 | Yohimbine | IC50 | 27.1 [1] |
| Yohimbine | Ki | 2.3 [1] |
 | Clonidine | Ki | 9.33 [1], 30.0 [2], 56.23 [3], 160.0 [4] |
 | Terazosin | Ki | 78.0 [1], 170.0 [2], 213.0 [3], 223.87 [4], 878.0 [5] |
 | (3R,3As)-7,8-dimethoxy-3-[[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]methyl]-3a,4-dihydro-3H-chromeno[4,3-c][1,2]oxazole | Ki | 0.5 [1], 4.8 [2], 6.2 [3], 8.8 [4] |
 | Mianserin | IC50 | 42.66 [1] |
| Mianserin | Ki | 3.8 [1], 26.0 [2] |
 | Idazoxan | IC50 | 53.7 [1] |
| Idazoxan | Ki | 17.78 [1], 19.0 [2] |
 | 2-[1-(2-Prop-2-enylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 85.11 [1] |
 | Methyl 5-[3-(4,4-diphenylpiperidin-1-yl)propylcarbamoyl]-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3-carboxylate | Ki | 370.0 [1], 371.54 [2], 912.0 [3], 1320.0 [4] |
 | 2-[1-(2-Biphenylyloxy)ethyl]-2-imidazoline | Ki | 199.53 [1] |
 | (3R,3As)-7,8-dimethoxy-3-[[4-[(E)-2-methyl-3-phenylprop-2-enyl]piperazin-1-yl]methyl]-3a,4-dihydro-3H-chromeno[4,3-c][1,2]oxazole | Ki | 0.1 [1], 0.2 [2] |
 | (3R,3As)-7,8-dimethoxy-3-[[4-[(E)-3-phenylbut-2-enyl]piperazin-1-yl]methyl]-3a,4-dihydro-3H-chromeno[4,3-c][1,2]oxazole | Ki | 0.2 [1], 0.6 [2] |
 | Clozapine | Ki | 1.14 [1], 2.9 [2], 100.0 [3] |
 | Risperidone | Ki | 1.39 [1], 3.2 [2], 10.0 [3] |
 | Olanzapine | Ki | 77.0 [1], 82.0 [2], 100.0 [3] |
 | Prazosin | Ki | 24.0 [1], 94.0 [2], 95.0 [3] |
 | Phentolamine | Ki | 8.4 [1], 16.0 [2], 80.3 [3] |
 | Oxymetazoline | Ki | 1.0 [1], 58.88 [2], 383.0 [3] |
 | 3-[2-[1-(4,5-Dihydro-1H-imidazol-2-yl)ethoxy]phenyl]phenol | Ki | 17.78 [1] |
 | 2-[1-[2-(3-Nitrophenyl)phenoxy]ethyl]-4,5-dihydro-1H-imidazole | Ki | 234.42 [1] |
 | 2-[(1S)-1-(2-Prop-2-enylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 70.79 [1] |
 | 2-[(1R)-1-(2-Prop-2-enylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 177.83 [1] |
 | 2-[1-[2-(Cyclopropylmethyl)phenoxy]ethyl]-4,5-dihydro-1H-imidazole | Ki | 275.42 [1] |
 | N-(4,5-Dihydro-1H-imidazol-2-yl)-5-methylquinoxalin-6-amine | Ki | 27.0 [1], 28.18 [2] |
 | (3R,3As)-7,8-dimethoxy-3-[[4-(naphthalen-2-ylmethyl)piperazin-1-yl]methyl]-3a,4-dihydro-3H-chromeno[4,3-c][1,2]oxazole | Ki | 0.8 [1], 3.1 [2] |
 | Quetiapine | Ki | 61.1 [1], 100.0 [2] |
 | Rauwolscine | IC50 | 16.0 [1] |
| Rauwolscine | Ki | 1.0 [1] |
 | Mirtazapine | IC50 | 199.53 [1] |
| Mirtazapine | Ki | 18.0 [1] |
 | Brimonidine | Ki | 44.0 [1], 83.18 [2] |
 | Rilmenidine | Ki | 12.59 [1], 288.4 [2] |
 | Clemastine | Ki | 14.0 [1], 223.87 [2] |
 | Cirazoline | Ki | 549.54 [1] |
 | Niguldipine | Ki | 330.0 [1], 370.0 [2] |
 | Unii-22xbk6DY1E | Ki | 64.0 [1] |
 | N-(4-(4-Methyl-1-piperazinyl)phenyl)-9-acridinamine | Ki | 27.99 [1], 28.0 [2] |
 | N,N-Diallyl-5-methoxytryptamine | Ki | 501.19 [1], 1479.11 [2] |
 | 2,6,3,5-Ethanediylidenepentaleno(1,6-bc)pyrrol-2(1H)-ol, octahydro-1-(phenylmethyl)- | Ki | 682.0 [1] |
 | 1H-Imidazole, 4,5-dihydro-2-(1-phenoxyethyl)- | Ki | 263.03 [1] |
 | 2-(1-Benzofuran-6-yl)-N-[[(1R)-5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl]methyl]-N-methylethanamine | Ki | 2.1 [1] |
 | 9-Acridinamine, N-(4-(4-ethyl-1-piperazinyl)phenyl)- | Ki | 36.98 [1], 37.0 [2] |
 | [4-(4-Methylpiperazinyl)phenyl]-4-quinolylamine | Ki | 1698.24 [1], 1700.0 [2] |
 | 2-[(1S)-1-(2-Phenylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 302.0 [1] |
 | N,N-Dimethyl-1-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl)methanamine | IC50 | 1862.09 [1] |
 | 4-(5-Fluoro-2-indanylmethyl)-2-imidazoline | Ki | 19.0 [1] |
 | 5-N-[3-(4,4-Diphenylpiperidin-1-yl)propyl]-3-N,2,6-trimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxamide | Ki | 323.0 [1], 323.59 [2] |
 | 2-[(1R)-1-(2-Phenylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 977.24 [1] |
 | 5-N-[3-(4,4-Diphenylpiperidin-1-yl)propyl]-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxamide | Ki | 165.0 [1], 323.59 [2] |
 | [4-(3,4-Dimethylpiperazin-1-yl)phenyl]-(2,3,7-trimethylquinolin-4-yl)amine | Ki | 15.0 [1] |
 | {4-[4-(3,4-Dimethylpiperazin-1-yl)phenylamino]-2-methylquinolin-3-yl}methanol | Ki | 7.5 [1] |
 | N-[4-(1,3,4,6,7,8,9,9a-Octahydropyrido[1,2-a]pyrazin-2-yl)phenyl]-2,3-dimethylquinolin-4-amine | Ki | 2.3 [1] |
 | [4-(3,4-Dimethylpiperazin-1-yl)phenyl]-(2-methyl-3-phenylquinolin-4-yl)amine | Ki | 5.0 [1] |
 | (3-Ethyl-2-methylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)-phenyl]amine | Ki | 25.0 [1] |
 | (2,3-Dimethylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)phenyl] amine | Ki | 34.99 [1], 35.0 [2] |
 | (3-Isopropyl-2-methylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)phenyl]amine | Ki | 52.0 [1] |
 | {7-Chloro-4-[4-(3,3,4-trimethylpiperazin-1-yl)phenylamino]-quinolin-3-yl}methanol | Ki | 5.9 [1] |
 | {4-[4-(3,4-Dimethylpiperazin-1-yl)phenylamino]-6-fluoroquinolin-3-yl}methanol | Ki | 42.95 [1], 43.0 [2] |
 | 7-Chloro-N-[4-(3,4-dimethylpiperazin-1-yl)phenyl]-2,3-dimethylquinolin-4-amine | Ki | 8.3 [1] |
 | (2-Methyl-3-phenylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)-phenyl]amine | Ki | 34.99 [1], 35.0 [2] |
 | [4-(3,4-Dimethylpiperazin-1-yl)phenyl]-(2,3,7,8-tetramethylquinolin-4-yl)amine | Ki | 5.0 [1] |
 | (3-Methylquinolin-4-yl)-[4-(3,3,4-trimethylpiperazin-1-yl)phenyl]amine | Ki | 5.39 [1], 5.4 [2] |
 | {4-[4-(3,3,4-Trimethylpiperazin-1-yl)phenylamino]quinolin-3-yl}methanol | Ki | 6.4 [1] |
 | {6-Fluoro-4-[4-(3,3,4-trimethylpiperazin-1-yl)phenylamino]-quinolin-3-yl}methanol | Ki | 50.0 [1] |
 | 1-Benzyl-4-chroman-2-ylmethyl-piperazine | Ki | 19.6 [1], 21.1 [2] |
 | 2-[1-[2-(3-Fluorophenyl)phenoxy]ethyl]-4,5-dihydro-1H-imidazole | Ki | 16.98 [1] |
 | 3-[2-[1-(4,5-Dihydro-1H-imidazol-2-yl)ethoxy]phenyl]pyridine | Ki | 64.57 [1] |
 | 2-[1-(2-Thiophen-3-ylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 131.83 [1] |
 | [4-(3,4-Dimethylpiperazin-1-yl)phenyl]-(2,3,5,7-tetramethylquinolin-4-yl)amine | Ki | 132.0 [1], 132.13 [2] |
 | N-[4-[(3S)-3,4-Dimethylpiperazin-1-yl]phenyl]-2,3,7,8-tetramethylquinolin-4-amine | Ki | 83.95 [1], 84.0 [2] |
 | N-[4-[(3R)-3,4-Dimethylpiperazin-1-yl]phenyl]-2,3,7-trimethylquinolin-4-amine | Ki | 8.3 [1] |
 | N-[4-(3,4-Dimethylpiperazin-1-yl)phenyl]-2,3,8-trimethylquinolin-4-amine | Ki | 6.9 [1] |
 | N-[4-(3,4-Dimethylpiperazin-1-yl)phenyl]-2,3,5,8-tetramethylquinolin-4-amine | Ki | 389.94 [1], 390.0 [2] |
 | (5-Chloro-2,3-dimethylquinolin-4-yl)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]amine | Ki | 134.9 [1], 135.0 [2] |
 | 2,3,8-Trimethyl-N-[4-(3-methyl-1,3-diazinan-1-yl)phenyl]quinolin-4-amine | Ki | 770.0 [1], 5000.35 [2] |
 | 4-N-(2,3-Dimethylquinolin-4-yl)-1-N-(2-pyrrolidin-1-ylethyl)benzene-1,4-diamine | Ki | 100.0 [1] |
 | [4-[4-[(3R)-3,4-Dimethylpiperazin-1-yl]anilino]-3-methylquinolin-2-yl]methanol | Ki | 8.99 [1], 9.0 [2] |
 | (R)-{4-[4-(3,4-Dimethylpiperazin-1-yl)phenylamino]quinolin-3-yl}methanol | Ki | 9.2 [1] |
 | (3-Benzyl-2-methylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)-phenyl]amine | Ki | 34.99 [1], 35.0 [2] |
 | [4-(3,4-Dimethylpiperazin-1-yl)phenyl]-(3-methylquinolin-4-yl)amine | Ki | 8.49 [1], 8.5 [2] |
 | N-[4-[(3R)-3,4-Dimethylpiperazin-1-yl]phenyl]-2,3,7,8-tetramethylquinolin-4-amine | Ki | 7.69 [1], 7.7 [2] |
 | N-[4-[(3S)-3,4-Dimethylpiperazin-1-yl]phenyl]-2,3,7-trimethylquinolin-4-amine | Ki | 76.0 [1], 76.03 [2] |
 | [4-(3,4-Dimethylpiperazin-1-yl)phenyl]-(2,3,5-trimethylquinolin-4-yl)amine | Ki | 87.0 [1], 87.1 [2] |
 | N-[4-(3,4-Dimethylpiperazin-1-yl)phenyl]-6-fluoro-2,3-dimethylquinolin-4-amine | Ki | 16.0 [1] |
 | 1-N-[2-(Diethylamino)ethyl]-4-N-(3-ethyl-2,8-dimethylquinolin-4-yl)benzene-1,4-diamine | Ki | 82.0 [1], 82.04 [2] |
 | (3-Ethyl-2,8-dimethylquinolin-4-yl)-[4-(4-methyl-[1,4]diazepan-1-yl)phenyl]amine | Ki | 8.49 [1], 8.5 [2] |
 | [2-Methyl-4-[4-(3,3,4-trimethylpiperazin-1-yl)anilino]quinolin-3-yl]methanol | Ki | 3.8 [1] |
 | 1-[4-[4-(3,4-Dimethylpiperazin-1-yl)anilino]-2-methylquinolin-3-yl]ethanol | Ki | 4.9 [1] |
 | (R)-{4-[4-(3-Methylpiperazin-1-yl)phenylamino]quinolin-3-yl}methanol | Ki | 205.0 [1], 205.12 [2] |
 | [4-[4-[(3R)-3,4-Dimethylpiperazin-1-yl]anilino]-6-fluoroquinolin-3-yl]methanol | Ki | 38.0 [1], 38.02 [2] |
 | (3,5-Dimethyl-pyridin-4-yl)-[4-(4-methylpiperazin-1-yl)phenyl]amine | Ki | 769.13 [1], 5000.0 [2] |
 | N-[4-(3,4-Dimethylpiperazin-1-yl)phenyl]-3-ethyl-2-methyl-5,6,7,8-tetrahydroquinolin-4-amine | Ki | 109.9 [1], 110.0 [2] |
 | (3R,3As)-3-[[4-[(E)-3-(4-fluorophenyl)-2-methylprop-2-enyl]piperazin-1-yl]methyl]-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c][1,2]oxazole | Ki | 0.7 [1] |
 | (R)-3-Nitrobiphenyline | Ki | 257.04 [1], 363.08 [2] |
 | 2-[(1S)-1-[2-(3-Nitrophenyl)phenoxy]ethyl]-4,5-dihydro-1H-imidazole | Ki | 537.03 [1] |
 | (3R,3As)-7,8-dimethoxy-3-[[4-[(Z)-3-phenylprop-2-enyl]piperazin-1-yl]methyl]-3a,4-dihydro-3H-chromeno[4,3-c][1,2]oxazole | Ki | 9.5 [1] |
 | 2-[1-(2-Cyclopropylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 79.43 [1] |
 | 2-[(1S)-1-(2-Cyclopropylphenoxy)ethyl]-4,5-dihydro-1H-imidazole | Ki | 63.1 [1] |
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