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Beta-galactosidase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Ethyl 5-[(2S,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]-2-methyl-3-furoateIC5012000.0 [1]
Ethyl 5-[(2S,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]-2-methyl-3-furoateKi6400.0 [1], 6600.0 [2]
(1s,2s,3s,6r)-4-(Hydroxymethyl)-6-(Octylamino)cyclohex-4-Ene-1,2,3-TriolIC50125.0 [1]
(1s,2s,3s,6r)-4-(Hydroxymethyl)-6-(Octylamino)cyclohex-4-Ene-1,2,3-TriolKi300.0 [1], 510.0 [2]
(3R,4S,5R,6R)-5-(Hydroxymethyl)-6-pentylpiperidine-3,4-diolIC508.0 [1], 10.0 [2], 180.0 [3]
[(1S,2R,6S,8S)-10,10-Dimethyl-3,7,9,11-tetraoxa-4-azatricyclo[6.3.0.02,6]undec-4-en-5-yl]methanolIC50150000.0 [1], 1000000.0 [2]
[(1S,2R,6S,8S)-10,10-Dimethyl-3,7,9,11-tetraoxa-4-azatricyclo[6.3.0.02,6]undec-4-en-5-yl]methanolKi72000.0 [1]
5-[(2S,3S,4R)-3,4-Dihydroxypyrrolidin-2-yl]-N,N-diethyl-2-methyl-3-furamideIC5065000.0 [1], 1000000.0 [2]
5-[(2S,3S,4R)-3,4-Dihydroxypyrrolidin-2-yl]-N,N-diethyl-2-methyl-3-furamideKi13000.0 [1]
D-Galacto-IsofagomineIC50240.0 [1], 12000.0 [2]
Methyl 6-[[(2S)-2-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]-6-[(2R,3S,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanoyl]amino]hexanoateIC507800.0 [1]
Methyl 6-[[(2S)-2-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]-6-[(2R,3S,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanoyl]amino]hexanoateKi600.0 [1]
2-(2,2-Dihydroxy-ethyl)-pyrrolidine-3,4-diolIC50110000.0 [1]
2-(2,2-Dihydroxy-ethyl)-pyrrolidine-3,4-diolKi25000.0 [1]
N-[(3R,4R,5S)-5-(1,2-Dihydroxyethyl)-2-hydroxy-4-[[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]oxolan-3-yl]acetamideIC509400.0 [1]
N-[(3R,4R,5S)-5-(1,2-Dihydroxyethyl)-2-hydroxy-4-[[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]oxolan-3-yl]acetamideKi7500.0 [1]
SodiumIC50100000.0 [1]
MigalastatIC5090000.0 [1]
AfegostatIC5010000.0 [1]
3-Hydroxy-4-((2-hydroxynaphthyl)azo)naphthalene-1-sulphonic acidIC50600000.0 [1]
Jodphthalein sodiumIC50200000.0 [1]
Rose Bengal lactoneIC5080000.0 [1]
Piperidine-3,4,5-triolIC5040000.0 [1]
4-(4-Bromophenylazo)phenolIC5090000.0 [1]
(3R,4S)-Pyrrolidine-3,4-diolIC50720000.0 [1]
N'1,N'2-Bis(2-Hydroxybenzylidene)OxalohydrazideIC50180000.0 [1]
(E)-3-(4-Isopropylbenzylidene)indolin-2-oneIC5055000.0 [1]
4-[2-(2,4-Difluoroanilino)-4-thiazolyl]pyrocatecholIC50320000.0 [1]
1-Naphthalenesulfonic acid, 3-hydroxy-4-[(1-hydroxy-2-naphthalenyl)azo]-IC50600000.0 [1]
(1R,7S)-1,7,8,9,10,10-Hexachloro-4-(2,4-dinitroanilino)-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dioneIC50150000.0 [1]
(2R,3R,4S,5R,6R)-2-(Hydroxymethyl)-6-(4-phenyltriazol-1-yl)oxane-3,4,5-triolKi330000.0 [1]
D&C Red No. 30IC50300000.0 [1]
5-(Dimethylamino)-N-[6-[(2R,3S,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexyl]naphthalene-1-sulfonamideKi300.0 [1]
Methyl (2S)-2-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]-6-[(2R,3S,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanoateKi700.0 [1]
5-[(2S,3S,4R)-3,4-Dihydroxypyrrolidin-2-yl]-N-isopropyl-2-methyl-3-furamideIC50500000.0 [1]
(3R,4S,5R,6R)-5-(Hydroxymethyl)-6-methylpiperidine-3,4-diolIC50250.0 [1]
(1S,2S,3S,4R)-Cyclohex-5-ene-1,2,3,4-tetrolIC50600000.0 [1]
(1S,2S,3S,6R)-4-(Hydroxymethyl)-6-(octylamino)cyclohex-4-ene-1,2,3-triol;hydrochlorideIC501700.0 [1]
(3R,4S,5R,6R)-5-(Hydroxymethyl)-6-nonylpiperidine-3,4-diolIC500.4 [1]
(3R,4S,5R,6R)-6-(2-Hydroxyethyl)-5-(hydroxymethyl)piperidine-3,4-diolIC502420.0 [1]
N-[4-[(2R,3R,4S,5R)-4,5-Dihydroxy-3-(hydroxymethyl)piperidin-2-yl]butyl]-5-(dimethylamino)naphthalene-1-sulfonamideIC50210.0 [1]
5-(Dimethylamino)-N-[6-[[(1R,2S,3S,4S,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclopentyl]amino]hexyl]naphthalene-1-sulfonamideKi290.0 [1]
(1S,2S,3S,4R,5R)-4-(6-Aminohexylamino)-5-(hydroxymethyl)cyclopentane-1,2,3-triolKi9200.0 [1]
(3R,4S,5S,6S)-5-(Hydroxymethyl)-6-pentylpiperidine-3,4-diolIC50150000.0 [1]
(3R,4S,5R,6S)-5-(Hydroxymethyl)-6-pentylpiperidine-3,4-diolIC5013000.0 [1]
(3R,4S,5R,6R)-5-(Hydroxymethyl)-6-(2-phenylethyl)piperidine-3,4-diolIC5010.0 [1]
3,4-Dichloro-N-[5-(5-chloro-benzothiazol-2-ylsulfanyl)-[1,3,4]thiadiazol-2-yl]-benzamideIC5015000.0 [1]
N-[6-[[5-(Dimethylamino)naphthalen-1-yl]sulfonylamino]hexyl]-6-[(2R,3S,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamideKi700.0 [1]
5-Methylpiperidine-3,4-diolIC501000000.0 [1]
(1S,2S,3S,6R)-6-(Decylamino)cyclohex-4-ene-1,2,3-triolIC5043000.0 [1]
(1S,2S,3S,6R)-6-(3-Hydroxypropylamino)cyclohex-4-ene-1,2,3-triolIC501000000.0 [1]
(1S,2S,3S,6R)-6-(2-Methylpropylamino)cyclohex-4-ene-1,2,3-triolIC5041000.0 [1]
(1S,2S,3S,6R)-6-(2-Ethylbutylamino)cyclohex-4-ene-1,2,3-triolIC5015000.0 [1]
(1S,2S,3S,6R)-6-(Cyclohexylmethylamino)cyclohex-4-ene-1,2,3-triolIC5060000.0 [1]
(1S,2S,3S,6R)-6-(Cyclohexylamino)cyclohex-4-ene-1,2,3-triolIC50490000.0 [1]
(1S,2S,3S,6R)-6-(3-Methylbutylamino)cyclohex-4-ene-1,2,3-triolIC5028000.0 [1]
(1S,2S,3S,6R)-6-(2-Phenylethylamino)cyclohex-4-ene-1,2,3-triolIC5086000.0 [1]
(1S,2S,3S,6R)-6-(Butylamino)cyclohex-4-ene-1,2,3-triolIC5050000.0 [1]
(1S,2S,3S,6R)-6-(Pentylamino)cyclohex-4-ene-1,2,3-triolIC5019000.0 [1]
(1S,2S,3S,6R)-6-(Pentan-3-ylamino)cyclohex-4-ene-1,2,3-triolIC501000000.0 [1]
(1S,2S,3S,6R)-6-(Hexylamino)cyclohex-4-ene-1,2,3-triolIC5056000.0 [1]
(1S,2S,3S,6R)-6-(Benzylamino)cyclohex-4-ene-1,2,3-triol;hydrochlorideIC50180000.0 [1]
(1S,2S,3S,6R)-6-(Octylamino)cyclohex-4-ene-1,2,3-triol;hydrochlorideIC50120000.0 [1]
5-Methylene-piperidine-3,4-diolIC501000000.0 [1]
1-Butyl-5-methyl-piperidine-3,4-diolIC501000000.0 [1]
5-Methoxy-piperidine-3,4-diolIC501000000.0 [1]
1-Butyl-piperidine-3,4,5-triolIC5043000.0 [1]
(1S,2S,3S,6R)-4-Methyl-6-(octylamino)cyclohex-4-ene-1,2,3-triolIC5046000.0 [1]
Items per page: 1 - 10 of 68
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References

This online tool may be cited as follows

MLA

"Quest Database™ Beta-galactosidase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/beta-galactosidase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Beta-galactosidase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/beta-galactosidase-inhibitors-ic50-ki.
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