Breast cancer type 1 susceptibility protein Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	[(2S)-2-Acetamido-3-[(2S)-2-[[(2S,3R)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	IC50	4600.0 [1]
	[(2S)-2-Acetamido-3-[(2S)-2-[[(2S,3R)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	Ki	1850.0 [1]
	[(2S)-2-Acetamido-3-[(2S)-2-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	IC50	3200.0 [1]
	[(2S)-2-Acetamido-3-[(2S)-2-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	Ki	1960.0 [1]
	(2S)-2-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-Acetamido-3-phosphonooxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoic acid	IC50	1000.0 [1]
	(2S)-2-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-Acetamido-3-phosphonooxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoic acid	Ki	270.0 [1]
	(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-Acetamido-3-phosphonooxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-3-phenylpropanoic acid	IC50	1600.0 [1]
	(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-Acetamido-3-phosphonooxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-3-phenylpropanoic acid	Ki	200.0 [1]
	3-(4-Methylpiperidin-1-yl)-10,10-dioxothioxanthen-9-one	Ki	39000.0 [1]
	1-(9,10,10-Trioxothioxanthen-3-yl)piperidine-4-carboxamide	Ki	30000.0 [1]
	3-(4-Benzylpiperidin-1-yl)-10,10-dioxothioxanthen-9-one	Ki	38000.0 [1]
	[(2S)-2-Amino-3-[(2S)-2-[[(2S,3R)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	IC50	10800.0 [1]
	2-[(2S)-2-Acetamido-3-[(2S)-2-[[(2S,3R)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl]propanedioic acid	IC50	52800.0 [1]
	[(2R,3S)-3-Acetamido-4-[(2S)-2-[[(2S,3R)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-oxobutan-2-yl] dihydrogen phosphate	IC50	250000.0 [1]
	[(2S)-2-Acetamido-3-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-oxopropyl] dihydrogen phosphate	IC50	15000.0 [1]
	[(2S)-2-Acetamido-3-[(2S)-2-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	IC50	35000.0 [1]
	[(2S)-2-Acetamido-3-[(2S)-2-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	IC50	30100.0 [1]
	[(2S)-2-Acetamido-3-[(2S)-2-[[(2S,3S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	IC50	7100.0 [1]
	[(2S)-2-Acetamido-3-[(2S)-2-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	IC50	18400.0 [1]
	[(2S)-2-Acetamido-3-[(2S)-2-[[(2S,3R)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	IC50	14900.0 [1]
	[(2S)-2-Acetamido-3-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-oxopropyl] dihydrogen phosphate	IC50	98400.0 [1]
	[(2S)-2-Acetamido-3-[(2S)-2-[(2S)-2-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	IC50	250000.0 [1]
	[(2R)-2-[[(2R)-2-[[(2R,3S)-2-[[(2R)-2-Acetamido-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-3-amino-3-oxopropyl] dihydrogen phosphate	IC50	250000.0 [1]
	(4S)-4-Acetamido-5-[(2S)-2-[[(2S,3R)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-oxopentanoic acid	IC50	250000.0 [1]
	(2S)-2-[[(2S)-3-Methyl-2-[[(2S)-1-[(2S)-2-(3-phenylpropanoylamino)-3-phosphonooxypropanoyl]pyrrolidine-2-carbonyl]amino]butanoyl]amino]-3-phenylpropanoic acid	Ki	100.0 [1]
	[(2S)-2-[[(2S)-2-Acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-[(2S)-2-[[(2S,3R)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	Ki	1240.0 [1]
	(2S)-2-[[(2S)-3-Methyl-2-[[(2S)-1-[(2S)-2-(5-phenylpentanoylamino)-3-phosphonooxypropanoyl]pyrrolidine-2-carbonyl]amino]butanoyl]amino]-3-phenylpropanoic acid	Ki	12050.0 [1]
	(2S)-2-[[(2S)-3-Methyl-2-[[(2S)-1-[(2S)-2-[(2-naphthalen-1-ylacetyl)amino]-3-phosphonooxypropanoyl]pyrrolidine-2-carbonyl]amino]butanoyl]amino]-3-phenylpropanoic acid	Ki	15670.0 [1]
	(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[3-(3,4-Dimethoxyphenyl)propanoylamino]-3-phosphonooxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-3-phenylpropanoic acid	Ki	4040.0 [1]
	(2S)-2-[[(2S)-3-Methyl-2-[[(2S)-1-[(2S)-2-[(3-phenylbenzoyl)amino]-3-phosphonooxypropanoyl]pyrrolidine-2-carbonyl]amino]butanoyl]amino]-3-phenylpropanoic acid	Ki	80.0 [1]
	[(2S)-2-[[(2R)-2-Acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-[(2S)-2-[[(2S,3R)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	Ki	19440.0 [1]
	[(2S)-2-[[(2S)-2-Acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-[(2S)-2-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	Ki	540.0 [1]
	(2S)-2-[[(2S)-3-Methyl-2-[[(2S)-1-[(2S)-2-(4-phenylbutanoylamino)-3-phosphonooxypropanoyl]pyrrolidine-2-carbonyl]amino]butanoyl]amino]-3-phenylpropanoic acid	Ki	500.0 [1]
	(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-Acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-phosphonooxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-3-phenylpropanoic acid	Ki	130.0 [1]
	(2S)-2-[[(2S)-3-Methyl-2-[[(2S)-1-[(2S)-2-[[(E)-4-phenylbut-3-enoyl]amino]-3-phosphonooxypropanoyl]pyrrolidine-2-carbonyl]amino]butanoyl]amino]-3-phenylpropanoic acid	Ki	40.0 [1]
	[(2S)-2-Acetamido-3-[(2S)-2-[[(2S,3R)-1-[[(2S)-1-amino-3-naphthalen-1-yl-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	IC50	171700.0 [1]
	[(2S)-2-Acetamido-3-[(2S)-2-[[(2S,3R)-1-[[(2S)-1-amino-3-naphthalen-2-yl-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	IC50	17700.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 37 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Breast cancer type 1 susceptibility protein Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/breast-cancer-type-1-susceptibility-protein-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Breast cancer type 1 susceptibility protein Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/breast-cancer-type-1-susceptibility-protein-inhibitors-ic50-ki.
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