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Bromodomain adjacent to zinc finger domain protein 2B Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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1-(7-(2-Methylsulfonyl-phenyl)-4-propoxy-1-aza-bicyclo[4.3.0]nona-2,4,6,8-tetraen-9-yl)-ethanoneIC50360.0 [1], 430.0 [2]
1-(8-Chloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)ethanoneIC5024000.0 [1], 37000.0 [2]
4,6-Dihydroxy-2-mercaptopyrimidineIC50279000.0 [1]
1-Methyl-2-pyrrolidinoneIC5034000000.0 [1]
Sgc-cbp30IC5020000.0 [1]
4'-(Imidazol-1-yl)acetophenoneIC50826000.0 [1]
4-[(2s,4r)-1-Acetyl-4-[(4-Chlorophenyl)amino]-2-Methyl-1,2,3,4-Tetrahydroquinolin-6-Yl]benzoic AcidIC5031622.78 [1]
1-(1,3,4,5-Tetrahydro-pyrido[4,3-b]indol-2-yl)-ethanoneIC5037000.0 [1]
2-Acetyl-8-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoleIC5026000.0 [1]
4-[(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-pyridin-2-ylbenzenesulfonamideKi3290.0 [1]
N-(5-Oxo-5,6,7,8-tetrahydronaphthalen-2-yl)acetamideIC50476000.0 [1]
3-[7-(Difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-N-methyl-1-(oxan-4-yl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxamideIC5018000.0 [1]
4-(4-(1-Methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-1H-imidazol-5-yl)benzonitrileIC50180.0 [1]
Pyrazine-2-carbothioamideIC50190000.0 [1]
4-[(2-Amino-3-chloro-4-hydroxy-5-methylphenyl)diazenyl]-N-pyridin-2-ylbenzenesulfonamideKi3300.0 [1]
N,2-Dimethyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)benzenesulfonamideIC50100000.0 [1]
N-Methyl-2-(Tetrahydro-2h-Pyran-4-Yloxy)benzamideIC5038000.0 [1]
4-{1-[2-(4-Methyl-1h-1,2,3-Triazol-1-Yl)ethyl]-4-Phenyl-1h-Imidazol-5-Yl}benzonitrileIC5026000.0 [1]
1-[1-(Pyridin-2-Yl)indolizin-3-Yl]ethan-1-OneIC507000.0 [1]
N-[3-(3-Methyl-4-Oxo-4,5,6,7-Tetrahydro-2h-Isoindol-1-Yl)-4-Phenoxyphenyl]methanesulfonamideIC501000.0 [1]
1-[2-(2,4-Difluorophenoxy)-5-methylsulfonylphenyl]-3-methyl-2,5,6,7-tetrahydropyrrolo[3,4-c]pyridin-4-oneIC501000.0 [1]
4-[5-(1-Methylpyrazol-4-yl)-3-[2-(4-methyltriazol-1-yl)ethyl]imidazol-4-yl]benzonitrileIC501070.0 [1]
1-(3-Phenylazanyl-1,4,6,7-Tetrahydropyrazolo[4,3-C]pyridin-5-Yl)ethanoneIC5020000.0 [1]
4-[3-[2-(4-Methyltriazol-1-yl)ethyl]-5-pyridin-4-ylimidazol-4-yl]benzonitrileIC504400.0 [1]
4-[3-[2-(4-Methyltriazol-1-yl)ethyl]-5-pyridin-3-ylimidazol-4-yl]benzonitrileIC5050000.0 [1]
4-[3-[2-(4-Methyltriazol-1-yl)ethyl]-5-(1,3-thiazol-5-yl)imidazol-4-yl]benzonitrileIC505250.0 [1]
4-[5-(3-Methyl-1,2-oxazol-5-yl)-3-[2-(4-methyltriazol-1-yl)ethyl]imidazol-4-yl]benzonitrileIC5050000.0 [1]
4-[3-[2-(4-Methyltriazol-1-yl)ethyl]imidazol-4-yl]benzonitrileIC5050000.0 [1]
4-[3-Methyl-5-(1-methylpyrazol-4-yl)imidazol-4-yl]benzonitrileIC5050000.0 [1]
3-Fluoro-4-[5-(1-methylpyrazol-4-yl)-3-[(4-methyltriazol-1-yl)methyl]imidazol-4-yl]benzonitrileIC50770.0 [1]
2-Fluoro-4-[5-(1-methylpyrazol-4-yl)-3-[(4-methyltriazol-1-yl)methyl]imidazol-4-yl]benzonitrileIC50790.0 [1]
4-Methyl-1-[[4-(1-methylpyrazol-4-yl)-5-(4-nitrophenyl)imidazol-1-yl]methyl]triazoleIC502450.0 [1]
1-[3-[7-(Difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-1-(oxan-4-yl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanoneIC5020000.0 [1]
1-[3-[2-Fluoro-4-(1-methylpyrazol-4-yl)anilino]-1-[(3R)-oxolan-3-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanoneIC5020000.0 [1]
3-(3-Acetylindolizin-1-yl)benzamideIC509800.0 [1]
1-[1-[2-(Hydroxymethyl)phenyl]indolizin-3-yl]ethanoneIC501000.0 [1]
1-[1-[4-(Hydroxymethyl)phenyl]indolizin-3-yl]ethanoneIC504100.0 [1]
1-[1-[4-(Dimethylamino)phenyl]indolizin-3-yl]ethanoneIC503800.0 [1]
1-[1-(2-Methylsulfonylphenyl)indolizin-3-yl]ethanoneIC501300.0 [1]
1-[1-[2-(Hydroxymethyl)phenyl]-7-methylindolizin-3-yl]ethanoneIC50370.0 [1]
1-[1-[2-(Hydroxymethyl)phenyl]-7-methoxyindolizin-3-yl]ethanoneIC50410.0 [1]
1-[1-[2-(Hydroxymethyl)phenyl]-7-morpholin-4-ylindolizin-3-yl]ethanoneIC50540.0 [1]
3-Acetyl-1-[2-(hydroxymethyl)phenyl]indolizine-7-carboxamideIC501900.0 [1]
1-[7-Methoxy-1-(2-methylsulfonylphenyl)indolizin-3-yl]ethanoneIC50820.0 [1]
1-[1-(3-Methoxyphenyl)indolizin-3-yl]ethanoneIC5030000.0 [1]
1-[1-(2-Hydroxyphenyl)indolizin-3-yl]ethanoneIC5022700.0 [1]
1-[1-(3-Hydroxyphenyl)indolizin-3-yl]ethanoneIC5012500.0 [1]
1-[7-Methyl-1-(2-methylsulfonylphenyl)indolizin-3-yl]ethanoneIC501900.0 [1]
1-[1-[2-(Hydroxymethyl)-4-methoxyphenyl]indolizin-3-yl]ethanoneIC501500.0 [1]
Tert-butyl N-[[3-acetyl-1-(2-methylsulfonylphenyl)indolizin-7-yl]methyl]carbamateIC50670.0 [1]
1-(1-Thiophen-2-ylindolizin-3-yl)ethanoneIC5034100.0 [1]
1-[3-(2-Methylsulfonylphenyl)-5-propoxyindol-1-yl]ethanoneIC508550.0 [1]
4-[(E)-(2-Amino-4-Hydroxy-3,5-Dimethylphenyl)diazenyl]-N-(Pyridin-2-Yl)benzenesulfonamideKi2260.0 [1]
3-[(1-Acetyl-5-methoxyindole-3-carbonyl)amino]-5-(furan-2-yl)benzoic acidIC5012160.0 [1]
3-[(1-Acetyl-5-methoxyindole-3-carbonyl)amino]-4-fluoro-5-(1-methylpyrazol-4-yl)benzoic acidIC5020000.0 [1]
3-[(1-Acetylindole-3-carbonyl)amino]-4-fluorobenzoic acidIC5020000.0 [1]
3-[(1-Acetylindole-3-carbonyl)amino]benzoic acidIC5020000.0 [1]
3-[(1-Acetylindole-3-carbonyl)amino]-5-(oxan-2-yloxymethyl)benzoic acidIC5020000.0 [1]
3-[(1-Acetyl-5-methoxyindole-3-carbonyl)amino]-5-(1-methylpyrazol-4-yl)benzoic acidIC5020000.0 [1]
3-[(1-Acetylindole-3-carbonyl)amino]-5-(furan-2-yl)benzoic acidIC501690.0 [1]
N,N,2-Trimethyl-5-(3-methyl-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)benzenesulfonamideIC50100000.0 [1]
N,1,5-Trimethyl-1H-pyrazole-3-carboxamideIC501094000.0 [1]
N-Methyl-6-phenylpyridine-3-carboxamideIC50109000.0 [1]
N-Methyl-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxamideIC50241000.0 [1]
2-Methyl-1H-imidazole-4-carbothioamideIC50495000.0 [1]
2-Acetyl-8-methoxy-2,3,4,5-tetrahydro-1H-pyrido[4,3-B]indoleIC5036000.0 [1]
2-Acetyl-8-bromo-2,3,4,5-tetrahydro-1H-pyrido[4,3-B]indoleIC5012000.0 [1]
2-Acetyl-8-fluoro-2,3,4,5-tetrahydro-1H-pyrido[4,3-B]indoleIC50102000.0 [1]
N-Methyl-8-chloro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-2-carboxamideIC509000.0 [1]
N-[2-Methyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)phenyl]methanesulfonamideIC50100000.0 [1]
N-[2-Methyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)phenyl]propanamideIC50100000.0 [1]
1-{1-[2-(Hydroxymethyl)phenyl]-7-Phenoxyindolizin-3-Yl}ethanoneIC50610.0 [1]
1-{1-[2-(Methylsulfonyl)phenyl]-7-Phenoxyindolizin-3-Yl}ethanoneIC50840.0 [1]
2H-Pyrido[4,3-b]indole-2-carbothioamide, 8-chloro-1,3,4,5-tetrahydro-IC502000000.0 [1]
3-(2-Acetyl-8-chloro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)-N-methylpropanamideIC50143000.0 [1]
2-(2-Acetyl-8-chloro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)-N-methylacetamideIC5069000.0 [1]
1-(8-Chloro-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)ethanoneIC5025000.0 [1]
2-Acetyl-N-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indole-8-sulfonamideIC5055000.0 [1]
N-(2-Acetyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-8-yl)methanesulfonamideIC501000000.0 [1]
2-(2-Acetyl-8-chloro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)acetic acidIC50152000.0 [1]
2-Acetyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-sulfonamideIC5046000.0 [1]
3-(2-Acetyl-8-chloro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)propanoic acidIC5066000.0 [1]
N-Ethyl-2-acetyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-sulfonamideIC5050000.0 [1]
1-(5-Acetyl-8-bromo-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)ethanoneIC5037000.0 [1]
8-Bromo-N-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indole-2-carboxamideIC5014000.0 [1]
N-(1-Acetyl-1h-Indol-3-Yl)-N-(5-Hydroxy-2-Methylphenyl)-3-(Trifluoromethyl)benzamideIC5027000.0 [1]
1-[1-(Imidazo[1,2-A]pyridin-5-Yl)-7-(Morpholin-4-Yl)indolizin-3-Yl]ethanoneIC50100000.0 [1]
1-(7-Propoxy-1-pyridin-2-ylindolizin-3-yl)ethanoneIC502511.89 [1]
1-[1-(6-Methylpyridin-2-yl)-7-morpholin-4-ylindolizin-3-yl]ethanoneIC5015848.93 [1]
1-[7-(Morpholin-4-Yl)-1-(Pyridin-2-Yl)indolizin-3-Yl]ethanoneIC503162.28 [1]
Items per page: 1 - 10 of 90
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References

This online tool may be cited as follows

MLA

"Quest Database™ Bromodomain adjacent to zinc finger domain protein 2B Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 25 Apr. 2024, https://www.aatbio.com/data-sets/bromodomain-adjacent-to-zinc-finger-domain-protein-2b-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, April 25). Quest Database™ Bromodomain adjacent to zinc finger domain protein 2B Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/bromodomain-adjacent-to-zinc-finger-domain-protein-2b-inhibitors-ic50-ki.
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