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Anti-estrogen binding site (AEBS) Inhibitors (IC50, Ki)
| Structure ▲ ▼ | Compound Name ▲ ▼ | Standard Type ▲ ▼ | Standard Values (in nM) ▲ ▼ |
 | Doxorubicin | IC50 | 150.0 [1], 200.0 [2], 300.0 [3] |
 | 2-Hydroxy-N-[[[(2S,3S,4S,6R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]methyl]benzamide | IC50 | 50.0 [1], 70.0 [2], 80.0 [3] |
 | 2-Hydroxy-N-[[[(2S,3S,4S,6R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]methyl]-5-[(E)-2-[2-[2-[2-[4-[(E)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenoxy]ethyl-methylamino]ethoxy]ethoxy]ethoxyiminomethyl]benzamide | IC50 | 30.0 [1], 40.0 [2] |
 | Tamoxifen | IC50 | 12.0 [1] |
 | Epipachysamine D | IC50 | 20000.0 [1] |
 | Axillaridine A | IC50 | 8000.0 [1] |
 | Pachyaximine A | IC50 | 400.0 [1] |
 | 4-(2-Chloro-1-(4-(2-(diethylamino)ethoxy)phenyl)-2-phenylethenyl)-2-methoxyphenol | IC50 | 22.0 [1] |
 | 4-(1-Chloro-2-(4-(2-(diethylamino)ethoxy)phenyl)-2-phenylethenyl)-2-methoxyphenol | IC50 | 32.0 [1] |
 | Pachysamine B | IC50 | 600.0 [1] |
References
This online tool may be cited as follows
MLA | "Quest Database™ Anti-estrogen binding site (AEBS) Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/anti-estrogen-binding-site-aebs-inhibitors-ic50-ki. | |
APA | AAT Bioquest, Inc. (2024, May 9). Quest Database™ Anti-estrogen binding site (AEBS) Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/anti-estrogen-binding-site-aebs-inhibitors-ic50-ki. | |
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