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Angiotensin-converting enzyme Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
CaptoprilIC5020.0 [1]
CaptoprilKi2.0 [1]
EnalaprilatIC502.4 [1]
LisinoprilIC501.2 [1]
LisinoprilKi51.0 [1], 131.5 [2]
EnalaprilIC50140.0 [1]
KetoaceIC5012.0 [1]
KetoaceKi45200.0 [1]
(2S)-3-(4-Hydroxyphenyl)-2-[[(2R)-2-[[hydroxy-[(1R)-2-phenyl-1-(phenylmethoxycarbonylamino)ethyl]phosphoryl]methyl]-3-(3-phenyl-1,2-oxazol-5-yl)propanoyl]amino]propanoic acidKi4.0 [1]
OmapatrilatIC501.0 [1], 2.0 [2]
OmapatrilatKi0.01 [1], 0.02 [2], 6.0 [3]
(2S)-2-[[(2R)-2-[[Hydroxy-[(1R)-2-phenyl-1-(phenylmethoxycarbonylamino)ethyl]phosphoryl]methyl]-3-(3-phenyl-1,2-oxazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoic acidKi3.6 [1], 36.0 [2], 500.0 [3], 1510.0 [4], 1520.0 [5]
(2S)-2-[[(2R)-2-[[Hydroxy-[(1R)-2-phenyl-1-(phenylmethoxycarbonylamino)ethyl]phosphoryl]methyl]-3-(3-phenyl-1,2-oxazol-5-yl)propanoyl]amino]-3-phenylpropanoic acidKi3.8 [1], 32.0 [2], 110.0 [3], 340.0 [4]
QuinaprilIC508.3 [1]
L-Alanyl-L-prolineIC5042000.0 [1], 110000.0 [2], 229086.77 [3]
L-Alanyl-L-prolineKi50000.0 [1]
(4S,7S,10As)-4-[[(2S)-2-[[(2S)-1-[[(4S,7S,10aS)-7-carboxy-5-oxo-2,3,4,7,8,9,10,10a-octahydropyrido[2,1-b][1,3]thiazepin-4-yl]amino]-1-oxo-3-phenylpropan-2-yl]disulfanyl]-3-phenylpropanoyl]amino]-5-oxo-2,3,4,7,8,9,10,10a-octahydropyrido[2,1-b][1,3]thiazepine-7-carboxylic acidIC501800.0 [1], 2100.0 [2], 2200.0 [3], 2800.0 [4]
QuinaprilatIC502.8 [1], 2.9 [2], 280.0 [3]
Val-trpIC501584.89 [1], 1600.0 [2], 1700.0 [3]
(2S)-1-[(2S)-3-[[(1R)-1-Benzamido-2-phenylethyl]-dihydroxysilyl]-2-methylpropanoyl]pyrrolidine-2-carboxylic acidIC503.8 [1]
2-[(3S)-2-Oxo-3-[[(2S)-3-phenyl-2-sulfanylpropanoyl]amino]-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acidIC5012.0 [1]
ThiorphanIC50140.0 [1], 316.23 [2]
(2-Mercaptomethyl-3-phenyl-propionyl)-glycineIC50140.0 [1], 860.0 [2]
MoexiprilIC502.6 [1], 56.0 [2]
Glycyl-L-prolineIC50446683.59 [1]
Glycyl-L-phenylalanineIC50602559.59 [1], 630957.34 [2]
4-Thiazolidinecarboxylic acid, 2-(2-hydroxyphenyl)-3-(3-mercapto-1-oxopropyl)-IC5019.95 [1], 65.0 [2]
NorathyriolIC50530800.0 [1]
NorathyriolKi250200.0 [1]
Benzoylphenylalanyl-alanyl-prolineIC503.2 [1], 2700.0 [2]
Val-proIC50416869.38 [1]
CID 9827219Ki7.0 [1], 7500.0 [2]
3,4,5,6-TetrahydroxyxanthoneIC50238500.0 [1]
3,4,5,6-TetrahydroxyxanthoneKi126000.0 [1]
1,3,5,6-TetrahydroxyxanthoneIC5069200.0 [1]
1,3,5,6-TetrahydroxyxanthoneKi34200.0 [1]
Isoleucyl-TyrosineIC503700.0 [1], 3715.35 [2]
SuccinylprolineIC5014500.0 [1], 33113.11 [2]
N(alpha)-PhosphorylalanylprolineIC50776.25 [1]
N(alpha)-PhosphorylalanylprolineKi1.4 [1]
L-Proline, 1-(3-mercapto-1-oxopropyl)-IC5016982.44 [1], 1800000.0 [2]
1-(3-Mercaptopropanoyl)-6-methylpiperidine-2-carboxylic acidIC501.0 [1], 20.0 [2]
S-[3-(Benzylamino)-2-methyl-3-oxopropyl] ethanethioateIC50200000.0 [1], 500000.0 [2]
N-Benzoylphenylalanyl-glycyl-prolineIC509400.0 [1]
5-BmoppIC501.0 [1]
(2S)-1-[(2R)-2-Methyl-3-sulfanylpropanoyl]-2,3-dihydroindole-2-carboxylic acidIC503.7 [1], 6.03 [2]
(2S)-1-[(2S)-2-[[(2S)-3-Phenyl-2-sulfanylpropanoyl]amino]propanoyl]pyrrolidine-2-carboxylic acidIC5030.0 [1]
(3R,6S)-4-Oxo-3-(sulfanylmethyl)-5-azabicyclo[10.4.0]hexadeca-1(16),12,14-triene-6-carboxylic acidIC502000.0 [1], 8000.0 [2]
1-(5-Benzoylamino-4-oxo-6-phenyl-hexanoyl)-pyrrolidine-2-carboxylic acidIC5070.0 [1]
1-(5-Benzoylamino-4-oxo-6-phenyl-hexanoyl)-pyrrolidine-2-carboxylic acidKi100.0 [1]
S-(3-Anilino-2-methyl-3-oxopropyl) ethanethioateIC50300.0 [1], 2000.0 [2]
1-(5-Benzoylamino-2-methyl-4-oxo-6-phenyl-hexanoyl)-pyrrolidine-2-carboxylic acidIC503.02 [1], 8.2 [2]
1-(3-Mercapto-propionyl)-(R)-pyrrolidine-2-carboxylic acidIC50200.0 [1], 1819700.86 [2]
1-(4-Carboxy-2-methyl-butyryl)-pyrrolidine-2-carboxylic acidIC504897.79 [1], 4900.0 [2]
L-Proline, 1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]-5-oxo-IC508.91 [1], 9.0 [2]
(S)-1-((1S,5R)-5-Benzoylamino-2-methyl-4-oxo-6-phenyl-hexanoyl)-pyrrolidine-2-carboxylic acidIC503200.0 [1]
Phe-Ala-ProIC501400.0 [1]
2-Oxo-3-[(1-carboxy-3-phenylpropyl)amino]-2,3,4,5-tetrahydro-1H-1-benzazepine-1-acetic acidIC501.7 [1], 10.0 [2]
(3R,6S)-4-Oxo-3-(sulfanylmethyl)-5-azabicyclo[10.3.1]hexadeca-1(15),12(16),13-triene-6-carboxylic acidIC504.0 [1], 1400.0 [2]
(2S)-1-[(2S)-2-[[Hydroxy(2-phenylethyl)phosphoryl]amino]propanoyl]pyrrolidine-2-carboxylic acidIC507.08 [1]
(2S)-1-[(2S)-2-[[Hydroxy(2-phenylethyl)phosphoryl]amino]propanoyl]pyrrolidine-2-carboxylic acidKi0.5 [1]
2-(2-Benzyl-3-mercapto-5-phenyl-pentanoylamino)-propionic acidIC504000.0 [1]
(2S)-1-[(2R)-2-(Carboxymethylamino)propanoyl]pyrrolidine-2-carboxylic acidIC502400.0 [1]
(2S)-1-[(2R)-2-(1-Carboxyethylamino)propanoyl]pyrrolidine-2-carboxylic acidIC5090.0 [1]
CID 44377139IC50688.0 [1]
CID 44377139Ki520.0 [1]
3-(4-Hydroxyphenyl)-2-(2-(3-mercapto-5-methylhexanamido)-3-phenylpropanamido)propanoic acidIC502800.0 [1]
2-(3-Mercapto-5-methylhexanamido)-3-phenylpropanoic acidIC5010000.0 [1]
(2S)-2-[[(2S,3R)-3-Methyl-2-sulfanylpentanoyl]amino]-3-(4-phenylphenyl)propanoic acidKi490.0 [1]
3,4,6,7-TetrahydroxyxanthoneIC5035400.0 [1]
3,4,6,7-TetrahydroxyxanthoneKi14200.0 [1]
2-(1-Carboxymethyl-2-oxo-azonan-3-ylamino)-4-phenyl-butyric acidIC508.1 [1], 1300.0 [2]
2-(1-Carboxymethyl-2-oxo-azepan-3-ylamino)-4-phenyl-butyric acidIC5019.0 [1], 700.0 [2]
[(1R)-1-[[(2S)-2-[[(2S,3S)-2-Acetamido-3-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-2-(4-hydroxyphenyl)ethyl]phosphonic acidIC507.0 [1], 88.0 [2]
N-Acetyl-L-Ile-L-Tyr-(R)-1-Amino-2-(4-Hydroxyphenyl)ethylphosphonic AcidKi11.0 [1], 75.0 [2]
2-(1-Carboxymethyl-2-oxo-azocan-3-ylamino)-4-phenyl-butyric acidIC504.8 [1], 1700.0 [2]
1-[5-[[6-Amino-2-(cyclobutanecarbonylamino)hexanoyl]amino]-4-oxo-6-phenylhexanoyl]pyrrolidine-2-carboxylic acidIC507.0 [1], 7.6 [2]
2-(1-Carboxymethyl-2-oxo-pyrrolidin-3-ylamino)-4-phenyl-butyric acidIC5012000.0 [1], 19000.0 [2]
2-(1-Carboxymethyl-2-oxo-piperidin-3-ylamino)-4-phenyl-butyric acidIC50430.0 [1], 1700.0 [2]
(S)-3-Biphenyl-4-yl-2-((S)-2-mercapto-3-phenyl-propionylamino)-propionic acidIC5080.0 [1]
(S)-3-Biphenyl-4-yl-2-((S)-2-mercapto-3-phenyl-propionylamino)-propionic acidKi30.0 [1]
(2S)-2-[[(1S,2R)-2-[Hydroxy-[(1R)-2-phenyl-1-(phenylmethoxycarbonylamino)ethyl]phosphoryl]cyclopentanecarbonyl]amino]-3-(1H-indol-3-yl)propanoic acidKi3.0 [1], 2500.0 [2]
(2S)-2-[[(1S)-2-[Hydroxy-[(1R)-2-phenyl-1-(phenylmethoxycarbonylamino)ethyl]phosphoryl]cyclopentanecarbonyl]amino]-3-(1H-indol-3-yl)propanoic acidKi3.0 [1], 10000.0 [2]
[(1R)-1-[[(2S)-2-[[(2S,3S)-2-Acetamido-3-methylpentanoyl]amino]-4-methylpentanoyl]amino]-2-(4-hydroxyphenyl)ethyl]phosphonic acidIC5076.0 [1]
[(1R)-1-[[(2S)-2-[[(2S,3S)-2-Acetamido-3-methylpentanoyl]amino]-4-methylpentanoyl]amino]-2-(4-hydroxyphenyl)ethyl]phosphonic acidKi21.0 [1]
Edetic acidIC5014000.0 [1]
ProlineKi86000.0 [1]
LosartanIC5019.0 [1]
Gallic acidIC507700000.0 [1]
RamiprilIC504.0 [1]
DasatinibKi715000.0 [1]
PerindoprilIC501.5 [1]
SitagliptinIC5011000.0 [1]
NovobiocinKi167000.0 [1]
Ellagic acidIC505000000.0 [1]
BenazeprilIC501.7 [1]
TrandolaprilIC500.93 [1]
GlycylglycineIC507244359.6 [1]
TeprotideIC50220.0 [1]
FosinoprilIC501.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Angiotensin-converting enzyme Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/angiotensin-converting-enzyme-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 8). Quest Database™ Angiotensin-converting enzyme Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/angiotensin-converting-enzyme-inhibitors-ic50-ki.
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