9434.0 [1]
	{5-Chloro-2-[(Pentabromobenzyl)carbamoyl]phenoxy}acetic Acid	IC50	80.0 [1]
	(3S,5R,6R,8S,9S,10R,13S,14S)-10-(Hydroxymethyl)-13-methyl-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,5,6-triol	IC50	830.0 [1]
	(2Z)-7-Hydroxy-2-(phenylimino)-N-(pyridin-2-yl)-2H-chromene-3-carboxamide	IC50	12.0 [1]
	(2Z)-7-Hydroxy-2-[(4-methylphenyl)imino]-N-(pyridin-2-yl)-2H-chromene-3-carboxamide	IC50	8.6 [1]
	7-Hydroxy-2-(4-methoxyphenyl)imino-N-(2-methylpropyl)chromene-3-carboxamide	IC50	16.0 [1]
	2-(4-Bromophenyl)imino-7-hydroxy-N-pyridin-2-ylchromene-3-carboxamide	IC50	14.0 [1]
	7-Hydroxy-2-(4-hydroxyphenyl)imino-N-pyridin-2-ylchromene-3-carboxamide	IC50	6.8 [1]
	4-[[7-Hydroxy-3-(pyridin-2-ylcarbamoyl)chromen-2-ylidene]amino]benzoic acid	IC50	7.6 [1]
	7-Hydroxy-2-(4-iodophenyl)imino-N-pyridin-2-ylchromene-3-carboxamide	IC50	13.0 [1]
	2-[4-[[7-Hydroxy-3-(pyridin-2-ylcarbamoyl)chromen-2-ylidene]amino]phenyl]acetic acid	IC50	13.0 [1]
	7-Hydroxy-2-(4-methoxyphenyl)imino-N-propan-2-ylchromene-3-carboxamide	IC50	9.7 [1]
	N-Butyl-7-hydroxy-2-(4-methoxyphenyl)iminochromene-3-carboxamide	IC50	18.0 [1]
	N-Cyclohexyl-7-hydroxy-2-(4-methoxyphenyl)iminochromene-3-carboxamide	IC50	11.0 [1]
	7-Hydroxy-N-(2-hydroxyethyl)-2-(4-methoxyphenyl)iminochromene-3-carboxamide	IC50	11.0 [1]
	7-Hydroxy-N-(3-hydroxypropyl)-2-(4-methoxyphenyl)iminochromene-3-carboxamide	IC50	8.8 [1]
	5-Hydroxy-2-(4-methoxyphenyl)imino-N-pyridin-2-ylchromene-3-carboxamide	IC50	290.0 [1]
	2-[9-Fluoro-5-(4-methoxyphenyl)-3-methyl-1-oxopyrimido[4,5-c]quinolin-2-yl]acetic acid	IC50	10000.0 [1]
	2-[5-(4-Chlorophenyl)-3-methyl-1-oxopyrimido[4,5-c]quinolin-2-yl]acetic acid	IC50	7860.0 [1]
	N-[3-(3,5-Difluorophenyl)propyl]-7-hydroxy-2-oxochromene-3-carboxamide	IC50	7.8 [1]
	N-[3-(3-Fluorophenyl)propyl]-7-hydroxy-2-oxochromene-3-carboxamide	IC50	6.0 [1]
	7-Hydroxy-N-[3-(4-methylphenyl)propyl]-2-oxochromene-3-carboxamide	IC50	7.0 [1]
	7-Hydroxy-N-[4-(4-hydroxyphenyl)butyl]-2-oxochromene-3-carboxamide	IC50	11.0 [1]
	7-Hydroxy-N-[3-(3-hydroxyphenyl)propyl]-2-oxochromene-3-carboxamide	IC50	8.3 [1]
	7-Hydroxy-N-[3-(3-hydroxyphenyl)propyl]-2-(4-methoxyphenyl)iminochromene-3-carboxamide	IC50	7.5 [1]
	N-[3-(4-Fluorophenyl)propyl]-7-hydroxy-2-oxochromene-3-carboxamide	IC50	3.5 [1]
	8-Hydroxy-N-[3-(4-hydroxyphenyl)propyl]-2-oxochromene-3-carboxamide	IC50	1500.0 [1]
	7-Hydroxy-N-[3-(4-methoxyphenyl)propyl]-2-oxochromene-3-carboxamide	IC50	11.0 [1]
	7-Hydroxy-N-[3-(2-hydroxyphenyl)propyl]-2-oxochromene-3-carboxamide	IC50	6.4 [1]
	2-[3-Benzyl-5-(4-chlorophenyl)-1-oxopyrimido[4,5-c]quinolin-2-yl]acetic acid	IC50	2350.0 [1]
	2-[5-(4-Bromophenyl)-9-fluoro-3-methyl-1-oxopyrimido[4,5-c]quinolin-2-yl]acetic acid	IC50	9610.0 [1]
	2-[5-(4-Chlorophenyl)-1-oxo-3-propylpyrimido[4,5-c]quinolin-2-yl]acetic acid	IC50	3330.0 [1]
	2-[9-Bromo-5-(4-bromophenyl)-3-methyl-1-oxopyrimido[4,5-c]quinolin-2-yl]acetic acid	IC50	16320.0 [1]
	2-[5-(4-Chlorophenyl)-3-ethyl-9-fluoro-1-oxopyrimido[4,5-c]quinolin-2-yl]acetic acid	IC50	3890.0 [1]
	2-[5-(4-Bromophenyl)-3-methyl-1-oxopyrimido[4,5-c]quinolin-2-yl]acetic acid	IC50	10000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Aldo-keto reductase family 1 member B10 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/aldo-keto-reductase-family-1-member-b10-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 8). Quest Database™ Aldo-keto reductase family 1 member B10 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/aldo-keto-reductase-family-1-member-b10-inhibitors-ic50-ki.
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