 | Tamsulosin | IC50 | 4.8 [1] |
 | Methyl 5-[3-(4,4-diphenylpiperidin-1-yl)propylcarbamoyl]-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3-carboxylate | Ki | 269.0 [1] |
 | Doxazosin | Ki | 0.63 [1], 0.74 [2], 0.81 [3], 1.0 [4] |
 | 3-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-1,5-dihydropyrimido[5,4-b]indole-2,4-dione | Ki | 1.82 [1] |
 | N-((1r,4r)-4-(4-(2-Cyclopropoxyphenyl)piperidin-1-yl)cyclohexyl)-3,4-dimethoxybenzenesulfonamide | Ki | 133.0 [1], 141.0 [2] |
 | N-((1r,4r)-4-(4-(2-Isopropoxyphenyl)piperidin-1-yl)cyclohexyl)-3,4-dimethoxybenzenesulfonamide | Ki | 144.0 [1], 148.0 [2], 151.0 [3] |
 | 3,4-Dimethoxy-N-[4-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperidin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 123.0 [1], 368.0 [2] |
 | N-((1r,4r)-4-(4-(2-(2-Fluoroethoxy)phenyl)piperidin-1-yl)cyclohexyl)-3,4-dimethoxybenzenesulfonamide | Ki | 354.0 [1], 401.0 [2], 4403.0 [3] |
 | N-[4-[4-[2-(2,2-Difluoroethoxy)phenyl]piperidin-1-yl]cyclohexyl]-3,4-dimethoxybenzenesulfonamide | Ki | 278.0 [1], 300.0 [2], 681.0 [3] |
 | 3,4-Dimethoxy-N-[4-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 106.0 [1], 109.0 [2], 126.0 [3] |
 | Yohimbine | Ki | 1.1 [1], 7.2 [2], 966.0 [3] |
 | Rauwolscine | Ki | 0.6 [1], 4.6 [2], 2270.0 [3] |
 | Alfuzosin | Ki | 2.8 [1], 10.0 [2], 12.0 [3] |
 | Azelastine | Ki | 50.12 [1] |
 | Silodosin | IC50 | 116.0 [1], 541.4 [2] |
| Silodosin | Ki | 19.95 [1] |
 | Naftopidil | IC50 | 634.0 [1] |
| Naftopidil | Ki | 19.95 [1] |
 | Indoramin | Ki | 25.0 [1], 29.0 [2], 39.81 [3] |
 | 8-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione dihydrochloride | Ki | 50.12 [1], 630.96 [2], 707.95 [3] |
 | 5-Methylurapidil | Ki | 39.81 [1], 92.0 [2], 535.0 [3] |
 | Niguldipine | Ki | 25.01 [1], 55.0 [2], 85.0 [3] |
 | 7-Chloro-2-ethenyl-3,4,5,6-tetrahydro-4-methylthieno(4,3,2-ef)(3)benzazepine | Ki | 19.95 [1], 23.0 [2] |
 | Benzyl (2S)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2-(tert-butylcarbamoyl)piperazine-1-carboxylate | IC50 | 8.8 [1], 5800.0 [2] |
| Benzyl (2S)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2-(tert-butylcarbamoyl)piperazine-1-carboxylate | Ki | 2.0 [1] |
 | 2-[[(2R)-1-[4-[4-[3-(Azepan-1-yl)propoxy]phenyl]butyl]pyrrolidin-2-yl]methyl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one | Ki | 31.62 [1] |
 | Methyl 1-[3-[[5-carbamoyl-4-(3,4-difluorophenyl)-6-ethyl-2-oxo-1,4-dihydropyrimidine-3-carbonyl]amino]propyl]-4-phenylpiperidine-4-carboxylate | Ki | 250.0 [1], 260.0 [2] |
 | (4S,5S)-4-(3,4-Difluorophenyl)-N-[3-[4-(4-fluorophenyl)piperidin-1-yl]propyl]-5-methyl-2-oxo-1,3-oxazolidine-3-carboxamide | Ki | 119.0 [1], 121.0 [2] |
 | 8-[(2R)-1-[4-(2,4,5-Trifluorophenyl)piperazin-1-yl]propan-2-yl]-8-azaspiro[4.5]decane-7,9-dione | Ki | 165.0 [1], 191.0 [2] |
 | N-[[(3S)-2,3-Dihydro-1,4-benzodioxin-3-yl]methyl]-2-(2,6-dimethoxyphenoxy)ethanamine;hydrochloride | Ki | 5.75 [1] |
 | 5-N-[3-(4,4-Diphenylpiperidin-1-yl)propyl]-3-N,2,6-trimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxamide | Ki | 416.0 [1], 416.87 [2], 489.78 [3] |
 | 5-N-[3-(4,4-Diphenylpiperidin-1-yl)propyl]-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxamide | Ki | 330.0 [1], 331.13 [2], 407.0 [3] |
 | N-[(2,2-Diphenyl-1,3-dioxolan-4-yl)methyl]-2-phenoxyethanamine;oxalic acid | Ki | 63.1 [1] |
 | [(4As,8aR)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(furan-2-yl)methanone | Ki | 0.07 [1], 0.13 [2], 0.69 [3] |
 | Phentolamine | Ki | 4.8 [1], 47.4 [2] |
 | Cyclohexanecarboxamide, n-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-n-2-pyridinyl- | Ki | 66.07 [1], 322.0 [2] |
 | Dexniguldipine | Ki | 54.95 [1], 56.0 [2] |
 | Abanoquil | Ki | 0.08 [1], 0.11 [2] |
 | Upidosin | Ki | 3.9 [1], 31.62 [2] |
 | N,N-Diallyl-5-methoxytryptamine | Ki | 10000.0 [1] |
 | CID 9872515 | Ki | 79.43 [1] |
 | CID 9891980 | IC50 | 1.2 [1] |
| CID 9891980 | Ki | 0.45 [1] |
 | 2-(2-Biphenylyloxymethyl)-2-imidazoline | IC50 | 741.31 [1], 2398.83 [2] |
 | N-[2-(2,6-Dimethoxyphenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine | Ki | 0.54 [1] |
 | 5-Chloro-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-3-methyl-1-benzothiophene-2-sulfonamide | Ki | 1995.26 [1] |
 | Methyl 4-(3,4-difluorophenyl)-3-[3-(4-methoxycarbonyl-4-phenylpiperidin-1-yl)propylcarbamoyl]-6-methyl-2-oxo-1,4-dihydropyrimidine-5-carboxylate | Ki | 45.0 [1] |
 | 2-(2,6-Dimethoxyphenoxy)-N-[[(2R)-6,6-diphenyl-1,4-dioxan-2-yl]methyl]ethanamine | Ki | 194.98 [1], 323.59 [2] |
 | N-[[(2R)-6,6-Diphenyl-1,4-dioxan-2-yl]methyl]-2-(2-methoxyphenoxy)ethanamine | Ki | 21.88 [1], 56.23 [2] |
 | N-[[(2R)-6,6-Diphenyl-1,4-dioxan-2-yl]methyl]-2-phenoxyethanamine | Ki | 52.48 [1], 120.23 [2] |
 | 5-N-[4-(4,4-Diphenylpiperidin-1-yl)butyl]-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxamide | Ki | 331.13 [1], 367.0 [2] |
 | N-[[(3R)-2,3-Dihydro-1,4-benzodioxin-3-yl]methyl]-2-(2,6-dimethoxyphenoxy)ethanamine;hydrochloride | Ki | 72.44 [1] |
 | 3-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl]-1H-[1]benzothiolo[3,2-d]pyrimidine-2,4-dione | Ki | 8.91 [1] |
 | Methyl 1-[3-[[5-carbamoyl-4-(2,4-difluorophenyl)-6-ethyl-2-oxo-1,4-dihydropyrimidine-3-carbonyl]amino]propyl]-4-phenylpiperidine-4-carboxylate | Ki | 220.0 [1], 340.0 [2] |
 | Methyl 4-(3,4-difluorophenyl)-3-[5-(4-methoxycarbonyl-4-phenylpiperidin-1-yl)pentyl]-6-methyl-2-oxo-1,4-dihydropyrimidine-5-carboxylate | Ki | 140.0 [1] |
 | Methyl 1-[3-[[5-carbamoyl-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3-carbonyl]amino]propyl]-4-phenylpiperidine-4-carboxylate | Ki | 2740.0 [1], 3700.0 [2] |
 | Methyl 5-[4-(4,4-diphenylpiperidin-1-yl)butylcarbamoyl]-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3-carboxylate | Ki | 64.57 [1], 134.9 [2] |
 | 3-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl]-2-methyl-5H-pyrimido[5,4-b]indol-4-one | Ki | 20.89 [1] |
 | Methyl 5-[3-(4-methoxycarbonyl-4-phenylpiperidin-1-yl)propylcarbamoyl]-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3-carboxylate | Ki | 700.0 [1] |
 | 4-[(4-Chlorophenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one | Ki | 10.0 [1], 12.59 [2] |
 | 5-Chloro-2-methoxy-N-[4-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 78.0 [1], 250.0 [2] |
 | 1-[3-(Di-p-tolylacetylamino)propyl]-4-phenylpiperidine-4-carbonitrile | Ki | 2000.0 [1] |
 | N-[(6,6-Diphenyl-1,4-dioxan-2-yl)methyl]-2-(2-methoxyphenoxy)ethanamine | Ki | 56.23 [1] |
 | 1-(1,4-Dioxaspiro[4.5]decan-3-ylmethyl)-4-(2-methoxyphenyl)piperazine | Ki | 125.89 [1] |
 | 1-[3-(Di-p-tolylacetylamino)propyl]-4-phenylpiperidine-4-carboxylic acid methyl ester | Ki | 170.0 [1], 450.0 [2] |
 | 1-[3-(4-Methylphenylacetylamino)propyl]-4-phenyl-4-piperidinecarboxylic acid methyl ester | Ki | 3000.0 [1] |
 | 3-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl]-2-methyl-[1]benzothiolo[3,2-d]pyrimidin-4-one | Ki | 17.38 [1] |
 | N-((1r,4r)-4-(4-(2-Isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-4-(methylsulfonyl)benzenesulfonamide | Ki | 195.0 [1], 392.0 [2] |
 | 2-Methoxy-5-methyl-N-[4-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 162.0 [1], 218.0 [2] |
 | 5-Fluoro-2-methoxy-N-[4-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 162.0 [1], 714.0 [2] |
 | 2,4-Dichloro-N-[4-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 177.0 [1], 596.0 [2] |
 | [(4Ar,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone | Ki | 0.42 [1], 1.41 [2] |
 | N-[(2,2-Diphenyl-1,3-dioxolan-4-yl)methyl]-2-(2-methoxyphenoxy)ethanamine;oxalic acid | Ki | 45.71 [1], 46.77 [2] |
 | N-[[(3S)-2,3-Dihydro-1,4-benzodioxin-3-yl]methyl]-2-(2-methoxynaphthalen-1-yl)oxyethanamine;hydrochloride | Ki | 15.85 [1] |
 | 1-[4-[4-(2-Methoxyphenyl)piperazin-1-yl]butyl]-4-phenylpiperidine-2,6-dione | Ki | 3.98 [1], 23.99 [2] |
 | 5-[(3,4-Dimethoxyphenyl)methyl]-5-azahexacyclo[5.4.1.02,6.03,10.04,8.09,12]dodecan-4-ol | Ki | 2766.0 [1] |
 | 8-{2-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione | Ki | 62.62 [1], 67.0 [2] |
 | 8-{2-[4-(2,5-Difluorophenyl)piperazin-1-yl]ethyl)-8-azaspiro[4.5]decane-7,9-dione | Ki | 5.88 [1], 54.0 [2] |
 | 5-O-[3-(4,4-Diphenylpiperidin-1-yl)propyl] 3-O-methyl 2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate | Ki | 50.0 [1], 85.0 [2] |
 | N,N'-Bis(8-methylquinolin-4-yl)ethane-1,2-diamine | Ki | 39.81 [1], 40.0 [2] |
 | 4-Amino-6,7-dimethoxy-2-[(3S)-3-(t-butylcarbamoyl)-1-piperazinyl]quinazoline | IC50 | 31.0 [1] |
| 4-Amino-6,7-dimethoxy-2-[(3S)-3-(t-butylcarbamoyl)-1-piperazinyl]quinazoline | Ki | 25.0 [1] |
 | 3,4-Dimethoxy-N-[4-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 39.0 [1], 86.0 [2] |
 | 3,4-Difluoro-N-((1r,4r)-4-(4-(2-isopropoxyphenyl)piperidin-1-yl)cyclohexyl)benzenesulfonamide | Ki | 470.0 [1], 1385.0 [2] |
 | 5-Chloro-N-[4-[4-(2-cyclopropyloxyphenyl)piperidin-1-yl]cyclohexyl]-2-methoxybenzenesulfonamide | Ki | 82.0 [1], 305.0 [2] |
 | 5-Chloro-N-((1r,4r)-4-(4-(2-cyclopropoxyphenyl)piperidin-1-yl)cyclohexyl)-2-fluorobenzenesulfonamide | Ki | 107.0 [1], 337.0 [2] |
 | N-[4-[4-[2-(2,2,2-Trifluoroethoxy)phenyl]piperidin-1-yl]cyclohexyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide | Ki | 91.0 [1], 92.0 [2] |
 | 5-Chloro-2-methoxy-N-[4-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperidin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 216.0 [1], 703.0 [2] |
 | 5-Chloro-2-fluoro-N-[4-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperidin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 181.0 [1], 787.0 [2] |
 | 3-(Difluoromethoxy)-N-[4-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperidin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 261.0 [1], 355.0 [2] |
 | N-[4-[4-(4-Fluoro-2-propan-2-yloxyphenyl)piperidin-1-yl]cyclohexyl]-3,4-dimethoxybenzenesulfonamide | Ki | 639.0 [1], 690.0 [2] |
 | N-[4-[4-(5-Fluoro-2-propan-2-yloxyphenyl)piperidin-1-yl]cyclohexyl]-3,4-dimethoxybenzenesulfonamide | Ki | 299.0 [1], 1487.0 [2] |
 | N,N'-Bis(6-methylquinolin-4-yl)ethane-1,2-diamine | Ki | 19.0 [1], 19.05 [2] |
 | N,N'-Bis(7-methylquinolin-4-yl)ethane-1,2-diamine | Ki | 47.86 [1], 48.0 [2] |
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