Aldo-keto reductase family 1 member C2 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Flufenamic acid	IC50	530.0 [1]
	Indomethacin	IC50	36530.0 [1], 75000.0 [2], 100000.0 [3]
	Indomethacin	Ki	100000.0 [1]
	N-Phenylanthranilic acid	IC50	440.0 [1]
	4-(Phenylamino)benzoic acid	IC50	3000.0 [1]
	3-((4-(Trifluoromethyl)Phenyl)Amino)Benzoic Acid	IC50	15000.0 [1], 15400.0 [2]
	3-[(4-Nitrophenyl)amino]benzoic Acid	IC50	3380.0 [1], 3400.0 [2]
	3-(4-Acetylanilino)benzoic acid	IC50	19000.0 [1], 19500.0 [2]
	3-((4-Methoxyphenyl)amino)benzoic acid	IC50	11000.0 [1], 11500.0 [2]
	3-(Phenylamino)benzoic acid	IC50	12900.0 [1], 13000.0 [2]
	3-[(4-Bromophenyl)Amino]Benzoic Acid	IC50	18000.0 [1], 18100.0 [2]
	3-(4-Tert-butylanilino)benzoic acid	IC50	31000.0 [1], 31100.0 [2]
	3-[(4-Methylphenyl)Amino]Benzoic Acid	IC50	56000.0 [1], 56200.0 [2]
	3-[(4-Chlorophenyl)Amino]Benzoic Acid	IC50	19000.0 [1], 19100.0 [2]
	Medroxyprogesterone acetate	IC50	1600.0 [1], 4100.0 [2]
	Jasmonic acid	Ki	15000.0 [1], 18000.0 [2]
	Mefenamic acid	IC50	6970.0 [1]
	Mefenamic acid	Ki	220.0 [1]
	Meclofenamic acid	IC50	8740.0 [1]
	3,5-Dichlorosalicylic acid	Ki	70.0 [1]
	5-Bromo-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid	Ki	87.0 [1]
	1-(4-Chlorobenzoyl)-5-methoxy-1H-indole-3-acetic acid	IC50	100.0 [1], 100000.0 [2]
	1-[4-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)phenyl]pyrrolidin-2-one	IC50	30000.0 [1]
	3-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]propanoic acid	IC50	57.0 [1], 56530.0 [2]
	2-[5-Methoxy-2-methyl-1-(4-methylbenzoyl)indol-3-yl]acetic acid	IC50	54.5 [1], 54500.0 [2]
	5-Hydroxy-3-[(4-methoxyphenyl)methyl]-N-[3-(trifluoromethyl)phenyl]triazole-4-carboxamide	IC50	73230.0 [1]
	9-(4-Chlorobenzoyl)-6-methoxy-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid	IC50	53.5 [1], 53650.0 [2]
	3a-Phenyl-3,4-dihydro-2H-pyrrolo[1,2-a]benzimidazol-1-one	IC50	92300.0 [1]
	3a-Phenyl-3,4-dihydro-2H-pyrrolo[1,2-a]benzimidazol-1-one	Ki	46200.0 [1]
	2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-(trifluoromethylsulfonyl)acetamide	IC50	81.0 [1], 80950.0 [2]
	1h-Indole-3-acetic acid,5-methoxy-2-methyl-1-[4-(trifluoromethyl)benzoyl]-	IC50	35.73 [1], 35730.0 [2]
	2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(2-hydroxyphenyl)acetamide	IC50	205700.0 [1]
	2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(2-hydroxyphenyl)acetamide	Ki	102800.0 [1]
	3-[1-(4-Chlorobenzoyl)-5-methoxy-3-methylindol-2-yl]propanoic acid	IC50	14.5 [1], 14450.0 [2]
	3-[1-(4-Chlorobenzoyl)-5-methoxy-3-methylindol-2-yl]-N-methylsulfonylpropanamide	IC50	93.0 [1], 93000.0 [2]
	3-[1-(4-Chlorobenzoyl)-3-ethyl-5-methoxyindol-2-yl]propanoic acid	IC50	49.57 [1], 49570.0 [2]
	2-[1-(4-Chlorobenzoyl)-5-methoxyindol-3-yl]-N-(trifluoromethylsulfonyl)acetamide	IC50	50.13 [1], 50130.0 [2]
	1-[4-(Chloromethyl)benzoyl]-2-methyl-5-methoxy-1H-indole-3-acetic acid	IC50	40.74 [1], 40740.0 [2]
	Diazepam	IC50	2400.0 [1]
	Naproxen	IC50	31300.0 [1]
	Flurbiprofen	IC50	32500.0 [1]
	Caffeic acid phenethyl ester	IC50	6000.0 [1]
	Dexibuprofen	IC50	42400.0 [1]
	5-Methoxy-2-methyl-3-indoleacetic acid	IC50	100000.0 [1]
	Cloxazolam	Ki	10000.0 [1]
	2'-Hydroxyflavone	IC50	47100.0 [1]
	3,5-Dibromosalicylic acid	Ki	82.0 [1]
	(E)-3-(4-Hydroxy-3-(3-methyl-2-butenyl)phenyl)-2-propenoic acid	IC50	108000.0 [1]
	3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic acid	IC50	30000.0 [1]
	2-((4-Methoxyphenyl)amino)benzoic acid	IC50	700.0 [1]
	1-[4-(Piperidine-1-sulfonyl)-phenyl]-pyrrolidin-2-one	IC50	30000.0 [1]
	N-[(2,6-Dioxo-4-phenylcyclohexylidene)methyl]glycine	Ki	18200.0 [1]
	3-[(2-Naphthylsulfonyl)amino]propanoic acid	Ki	57300.0 [1]
	Morpholin-4-yl-(4-phenyl-piperazin-1-yl)-methanone	IC50	30000.0 [1]
	Anthranilic acid, N-(3-methoxyphenyl)-	IC50	1110.0 [1]
	Anthranilic acid, N-p-nitrophenyl-	IC50	280.0 [1]
	3-[(2-Phenylethyl)sulfamoyl]benzoic acid	IC50	30000.0 [1]
	3-(1,3-Dihydro-isoindole-2-sulfonyl)-benzoic acid	IC50	30000.0 [1]
	4-[Methyl(phenylsulfonyl)amino]benzoic acid	Ki	119000.0 [1]
	4-((3,4-Dihydroisoquinolin-2(1H)-yl)sulfonyl)benzoic acid	IC50	30000.0 [1]
	4-(4-Chlorophenyl)piperazinyl piperidyl ketone	IC50	30000.0 [1]
	7-Benzoyl-4,5-dihydro-1,4-benzoxazepin-3(2H)-one	Ki	137000.0 [1]
	3-(2-Carboxyethylamino)naphthalene-2-carboxylic acid	Ki	33000.0 [1]
	[4-(4-Fluoro-phenyl)-piperazin-1-yl]-morpholin-4-yl-methanone	IC50	30000.0 [1]
	5-Chloro-4-Hydroxybiphenyl-3-Carboxylic Acid	Ki	21.0 [1]
	N-(3-Carboxyphenyl)anthranilic acid	IC50	4160.0 [1]
	(E)-3-[3-(3-Methylbut-2-enyl)-4-(3-phenylpropanoyloxy)phenyl]prop-2-enoic acid	IC50	100000.0 [1]
	2-[(4-Methylphenyl)amino]benzoic acid	IC50	1460.0 [1]
	Methyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate	IC50	100000.0 [1]
	1-{4-[(2-Methylpiperidin-1-yl)sulfonyl]phenyl}pyrrolidin-2-one	IC50	30000.0 [1]
	N-(3-Methylphenyl)anthranilic acid	IC50	380.0 [1]
	[4-(4-Chlorophenyl)piperazin-1-yl](morpholin-4-yl)methanone	IC50	30000.0 [1]
	[1-(4-Fluorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid	IC50	60970.0 [1]
	3-(3,4-Dihydroisoquinolin-2(1h)-Ylsulfonyl)-N-Methylbenzamide	IC50	30000.0 [1]
	2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-methylsulfonylacetamide	IC50	65390.0 [1]
	1-(4-Bromophenyl)sulfonylindole-3-carboxylic acid	IC50	30000.0 [1]
	N-(2-Methoxyphenyl)anthranilic acid	IC50	1280.0 [1]
	1-Naphthalen-2-ylsulfonylpyrrolidine-3-carboxylic acid	IC50	30000.0 [1]
	5-Bromo-3-phenylsalicylic acid	Ki	1970.0 [1]
	3-(3,4-Dihydro-2H-quinoline-1-sulfonyl)-benzoic acid	IC50	30000.0 [1]
	2-Methyl-1-{1-[(5-methyl-1H-indol-2-yl)carbonyl]piperidin-4-yl}propan-2-ol	IC50	20000.0 [1]
	3-(Naphthalen-2-ylsulfamoyl)benzoic acid	IC50	30000.0 [1]
	3-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)-N,N-dimethylbenzamide	IC50	30000.0 [1]
	Morpholin-4-yl[4-(4-nitrophenyl)piperazin-1-yl]methanone	IC50	30000.0 [1]
	3-[(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acid	IC50	30000.0 [1]
	3-(2,3-Dihydro-indole-1-sulfonyl)-benzoic acid	IC50	30000.0 [1]
	3-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)benzamide	IC50	30000.0 [1]
	(E)-2-(4-Fluorophenyl)-3-(4-methylsulfonylphenyl)prop-2-enoic acid	IC50	44600.0 [1]
	(E)-3-(4-Methylsulfonylphenyl)-2-phenylprop-2-enoic acid	IC50	34400.0 [1]
	3-[2-(4-Methoxyphenyl)ethylsulfamoyl]benzoic acid	IC50	30000.0 [1]
	3-[2-(4-Chlorophenyl)ethylsulfamoyl]benzoic acid	IC50	30000.0 [1]
	3-[2-(2-Fluorophenyl)ethylsulfamoyl]benzoic acid	IC50	30000.0 [1]
	3-[2-(3-Chlorophenyl)ethylsulfamoyl]benzoic acid	IC50	30000.0 [1]
	2-(4-Chloroanilino)benzoic acid	IC50	410.0 [1]
	5-Fluoro-4-hydroxybiphenyl-3-carboxylic acid	Ki	1.5 [1]
	3-[(4-Nitronaphthalen-1-Yl)amino]benzoic Acid	IC50	8170.0 [1]
	(S)-1-(Naphthalene-2-sulfonyl)-piperidine-3-carboxylic acid	IC50	3000.0 [1]
	(R)-1-(Naphthalene-2-sulfonyl)-piperidine-3-carboxylic acid	IC50	30000.0 [1]
	1-[3-(2-Chlorophenyl)phenyl]sulfonylpiperidine-3-carboxylic acid	IC50	30000.0 [1]
	1-[4-(3-Phenylphenyl)phenyl]sulfonylpiperidine-3-carboxylic acid	IC50	30000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Aldo-keto reductase family 1 member C2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/aldo-keto-reductase-family-1-member-c2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 10). Quest Database™ Aldo-keto reductase family 1 member C2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/aldo-keto-reductase-family-1-member-c2-inhibitors-ic50-ki.
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