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Arachidonate 12-lipoxygenase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Nordihydroguaiaretic acidIC502600.0 [1]
CID 70701426IC50340.0 [1]
CID 70701426Ki350.0 [1], 720.0 [2]
N-(1,3-Benzoxazol-2-yl)-4-[(2-hydroxy-3-methoxyphenyl)methylamino]benzenesulfonamideIC50790.0 [1]
N-(1,3-Benzoxazol-2-yl)-4-[(2-hydroxy-3-methoxyphenyl)methylamino]benzenesulfonamideKi530.0 [1], 620.0 [2]
BaicaleinIC50860.0 [1]
BaicaleinKi1600.0 [1]
PhenidoneIC50100.0 [1]
PuupehenoneIC502400.0 [1], 22000.0 [2]
N-[(8-Hydroxy-5-nitro-quinolin-7-yl)-thiophen-2-yl-methyl]-propionamideIC50800.0 [1], 15000.0 [2]
N-[(5-Bromo-8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]acetamideIC5013000.0 [1], 25000.0 [2]
Tribromobisphenol AIC505000.0 [1], 7000.0 [2]
Phenol, 2,3,4,5-tetrabromo-6-(2,4-dibromophenoxy)-IC50700.0 [1], 1800.0 [2]
Jaspic acidIC507600.0 [1], 7900.0 [2]
4-Ethyl-6-(4-phenoxy-1H-pyrazol-3-yl)-1,3-BenzenediolIC5012300.0 [1]
Isojaspic acidIC503100.0 [1], 31000.0 [2]
QuercetinIC50440.0 [1]
2-BromophenolIC50100000.0 [1]
3-HydroxyflavoneIC50100000.0 [1]
FisetinIC50950.0 [1]
ZileutonIC5055000.0 [1]
Tetrabromobisphenol AIC5010000.0 [1]
4-BromophenolIC50100000.0 [1]
alpha-MangostinIC50580.0 [1]
HexylresorcinolIC5010000.0 [1]
7-HydroxyflavoneIC50100000.0 [1]
2,4-DibromophenolIC50100000.0 [1]
MorusinIC50100000.0 [1]
6-HydroxyflavoneIC50100000.0 [1]
2,6-DibromophenolIC50100000.0 [1]
ChloroxineIC501900.0 [1]
6,7,4'-TrihydroxyisoflavoneIC508700.0 [1]
3,7-DihydroxyflavoneIC50100000.0 [1]
3,6-DihydroxyflavoneIC50100000.0 [1]
13-Keto-9Z,11E-octadecadienoic acidIC50100000.0 [1]
HydrazinocurcuminIC507300.0 [1]
3-BromophenolIC50100000.0 [1]
5-Oxo-ETEIC5015000.0 [1]
Moracin CIC50210.0 [1]
N-[(5-Chloro-8-hydroxyquinolin-7-yl)-(furan-2-yl)methyl]propanamideIC501000.0 [1]
15-Oxo-ETEIC501000.0 [1]
3,5-DihydroxyflavoneIC50100000.0 [1]
12-Oxo-ETEIC508000.0 [1]
Phenol, 2,3,5-tribromo-6-(3,5-dibromo-2-hydroxyphenoxy)-IC506200.0 [1]
2,3,4,5-Tetrabromo-6-(3,5-dibromo-2-hydroxyphenoxy)phenolIC50410.0 [1]
4-{[5-(1-Naphthyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-2-butynyl 2-thiophenecarboxylateIC50100000.0 [1]
DysideninKi9000.0 [1]
Spongiadioxin AIC5050000.0 [1]
JaspaquinolIC5050000.0 [1]
(12E,25E,28E)-5,16,21,32-Tetrabromo-4,20-dihydroxy-12,25-bis(hydroxyimino)-2,18-dioxa-10,27-diazapentacyclo[28.2.2.214,17.13,7.119,23]octatriaconta-1(32),3,5,7(38),14,16,19,21,23(35),28,30,33,36-tridecaene-11,26-dioneIC502300.0 [1]
N-(3-(2-Methoxybenzamido)phenyl)thiophene-2-carboxamideIC50100000.0 [1]
Sodium;[(1S)-8-hydroxy-1-methyl-12,17-dioxo-14-oxapentacyclo[11.6.1.02,11.04,9.016,20]icosa-2,4,6,8,10,13(20),15-heptaen-5-yl] sulfateIC50200000.0 [1]
N-[(5-Chloro-8-hydroxyquinolin-7-yl)-(4-methylphenyl)methyl]propanamideIC50150000.0 [1]
N-[(5-Chloro-8-hydroxyquinolin-7-yl)-thiophen-2-ylmethyl]propanamideIC5025000.0 [1]
TexasinIC50100000.0 [1]
4-[(2-Hydroxy-3-methoxybenzyl)amino]-N-1,3-thiazol-2-ylbenzenesulfonamideIC505100.0 [1]
Pyridine-2,6-dicarboxylic acid bis-(phenethyl-amide)IC50200000.0 [1]
N-(3-(2-Methylbenzamido)phenyl)thiophene-2-carboxamideIC50100000.0 [1]
N-Benzyl-3-((2,3-dihydro-1H-inden-5-yloxy)methyl)benzamideIC50500000.0 [1]
N-[(5-Chloro-8-hydroxy-7-quinolinyl)-(2-furanyl)methyl]acetamideIC503000.0 [1]
N-[(8-Hydroxyquinolin-7-yl)-thiophen-2-ylmethyl]propanamideIC503400.0 [1]
CID 44142338IC5075000.0 [1]
N-[(5-Chloro-8-methoxyquinolin-7-yl)-(furan-2-yl)methyl]propanamideIC5075000.0 [1]
N-[1-(5-Chloro-8-hydroxyquinolin-7-yl)ethyl]propanamideIC5050000.0 [1]
N-[1-(5-Chloro-8-hydroxyquinolin-7-yl)-2-methylpropyl]propanamideIC501200.0 [1]
N-[(5-Chloro-8-hydroxyquinolin-7-yl)-cyclopropylmethyl]propanamideIC501600.0 [1]
N-[1-(5-Chloro-8-hydroxyquinolin-7-yl)ethyl]acetamideIC50150000.0 [1]
N-[1-(5-Chloro-8-hydroxyquinolin-7-yl)-2-methylpropyl]acetamideIC502600.0 [1]
N-[(5-Chloro-8-hydroxy-7-quinolinyl)-cyclopropylmethyl]acetamideIC503000.0 [1]
N-[(2,5-Dichloro-8-hydroxyquinolin-7-yl)-(furan-2-yl)methyl]acetamideIC5075000.0 [1]
N-[1-(5-Fluoro-8-hydroxyquinolin-7-yl)ethyl]acetamideIC5075000.0 [1]
N-[(5-Fluoro-8-hydroxyquinolin-7-yl)-(furan-2-yl)methyl]acetamideIC505000.0 [1]
N-[(5-Fluoro-8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]acetamideIC502000.0 [1]
4-(5-(Naphthalen-1-yl)-1,3,4-oxadiazol-2-ylthio)but-2-ynyl benzo[b]thiophene-2-carboxylateIC50100000.0 [1]
N-[(5-Bromo-8-hydroxy-7-quinolinyl)-(2-furanyl)methyl]propanamideIC502000.0 [1]
4-Bromobenzyl alcoholIC50100000.0 [1]
Ethyl 1-(3-(3,5-dimethylphenylamino)-3-oxopropyl)piperidine-4-carboxylateIC50100000.0 [1]
4-Methyl-2-[5-(2-methylphenyl)-1H-pyrazol-3-yl]phenolIC5050000.0 [1]
ChloropuupehenoneIC502400.0 [1]
2,4-Dibromo-6-(2,4-dibromo-6-methoxyphenoxy)phenolIC5012000.0 [1]
[1,1'-Biphenyl]-2,4-diolIC5010000.0 [1]
3-((N-(Aminocarbonyl)-N-hydroxyamino)methyl)-6-phenoxychromeneIC50640.0 [1]
N-[(5-Chloro-8-hydroxyquinolin-7-yl)-thiophen-2-ylmethyl]acetamideIC501000.0 [1]
4-[2-(3-Carboxy-4-hydroxynaphthalen-1-yl)-2-oxoacetyl]-1-hydroxynaphthalene-2-carboxylic acidIC50150.0 [1]
Spongiadioxin CIC5030000.0 [1]
N-[2-[2-(1-Benzofuran-2-yl)-1H-indol-3-yl]ethyl]-4-pentylbenzenesulfonamideIC503000.0 [1]
6,7,4'-TrihydroxyisoflavanoneIC503800.0 [1]
6,7,4'-TrihydroxyisoflavanIC5017000.0 [1]
NeodysideninIC50100000.0 [1]
6-Phenyl-[1,3]dioxolo[4,5-g]chromen-8-oneIC50100000.0 [1]
Dimethylnordihydroguarierate acidIC503100.0 [1]
4-[(2S,3R)-4-(3,4-Dimethoxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diolIC5042000.0 [1]
(4As,6aS,12bS)-10-methoxy-4,4,6a,12b-tetramethyl-1,2,3,4a,5,6-hexahydrobenzo[a]xanthen-9-olIC50780.0 [1]
4H-1-Benzopyran-4-one, 2-(1,1-dimethylethyl)-6-hydroxy-IC50100000.0 [1]
3,4,6-Tribromo-2-(2,4-dibromophenoxy)phenolIC506000.0 [1]
(+)-(5S,8S,10S)-20-MethoxypuupehenolIC50280.0 [1]
2-([1,2,4]Triazolo[4,3-a]quinolin-1-ylthio)-N-phenethylacetamideIC50100000.0 [1]
4-[(E)-2-[3-(4-Hydroxy-3-methoxyphenyl)-1H-pyrazol-5-yl]ethenyl]-2-methoxyphenolIC507700.0 [1]
2,3-Dihydro-6,7-dihydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-oneIC501600.0 [1]
1-{[6-(4-Fluorophenoxy)-2h-chromen-3-yl]methyl}-1-hydroxy-3-methylureaIC50410.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Arachidonate 12-lipoxygenase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/arachidonate-12-lipoxygenase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 8). Quest Database™ Arachidonate 12-lipoxygenase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/arachidonate-12-lipoxygenase-inhibitors-ic50-ki.
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