 | Yohimbine | IC50 | 3.67 [1], 8.4 [2] |
| Yohimbine | Ki | 3.1 [1], 7.5 [2] |
 | Terazosin | Ki | 549.54 [1], 550.0 [2], 1500.0 [3], 3702.0 [4], 5187.0 [5] |
 | Clozapine | Ki | 24.0 [1], 34.0 [2], 185.0 [3], 1000.0 [4] |
 | Phentolamine | Ki | 1.7 [1], 2.25 [2], 2.6 [3], 55.9 [4] |
 | Idazoxan | IC50 | 8.32 [1] |
| Idazoxan | Ki | 7.08 [1], 8.0 [2] |
 | 2-[1-(2-Prop-2-enylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 57.54 [1] |
 | Methyl 5-[3-(4,4-diphenylpiperidin-1-yl)propylcarbamoyl]-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3-carboxylate | Ki | 1200.0 [1], 1202.26 [2], 2417.0 [3], 3300.0 [4] |
 | 2-[1-(2-Biphenylyloxy)ethyl]-2-imidazoline | Ki | 47.86 [1] |
 | (3R,3As)-7,8-dimethoxy-3-[[4-[(E)-2-methyl-3-phenylprop-2-enyl]piperazin-1-yl]methyl]-3a,4-dihydro-3H-chromeno[4,3-c][1,2]oxazole | Ki | 0.3 [1], 0.8 [2] |
 | (3R,3As)-7,8-dimethoxy-3-[[4-[(E)-3-phenylbut-2-enyl]piperazin-1-yl]methyl]-3a,4-dihydro-3H-chromeno[4,3-c][1,2]oxazole | Ki | 0.3 [1], 1.4 [2] |
 | Risperidone | Ki | 3.63 [1], 10.0 [2], 1000.0 [3] |
 | Olanzapine | Ki | 192.0 [1], 203.0 [2], 1000.0 [3] |
 | Prazosin | Ki | 210.0 [1], 989.0 [2], 2133.0 [3] |
 | Mianserin | IC50 | 20.89 [1] |
| Mianserin | Ki | 4.8 [1], 16.0 [2] |
 | Brimonidine | Ki | 2.7 [1], 6.76 [2], 112.0 [3] |
 | Oxymetazoline | Ki | 0.29 [1], 8.64 [2], 16.22 [3] |
 | Rilmenidine | Ki | 36.31 [1], 181.97 [2], 300.0 [3] |
 | Atipamezole | Ki | 1.2 [1], 1.86 [2], 3.16 [3] |
 | N,N-Dimethyl-1-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl)methanamine | IC50 | 371.54 [1] |
 | 3-[2-[1-(4,5-Dihydro-1H-imidazol-2-yl)ethoxy]phenyl]phenol | Ki | 27.54 [1] |
 | 2-[1-[2-(3-Nitrophenyl)phenoxy]ethyl]-4,5-dihydro-1H-imidazole | Ki | 60.26 [1] |
 | (3R,3As)-7,8-dimethoxy-3-[[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]methyl]-3a,4-dihydro-3H-chromeno[4,3-c][1,2]oxazole | Ki | 2.6 [1], 8.8 [2], 25.0 [3] |
 | 2-[(1S)-1-(2-Prop-2-enylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 52.48 [1] |
 | 2-[(1R)-1-(2-Prop-2-enylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 100.0 [1] |
 | 2-[1-[2-(Cyclopropylmethyl)phenoxy]ethyl]-4,5-dihydro-1H-imidazole | Ki | 36.31 [1] |
 | Unii-G7fms28pyd | IC50 | 1100.0 [1] |
| Unii-G7fms28pyd | Ki | 411.0 [1] |
 | N-(4,5-Dihydro-1H-imidazol-2-yl)-5-methylquinoxalin-6-amine | Ki | 2.0 [1], 7.24 [2] |
 | (3R,3As)-7,8-dimethoxy-3-[[4-(naphthalen-2-ylmethyl)piperazin-1-yl]methyl]-3a,4-dihydro-3H-chromeno[4,3-c][1,2]oxazole | Ki | 1.3 [1], 5.0 [2] |
 | Epinephrine | Ki | 160.0 [1], 276.0 [2] |
 | Quetiapine | Ki | 934.3 [1], 1000.0 [2] |
 | Mirtazapine | IC50 | 85.11 [1] |
| Mirtazapine | Ki | 20.0 [1] |
 | Tamsulosin | Ki | 13.4 [1], 63.0 [2] |
 | Clemastine | Ki | 69.0 [1], 169.82 [2] |
 | Cirazoline | Ki | 58.88 [1] |
 | Niguldipine | Ki | 530.0 [1], 645.0 [2] |
 | Unii-22xbk6DY1E | Ki | 114.0 [1] |
 | N,N-Diallyl-5-methoxytryptamine | Ki | 213.8 [1], 10000.0 [2] |
 | ATC-0175 free base | IC50 | 104.0 [1], 260.0 [2] |
 | 1H-Imidazole, 4,5-dihydro-2-(1-phenoxyethyl)- | Ki | 26.92 [1] |
 | Ethanesulfonamide, N-(3-(1H-imidazol-4-ylmethyl)phenyl)- | Ki | 169.82 [1] |
 | 2-(1-Benzofuran-6-yl)-N-[[(1R)-5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl]methyl]-N-methylethanamine | Ki | 2.4 [1], 2.5 [2] |
 | 2-[(1S)-1-(2-Phenylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 91.2 [1] |
 | 4-(5-Fluoro-2-indanylmethyl)-2-imidazoline | Ki | 5.9 [1] |
 | 5-N-[3-(4,4-Diphenylpiperidin-1-yl)propyl]-3-N,2,6-trimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxamide | Ki | 398.0 [1], 398.11 [2] |
 | 2-[(1R)-1-(2-Phenylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 186.21 [1] |
 | 5-N-[3-(4,4-Diphenylpiperidin-1-yl)propyl]-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxamide | Ki | 148.0 [1], 371.54 [2] |
 | 1-(17-Chloro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)-N,N-dimethylmethanamine | IC50 | 478.63 [1] |
 | 1-Benzyl-4-chroman-2-ylmethyl-piperazine | Ki | 146.1 [1], 167.0 [2] |
 | 4-Bromo-N-[4-[[4-(dimethylamino)quinazolin-2-yl]amino]cyclohexyl]-2-(trifluoromethoxy)benzenesulfonamide | IC50 | 47.0 [1], 57.0 [2] |
 | 2-[1-[2-(3-Fluorophenyl)phenoxy]ethyl]-4,5-dihydro-1H-imidazole | Ki | 14.79 [1] |
 | 3-[2-[1-(4,5-Dihydro-1H-imidazol-2-yl)ethoxy]phenyl]pyridine | Ki | 138.04 [1] |
 | 4-Bromo-N-[[4-[[4-(dimethylamino)quinazolin-2-yl]amino]cyclohexyl]methyl]-2-(trifluoromethoxy)benzenesulfonamide | IC50 | 110.0 [1], 130.0 [2] |
 | 2-N-[1-[4-Bromo-2-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-yl]-4-N,4-N-dimethylquinazoline-2,4-diamine | IC50 | 170.0 [1] |
 | 2-[1-(2-Thiophen-3-ylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 45.71 [1] |
 | (3R,3As)-3-[[4-[(E)-3-(4-fluorophenyl)-2-methylprop-2-enyl]piperazin-1-yl]methyl]-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c][1,2]oxazole | Ki | 3.4 [1] |
 | (R)-3-Nitrobiphenyline | Ki | 81.28 [1] |
 | 2-[(1S)-1-[2-(3-Nitrophenyl)phenoxy]ethyl]-4,5-dihydro-1H-imidazole | Ki | 72.44 [1] |
 | (3R,3As)-7,8-dimethoxy-3-[[4-[(Z)-3-phenylprop-2-enyl]piperazin-1-yl]methyl]-3a,4-dihydro-3H-chromeno[4,3-c][1,2]oxazole | Ki | 23.0 [1] |
 | 2-[1-(2-Cyclopropylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 22.91 [1] |
 | 2-[(1S)-1-(2-Cyclopropylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 20.89 [1] |
 | 2-[(1R)-1-(2-Cyclopropylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 44.67 [1] |
 | (8S)-N-[2-(3-Fluorophenyl)ethyl]pentacyclo[5.4.0.02,6.03,10.05,9]undecan-8-amine | Ki | 7609.0 [1] |
 | 2-(1-(2-Bromophenoxy)ethyl)-4,5-dihydro-1H-imidazole | Ki | 22.91 [1] |
 | 2-[1-(2-Cyclopropyloxyphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 83.18 [1] |
 | 2-[(1R)-1-[2-(Cyclopropylmethyl)phenoxy]ethyl]-4,5-dihydro-1H-imidazole | Ki | 44.67 [1] |
 | 2-[(1S)-1-[2-(Cyclopropylmethyl)phenoxy]ethyl]-4,5-dihydro-1H-imidazole | Ki | 41.69 [1] |
 | 5-Methyl-1,5-diazapentacyclo[10.8.1.02,7.08,21.013,18]henicosa-2(7),8(21),9,11,13,15,17-heptaene | Ki | 407.0 [1], 407.38 [2] |
 | 5-O-[3-(4,4-Diphenylpiperidin-1-yl)propyl] 3-O-methyl 2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate | Ki | 800.0 [1], 1023.0 [2] |
 | N-[2-[4-[[(3S)-2,3-Dihydro-1,4-benzodioxin-3-yl]methyl]-1,4-diazepan-1-yl]ethyl]-2-phenoxypyridine-3-carboxamide | Ki | 94.4 [1], 442.0 [2] |
 | 1-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-(2-methoxyphenyl)piperazine | Ki | 167.0 [1], 506.0 [2] |
 | N-[2-[4-(2,3-Dihydro-1,4-benzodioxin-3-ylmethyl)-1,4-diazepan-1-yl]ethyl]-2-phenoxypyridine-3-carboxamide | Ki | 220.0 [1], 474.0 [2] |
 | 2-(3-Cyanophenoxy)-N-[2-[4-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1,4-diazepan-1-yl]ethyl]pyridine-3-carboxamide | Ki | 208.0 [1], 501.0 [2] |
 | 2-(Tert-butylamino)-N-[2-[4-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1,4-diazepan-1-yl]ethyl]pyridine-3-carboxamide | Ki | 138.0 [1], 366.0 [2] |
 | 2-Butoxy-N-[2-[4-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1,4-diazepan-1-yl]ethyl]pyridine-3-carboxamide | Ki | 73.6 [1], 81.0 [2] |
 | 6-Butoxy-N-[2-[4-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1,4-diazepan-1-yl]ethyl]pyridine-2-carboxamide | Ki | 48.4 [1], 118.0 [2] |
 | 1-(2,3-Dihydro-1,4-benzodioxin-3-ylmethyl)-4-[2-[(2-phenoxypyridin-3-yl)methoxy]ethyl]-1,4-diazepane | Ki | 66.1 [1], 275.0 [2] |
 | 5-[[4-(2,3-Dihydro-1,4-benzodioxin-3-ylmethyl)-1,4-diazepan-1-yl]methyl]-3-(2-phenoxypyridin-3-yl)-1,2,4-oxadiazole | Ki | 15.4 [1], 44.8 [2] |
 | 4-Bromo-N-[[4-[[[4-(dimethylamino)quinazolin-2-yl]amino]methyl]cyclohexyl]methyl]-2-(trifluoromethoxy)benzenesulfonamide | IC50 | 7.7 [1] |
 | Norepinephrine | Ki | 66.0 [1] |
 | Propranolol | IC50 | 5011.87 [1] |
 | Vancomycin | Ki | 50.12 [1] |
 | Verapamil | Ki | 217.0 [1] |
 | Tamoxifen | Ki | 726.0 [1] |
 | Chlorpromazine | Ki | 132.0 [1] |
 | Haloperidol | Ki | 1865.0 [1] |
 | Fluoxetine | Ki | 6.31 [1] |
 | Chloroquine | Ki | 4365.16 [1] |
 | Ticlopidine | Ki | 143.0 [1] |
 | Clonidine hydrochloride | Ki | 20.89 [1] |
 | Amiodarone | Ki | 117.0 [1] |
 | Amitriptyline | Ki | 132.0 [1] |
 | Ketoconazole | Ki | 7419.0 [1] |
 | Diethylstilbestrol | Ki | 5297.0 [1] |
 | Bromocriptine | Ki | 5.53 [1] |
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