Amiloride-sensitive cation channel 3 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Amiloride	IC50	4400.0 [1]
	Benzo[b]thiophen-2-ylmethanamine	IC50	97000.0 [1]
	1,3-Benzothiazol-2-ylmethylamine	IC50	363000.0 [1]
	2-Amino-6-phenylpyridine	IC50	763000.0 [1]
	(3-Methoxy-pyridin-2-yl)-(6-methyl-pyridin-2-yl)-amine	IC50	190000.0 [1]
	6-(2-Phenylethynyl)naphthalene-2-carboxamidine	IC50	6300.0 [1]
	6-Phenylpyrimidin-4-amine	IC50	130000.0 [1]
	CID 11160454	IC50	9000.0 [1]
	6-Bromo-1,2,3,4-tetrahydroisoquinoline	IC50	701000.0 [1]
	6-(3,5-Dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline	IC50	3300.0 [1]
	2-(3,5-Dichlorophenyl)-1H-indole-5-carboximidamide	IC50	133000.0 [1]
	2-(3-Amino-5-chlorophenyl)-1H-indole-5-carboximidamide	IC50	95000.0 [1]
	2-(3-Fluoro-5-methoxyphenyl)-1H-indole-5-carboximidamide	IC50	374000.0 [1]
	2-(3-(Benzylamino)-5-chlorophenyl)-1H-indole-5-carboximidamide	IC50	77000.0 [1]
	2-Phenylpyridin-4-amine	IC50	6900.0 [1]
	(4-(1H-Imidazol-4-YL)phenyl)methanamine	IC50	160000.0 [1]
	3-Amino-5-(biphenyl-3-yl)-N-(diaminomethylene)pyrazine-2-carboxamide	IC50	490.0 [1]
	2-Phenyl-1H-indole-5-carboximidamide	IC50	2765000.0 [1]
	3-Amino-6-chloro-N-(diaminomethylene)-5-(naphthalen-2-ylamino)pyrazine-2-carboxamide	IC50	510.0 [1]
	3-Amino-N-(diaminomethylene)-5-(3-(thiophen-3-yl)phenyl)pyrazine-2-carboxamide	IC50	640.0 [1]
	2-(2,3,5-Trichlorophenyl)-1H-indole-5-carboximidamide	IC50	135000.0 [1]
	2-(3-Chloro-5-fluorophenyl)-1H-indole-5-carboximidamide	IC50	278000.0 [1]
	2-(2,6-Dichloropyridin-4-yl)-1H-indole-5-carboximidamide	IC50	291000.0 [1]
	2-(3,5-Dibromophenyl)-1H-indole-5-carboximidamide	IC50	59000.0 [1]
	2-(3-Chloro-5-((phenylamino)methyl)phenyl)-1H-indole-5-carboximidamide	IC50	114000.0 [1]
	2-(3,5-Dichloro-4-cyanophenyl)-1H-indole-5-carboximidamide	IC50	272000.0 [1]
	2-(3-Bromo-5-fluorophenyl)-1H-indole-5-carboximidamide	IC50	59000.0 [1]
	2-(3-Chloro-5-methylphenyl)-1H-indole-5-carboximidamide	IC50	51000.0 [1]
	6-Methyl-N-[4-(6-piperazin-1-ylpyridin-3-yl)phenyl]pyridin-2-amine	IC50	3800.0 [1]
	6-[4-(4-Methylpiperazin-1-yl)-3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydroisoquinoline	IC50	3100.0 [1]
	[3-Chloro-6-[2-(1,2,3,4-tetrahydroisoquinolin-7-yl)ethynyl]-1-benzothiophen-2-yl]methanamine	IC50	220.0 [1]
	6-Bromo-2-[(5-methoxy-1H-indol-3-yl)methyl]-3,4-dihydro-1H-isoquinoline	IC50	10900.0 [1]
	6-[6-(2-Methylpiperidin-1-yl)pyridin-2-yl]-1,2,3,4-tetrahydroisoquinoline	IC50	1700.0 [1]
	4-(6-Bromo-3,4-dihydroisoquinolin-2(1H)-yl)-2-methylquinoline	IC50	27600.0 [1]
	6-(3-(Trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline	IC50	7100.0 [1]
	2-[(5-Methoxy-1H-indol-3-yl)methyl]-6-[3-(trifluoromethyl)phenyl]-3,4-dihydro-1H-isoquinoline	IC50	103000.0 [1]
	2-Methyl-4-(4-(6-methylpyridin-2-ylamino)phenyl)but-3-yn-2-ol	IC50	17000.0 [1]
	4-Amino-N-[2-(4-chlorophenyl)ethyl]-2-propylquinoline-6-carboxamide	IC50	9600.0 [1]
	6-(4-(4-Methylpiperazin-1-yl)phenyl)-1,2,3,4-tetrahydroisoquinoline	IC50	14400.0 [1]
	2-Phenyl-6-(pyridin-2-ylmethyl)pyridin-4-amine	IC50	5800.0 [1]
	CID 54586726	IC50	19400.0 [1]
	4-(3-(4-Aminopyridin-2-yl)phenyl)but-3-yn-1-ol	IC50	2600.0 [1]
	2-(3-(Phenylethynyl)phenyl)pyridin-4-amine	IC50	1200.0 [1]
	Tert-butyl 7-[2-[2-(aminomethyl)-3-chloro-1-benzothiophen-6-yl]ethynyl]-3,4-dihydro-1H-isoquinoline-2-carboxylate	IC50	50000.0 [1]
	[3-Chloro-6-[2-[2-(2,2,2-trifluoroethyl)-3,4-dihydro-1H-isoquinolin-7-yl]ethynyl]-1-benzothiophen-2-yl]methanamine	IC50	50000.0 [1]
	[3-Chloro-6-[2-(5-pyrrolidin-1-yl-5,6,7,8-tetrahydronaphthalen-1-yl)ethynyl]-1-benzothiophen-2-yl]methanamine	IC50	2500.0 [1]
	[6-[2-(2-Benzyl-3,4-dihydro-1H-isoquinolin-7-yl)ethynyl]-3-chloro-1-benzothiophen-2-yl]methanamine	IC50	17100.0 [1]
	6-[2-(2-Methyl-1-propan-2-yl-3,4-dihydro-1H-isoquinolin-7-yl)ethynyl]naphthalene-2-carboximidamide	IC50	460.0 [1]
	[6-(2-Phenylethynyl)naphthalen-2-yl]methanamine	IC50	4800.0 [1]
	5-[2-[2-(Aminomethyl)-3-chloro-1-benzothiophen-6-yl]ethynyl]-N,N-diethyl-3,4-dihydro-2H-quinolin-1-amine	IC50	510.0 [1]
	[3-Chloro-6-[2-(2-ethyl-3,4-dihydro-1H-isoquinolin-7-yl)ethynyl]-1-benzothiophen-2-yl]methanamine	IC50	230.0 [1]
	[3-Chloro-6-[2-[2-(2,2-difluoroethyl)-3,4-dihydro-1H-isoquinolin-7-yl]ethynyl]-1-benzothiophen-2-yl]methanamine	IC50	10200.0 [1]
	[3-Chloro-6-[2-(2-propan-2-yl-3,4-dihydro-1H-isoquinolin-7-yl)ethynyl]-1-benzothiophen-2-yl]methanamine	IC50	310.0 [1]
	5-[2-[2-(Aminomethyl)-3-chloro-1-benzothiophen-6-yl]ethynyl]-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-1-amine	IC50	230.0 [1]
	4-[2-[2-(Aminomethyl)-3-chloro-1-benzothiophen-6-yl]ethynyl]-N,N-dimethyl-2,3-dihydro-1H-inden-1-amine	IC50	190.0 [1]
	[3-Chloro-6-(2-phenylethynyl)-1-benzothiophen-2-yl]methanamine	IC50	2800.0 [1]
	[3-Chloro-6-[2-(1,2-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)ethynyl]-1-benzothiophen-2-yl]methanamine	IC50	270.0 [1]
	[3-Chloro-6-[2-(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)ethynyl]-1-benzothiophen-2-yl]methanamine	IC50	680.0 [1]
	3-Chloro-6-(2-phenylethynyl)-1-benzothiophene-2-carboximidamide	IC50	3400.0 [1]
	1-[3-[2-[2-(Aminomethyl)-3-chloro-1-benzothiophen-6-yl]ethynyl]phenyl]-N,N-dimethylethanamine	IC50	4300.0 [1]
	4-(1H-Imidazol-4-yl)aniline	IC50	430000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 61 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Amiloride-sensitive cation channel 3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/amiloride-sensitive-cation-channel-3-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 8). Quest Database™ Amiloride-sensitive cation channel 3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/amiloride-sensitive-cation-channel-3-inhibitors-ic50-ki.
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