 | 3,5-Dichlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate | IC50 | 2.8 [1] |
 | Ziritaxestat | IC50 | 100.0 [1] |
| Ziritaxestat | Ki | 15.0 [1] |
 | 2-[4-[(3,5-Dichlorophenyl)carbamothioyl]piperazin-1-yl]-8-ethyl-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid | IC50 | 1200.0 [1], 1600.0 [2] |
| 2-[4-[(3,5-Dichlorophenyl)carbamothioyl]piperazin-1-yl]-8-ethyl-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid | Ki | 1900.0 [1], 6500.0 [2] |
 | 8-Ethyl-5-oxo-2-[4-(9H-xanthene-9-carbonylcarbamothioyl)piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid | IC50 | 1500.0 [1], 1700.0 [2] |
| 8-Ethyl-5-oxo-2-[4-(9H-xanthene-9-carbonylcarbamothioyl)piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid | Ki | 2700.0 [1], 19800.0 [2] |
 | ATX inhibitor 1 | IC50 | 1.23 [1], 1.3 [2], 2.18 [3], 7.9 [4], 136.0 [5] |
 | Sodium | IC50 | 922.0 [1], 1310.0 [2] |
| Sodium | Ki | 824.0 [1], 1890.0 [2] |
 | 4-(4-(2-(Naphthalen-1-yl)-1,3-dioxoisoindoline-5-carbonyl)phenoxy)benzoic acid | IC50 | 6800.0 [1] |
| 4-(4-(2-(Naphthalen-1-yl)-1,3-dioxoisoindoline-5-carbonyl)phenoxy)benzoic acid | Ki | 5800.0 [1], 32300.0 [2] |
 | 6-[6-Chloro-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylpyridine-2-carboxylic acid | IC50 | 4.0 [1], 22.0 [2], 300.0 [3] |
 | 3,5-Dichlorobenzyl 4-(4-(1H-1,2,3-triazol-4-yl)butanamido)piperidine-1-carboxylate | IC50 | 2.0 [1], 3.1 [2], 9.0 [3] |
 | 1-Oleoyl-sn-glycerol 3-phosphate | IC50 | 442.0 [1], 499.8 [2] |
| 1-Oleoyl-sn-glycerol 3-phosphate | Ki | 100.0 [1] |
 | Anti-BrP-LPA | IC50 | 22.0 [1] |
 | 2,4-Dichloro-N-(3-fluorophenyl)-5-(morpholin-4-ylsulfonyl)benzamide | IC50 | 31.4 [1], 116.0 [2], 117.0 [3] |
 | [4-[2-[[1-[(3,5-Dichlorophenyl)methoxycarbonyl]piperidin-4-yl]carbamoyl]-1,3-thiazol-4-yl]phenyl]methylphosphonic acid | IC50 | 2.19 [1], 14.99 [2] |
 | 3-(3-Benzylimidazo[4,5-b]pyridin-2-yl)-N-[(4-methoxyphenyl)methyl]propanamide | IC50 | 40.0 [1], 473.0 [2], 8870.0 [3] |
 | [(2R,3S)-3-(Hexadecanoylamino)-2-hydroxy-4-[4-[(4-methoxy-3,5-dimethylpyridin-2-yl)methoxy]phenyl]butyl]phosphonic acid | Ki | 390.0 [1], 1000.0 [2], 1300.0 [3] |
 | 3-(1,3-Dioxo-2-(4-(phenyldiazenyl)phenyl)isoindoline-5-carboxamido)benzoic acid | IC50 | 12800.0 [1] |
| 3-(1,3-Dioxo-2-(4-(phenyldiazenyl)phenyl)isoindoline-5-carboxamido)benzoic acid | Ki | 15100.0 [1], 40300.0 [2] |
 | 2-[[2-Ethyl-6-[1-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperidin-4-yl]imidazo[1,2-a]pyridin-3-yl]-methylamino]-4-(4-fluorophenyl)-1,3-thiazole-5-carbonitrile | IC50 | 27.0 [1] |
 | N-[(1S)-1-(4-Chlorophenyl)ethyl]-3-[3-[[4-(trifluoromethoxy)phenyl]methyl]imidazo[4,5-b]pyridin-2-yl]propanamide | IC50 | 1.0 [1], 14.0 [2], 38.0 [3] |
 | (4-Tetradecylphenyl)methylphosphonic acid | IC50 | 170.0 [1] |
| (4-Tetradecylphenyl)methylphosphonic acid | Ki | 270.0 [1], 280.0 [2] |
 | 8-Ethyl-5-oxo-2-[4-[[4-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid | IC50 | 1500.0 [1] |
| 8-Ethyl-5-oxo-2-[4-[[4-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid | Ki | 13200.0 [1] |
 | 8-Ethyl-2-[4-[(3-iodophenyl)carbamothioyl]piperazin-1-yl]-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid | IC50 | 1600.0 [1] |
| 8-Ethyl-2-[4-[(3-iodophenyl)carbamothioyl]piperazin-1-yl]-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid | Ki | 7400.0 [1], 11000.0 [2] |
 | 2-[4-[(3-Chlorophenyl)carbamothioyl]piperazin-1-yl]-8-ethyl-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid | IC50 | 2500.0 [1] |
| 2-[4-[(3-Chlorophenyl)carbamothioyl]piperazin-1-yl]-8-ethyl-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid | Ki | 2600.0 [1], 47300.0 [2] |
 | 2-[4-[(2,5-Dichlorophenyl)carbamothioyl]piperazin-1-yl]-8-ethyl-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid | IC50 | 1300.0 [1] |
| 2-[4-[(2,5-Dichlorophenyl)carbamothioyl]piperazin-1-yl]-8-ethyl-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid | Ki | 3400.0 [1], 22000.0 [2] |
 | 8-Ethyl-2-[4-[(4-iodophenyl)carbamothioyl]piperazin-1-yl]-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid | IC50 | 5600.0 [1] |
| 8-Ethyl-2-[4-[(4-iodophenyl)carbamothioyl]piperazin-1-yl]-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid | Ki | 13200.0 [1], 34100.0 [2] |
 | 4-[[2-[(3-Ethyl-4-oxo-6,7,8,9-tetrahydropyrimido[4,5-b]quinolin-2-yl)sulfanyl]acetyl]amino]benzoic acid | IC50 | 1600.0 [1] |
| 4-[[2-[(3-Ethyl-4-oxo-6,7,8,9-tetrahydropyrimido[4,5-b]quinolin-2-yl)sulfanyl]acetyl]amino]benzoic acid | Ki | 6500.0 [1], 9300.0 [2] |
 | 3-(6-Chloranyl-2-Methyl-1-Phenyl-Indol-3-Yl)sulfanylbenzoic Acid | IC50 | 5.0 [1], 81.0 [2], 300.0 [3] |
 | 3-(6-Chloro-1,2-dimethyl-1H-indol-3-ylsulfanyl)-benzoic acid | IC50 | 100.0 [1], 1000.0 [2], 1200.0 [3] |
 | [3,5-Bis(trifluoromethyl)phenyl]methyl (1R,5S)-6-[(2H-benzotriazole-5-carbonylamino)methyl]-3-azabicyclo[3.1.0]hexane-3-carboxylate | IC50 | 2.2 [1], 29.0 [2] |
 | 4-[[5-[2-[(4-Carboxyphenyl)methyl]-1,3-dioxoisoindole-5-carbonyl]-1,3-dioxoisoindol-2-yl]methyl]benzoic acid | IC50 | 12800.0 [1] |
| 4-[[5-[2-[(4-Carboxyphenyl)methyl]-1,3-dioxoisoindole-5-carbonyl]-1,3-dioxoisoindol-2-yl]methyl]benzoic acid | Ki | 5000.0 [1] |
 | N-(4-Bromophenyl)-2-[[5-cyano-4-(4-hydroxy-3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyridin-6-yl]sulfanyl]acetamide | IC50 | 3800.0 [1] |
| N-(4-Bromophenyl)-2-[[5-cyano-4-(4-hydroxy-3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyridin-6-yl]sulfanyl]acetamide | Ki | 9800.0 [1] |
 | [4-[[4-[(Z)-[3-[(4-Fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]phenoxy]methyl]phenyl]boronic acid | IC50 | 5.67 [1], 5.7 [2] |
 | [(3S)-1-Bromo-3-hydroxy-4-octadecanoyloxybutyl]phosphonic acid | IC50 | 170.3 [1] |
| [(3S)-1-Bromo-3-hydroxy-4-octadecanoyloxybutyl]phosphonic acid | Ki | 40100.0 [1] |
 | 2-[4-[2-Ethyl-3-[[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-methylamino]imidazo[1,2-a]pyridin-6-yl]piperidin-1-yl]-1-(3-hydroxyazetidin-1-yl)ethanone | IC50 | 246.0 [1] |
 | N-(2-Ethyl-6-morpholin-4-ylimidazo[1,2-a]pyridin-3-yl)-4-(4-fluorophenyl)-N-methyl-1,3-thiazol-2-amine | IC50 | 8.0 [1], 6800.0 [2] |
 | 3-[(6-Chloro-2-methyl-1H-indol-3-yl)sulfanyl]benzoic acid | IC50 | 290.0 [1], 747.0 [2] |
 | N-[(1S)-1-(4-Chlorophenyl)ethyl]-2-[3-[[4-(trifluoromethoxy)phenyl]methyl]imidazo[4,5-b]pyridin-2-yl]oxyacetamide | IC50 | 5.0 [1], 99.0 [2] |
 | 3-(3-Benzylimidazo[4,5-b]pyridin-2-yl)-N-(cyclohexylmethyl)propanamide | IC50 | 444.0 [1], 9700.0 [2] |
 | [3-[(4-Fluorophenyl)methyl]imidazo[4,5-b]pyridin-2-yl]methyl N-[(1S)-1-(4-fluorophenyl)ethyl]carbamate | IC50 | 366.0 [1], 3294.0 [2] |
 | N-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[3-[(4-fluorophenyl)methyl]imidazo[4,5-b]pyridin-2-yl]propanamide | IC50 | 6.0 [1], 444.0 [2] |
 | 3-(3-Benzylimidazo[4,5-b]pyridin-2-yl)-N-[(1S)-1-phenylethyl]propanamide | IC50 | 68.0 [1], 288.0 [2] |
 | N-[(1S)-1-(4-Fluorophenyl)ethyl]-2-[3-[[4-(trifluoromethoxy)phenyl]methyl]imidazo[4,5-b]pyridin-2-yl]sulfanylacetamide | IC50 | 2.0 [1], 19.0 [2] |
 | N-[(1S)-1-(4-Chlorophenyl)ethyl]-3-[3-[[4-(trifluoromethyl)phenyl]methyl]imidazo[4,5-b]pyridin-2-yl]propanamide | IC50 | 2.0 [1], 16.0 [2] |
 | N-[(1S)-1-(4-Chlorophenyl)ethyl]-3-[3-[[4-(trifluoromethoxy)phenyl]methyl]imidazo[4,5-c]pyridin-2-yl]propanamide | IC50 | 3.0 [1], 34.0 [2] |
 | N-[(1S)-1-(4-Chlorophenyl)ethyl]-3-[3-[[4-(difluoromethoxy)phenyl]methyl]imidazo[4,5-b]pyridin-2-yl]propanamide | IC50 | 2.0 [1], 44.0 [2] |
 | N-[(1S)-1-(4-Chlorophenyl)ethyl]-3-[3-[(4-methoxyphenyl)methyl]imidazo[4,5-b]pyridin-2-yl]propanamide | IC50 | 3.0 [1], 215.0 [2] |
 | N-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[3-[[4-(trifluoromethoxy)phenyl]methyl]imidazo[4,5-c]pyridin-2-yl]propanamide | IC50 | 8.0 [1], 32.0 [2] |
 | N-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[3-[(4-fluorophenyl)methyl]imidazo[4,5-c]pyridin-2-yl]propanamide | IC50 | 52.0 [1], 333.0 [2] |
 | 1-[(1S)-1-(4-Chlorophenyl)ethyl]-3-[[3-[(4-fluorophenyl)methyl]imidazo[4,5-b]pyridin-2-yl]methyl]urea | IC50 | 10.0 [1], 414.0 [2] |
 | N-[(1S)-1-(4-Fluorophenyl)ethyl]-2-[3-[(4-fluorophenyl)methyl]imidazo[4,5-b]pyridin-2-yl]oxyacetamide | IC50 | 39.0 [1], 821.0 [2] |
 | 3-[3-[(4-Methoxyphenyl)methyl]imidazo[4,5-b]pyridin-2-yl]-N-[(1R)-1-phenylethyl]propanamide | IC50 | 1060.0 [1], 8500.0 [2] |
 | N-[(1S)-1-(4-Fluorophenyl)ethyl]-2-[3-[[4-(trifluoromethoxy)phenyl]methyl]imidazo[4,5-b]pyridin-2-yl]sulfinylacetamide | IC50 | 178.0 [1], 207.0 [2] |
 | 3-[3-[(4-Methoxyphenyl)methyl]imidazo[4,5-b]pyridin-2-yl]-N-[(1S)-1-phenylethyl]propanamide | IC50 | 17.0 [1], 318.0 [2] |
 | 1-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[[3-[(4-fluorophenyl)methyl]imidazo[4,5-b]pyridin-2-yl]methyl]urea | IC50 | 80.0 [1], 1050.0 [2] |
 | 4-[[4-[(Z)-[3-[(4-Fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]-2-methoxyphenoxy]methyl]benzoic acid | IC50 | 56.0 [1], 2500.0 [2] |
 | (3,5-Dichlorophenyl)methyl (3R)-3-[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]pyrrolidine-1-carboxylate | IC50 | 20.0 [1] |
| (3,5-Dichlorophenyl)methyl (3R)-3-[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]pyrrolidine-1-carboxylate | Ki | 6.0 [1] |
 | N-[(1R)-1-(4-Chlorophenyl)-2-hydroxyethyl]-3-[3-[(4-fluorophenyl)methyl]imidazo[4,5-b]pyridin-2-yl]propanamide | IC50 | 5.0 [1], 26.0 [2] |
 | 5-Amino-3-[[4-[4-[(6-amino-3-hydroxy-1-sulfonaphthalen-2-yl)diazenyl]phenyl]phenyl]diazenyl]-4-hydroxynaphthalene-2,7-disulfonic acid | IC50 | 1260.0 [1] |
| 5-Amino-3-[[4-[4-[(6-amino-3-hydroxy-1-sulfonaphthalen-2-yl)diazenyl]phenyl]phenyl]diazenyl]-4-hydroxynaphthalene-2,7-disulfonic acid | Ki | 1460.0 [1] |
 | (3,5-Dichlorophenyl)methyl 4-[[4-[4-(methanesulfonamido)phenyl]-1,3-thiazole-2-carbonyl]amino]piperidine-1-carboxylate | IC50 | 2.99 [1], 735.0 [2] |
 | 6-[6-Methoxy-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylpyridine-2-carboxylic acid | IC50 | 75.0 [1], 124.0 [2] |
 | 6-(6-Chloro-1-cyclopentyl-2-methylindol-3-yl)sulfanylpyridine-2-carboxylic acid | IC50 | 2000.0 [1], 2800.0 [2] |
 | 3-(2-Methyl-1-phenylindol-3-yl)sulfanylbenzoic acid | IC50 | 5000.0 [1], 30000.0 [2] |
 | Ethyl 4-[[3-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-methylamino]-2-ethylimidazo[1,2-a]pyridin-6-yl]methylamino]piperidine-1-carboxylate | IC50 | 9.0 [1], 1210.0 [2] |
 | 6-[(6-Chloro-2-methyl-1H-indol-3-yl)sulfanyl]pyridine-2-carboxylic acid | IC50 | 25.0 [1], 604.0 [2] |
 | Ethyl 4-[[3-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-methylamino]-2-ethylimidazo[1,2-a]pyridine-6-carbonyl]amino]piperidine-1-carboxylate | IC50 | 5.0 [1], 6555.0 [2] |
 | 6-(6-Chloro-1,2-dimethylindol-3-yl)sulfanylpyridine-2-carboxylic acid | IC50 | 31.0 [1], 4000.0 [2] |
 | 6-[2,6-Dimethyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylpyridine-2-carboxylic acid | IC50 | 25.0 [1], 85.0 [2] |
 | 3-[6-Chloro-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]oxybenzoic acid | IC50 | 204.0 [1], 726.0 [2] |
 | 3-[[6-Chloro-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]methyl]benzoic acid | IC50 | 33.0 [1], 660.0 [2] |
 | 6-[6-Fluoro-2-methyl-1-(1-methylpyrazol-3-yl)indol-3-yl]sulfanylpyridine-2-carboxylic acid | IC50 | 349.0 [1], 816.0 [2] |
 | 6-[[6-Chloro-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]methyl]pyridine-2-carboxylic acid | IC50 | 89.0 [1], 339.0 [2] |
 | 6-[2-Methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylpyridine-2-carboxylic acid | IC50 | 1700.0 [1], 5700.0 [2] |
 | N-(2-Ethyl-6-pyridin-3-ylimidazo[1,2-a]pyridin-3-yl)-4-(4-fluorophenyl)-N-methyl-1,3-thiazol-2-amine | IC50 | 2.0 [1], 10000.0 [2] |
 | 3-(6-Chloro-1-cyclopentyl-2-methylindol-3-yl)sulfanylbenzoic acid | IC50 | 4000.0 [1], 20000.0 [2] |
 | [4-[(1-Phenylmethoxycarbonylpiperidine-4-carbonyl)amino]phenyl]methylphosphonic acid | IC50 | 7.17 [1], 255.0 [2] |
 | [2-[[1-[(3,5-Dichlorophenyl)methoxycarbonyl]piperidine-4-carbonyl]amino]-1,3-thiazol-4-yl]methylphosphonic acid | IC50 | 1.75 [1], 26.5 [2] |
 | [4-[[1-[(3-Chlorophenyl)methoxycarbonyl]piperidine-4-carbonyl]amino]phenyl]methylphosphonic acid | IC50 | 1.79 [1], 39.6 [2] |
 | [4-[[1-[[4-(Trifluoromethoxy)phenyl]methoxycarbonyl]piperidine-4-carbonyl]amino]phenyl]methylphosphonic acid | IC50 | 1.97 [1], 3.12 [2] |
 | (3,5-Dichlorophenyl)methyl 4-[[4-(hydroxycarbamoyl)phenyl]carbamoyl]piperidine-1-carboxylate | IC50 | 18.72 [1], 496.0 [2] |
 | [4-[[1-[[2-Fluoro-4-(trifluoromethoxy)phenyl]methoxycarbonyl]piperidine-4-carbonyl]amino]phenyl]methylphosphonic acid | IC50 | 1.67 [1], 2.78 [2] |
 | [2-[[1-[(3,5-Dichlorophenyl)methoxycarbonyl]pyrrolidin-3-yl]carbamoyl]-1,3-thiazol-4-yl]methylphosphonic acid | IC50 | 3.71 [1], 54.7 [2] |
 | [4-[[1-[(2-Chlorophenyl)methoxycarbonyl]piperidine-4-carbonyl]amino]phenyl]methylphosphonic acid | IC50 | 3.29 [1], 213.0 [2] |
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