Baculoviral IAP repeat-containing protein 7 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Gdc-0152	Ki	50.0 [1]
	(2S)-N-[(1S)-2-[(2S)-2-[4-(4-Fluoronaphthalen-1-yl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-1-(oxan-4-yl)-2-oxoethyl]-2-(methylamino)propanamide	Ki	40000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-(4-naphthalen-1-yl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamide	Ki	110000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-oxo-2-[(2S)-2-(4-phenyl-1,3-benzothiazol-2-yl)pyrrolidin-1-yl]ethyl]-2-(methylamino)propanamide	Ki	53000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-oxo-2-[(2S)-2-(7-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-2-yl)pyrrolidin-1-yl]ethyl]-2-(methylamino)propanamide	Ki	130000.0 [1]
	(2S)-N-[(1S)-2-[(2S)-2-(5-Ethynyl-4-naphthalen-1-yl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-1-(oxan-4-yl)-2-oxoethyl]-2-(methylamino)propanamide	Ki	160000.0 [1]
	(2S)-2-(Methylamino)-N-[(1S)-2-[(2S)-2-(4-naphthalen-1-yl-5-prop-1-ynyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-1-(oxan-4-yl)-2-oxoethyl]propanamide	Ki	160000.0 [1]
	(2S)-N-[(1S)-2-[(2S)-2-[5-(3-Methoxyprop-1-ynyl)-4-naphthalen-1-yl-1,3-thiazol-2-yl]pyrrolidin-1-yl]-1-(oxan-4-yl)-2-oxoethyl]-2-(methylamino)propanamide	Ki	140000.0 [1]
	(2S)-N-[(1S)-2-[(2S)-2-[5-(3-Hydroxyprop-1-ynyl)-4-naphthalen-1-yl-1,3-thiazol-2-yl]pyrrolidin-1-yl]-1-(oxan-4-yl)-2-oxoethyl]-2-(methylamino)propanamide	Ki	140000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-(4-methyl-1,3-benzothiazol-2-yl)pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamide	Ki	2700000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-oxo-2-[(2S)-2-(4-propan-2-yl-1,3-benzothiazol-2-yl)pyrrolidin-1-yl]ethyl]-2-(methylamino)propanamide	Ki	2800000.0 [1]
	(2S)-N-[(1S)-2-[(2S)-2-(4-Benzyl-1,3-benzothiazol-2-yl)pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]-2-(methylamino)propanamide	Ki	710000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-oxo-2-[(2S)-2-(4-pyridin-3-yl-1,3-benzothiazol-2-yl)pyrrolidin-1-yl]ethyl]-2-(methylamino)propanamide	Ki	200000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-oxo-2-[(2S)-2-(4-pyridin-4-yl-1,3-benzothiazol-2-yl)pyrrolidin-1-yl]ethyl]-2-(methylamino)propanamide	Ki	460000.0 [1]
	(2S)-N-[(1S)-2-[(2S)-2-[4-(2-Chlorophenyl)-1,3-benzothiazol-2-yl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]-2-(methylamino)propanamide	Ki	730000.0 [1]
	(2S)-N-[(1S)-2-[(2S)-2-[4-(3-Chlorophenyl)-1,3-benzothiazol-2-yl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]-2-(methylamino)propanamide	Ki	140000.0 [1]
	(2S)-N-[(1S)-2-[(2S)-2-[4-(4-Chlorophenyl)-1,3-benzothiazol-2-yl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]-2-(methylamino)propanamide	Ki	68000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(2-fluorophenyl)-1,3-benzothiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamide	Ki	130000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(3-fluorophenyl)-1,3-benzothiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamide	Ki	130000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(4-fluorophenyl)-1,3-benzothiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamide	Ki	44000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-oxo-2-[(2S)-2-(7-phenyl-[1,3]thiazolo[5,4-b]pyridin-2-yl)pyrrolidin-1-yl]ethyl]-2-(methylamino)propanamide	Ki	36000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-oxo-2-[(2S)-2-(7-phenyl-[1,3]thiazolo[5,4-c]pyridin-2-yl)pyrrolidin-1-yl]ethyl]-2-(methylamino)propanamide	Ki	49000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-(5-methyl-7-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-2-yl)pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamide	Ki	32000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-oxo-2-[(2S)-2-(4-phenyl-[1,3]thiazolo[4,5-c]pyridin-2-yl)pyrrolidin-1-yl]ethyl]-2-(methylamino)propanamide	Ki	24000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-oxo-2-[(2S)-2-(4-phenyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]ethyl]-2-(methylamino)propanamide	Ki	1200000.0 [1]
	(2S)-N-[(2S)-3,3-Dimethyl-1-[(2S)-2-(4-naphthalen-1-yl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-1-oxobutan-2-yl]-2-(methylamino)propanamide	Ki	220000.0 [1]
	(2S)-2-(Methylamino)-N-[(1S)-2-[(2S)-2-(4-naphthalen-1-yl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-1-(oxan-4-yl)-2-oxoethyl]propanamide	Ki	100000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(4-fluoronaphthalen-1-yl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamide	Ki	68000.0 [1]
	(2S)-N-[(1S)-1-Cyclohexyl-2-oxo-2-[(2S)-2-(4-quinolin-4-yl-1,3-thiazol-2-yl)pyrrolidin-1-yl]ethyl]-2-(methylamino)propanamide	Ki	45000.0 [1]
	(2S)-N-[(2S)-3,3-Dimethyl-1-oxo-1-[(2S)-2-(4-quinolin-4-yl-1,3-thiazol-2-yl)pyrrolidin-1-yl]butan-2-yl]-2-(methylamino)propanamide	Ki	180000.0 [1]
	(2S)-N-[(1S)-2-[(2S)-2-[4-(1-Benzofuran-3-yl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]-2-(methylamino)propanamide	Ki	200000.0 [1]
	(2S)-N-[(1S)-2-[(2S)-2-[4-(1,2-Benzoxazol-3-yl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]-2-(methylamino)propanamide	Ki	130000.0 [1]
	(2S)-N-[(2S)-1-[(2S)-2-[4-(1-Benzothiophen-3-yl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]-2-(methylamino)propanamide	Ki	120000.0 [1]
	(2S)-N-[(1S)-2-[(2S)-2-(5-Fluoro-4-naphthalen-1-yl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-1-(oxan-4-yl)-2-oxoethyl]-2-(methylamino)propanamide	Ki	68000.0 [1]
	(2S)-N-[(1S)-2-[(2S)-2-(5-Chloro-4-naphthalen-1-yl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]-2-(methylamino)propanamide	Ki	210000.0 [1]
	(2S)-N-[(1S)-2-[(2S)-2-(5-Cyano-4-naphthalen-1-yl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-1-(oxan-4-yl)-2-oxoethyl]-2-(methylamino)propanamide	Ki	69000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 36 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Baculoviral IAP repeat-containing protein 7 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/baculoviral-iap-repeat-containing-protein-7-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Baculoviral IAP repeat-containing protein 7 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/baculoviral-iap-repeat-containing-protein-7-inhibitors-ic50-ki.
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