 | Amg-487 | IC50 | 15.0 [1] |
| Amg-487 | Ki | 39.81 [1], 158.49 [2] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 115.0 [1] |
 | N-(2-Ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-[(1R)-1-[4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]pyrido[2,3-d]pyrimidin-2-yl]ethyl]acetamide | IC50 | 0.4 [1], 0.6 [2], 0.8 [3], 15.0 [4] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)imidazo[1,2-a]pyrimidin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 643.0 [1] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide | IC50 | 47.0 [1], 129.0 [2] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-4-oxopyrido[1,2-a]pyrimidin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 2.0 [1], 17.0 [2], 41.0 [3] |
 | (6Ar,9R)-9-N,9-N-diethyl-7-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7,9-dicarboxamide | IC50 | 18.0 [1], 51.0 [2], 54.0 [3], 74.0 [4] |
 | 1-(4-Chlorophenyl)-2-(2-imino-3-methyl-benzimidazol-1-yl)ethanone | IC50 | 800.0 [1], 9000.0 [2] |
 | N-[(1R)-1-[3-(4-Ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-[(1-oxidopyridin-1-ium-3-yl)methyl]-2-[4-(trifluoromethoxy)phenyl]acetamide | IC50 | 4.0 [1], 7.0 [2], 14.0 [3], 58.0 [4] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-8-cyclopropylimidazo[1,2-a]pyrazin-2-yl]ethyl]-N-[(1,1-dioxothian-4-yl)methyl]-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide | IC50 | 0.9 [1], 7.3 [2], 18.9 [3], 21.0 [4] |
 | 5-Chloro-6-(4-(1-(4-cyanobenzyl)piperidin-4-yl)piperazin-1-yl)-N-(2-phenoxyethyl)nicotinamide | IC50 | 20.0 [1], 45.0 [2], 85.0 [3] |
| 5-Chloro-6-(4-(1-(4-cyanobenzyl)piperidin-4-yl)piperazin-1-yl)-N-(2-phenoxyethyl)nicotinamide | Ki | 110.0 [1] |
 | N-[(1R)-1-[3-(4-Chlorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-[(1,1-dioxothian-4-yl)methyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 6.0 [1], 9.8 [2], 12.0 [3], 45.0 [4] |
 | 4-[[1-(2,3-Dihydro-1-benzofuran-5-yl)ethyl-[[4-[2-(2,5-dioxopyrrolidin-1-yl)ethoxy]-3-methoxyphenyl]methyl]amino]methyl]cyclohexane-1-carboxylic acid | IC50 | 60.0 [1], 760.0 [2] |
 | 4-[[(5-Chloro-2,3-dihydro-1H-inden-1-yl)-[[4-[2-(2,5-dioxopyrrolidin-1-yl)ethoxy]-3-methoxyphenyl]methyl]amino]methyl]cyclohexane-1-carboxylic acid | IC50 | 24.0 [1], 64.0 [2], 1660.0 [3] |
 | N-[(1R)-1-[3-(4-Ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(pyridin-3-ylmethyl)acetamide | IC50 | 5.0 [1], 20.0 [2] |
| N-[(1R)-1-[3-(4-Ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(pyridin-3-ylmethyl)acetamide | Ki | 10.0 [1] |
 | 3-Amino-6-chloro-5-[(3S)-4-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-3-ethylpiperazin-1-yl]pyrazine-2-carboxamide | IC50 | 0.8 [1] |
| 3-Amino-6-chloro-5-[(3S)-4-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-3-ethylpiperazin-1-yl]pyrazine-2-carboxamide | Ki | 0.4 [1] |
 | CXCR3 Antagonist 6c | IC50 | 20.0 [1], 60.0 [2], 100.0 [3] |
 | (S)-5-Chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)-3-ethylpiperazin-1-yl)-N-ethylnicotinamide | IC50 | 0.3 [1] |
| (S)-5-Chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)-3-ethylpiperazin-1-yl)-N-ethylnicotinamide | Ki | 3.16 [1] |
 | 1-(4-Chlorophenyl)-2-(4-ethyl-2-imino-3-methylbenzimidazol-1-yl)ethanone | IC50 | 30.0 [1], 70.0 [2] |
 | N-[2-(Dimethylamino)ethyl]-N-[1-[3-(4-fluorophenyl)-4-oxoquinazolin-2-yl]ethyl]decanamide | IC50 | 250.0 [1], 500.0 [2], 3200.0 [3] |
 | N-[(1R)-1-[3-(4-Ethoxyphenyl)-4-oxoquinazolin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethoxy)phenyl]acetamide | IC50 | 6.0 [1], 7.0 [2], 140.0 [3] |
 | N-[(1R)-1-[1-(4-Cyanophenyl)-4-phenylimidazol-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 0.7 [1], 14.0 [2] |
 | N-[(1R)-1-[3-(4-Ethoxyphenyl)-4-oxoquinazolin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(pyridin-3-ylmethyl)acetamide | IC50 | 1.0 [1], 3.0 [2], 20.0 [3] |
 | N-[(1R)-1-[3-(4-Ethoxyphenyl)-4-oxoquinazolin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethyl)phenyl]acetamide | IC50 | 6.0 [1], 350.0 [2] |
 | N-[(1R)-1-[3-(4-Chlorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-[(1,1-dioxothian-4-yl)methyl]-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide | IC50 | 7.0 [1], 13.0 [2], 55.0 [3] |
 | N-[(1,1-Dioxothian-4-yl)methyl]-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide | IC50 | 7.0 [1], 22.0 [2], 90.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)quinolin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 0.8 [1], 21.0 [2], 72.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-1,8-naphthyridin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 2.0 [1], 27.0 [2], 48.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-8-methyl-4-oxo-6,7-dihydro-5H-pyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 4.0 [1], 60.0 [2], 88.0 [3] |
 | N-[(1R)-1-[1-(4-Cyanophenyl)benzimidazol-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 6.0 [1], 35.0 [2], 521.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)imidazo[1,2-a]pyridin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 21.0 [1], 72.0 [2] |
| N-[(1R)-1-[3-(4-Cyanophenyl)imidazo[1,2-a]pyridin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | Ki | 3.0 [1] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-7-methylimidazo[1,2-a]pyrimidin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 2.0 [1], 22.0 [2], 100.0 [3] |
 | N-[1-[8-Chloro-3-(4-cyanophenyl)imidazo[1,2-a]pyrazin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide | IC50 | 3.0 [1], 20.0 [2], 57.0 [3] |
 | N-[1-[3-(4-Cyanophenyl)-8-methoxyimidazo[1,2-a]pyrazin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide | IC50 | 2.0 [1], 17.0 [2], 18.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-8-methoxyimidazo[1,2-a]pyrazin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide | IC50 | 0.9 [1], 6.0 [2], 7.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-8-methylimidazo[1,2-a]pyrazin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide | IC50 | 1.6 [1], 10.0 [2], 44.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-8-ethylimidazo[1,2-a]pyrazin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide | IC50 | 1.1 [1], 11.0 [2], 12.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-8-cyclopropylimidazo[1,2-a]pyrazin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide | IC50 | 0.9 [1], 16.0 [2], 17.0 [3] |
 | N-[1-[3-(4-Cyanophenyl)-8-(dimethylamino)imidazo[1,2-a]pyrazin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide | IC50 | 1.4 [1], 27.0 [2], 45.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-8-cyclopropylimidazo[1,2-a]pyrazin-2-yl]ethyl]-N-[(1,1-dioxothian-4-yl)methyl]-2-[4-(trifluoromethoxy)phenyl]acetamide | IC50 | 1.1 [1], 13.0 [2], 34.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-8-cyclopropylimidazo[1,2-a]pyrazin-2-yl]ethyl]-N-[(1,1-dioxothian-4-yl)methyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 0.9 [1], 21.0 [2], 25.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-8-cyclopropylimidazo[1,2-a]pyrazin-2-yl]ethyl]-N-[(1,1-dioxothian-4-yl)methyl]-2-[3-(trifluoromethyl)phenyl]acetamide | IC50 | 1.7 [1], 29.0 [2], 36.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-8-cyclopropylimidazo[1,2-a]pyrazin-2-yl]ethyl]-N-[(1,1-dioxothian-4-yl)methyl]-2-[4-(trifluoromethyl)phenyl]acetamide | IC50 | 1.3 [1], 16.0 [2], 22.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-8-cyclopropylimidazo[1,2-a]pyrazin-2-yl]ethyl]-N-[(1,1-dioxothian-4-yl)methyl]-2-[3-(trifluoromethoxy)phenyl]acetamide | IC50 | 1.1 [1], 25.0 [2], 75.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-7-methyl-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 4.0 [1], 12.0 [2], 30.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-7-methoxy-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 4.0 [1], 10.0 [2], 22.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-7-methoxy-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide | IC50 | 3.0 [1], 7.0 [2], 18.0 [3] |
 | (6Ar,9R)-9-(4-hydroxypiperidine-1-carbonyl)-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide | IC50 | 5.0 [1], 14.0 [2], 200.0 [3] |
 | (6Ar,9R)-N-phenyl-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide | IC50 | 4.0 [1], 5.0 [2], 700.0 [3] |
 | (6Ar,9R)-N-phenyl-9-(piperidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide | IC50 | 5.0 [1], 9.0 [2], 840.0 [3] |
 | N-[(1,1-Dioxothian-4-yl)methyl]-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 7.0 [1], 17.0 [2], 72.0 [3] |
 | N-[(1R)-1-[3-(4-Chlorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide | IC50 | 7.0 [1], 21.0 [2], 107.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-[(1,1-dioxothian-4-yl)methyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 8.0 [1], 12.0 [2], 39.0 [3] |
 | N-(2-Ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide | IC50 | 47.0 [1], 58.0 [2], 292.0 [3] |
 | N-[(1R)-1-[3-(4-Chlorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 6.0 [1], 22.0 [2], 102.0 [3] |
 | N-(2-Ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 42.0 [1], 50.0 [2], 254.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-[(1,1-dioxothian-4-yl)methyl]-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide | IC50 | 7.0 [1], 15.0 [2], 37.0 [3] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)-4-oxopyrido[1,2-a]pyrimidin-2-yl]ethyl]-N-[(1,1-dioxothian-4-yl)methyl]-2-[4-(trifluoromethoxy)phenyl]acetamide | IC50 | 6.0 [1], 22.0 [2], 60.0 [3] |
 | N-[(Z)-1-(3-Acetamidophenyl)ethylideneamino]-4-[[benzyl-(4-chlorophenyl)sulfonylamino]methyl]benzamide | IC50 | 538.0 [1] |
| N-[(Z)-1-(3-Acetamidophenyl)ethylideneamino]-4-[[benzyl-(4-chlorophenyl)sulfonylamino]methyl]benzamide | Ki | 211.0 [1], 348.0 [2] |
 | 4-[[[(1S)-1-(4-Chlorophenyl)ethyl]-[[4-[2-(2,5-dioxopyrrolidin-1-yl)ethoxy]-3-methylphenyl]methyl]amino]methyl]cyclohexane-1-carboxylic acid | IC50 | 32.0 [1], 38.0 [2], 3810.0 [3] |
 | (4-Chlorophenyl)methyl-[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl]-dimethylazanium | Ki | 199.53 [1], 501.19 [2] |
 | [4-(3-Chlorophenyl)phenyl]methyl-[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl]-dimethylazanium | Ki | 125.89 [1], 251.19 [2], 316.23 [3] |
 | 5-Chloro-6-[(3S)-4-[1-[(4-chloro-2-fluorophenyl)methyl]piperidin-4-yl]-3-ethylpiperazin-1-yl]-N-ethylpyridine-3-carboxamide | IC50 | 0.2 [1] |
 | 5-Chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)piperazin-1-yl)-N-(3,4-dichlorobenzyl)nicotinamide | IC50 | 35.0 [1] |
| 5-Chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)piperazin-1-yl)-N-(3,4-dichlorobenzyl)nicotinamide | Ki | 35.0 [1] |
 | N-[(1R)-1-[3-(4-Hydroxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethoxy)phenyl]acetamide | IC50 | 4.1 [1], 816.0 [2] |
 | 3-[1-[(4-Bromophenyl)methyl]piperidin-4-yl]-3-phenylpiperidine-2,6-dione | IC50 | 330.0 [1], 1330.0 [2] |
 | 2-(2-Acetylbenzimidazol-1-yl)-1-(4-nitrophenyl)ethanone | IC50 | 3000.0 [1] |
 | 1-(4-Iodophenyl)-3-(2-adamantyl)guanidine | Ki | 3981.07 [1] |
 | 1-[3,5-Bis(trifluoromethyl)phenyl]-3-[1-[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl]piperidin-4-yl]urea | Ki | 26.0 [1], 73.0 [2] |
 | 1-[1-[[(1R,5S)-6,6-Dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl]piperidin-4-yl]-3-[3-fluoro-5-(trifluoromethyl)phenyl]urea | Ki | 16.0 [1] |
 | N-[1-[[(1R,5S)-6,6-Dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl]piperidin-4-yl]-N-methyl-1,3-benzothiazol-2-amine | Ki | 126.0 [1], 140.0 [2] |
 | 1-[1-[(9-Acetyl-9-azabicyclo[3.3.1]non-2-en-3-yl)methyl]piperidin-4-yl]-3-[3-fluoro-5-(trifluoromethyl)phenyl]urea | Ki | 9.0 [1] |
 | 5-Chloro-6-[4-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]piperazin-1-yl]-N-methylpyridine-3-carboxamide | IC50 | 560.0 [1] |
| 5-Chloro-6-[4-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]piperazin-1-yl]-N-methylpyridine-3-carboxamide | Ki | 560.0 [1] |
 | 5-Chloro-6-[4-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]piperidin-1-yl]-N-[(3,4-dichlorophenyl)methyl]pyridine-3-carboxamide | IC50 | 4500.0 [1] |
| 5-Chloro-6-[4-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]piperidin-1-yl]-N-[(3,4-dichlorophenyl)methyl]pyridine-3-carboxamide | Ki | 4500.0 [1] |
 | N-[(1R)-1-[3-(4-Ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 1.0 [1], 22.0 [2] |
 | 1-(1-(Cyclooctenylmethyl)piperidin-4-yl)-3-(naphthalen-2-yl)urea | Ki | 110.0 [1] |
 | N-[(1R)-1-[1-(4-Ethoxyphenyl)-4-phenylimidazol-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(pyridin-3-ylmethyl)acetamide | IC50 | 11.0 [1], 91.0 [2] |
 | (6Ar,9R)-9-(azetidine-1-carbonyl)-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide | IC50 | 8.0 [1], 61.0 [2] |
 | 1-[2-[4-[[1-(2,3-Dihydro-1-benzofuran-5-yl)ethyl-methylamino]methyl]-2-methoxyphenoxy]ethyl]pyrrolidine-2,5-dione | IC50 | 74.0 [1], 403.0 [2] |
 | N-[2-[7-Chloro-3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]ethyl]-N-methyl-2-phenylacetamide | IC50 | 300.0 [1], 400.0 [2] |
 | 1-(4-Chlorophenyl)-2-(2-imino-3,4-dimethylbenzimidazol-1-yl)ethanone | IC50 | 80.0 [1], 100.0 [2] |
 | N-[(1R)-1-[1-(4-Cyanophenyl)-4-cyclopropyl-5-(difluoromethyl)imidazol-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 12.0 [1], 18.0 [2] |
 | N-[(1R)-1-[5-Chloro-1-(4-cyanophenyl)-4-cyclopropylimidazol-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 7.8 [1], 24.0 [2] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)quinoxalin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 9.0 [1], 121.0 [2] |
 | N-[(1R)-1-[2-(4-Cyanophenyl)quinolin-3-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 5.0 [1], 115.0 [2] |
 | N-[(1R)-1-[3-(4-Cyanophenyl)pyrazolo[1,5-a]pyridin-2-yl]ethyl]-N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide | IC50 | 18.0 [1], 523.0 [2] |
 | N-[3-[7-Chloro-3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]propyl]-N-methylnaphthalene-2-carboxamide | IC50 | 15.0 [1], 40.0 [2] |
 | N-[3-[7-Chloro-3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]propyl]-N,2,2-trimethylpropanamide | IC50 | 400.0 [1], 600.0 [2] |
 | N-[3-[3-[2-(4-Chlorophenyl)-2-oxoethyl]-7-ethyl-2-iminobenzimidazol-1-yl]propyl]-N-methyl-2-phenylacetamide | IC50 | 100.0 [1], 200.0 [2] |
 | N-[4-[7-Chloro-3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]butyl]-N-methyl-2-phenylacetamide | IC50 | 400.0 [1] |
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