 | Prazosin | IC50 | 0.88 [1] |
 | Tamsulosin | IC50 | 1.4 [1] |
 | Methyl 5-[3-(4,4-diphenylpiperidin-1-yl)propylcarbamoyl]-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3-carboxylate | Ki | 1047.0 [1] |
 | Cyclazosin | Ki | 0.17 [1], 3.24 [2], 31.62 [3] |
 | 3-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-1,5-dihydropyrimido[5,4-b]indole-2,4-dione | Ki | 0.36 [1], 2.75e+18 [2] |
 | N-((1r,4r)-4-(4-(2-Cyclopropoxyphenyl)piperidin-1-yl)cyclohexyl)-3,4-dimethoxybenzenesulfonamide | Ki | 2.0 [1], 34.0 [2] |
 | N-((1r,4r)-4-(4-(2-Isopropoxyphenyl)piperidin-1-yl)cyclohexyl)-3,4-dimethoxybenzenesulfonamide | Ki | 0.77 [1], 1.7 [2], 40.0 [3] |
 | 3,4-Dimethoxy-N-[4-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperidin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 2.2 [1], 23.0 [2] |
 | N-((1r,4r)-4-(4-(2-(2-Fluoroethoxy)phenyl)piperidin-1-yl)cyclohexyl)-3,4-dimethoxybenzenesulfonamide | Ki | 5.5 [1], 8.8 [2], 49.0 [3] |
 | N-[4-[4-[2-(2,2-Difluoroethoxy)phenyl]piperidin-1-yl]cyclohexyl]-3,4-dimethoxybenzenesulfonamide | Ki | 4.1 [1], 8.6 [2], 86.0 [3] |
 | 3,4-Dimethoxy-N-[4-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 0.68 [1], 1.0 [2], 24.0 [3] |
 | Phentolamine | Ki | 7.6 [1], 11.0 [2], 19.4 [3] |
 | Yohimbine | Ki | 1.6 [1], 289.0 [2], 498.0 [3] |
 | Silodosin | IC50 | 6.3 [1], 27.3 [2] |
| Silodosin | Ki | 2.0 [1] |
 | Naftopidil | IC50 | 55.2 [1] |
| Naftopidil | Ki | 1.2 [1] |
 | 8-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione dihydrochloride | Ki | 1.05 [1], 1.29 [2], 6.31 [3] |
 | 7-Chloro-2-ethenyl-3,4,5,6-tetrahydro-4-methylthieno(4,3,2-ef)(3)benzazepine | Ki | 1.6 [1], 3.16 [2] |
 | Methyl 1-[3-[[5-carbamoyl-4-(3,4-difluorophenyl)-6-ethyl-2-oxo-1,4-dihydropyrimidine-3-carbonyl]amino]propyl]-4-phenylpiperidine-4-carboxylate | Ki | 340.0 [1], 350.0 [2] |
 | (4S,5S)-4-(3,4-Difluorophenyl)-N-[3-[4-(4-fluorophenyl)piperidin-1-yl]propyl]-5-methyl-2-oxo-1,3-oxazolidine-3-carboxamide | Ki | 122.0 [1], 133.0 [2] |
 | 8-[(2R)-1-[4-(2,4,5-Trifluorophenyl)piperazin-1-yl]propan-2-yl]-8-azaspiro[4.5]decane-7,9-dione | Ki | 1.3 [1], 1.6 [2] |
 | N-[[(3S)-2,3-Dihydro-1,4-benzodioxin-3-yl]methyl]-2-(2,6-dimethoxyphenoxy)ethanamine;hydrochloride | Ki | 0.51 [1] |
 | 5-N-[3-(4,4-Diphenylpiperidin-1-yl)propyl]-3-N,2,6-trimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxamide | Ki | 616.0 [1], 616.6 [2], 758.58 [3] |
 | N-[(2,2-Diphenyl-1,3-dioxolan-4-yl)methyl]-2-phenoxyethanamine;oxalic acid | Ki | 11.48 [1], 11.75 [2] |
 | Rauwolscine | Ki | 3.5 [1], 1320.0 [2] |
 | Brimonidine | Ki | 846.0 [1], 933.25 [2] |
 | Oxymetazoline | Ki | 1348.96 [1], 1398.0 [2] |
 | Alfuzosin | Ki | 3.16 [1], 3.6 [2] |
 | Indoramin | Ki | 110.0 [1], 158.49 [2] |
 | 5-Methylurapidil | Ki | 10.0 [1], 21.0 [2] |
 | Niguldipine | Ki | 100.0 [1], 191.0 [2] |
 | Dexniguldipine | Ki | 100.0 [1], 170.0 [2] |
 | Upidosin | Ki | 1.5 [1], 2.51 [2] |
 | N,N-Diallyl-5-methoxytryptamine | Ki | 10000.0 [1] |
 | CID 9872515 | Ki | 63.1 [1], 100.0 [2] |
 | 2-(2-Biphenylyloxymethyl)-2-imidazoline | IC50 | 323.59 [1], 549.54 [2] |
 | N-[2-(2,6-Dimethoxyphenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine | Ki | 0.07 [1] |
 | Methyl 4-(3,4-difluorophenyl)-3-[3-(4-methoxycarbonyl-4-phenylpiperidin-1-yl)propylcarbamoyl]-6-methyl-2-oxo-1,4-dihydropyrimidine-5-carboxylate | Ki | 140.0 [1] |
 | 2-(2,6-Dimethoxyphenoxy)-N-[[(2R)-6,6-diphenyl-1,4-dioxan-2-yl]methyl]ethanamine | Ki | 56.23 [1], 66.07 [2] |
 | N-[[(2R)-6,6-Diphenyl-1,4-dioxan-2-yl]methyl]-2-(2-methoxyphenoxy)ethanamine | Ki | 1.15 [1], 1.38 [2] |
 | N-[[(2R)-6,6-Diphenyl-1,4-dioxan-2-yl]methyl]-2-phenoxyethanamine | Ki | 3.24 [1], 3.63 [2] |
 | 5-N-[4-(4,4-Diphenylpiperidin-1-yl)butyl]-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxamide | Ki | 398.0 [1], 398.11 [2] |
 | N-[[(3R)-2,3-Dihydro-1,4-benzodioxin-3-yl]methyl]-2-(2,6-dimethoxyphenoxy)ethanamine;hydrochloride | Ki | 10.47 [1] |
 | 5-N-[3-(4,4-Diphenylpiperidin-1-yl)propyl]-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxamide | Ki | 346.0 [1], 602.56 [2] |
 | 3-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl]-1H-[1]benzothiolo[3,2-d]pyrimidine-2,4-dione | Ki | 1.26 [1] |
 | Methyl 1-[3-[[5-carbamoyl-4-(2,4-difluorophenyl)-6-ethyl-2-oxo-1,4-dihydropyrimidine-3-carbonyl]amino]propyl]-4-phenylpiperidine-4-carboxylate | Ki | 340.0 [1], 440.0 [2] |
 | Methyl 4-(3,4-difluorophenyl)-3-[5-(4-methoxycarbonyl-4-phenylpiperidin-1-yl)pentyl]-6-methyl-2-oxo-1,4-dihydropyrimidine-5-carboxylate | Ki | 150.0 [1] |
 | Methyl 5-[4-(4,4-diphenylpiperidin-1-yl)butylcarbamoyl]-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3-carboxylate | Ki | 144.54 [1], 331.13 [2] |
 | 3-[2-[4-(4-Propan-2-ylphenyl)piperazin-1-yl]ethyl]-1,5-dihydropyrimido[5,4-b]indole-2,4-dione | Ki | 35.48 [1], 2.82e+16 [2] |
 | 3-[2-[4-(4-Butan-2-ylphenyl)piperazin-1-yl]ethyl]-1,5-dihydropyrimido[5,4-b]indole-2,4-dione | Ki | 60.26 [1], 1.66e+16 [2] |
 | 3-[2-[4-(4-Butylphenyl)piperazin-1-yl]ethyl]-1,5-dihydropyrimido[5,4-b]indole-2,4-dione | Ki | 245.47 [1], 4073800000000000.0 [2] |
 | 3-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl]-2-methyl-5H-pyrimido[5,4-b]indol-4-one | Ki | 0.41 [1], 2.45e+18 [2] |
 | 3-[2-[4-(4-Tert-butylphenyl)piperazin-1-yl]ethyl]-1,5-dihydropyrimido[5,4-b]indole-2,4-dione | Ki | 19.95 [1], 5.01e+16 [2] |
 | 5-Chloro-2-methoxy-N-[4-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 0.75 [1], 11.0 [2] |
 | 1-[3-(Di-p-tolylacetylamino)propyl]-4-phenylpiperidine-4-carbonitrile | Ki | 1400.0 [1] |
 | N-[(6,6-Diphenyl-1,4-dioxan-2-yl)methyl]-2-(2-methoxyphenoxy)ethanamine | Ki | 1.15 [1] |
 | 1-(1,4-Dioxaspiro[4.5]decan-3-ylmethyl)-4-(2-methoxyphenyl)piperazine | Ki | 1000.0 [1] |
 | 1-[3-(Di-p-tolylacetylamino)propyl]-4-phenylpiperidine-4-carboxylic acid methyl ester | Ki | 960.0 [1], 975.0 [2] |
 | 1-[3-(4-Methylphenylacetylamino)propyl]-4-phenyl-4-piperidinecarboxylic acid methyl ester | Ki | 3400.0 [1] |
 | 3-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl]-2-methyl-[1]benzothiolo[3,2-d]pyrimidin-4-one | Ki | 0.4 [1] |
 | N-((1r,4r)-4-(4-(2-Isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-4-(methylsulfonyl)benzenesulfonamide | Ki | 3.4 [1], 22.0 [2] |
 | 2-Methoxy-5-methyl-N-[4-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 7.0 [1], 31.0 [2] |
 | 5-Fluoro-2-methoxy-N-[4-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 5.0 [1], 66.0 [2] |
 | 2,4-Dichloro-N-[4-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 0.64 [1], 8.6 [2] |
 | [(4Ar,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone | Ki | 0.17 [1], 3.89 [2] |
 | N-[(2,2-Diphenyl-1,3-dioxolan-4-yl)methyl]-2-(2-methoxyphenoxy)ethanamine;oxalic acid | Ki | 9.33 [1] |
 | N-[[(3S)-2,3-Dihydro-1,4-benzodioxin-3-yl]methyl]-2-(2-methoxynaphthalen-1-yl)oxyethanamine;hydrochloride | Ki | 6.61 [1] |
 | 1-[4-[4-(2-Methoxyphenyl)piperazin-1-yl]butyl]-4-phenylpiperidine-2,6-dione | Ki | 2.0 [1], 15.85 [2] |
 | 5-Methyl-1,5-diazapentacyclo[10.8.1.02,7.08,21.013,18]henicosa-2(7),8(21),9,11,13,15,17-heptaene | Ki | 293.0 [1], 295.12 [2] |
 | [(4As,8aR)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(furan-2-yl)methanone | Ki | 0.06 [1], 3.24 [2] |
 | 5-O-[3-(4,4-Diphenylpiperidin-1-yl)propyl] 3-O-methyl 2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate | Ki | 210.0 [1], 302.0 [2] |
 | N,N'-Bis(8-methylquinolin-4-yl)ethane-1,2-diamine | Ki | 478.63 [1], 479.0 [2] |
 | Methyl 4-(3,4-difluorophenyl)-3-[5-(4,4-diphenylpiperidin-1-yl)pentyl]-2,6-dimethyl-4H-pyrimidine-5-carboxylate | Ki | 110.0 [1], 180.0 [2] |
 | 3,4-Dimethoxy-N-[4-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 0.35 [1], 8.3 [2] |
 | 3,4-Difluoro-N-((1r,4r)-4-(4-(2-isopropoxyphenyl)piperidin-1-yl)cyclohexyl)benzenesulfonamide | Ki | 7.3 [1], 87.0 [2] |
 | 5-Chloro-N-[4-[4-(2-cyclopropyloxyphenyl)piperidin-1-yl]cyclohexyl]-2-methoxybenzenesulfonamide | Ki | 2.6 [1], 47.0 [2] |
 | 5-Chloro-N-((1r,4r)-4-(4-(2-cyclopropoxyphenyl)piperidin-1-yl)cyclohexyl)-2-fluorobenzenesulfonamide | Ki | 2.1 [1], 32.0 [2] |
 | N-[4-[4-[2-(2,2,2-Trifluoroethoxy)phenyl]piperidin-1-yl]cyclohexyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide | Ki | 3.0 [1], 26.0 [2] |
 | 5-Chloro-2-methoxy-N-[4-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperidin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 1.6 [1], 36.0 [2] |
 | 5-Chloro-2-fluoro-N-[4-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperidin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 0.98 [1], 44.0 [2] |
 | 3-(Difluoromethoxy)-N-[4-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperidin-1-yl]cyclohexyl]benzenesulfonamide | Ki | 5.9 [1], 70.0 [2] |
 | N-[4-[4-(4-Fluoro-2-propan-2-yloxyphenyl)piperidin-1-yl]cyclohexyl]-3,4-dimethoxybenzenesulfonamide | Ki | 12.0 [1], 60.0 [2] |
 | N-[4-[4-(5-Fluoro-2-propan-2-yloxyphenyl)piperidin-1-yl]cyclohexyl]-3,4-dimethoxybenzenesulfonamide | Ki | 1.6 [1], 53.0 [2] |
 | N,N'-Bis(6-methylquinolin-4-yl)ethane-1,2-diamine | Ki | 489.78 [1], 490.0 [2] |
 | N,N'-Bis(7-methylquinolin-4-yl)ethane-1,2-diamine | Ki | 204.0 [1], 204.17 [2] |
 | N,N'-Bis(7-methoxyquinolin-4-yl)ethane-1,2-diamine | Ki | 213.8 [1], 214.0 [2] |
 | N,N'-Bis(6-methylquinolin-4-yl)heptane-1,7-diamine | Ki | 478.63 [1], 479.0 [2] |
 | N,N'-Bis(6-methoxyquinolin-4-yl)heptane-1,7-diamine | Ki | 371.54 [1], 372.0 [2] |
 | N,N'-Bis(7-methylquinolin-4-yl)heptane-1,7-diamine | Ki | 489.78 [1], 490.0 [2] |
 | N,N'-Bis(7-methoxyquinolin-4-yl)heptane-1,7-diamine | Ki | 229.0 [1], 229.09 [2] |
 | N,N'-Bis(8-methoxyquinolin-4-yl)heptane-1,7-diamine | Ki | 758.58 [1], 759.0 [2] |
 | 1,7-Heptanediamine, N,N'-di-4-quinolinyl- | Ki | 309.0 [1], 309.03 [2] |
 | 1,2-Ethanediamine, N,N-di-4-quinolinyl- | Ki | 331.0 [1], 331.13 [2] |
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