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C-C chemokine receptor type 6 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
CCR6 inhibitor 1IC506.0 [1], 30.0 [2]
4-[4-[4-[[5-(Trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]benzonitrileIC5017.0 [1], 36.0 [2]
4-[4-[4-[[5-(Trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]benzamideIC5013.0 [1], 41.0 [2]
6-[[4-[4-(4-Tert-butylphenyl)phenyl]sulfonylcyclohexyl]amino]pyridine-3-carbonitrileIC50140.0 [1], 30000.0 [2]
6-[[1-(4-Phenylphenyl)sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrileIC50240.0 [1], 290.0 [2]
5-[4-[4-[[5-(Trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]pyridine-2-carboxamideIC5017.0 [1], 42.0 [2]
6-{[1-(4-Methylbenzenesulfonyl)piperidin-4-yl]amino}pyridine-3-carbonitrileIC501400.0 [1], 3100.0 [2]
Rediocide AIC50261.0 [1]
5-Butyl-9-[1-(4,6-dimethylpyrimidine-5-carbonyl)-4-methylpiperidin-4-yl]-3-[(4-ethoxycyclohexyl)methyl]-3,9-diazaspiro[5.5]undecan-4-oneIC5050000.0 [1]
PharmaGSID_48521IC5050000.0 [1]
1-[4-Chloro-2-hydroxy-3-[(3S)-3-methyloxolan-3-yl]sulfonylphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]ureaIC5010000.0 [1]
N-[5-Chloro-2-[(E)-3-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-3-oxoprop-1-enyl]phenyl]acetamideIC50100000.0 [1]
3-[4-[4-[[5-(Trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]benzonitrileIC5031.0 [1]
6-[[1-[4-(4-Cyanophenyl)phenyl]sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrileIC5012000.0 [1]
2-[[1-(4-Methoxyphenyl)sulfonylpiperidin-4-yl]amino]pyridine-4-carbonitrileIC5030000.0 [1]
N-[1-(4-Methoxyphenyl)sulfonylpiperidin-4-yl]-5-methylpyridin-2-amineIC5021000.0 [1]
N-[1-(4-Phenylphenyl)sulfonylpiperidin-4-yl]-5-(trifluoromethyl)pyridin-2-amineIC50170.0 [1]
6-[[1-[4-(Trifluoromethyl)phenyl]sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrileIC50800.0 [1]
N-[4-[4-[4-[(5-Cyanopyridin-2-yl)amino]piperidin-1-yl]sulfonylphenyl]phenyl]acetamideIC5030000.0 [1]
6-[[1-[4-(3-Phenylphenyl)phenyl]sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrileIC5030000.0 [1]
2-[4-[4-[[5-(Trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]benzonitrileIC5048.0 [1]
6-[[1-[4-(3-Methylphenyl)phenyl]sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrileIC5030000.0 [1]
N-[4-(4-Pyridin-4-ylphenyl)sulfonylcyclohexyl]-5-(trifluoromethyl)pyridin-2-amineIC5024.0 [1]
6-[[4-(4-Phenylphenyl)sulfonylcyclohexyl]amino]pyridine-3-carbonitrileIC50190.0 [1]
2-[4-[4-[[5-(Trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]benzamideIC50900.0 [1]
4-[[1-(4-Methoxyphenyl)sulfonylpiperidin-4-yl]amino]benzonitrileIC501900.0 [1]
6-[[1-(4-Methoxyphenyl)sulfonylpiperidin-4-yl]amino]pyridine-2-carbonitrileIC507400.0 [1]
6-[[1-(4-Methoxyphenyl)sulfonylazepan-4-yl]amino]pyridine-3-carbonitrileIC5017000.0 [1]
N-[4-(4-Phenylphenyl)sulfonylcyclohexyl]-5-(trifluoromethyl)pyridin-2-amineIC5076.0 [1]
N-[4-(4-Pyridin-3-ylphenyl)sulfonylcyclohexyl]-5-(trifluoromethyl)pyridin-2-amineIC5048.0 [1]
1-(4-Methoxyphenyl)sulfonyl-N-phenylpiperidin-4-amineIC5012000.0 [1]
3-[4-[4-[[5-(Trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]benzamideIC5012.0 [1]
5-[4-[4-[[5-(Trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]pyridine-2-carbonitrileIC5027.0 [1]
6-[[1-(4-Chlorophenyl)sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrileIC501500.0 [1]
6-[[1-(4-Tert-butylphenyl)sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrileIC50220.0 [1]
N-[4-(4-Pyridin-2-ylphenyl)sulfonylcyclohexyl]-5-(trifluoromethyl)pyridin-2-amineIC50460.0 [1]
6-[[1-(4-Hydroxyphenyl)sulfonylpyrrolidin-3-yl]amino]pyridine-3-carbonitrileIC5030000.0 [1]
N-[1-(4-Methoxyphenyl)sulfonylpiperidin-4-yl]-5-(trifluoromethyl)pyridin-2-amineIC50940.0 [1]
6-{[1-(4-Methoxybenzenesulfonyl)piperidin-4-yl]amino}pyridine-3-carbonitrileIC502500.0 [1]
N-(4-Methoxyphenyl)-1-(4-methoxyphenyl)sulfonylpiperidin-4-amineIC5030000.0 [1]
N-[4-(2-Cyanopyrrol-1-yl)-1-(4-methylpiperidin-1-yl)-1-oxobutan-2-yl]-1H-indole-4-sulfonamideIC5010000.0 [1]
4-Amino-3,5-dichloro-N-[4-(2-cyanopyrrol-1-yl)-1-(4-methylpiperidin-1-yl)-1-oxobutan-2-yl]benzenesulfonamideIC5010000.0 [1]
6-Chloro-2-hydroxy-N,N-dimethyl-3-[[2-[[(5-methylfuran-2-yl)-(3-methyloxetan-3-yl)methyl]amino]-3,4-dioxocyclobuten-1-yl]amino]benzenesulfonamideIC503.4 [1]
Methyl (2R)-1-[2-hydroxy-3-[[2-[[(R)-(5-methylfuran-2-yl)-(3-methyloxetan-3-yl)methyl]amino]-3,4-dioxocyclobuten-1-yl]amino]benzoyl]pyrrolidine-2-carboxylateIC505.8 [1]
2-Hydroxy-N,N-dimethyl-3-[[2-[[(R)-(5-methylfuran-2-yl)-(3-methyloxetan-3-yl)methyl]amino]-3,4-dioxocyclobuten-1-yl]amino]benzamideIC501.4 [1]
3-[4-Chloro-2-hydroxy-3-(4-methylpiperazin-1-yl)sulfonylanilino]-4-[[(R)-(5-methylfuran-2-yl)-(3-methyloxetan-3-yl)methyl]amino]cyclobut-3-ene-1,2-dioneIC501.9 [1]
Items per page: 1 - 10 of 46
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References

This online tool may be cited as follows

MLA

"Quest Database™ C-C chemokine receptor type 6 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/c-c-chemokine-receptor-type-6-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ C-C chemokine receptor type 6 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/c-c-chemokine-receptor-type-6-inhibitors-ic50-ki.
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