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Brain glycogen phosphorylase Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
D-GlucoseKi1700000.0 [1], 7400000.0 [2], 125893000000.0 [3]
N-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]acetamideKi32000.0 [1], 31622800000000.0 [2]
N-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]benzamideKi81000.0 [1], 12589300000000.0 [2]
(5S,8S,9S)-8,9,10-Trihydroxy-7-(hydroxymethyl)-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dioneKi3100.0 [1], 12800.0 [2], 16500.0 [3], 26000.0 [4]
Urea, alpha-D-glucopyranosyl-Ki140000.0 [1], 7943280000000.0 [2]
2-Chloro-N-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]acetamideKi45000.0 [1], 25118900000000.0 [2]
1-Deoxy-1-methoxycarbamido-beta-D-gluco-2-heptulopyranosonamideKi16000.0 [1], 3162280000000.0 [2], 63095700000000.0 [3]
N-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]butanamideKi94000.0 [1], 10000000000000.0 [2]
N-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]propanamideKi39000.0 [1], 25118900000000.0 [2]
2-[(2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanylacetamideKi21100000.0 [1], 50118723363.0 [2]
2-Acetamido-N-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]acetamideKi990000.0 [1], 1000000000000.0 [2]
N-Phenyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanylacetamideKi3600000.0 [1], 251189000000.0 [2]
(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)-N'-methyloxane-2-carbohydrazideKi1800000.0 [1], 501187000000.0 [2]
N-(2,4-Difluorophenyl)-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanylacetamideKi18900000.0 [1], 50118723363.0 [2]
alpha-D-Glucopyranose, 5-thio-Ki2000000.0 [1], 501187000000.0 [2]
8,9,10-Trihydroxy-7-hydroxymethyl-2-thioxo-6-oxa-1,3-diaza-spiro[4.5]decan-4-oneKi5100.0 [1], 7000.0 [2]
3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-carboxylic acid hydrazideKi3000000.0 [1], 2511890000000.0 [2]
(5S,7S,8S,9S,10S)-8,9,10-Trihydroxy-7-(hydroxymethyl)-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dioneKi3000.0 [1], 316228000000000.0 [2]
(5S,7S,8S,9S,10S)-3-Amino-8,9,10-trihydroxy-7-(hydroxymethyl)-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dioneKi146000.0 [1], 6309570000000000.0 [2]
(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl)-acetonitrileKi9000000.0 [1], 100000000000.0 [2]
(6S,8S,9S,10S,11S)-9,10,11-Trihydroxy-8-(hydroxymethyl)-7-oxa-1,4-diazaspiro[5.5]undecane-2,5-dioneKi59700.0 [1], 15848900000000.0 [2]
(2S,3R,4R,5S,6R)-2-(Azidomethyl)-6-(hydroxymethyl)oxane-3,4,5-triolKi15200000.0 [1], 63095734448.0 [2]
Benzyl N-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]carbamateKi350000.0 [1], 3162280000000.0 [2]
(2R,3R,4R,5S,6R)-2-(Azidomethyl)-6-(hydroxymethyl)oxane-3,4,5-triolKi22400000.0 [1], 39810717055.0 [2]
2-[(2S,3R,4S,5S,6R)-2,3,4,5-Tetrahydroxy-6-(hydroxymethyl)oxan-2-yl]acetonitrileKi7600000.0 [1], 125893000000.0 [2]
1-Deoxy-1-methoxycarbamido-beta-D-glucopyranoseKi11749000000000.0 [1], 12589300000000.0 [2]
(5S,7S,8S,9S,10S)-3,8,9,10-Tetrahydroxy-7-(hydroxymethyl)-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dioneKi25118900000000.0 [1], 25704000000000.0 [2]
N-[(5S,7S,8S,9S,10S)-8,9,10-Trihydroxy-7-(hydroxymethyl)-2,4-dioxo-6-oxa-1,3-diazaspiro[4.5]decan-3-yl]acetamideKi1819700000000.0 [1], 1995260000000.0 [2]
(2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(1H-indol-2-yloxy)oxane-3,4,5-triolKi2600000.0 [1], 398107000000.0 [2]
alpha-D-Gluco-2-HeptulopyranoseKi15800000.0 [1], 63095734448.0 [2]
Methyl alpha-D-glucopyranosideKi79432823472.0 [1]
Methyl beta-D-glucopyranosideKi39810717055.0 [1]
1-Thio-beta-D-glucopyranoseKi1000000000000.0 [1]
3,4,5-Trihydroxy-6-(hydroxymethyl)oxane-2-carboxamideKi370000.0 [1]
2-Aminomethyl-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triolKi34500000.0 [1]
2-Amino-N-[(2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]acetamideKi370000.0 [1]
3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-carboxylic acid methyl esterKi24200000.0 [1]
2-Hydroxymethyl-6-mercapto-tetrahydro-pyran-3,4,5-triolKi1000000.0 [1]
Methanesulfonic acid 3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-ylmethyl esterKi4800000.0 [1]
N-Methyl-6-(hydroxymethyl)-3,4,5-trihydroxy-tetrahydro-2H-pyran-2-carboxamideKi160000.0 [1]
2,6-Bis-hydroxymethyl-tetrahydro-pyran-3,4,5-triolKi1500000.0 [1]
2-Bromo-N-[(2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]acetamideKi44000.0 [1]
3,4,5-Trihydroxy-6-(hydroxymethyl)-N-phenyloxane-2-carboxamideKi5400000.0 [1]
(2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxane-2-carboxamideKi2511890000000.0 [1]
(2R,3S,4S,5S,6S)-2-(Azidomethyl)-6-(hydroxymethyl)oxane-2,3,4,5-tetrolKi7400000.0 [1]
(2S,3S,4S,5S,6S)-N-Cyclopropyl-3,4,5-trihydroxy-6-(hydroxymethyl)oxane-2-carboxamideKi1300000.0 [1]
(2S,3S,4S,5S,6S)-3,4,5-Trihydroxy-N-(2-hydroxyethyl)-6-(hydroxymethyl)oxane-2-carboxamideKi2600000.0 [1]
3,4,5-Trihydroxy-6-(hydroxymethyl)-N-(4-hydroxyphenyl)oxane-2-carboxamideKi4400000.0 [1]
2-(2-Aminoethyl)-6-(hydroxymethyl)oxane-3,4,5-triolKi4500000.0 [1]
alpha-D-Glucopyranosyl-2-carboxylic acid amideKi2511890000000.0 [1]
N-BromoacetylglucopyranosylamineKi25118900000000.0 [1]
[(2S,3S,4S,5S,6S)-2,3,4,5-Tetrahydroxy-6-(hydroxymethyl)oxan-2-yl]methyl methanesulfonateKi3700000.0 [1]
(2S,3S,4S,5S,6S)-2,6-Bis(hydroxymethyl)oxane-2,3,4,5-tetrolKi15800000.0 [1]
(2S,3S,4S,5S,6S)-3,4,5-Trihydroxy-6-(hydroxymethyl)-N-(2,2,2-trifluoroethyl)oxane-2-carboxamideKi8100000.0 [1]
N-Benzyloxycarbonyl-glycyl-glycyl-hydroxamsaeureKi4.0 [1]
(2R,3R,4S,5S,6R)-2-(2-Hydroxyethoxy)-6-(hydroxymethyl)oxane-3,4,5-triolKi39810717055.0 [1]
(2S)-2-[[(2S)-2-(Phosphonoamino)propanoyl]amino]propanoic acidKi4.0 [1]
(2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-[2-(hydroxymethyl)phenoxy]oxane-3,4,5-triolKi125893000000.0 [1]
(2S)-2-[Acetyl(hydroxy)amino]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxopropan-2-yl]-4-methylpentanamideKi4.0 [1]
(2S)-N-[(2S)-1-[(2-Amino-2-oxoethyl)amino]-1-oxopropan-2-yl]-N'-hydroxy-2-methylpropanediamideKi4.0 [1]
Z-Gly-leu-NH2Ki4.0 [1]
(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxane-2-carbohydrazideKi316228000000.0 [1]
(2S,3R,4S,5S,6R)-N-[(2,4-Difluorophenyl)methyl]-3,4,5-trihydroxy-6-(hydroxymethyl)oxane-2-carboxamideKi39810717055.0 [1]
(2S,3R,4R,5S,6R)-2-(Aminomethyl)-6-(hydroxymethyl)oxane-3,4,5-triolKi63095734448.0 [1]
2,2,2-Trifluoro-N-[(2R,3S,4S,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]acetamideKi710000.0 [1]
alpha-IsomaltoseKi63095734448.0 [1]
(R)-2-Hydroxymethyl-6-methoxy-tetrahydro-pyran-3,4,5-triolKi24700000.0 [1]
Methyl (2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxane-2-carboxylateKi39810717055.0 [1]
2-Deoxy-2-fluoro-alpha-d-glucopyranosyl fluorideKi5011870000000.0 [1]
(5R,8R,9S)-8,9,10-Trihydroxy-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dioneKi10000000.0 [1]
(5S,8R,9S)-8,9,10-Trihydroxy-2-sulfanylidene-6-oxa-1,3-diazaspiro[4.5]decan-4-oneKi10000000.0 [1]
(5S,8R,9S)-8,9,10-Trihydroxy-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dioneKi11500000.0 [1]
3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-carboxylic acid amideKi440000.0 [1]
(5R,8S,9S)-8,9,10-Trihydroxy-7-(hydroxymethyl)-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dioneKi320000.0 [1]
(2S,4S,5S)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxane-2-carboxamideKi370000.0 [1]
6-Hydroxymethyl-tetrahydro-pyran-2,3,4,5-tetraolKi1700000.0 [1]
2,3,4,5-Tetrahydroxy-6-hydroxymethyl-tetrahydro-pyran-2-carboxylic acid amideKi3100000.0 [1]
Methyl N-[(2S)-2-carbamoyl-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]carbamateKi16000.0 [1]
(2R)-3,4,5-Trihydroxy-6-(hydroxymethyl)-N-methyloxane-2-carboxamideKi160000.0 [1]
(R)-2-Hydroxymethyl-6-methyl-tetrahydro-pyran-3,4,5-triolKi53100000.0 [1]
Benzyl N-[(2R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]carbamateKi350000.0 [1]
(2S)-2-(2-Aminoethyl)-6-(hydroxymethyl)oxane-3,4,5-triolKi4500000.0 [1]
((S)-3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl)-acetonitrileKi9000000.0 [1]
(2R)-3,4,5-Trihydroxy-6-(hydroxymethyl)-N-(4-hydroxyphenyl)oxane-2-carboxamideKi4400000.0 [1]
(2S)-3,4,5-Trihydroxy-6-(hydroxymethyl)-N-methyloxane-2-carboxamideKi36700000.0 [1]
(2R)-2-(Aminomethyl)-6-(hydroxymethyl)oxane-3,4,5-triolKi34500000.0 [1]
((S)-2,3,4,5-Tetrahydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl)-acetonitrileKi7600000.0 [1]
(S)-2-Azidomethyl-6-hydroxymethyl-tetrahydro-pyran-2,3,4,5-tetraolKi7400000.0 [1]
(2S)-3,4,5-Trihydroxy-N-(2-hydroxyethyl)-6-(hydroxymethyl)oxane-2-carboxamideKi16900000.0 [1]
(2S)-2-(Aminomethyl)-6-(hydroxymethyl)oxane-3,4,5-triolKi16800000.0 [1]
(2S)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxane-2-carboxylic acidKi15200000.0 [1]
(S)-3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-carboxylic acid methyl esterKi24200000.0 [1]
2-Bromo-N-[(2R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]acetamideKi44000.0 [1]
(R)-2-Azidomethyl-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triolKi22400000.0 [1]
(S)-2-Hydroxymethyl-6-mercapto-tetrahydro-pyran-3,4,5-triolKi1000000.0 [1]
(2S)-3,4,5-Trihydroxy-6-(hydroxymethyl)-N-(4-hydroxyphenyl)oxane-2-carboxamideKi5600000.0 [1]
(2R)-3,4,5-Trihydroxy-6-(hydroxymethyl)-N-phenyloxane-2-carboxamideKi5400000.0 [1]
(R)-2,6-Bis-hydroxymethyl-tetrahydro-pyran-3,4,5-triolKi1500000.0 [1]
(2S)-N-[(2,4-Difluorophenyl)methyl]-3,4,5-trihydroxy-6-(hydroxymethyl)oxane-2-carboxamideKi27200000.0 [1]
(2R)-3,4,5-Trihydroxy-6-(hydroxymethyl)-N-(2,2,2-trifluoroethyl)oxane-2-carboxamideKi8100000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Brain glycogen phosphorylase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/brain-glycogen-phosphorylase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 10). Quest Database™ Brain glycogen phosphorylase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/brain-glycogen-phosphorylase-inhibitors-ic50-ki.
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