Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	N-Tert-butyl-8-[[[(1S,2S)-2-(3-methyl-1,2,4-oxadiazol-5-yl)cyclopropanecarbonyl]amino]methyl]-5-[3-(trifluoromethoxy)phenyl]-3,4-dihydro-1H-isoquinoline-2-carboxamide	IC50	10000.0 [1]
	(3S)-N-(2,4-Difluorophenyl)-3-ethyl-3-methyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepine-7-sulfonamide	IC50	6.31 [1], 12.59 [2]
	N-(4-Methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	55.0 [1], 4264.0 [2]
	5-(2-Ethyltetrazol-5-yl)-4-(4-methylphenyl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one	IC50	121.0 [1], 33330.0 [2]
	6-Methyl-4-(4-methylphenyl)-2-oxo-6-pentyl-1,3-dihydropyridine-3-carbonitrile	IC50	651.0 [1], 2049.0 [2]
	(6R)-N-(4-Methoxyphenyl)-4-(4-methylphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)piperidine-3-carboxamide	IC50	416.0 [1], 8430.0 [2]
	2-(4-Methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	20.0 [1], 401.0 [2]
	4-(4-Methylphenyl)-2-[4-[2-[(2-methylpropan-2-yl)oxy]ethoxy]phenyl]-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	126.0 [1], 656.0 [2]
	4-(4-Methylphenyl)-6-oxo-2-[4-(3-phenylpropoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	13.0 [1], 5199.0 [2]
	2-[4-(2-Cyclopentylethoxy)phenyl]-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	57.0 [1], 396.0 [2]
	2-[4-(3-Methylbutoxy)phenyl]-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	15.0 [1], 263.0 [2]
	2-[4-(4-Methoxyphenyl)phenyl]-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	164.0 [1], 2546.0 [2]
	N-(4-Fluorophenyl)-2-(4-methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	15.0 [1], 170.0 [2]
	4-(4-Methylphenyl)-6-oxo-2-(4-pentylphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	77.0 [1], 403.0 [2]
	4-(4-Methylphenyl)-6-oxo-2-(4-pyridin-2-ylphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	60.0 [1], 5387.0 [2]
	N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-phenoxyphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	8.0 [1], 60.0 [2]
	N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-pyrimidin-4-yloxyphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	64.0 [1], 127.0 [2]
	N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-pyrazin-2-ylphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	95.0 [1], 242.0 [2]
	N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-pentylphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	13.0 [1], 63.0 [2]
	N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-pyrimidin-2-yloxyphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	99.0 [1], 477.0 [2]
	N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-phenylmethoxyphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	20.0 [1], 258.0 [2]
	4-(4-Methylphenyl)-6-oxo-N-pentyl-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	20.0 [1], 846.0 [2]
	4-(4-Methylphenyl)-6-oxo-N-(2-phenylethyl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	16.0 [1], 412.0 [2]
	N-(3-Methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	29.0 [1], 275.0 [2]
	4-(4-Methylphenyl)-6-oxo-N-phenyl-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	4.0 [1], 53.0 [2]
	N-(2-Chlorophenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	12.0 [1], 441.0 [2]
	N-(4-Chlorophenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	24.0 [1], 156.0 [2]
	4-(3-Methoxyphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	280.0 [1], 761.0 [2]
	4-(4-Methoxyphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	27.0 [1], 89.0 [2]
	4-(4-Cyanophenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	414.0 [1], 731.0 [2]
	4-(4-Fluorophenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	697.0 [1], 2476.0 [2]
	4-(3-Chlorophenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	1282.0 [1], 7523.0 [2]
	4-(3-Cyanophenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	983.0 [1], 9230.0 [2]
	6-Oxo-4-phenyl-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	1917.0 [1], 2931.0 [2]
	4-(4-Chlorophenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	214.0 [1], 3519.0 [2]
	4-Naphthalen-2-yl-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	25.0 [1], 397.0 [2]
	6-Oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-dihydropyridine-5-carbonitrile	IC50	209.0 [1], 873.0 [2]
	6-Oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-4-[4-(trifluoromethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	45.0 [1], 1856.0 [2]
	4-(4-Ethoxyphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	25.0 [1], 130.0 [2]
	4-(2-Fluoro-4-methoxyphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	2.0 [1], 916.0 [2]
	N,4-Bis(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	2.0 [1], 133.0 [2]
	N-(3-Fluoro-4-methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	2.0 [1], 115.0 [2]
	N-(3-Fluoro-4-methylphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	7.0 [1], 1465.0 [2]
	N-(4-Methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(2,2,2-trifluoroethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	5.0 [1], 28.0 [2]
	4-(4-Methylphenyl)-6-oxo-2-[4-(2,2,2-trifluoroethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	20.0 [1], 731.0 [2]
	4-(4-Methylphenyl)-5-(2H-tetrazol-5-yl)-2-[4-(2,2,2-trifluoroethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one	IC50	78.0 [1], 815.0 [2]
	4-[4-(Difluoromethoxy)phenyl]-5-(2H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one	IC50	37.0 [1], 46.0 [2]
	4-(4-Methylphenyl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-5-[4-(trifluoromethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one	IC50	4.0 [1], 32.0 [2]
	4-(2-Fluoro-4-methoxyphenyl)-5-(2H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one	IC50	43.0 [1], 95.0 [2]
	5-(2H-Tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-dihydropyridin-6-one	IC50	69.0 [1], 154.0 [2]
	4-(4-Chlorophenyl)-5-(2H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one	IC50	108.0 [1], 379.0 [2]
	4-(4-Methylphenyl)-6-oxo-N-[6-(2H-tetrazol-5-yl)pyridin-3-yl]-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	7.0 [1], 9.0 [2]
	2-(4-Bromophenyl)-4-(4-methylphenyl)-5-(2H-tetrazol-5-yl)-2-(trifluoromethyl)-1,3-dihydropyridin-6-one	IC50	639.0 [1], 1297.0 [2]
	4-(4-Methylphenyl)-5-(5H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one	IC50	8.0 [1], 158.0 [2]
	4-(4-Methylphenyl)-2-[4-(4,4,5,5,5-pentafluoropentoxy)phenyl]-5-(2H-tetrazol-5-yl)-2-(trifluoromethyl)-1,3-dihydropyridin-6-one	IC50	4.0 [1], 32.0 [2]
	N-Cyclobutyl-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	6.0 [1], 58.0 [2]
	N-Cyclohexyl-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	20.0 [1], 231.0 [2]
	N-Methyl-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	5.0 [1], 743.0 [2]
	2-[4-(Cyclopenten-1-yl)phenyl]-4-(4-methylphenyl)-6-oxo-N-(2H-tetrazol-5-yl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	33.0 [1], 1874.0 [2]
	2-[3-(Cyclohexen-1-yl)phenyl]-4-(4-methylphenyl)-6-oxo-N-(2H-tetrazol-5-yl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	10.0 [1], 655.0 [2]
	4-(4-Methylphenyl)-N-(1,2-oxazol-5-yl)-6-oxo-2-(trifluoromethyl)-2-[4-(3,3,3-trifluoropropoxy)phenyl]-1,3-dihydropyridine-5-carboxamide	IC50	1.0 [1], 20.0 [2]
	5,5-Difluoro-N-(4-methoxyphenyl)-4-(4-methylphenyl)-2-oxo-6-(trifluoromethyl)-6-[4-(3,3,3-trifluoropropoxy)phenyl]-1H-pyridine-3-carboxamide	IC50	127.0 [1], 1518.0 [2]
	4-(2-Fluoro-4-methoxyphenyl)-5-(tetrazol-1-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one	IC50	10.0 [1], 93.0 [2]
	4-(4-Methoxyphenyl)-5-(tetrazol-1-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one	IC50	4.0 [1], 156.0 [2]
	4-(2,4-Dimethylphenyl)-N-(4-methoxyphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	9.0 [1], 102.0 [2]
	N-[5,5-Difluoro-4-(4-methylphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)-1H-pyridin-3-yl]-3-methyl-1,2-oxazole-5-carboxamide	IC50	3.0 [1], 11.0 [2]
	4-Methyl-N-[4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-1,2-oxazole-5-carboxamide	IC50	84.0 [1], 168.0 [2]
	6-Chloro-N-[4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]pyridazine-3-carboxamide	IC50	75.0 [1], 302.0 [2]
	N-[5,5-Difluoro-4-(4-methylphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)-1H-pyridin-3-yl]-4-methoxybenzamide	IC50	47.0 [1], 1176.0 [2]
	N-[4-[4-(Difluoromethoxy)phenyl]-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-1,2-oxazole-5-carboxamide	IC50	2.0 [1], 8.0 [2]
	2-Chloro-5-fluoro-N-[4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]benzamide	IC50	57.0 [1], 724.0 [2]
	N-[2-(4-Butoxyphenyl)-4-(4-methoxyphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-1,2-oxazole-5-carboxamide	IC50	3.0 [1], 16.0 [2]
	2-N-Hexadecyl-5-N-(4-methoxyphenyl)-2-methyl-4-(4-methylphenyl)-6-oxo-1,3-dihydropyridine-2,5-dicarboxamide	IC50	43.0 [1], 63.0 [2]
	5-N-(4-Methoxyphenyl)-2-methyl-4-(4-methylphenyl)-2-N-octyl-6-oxo-1,3-dihydropyridine-2,5-dicarboxamide	IC50	60.0 [1], 237.0 [2]
	5-N-(4-Methoxyphenyl)-2-methyl-4-(4-methylphenyl)-6-oxo-2-N-(4-phenylbutyl)-1,3-dihydropyridine-2,5-dicarboxamide	IC50	47.0 [1], 78.0 [2]
	3-Bromo-N-[4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-1,2-oxazole-5-carboxamide	IC50	2.0 [1], 24.0 [2]
	N-[4-(4-Methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-3-phenylmethoxy-1,2-oxazole-5-carboxamide	IC50	30.0 [1], 36.0 [2]
	N-(5-Methoxypyrazin-2-yl)-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-2-[4-(5,5,5-trifluoropentoxy)phenyl]-1,3-dihydropyridine-5-carboxamide	IC50	10.0 [1], 21.0 [2]
	(2S)-N-(4-Methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	2.0 [1], 14.0 [2]
	2-N-Heptyl-5-N-(4-methoxyphenyl)-2-methyl-4-(4-methylphenyl)-6-oxo-1,3-dihydropyridine-2,5-dicarboxamide	IC50	102.0 [1], 237.0 [2]
	N-(6-Methoxypyridin-3-yl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	5.0 [1], 11.0 [2]
	N-Cyclopropyl-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	21.0 [1], 94.0 [2]
	4-(4-Methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-N-[4-(trifluoromethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	1.0 [1], 89.0 [2]
	N-(4-Hydroxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide	IC50	1.0 [1], 14.0 [2]
	4-[4-(Difluoromethoxy)phenyl]-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	16.0 [1], 175.0 [2]
	4-(4-Methylphenyl)-5-(2H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one	IC50	8.0 [1], 35.0 [2]
	4-(4-Methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	171.0 [1], 5073.0 [2]
	4-(4-Methylphenyl)-6-oxo-2-(trifluoromethyl)-2-[4-(3,3,3-trifluoropropoxy)phenyl]-1,3-dihydropyridine-5-carbonitrile	IC50	14.0 [1], 91.0 [2]
	4-[4-(Difluoromethoxy)phenyl]-5-(tetrazol-1-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one	IC50	6.0 [1], 53.0 [2]
	5-Methyl-N-[4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-1,3,4-oxadiazole-2-carboxamide	IC50	8.0 [1], 34.0 [2]
	2-Methyl-N-[(2S)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]benzamide	IC50	24.0 [1], 672.0 [2]
	(2R)-4-(4-Methylphenyl)-5-(2H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one	IC50	261.0 [1], 1400.0 [2]
	2-(4-Butoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile	IC50	21.0 [1], 309.0 [2]
	4-(4-Methylphenyl)-5-nitro-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one	IC50	35.0 [1], 3333.0 [2]
	4-(4-Methylphenyl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-5-[5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl]-1,3-dihydropyridin-6-one	IC50	138.0 [1], 2716.0 [2]
	4-(4-Methylphenyl)-5-(2H-tetrazol-5-yl)-2-[4-(6,6,6-trifluorohexoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one	IC50	48.0 [1], 407.0 [2]
	2-Methyl-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-N-[4-(trifluoromethoxy)phenyl]-1,3-dihydropyridine-5-carboxamide	IC50	13.0 [1], 48.0 [2]
	(6S)-N-(4-Methoxyphenyl)-4-(4-methylphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)piperidine-3-carboxamide	IC50	25.0 [1], 416.0 [2]
	(6S)-3-Fluoro-4-(4-methoxyphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)-1H-pyridine-3-carbonitrile	IC50	2049.0 [1], 33330.0 [2]
	(6R)-3-Fluoro-4-(4-methoxyphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)-1H-pyridine-3-carbonitrile	IC50	2049.0 [1], 33330.0 [2]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/alpha-1-6-mannosyl-glycoprotein-2-beta-n-acetylglucosaminyltransferase-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/alpha-1-6-mannosyl-glycoprotein-2-beta-n-acetylglucosaminyltransferase-inhibitors-ic50-ki.
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