C5a anaphylatoxin chemotactic receptor Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	CID 6918468	IC50	29.0 [1], 31.0 [2], 104.0 [3]
	N,N-Bis(1,3-benzodioxol-5-ylmethyl)-3-butyl-2,5-diphenylimidazol-4-amine	IC50	1.0 [1]
	(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-Amino-2-[[(2S)-2-(methylamino)-3-phenylpropanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-cyclohexylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	IC50	700.0 [1], 11000.0 [2], 11220.18 [3]
	2-(2,6-Diethylphenyl)-4-methoxy-N-methyl-N-phenyl-5,6,7,8-tetrahydroquinolin-5-amine	IC50	7900.0 [1]
	2-(2,6-Diethylphenyl)-4-methoxy-N-methyl-N-phenyl-5,6,7,8-tetrahydroquinolin-5-amine	Ki	680.0 [1]
	N-[2-(Cyclopentylamino)-1-(2-fluorophenyl)-2-oxoethyl]-N-(2,4-dimethoxyphenyl)furan-2-carboxamide	IC50	79.43 [1], 125.89 [2], 251.19 [3], 3162.28 [4]
	N-[2-(Cyclopentylamino)-1-(2-fluorophenyl)-2-oxoethyl]-N-(2,4-dimethoxyphenyl)benzamide	IC50	25.12 [1], 31.62 [2], 39.81 [3], 794.33 [4]
	n,n'-1,2-Phenylenebis(n,4-dimethylbenzenesulfonamide)	IC50	6.7 [1], 200.0 [2]
	[(4-Methylphenyl)sulfonyl](2-{[(4-methylphenyl)sulfonyl]prop-2-enylamino}pheny l)prop-2-enylamine	IC50	59.0 [1], 300.0 [2]
	N,4-Dimethyl-N-(2-(thiophene-3-carbonyl)phenyl)benzenesulfonamide	IC50	400.0 [1], 600.0 [2], 1700.0 [3]
	(4S)-N-[(2S)-1-[[(2S)-5-Amino-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-(4-fluorophenyl)-1-oxopropan-2-yl]amino]-5-methyl-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2,6-dioxo-1,3-diazinane-4-carboxamide	IC50	39.0 [1], 41.0 [2], 111.0 [3]
	N-[[4-(Dimethylamino)phenyl]methyl]-7-methoxy-N-(4-propan-2-ylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide	IC50	2.0 [1], 3.0 [2]
	Methyl{2-[methyl(phenylsulfonyl)amino]phenyl}(phenylsulfonyl)amine	IC50	60000.0 [1]
	1,4-Ditosylpiperazine	IC50	60000.0 [1]
	Ishkdmqlgr	IC50	1000000.0 [1]
	Ishkdmqlgr	Ki	300000.0 [1]
	(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-Amino-2-[[(2S)-2-(methylamino)-3-phenylpropanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-cyclohexylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	IC50	1995.26 [1], 2000.0 [2]
	N-(4-Chlorophenethyl)-N-((1r,4r)-4-hydroxycyclohexyl)-1-naphthamide	IC50	125.0 [1]
	(2S)-2-[[2-[[(2S)-2-[[(2S)-5-Amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]-3-carboxypropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-oxopentanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoic acid	Ki	300000.0 [1]
	(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-3-cyclohexylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	IC50	4786.3 [1], 4800.0 [2]
	(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-5-aminopentanoyl]pyrrolidine-2-carbonyl]amino]-3-cyclohexylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	IC50	794.33 [1], 800.0 [2]
	(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-Amino-2-[[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-3-phenylpropanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-cyclohexylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	IC50	2600.0 [1], 2630.27 [2]
	(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-Amino-2-[[(2S)-2-(methylamino)-3-phenylpropanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	IC50	144000.0 [1], 1000000.0 [2]
	2-[3-[(3S,6S,9R,12S,15R,18S)-6-Benzyl-15-(cyclohexylmethyl)-3,12-bis(1H-indol-3-ylmethyl)-7-methyl-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,16-hexazabicyclo[16.3.0]henicosan-9-yl]propyl]guanidine	IC50	2951.21 [1], 3000.0 [2]
	(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-cyclohexylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	IC50	5888.44 [1], 5900.0 [2]
	(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-3-cyclohexylpropanoyl]amino]-3-(9H-fluoren-9-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	IC50	114815.36 [1], 116000.0 [2]
	2-[3-[(3S,6S,9R,12S,15R,18S)-6-Benzyl-15-(cyclohexylmethyl)-3,12-bis(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,16-hexazabicyclo[16.3.0]henicosan-9-yl]propyl]guanidine	IC50	42657.95 [1], 43000.0 [2]
	(2S)-2-Acetamido-N-[(3S,9R,12S,15R,18S)-15-(cyclohexylmethyl)-9-[3-(diaminomethylideneamino)propyl]-12-(1H-indol-3-ylmethyl)-2,8,11,14,17-pentaoxo-1,7,10,13,16-pentazabicyclo[16.3.0]henicosan-3-yl]-3-phenylpropanamide	IC50	12.0 [1], 280.0 [2]
	(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-Amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]hexanoyl]amino]-3-phenylpropanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-cyclohexylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	IC50	4570.88 [1], 4600.0 [2]
	(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-Amino-2-[[(2S)-2-aminopropanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-cyclohexylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	IC50	1000000.0 [1]
	(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-cyclohexylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	IC50	9000.0 [1], 9120.11 [2]
	(2S)-N-[(2R)-1-[[(2S)-1-[[(2R)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-cyclohexyl-1-oxopropan-2-yl]-1-[(2S)-6-amino-2-[[(2S)-2-(methylamino)-3-phenylpropanoyl]amino]hexanoyl]pyrrolidine-2-carboxamide	IC50	500.0 [1], 14000.0 [2]
	(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-Amino-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-cyclohexylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	IC50	1949.84 [1], 2000.0 [2]
	(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-cyclohexylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	IC50	3548.13 [1], 3600.0 [2]
	(2S)-2-Acetamido-N-[(3S,10S,13S,16R,19S)-16-(cyclohexylmethyl)-10-[3-(diaminomethylideneamino)propyl]-13-(1H-indol-3-ylmethyl)-2,9,12,15,18-pentaoxo-1,8,11,14,17-pentazabicyclo[17.3.0]docosan-3-yl]-3-phenylpropanamide	IC50	90.0 [1], 3200.0 [2]
	(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[(2R)-2-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-2-aminoacetyl]pyrrolidine-2-carbonyl]amino]-3-cyclohexylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	IC50	3000.0 [1], 3019.95 [2]
	(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-Amino-2-[[(2S)-2-[[2-[[2-[[2-[[2-[5-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]hexanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]hexanoyl]amino]pentanoylamino]acetyl]amino]acetyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-cyclohexylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-carbamimidamidopentanoic acid	IC50	173.78 [1], 200.0 [2]
	(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-Amino-2-[[(2S)-2-[5-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]hexanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]hexanoyl]amino]pentanoylamino]-3-phenylpropanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-cyclohexylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	IC50	1200.0 [1], 1230.27 [2]
	N-(2-Acetylphenyl)-N,4-dimethylbenzenesulfonamide	IC50	60000.0 [1]
	N-(2-Benzoyl-4-bromophenyl)-N,4-dimethylbenzenesulfonamide	IC50	14600.0 [1], 60000.0 [2]
	N-(2-Benzoyl-4-chlorophenyl)-N,4-dimethylbenzenesulfonamide	IC50	8700.0 [1], 60000.0 [2]
	N-(2-(Indoline-1-carbonyl)phenyl)-N,4-dimethylbenzenesulfonamide	IC50	38300.0 [1], 44500.0 [2]
	2-(2,6-Diethylphenyl)-N-ethyl-4-methoxy-N-naphthalen-1-yl-5,6,7,8-tetrahydroquinolin-5-amine	IC50	10000.0 [1]
	2-(2,6-Diethylphenyl)-N-ethyl-4-methoxy-N-naphthalen-1-yl-5,6,7,8-tetrahydroquinolin-5-amine	Ki	8.9 [1]
	N-Ethyl-2-(2-fluorophenyl)-4-methoxy-N-naphthalen-1-yl-5,6,7,8-tetrahydroquinolin-5-amine	IC50	4600.0 [1]
	N-Ethyl-2-(2-fluorophenyl)-4-methoxy-N-naphthalen-1-yl-5,6,7,8-tetrahydroquinolin-5-amine	Ki	3700.0 [1]
	N-Ethyl-4-methoxy-N,2-dinaphthalen-1-yl-5,6,7,8-tetrahydroquinolin-5-amine	IC50	5900.0 [1]
	N-Ethyl-4-methoxy-N,2-dinaphthalen-1-yl-5,6,7,8-tetrahydroquinolin-5-amine	Ki	370.0 [1]
	2-(2-(2-(2,6-Diethylphenyl)-4-methoxy-5,6,7,8-tetrahydroquinolin-5-ylamino)phenyl)ethanol	IC50	30.0 [1]
	2-(2-(2-(2,6-Diethylphenyl)-4-methoxy-5,6,7,8-tetrahydroquinolin-5-ylamino)phenyl)ethanol	Ki	21.0 [1]
	(5-Chloro-2-(2-(2,6-diethylphenyl)-4-methoxy-5,6,7,8-tetrahydroquinolin-5-ylamino)phenyl)methanol	IC50	71.0 [1]
	(5-Chloro-2-(2-(2,6-diethylphenyl)-4-methoxy-5,6,7,8-tetrahydroquinolin-5-ylamino)phenyl)methanol	Ki	13.0 [1]
	CID 25191897	IC50	140.0 [1]
	CID 25191897	Ki	10.0 [1]
	2-[[2-(2,6-Diethylphenyl)-4-methoxy-5,6,7,8-tetrahydroquinolin-5-yl]-naphthalen-1-ylamino]ethanol	IC50	190.0 [1]
	2-[[2-(2,6-Diethylphenyl)-4-methoxy-5,6,7,8-tetrahydroquinolin-5-yl]-naphthalen-1-ylamino]ethanol	Ki	180.0 [1]
	2-(2,6-Diethylphenyl)-4-methoxy-N-methyl-N-naphthalen-1-yl-5,6,7,8-tetrahydroquinolin-5-amine	IC50	170.0 [1]
	2-(2,6-Diethylphenyl)-4-methoxy-N-methyl-N-naphthalen-1-yl-5,6,7,8-tetrahydroquinolin-5-amine	Ki	7.3 [1]
	2-(2,6-Diethylphenyl)-4-methoxy-5-[8-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-5,6,7,8-tetrahydroquinoline	IC50	270.0 [1]
	2-(2,6-Diethylphenyl)-4-methoxy-5-[8-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-5,6,7,8-tetrahydroquinoline	Ki	9.7 [1]
	2-(2,6-Diethylphenyl)-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-methoxy-5,6,7,8-tetrahydroquinoline	IC50	1100.0 [1]
	2-(2,6-Diethylphenyl)-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-methoxy-5,6,7,8-tetrahydroquinoline	Ki	35.0 [1]
	N-Ethyl-2-(2-ethylphenyl)-4-methoxy-N-naphthalen-1-yl-5,6,7,8-tetrahydroquinolin-5-amine	IC50	650.0 [1]
	N-Ethyl-2-(2-ethylphenyl)-4-methoxy-N-naphthalen-1-yl-5,6,7,8-tetrahydroquinolin-5-amine	Ki	86.0 [1]
	2-(2,6-Dimethoxyphenyl)-N-ethyl-4-methoxy-N-naphthalen-1-yl-5,6,7,8-tetrahydroquinolin-5-amine	IC50	1800.0 [1]
	2-(2,6-Dimethoxyphenyl)-N-ethyl-4-methoxy-N-naphthalen-1-yl-5,6,7,8-tetrahydroquinolin-5-amine	Ki	1200.0 [1]
	4-Chloro-2-(2,6-diethylphenyl)-N-ethyl-N-naphthalen-1-yl-5,6,7,8-tetrahydroquinolin-5-amine	IC50	2000.0 [1]
	4-Chloro-2-(2,6-diethylphenyl)-N-ethyl-N-naphthalen-1-yl-5,6,7,8-tetrahydroquinolin-5-amine	Ki	180.0 [1]
	N-[1-(4-Chlorophenyl)-3-(dimethylamino)propan-2-yl]-N-(1,4-dioxaspiro[4.5]decan-8-yl)naphthalene-1-carboxamide	IC50	13.0 [1], 22.0 [2]
	(2S)-2-Amino-N-[(3S,9R,12S,15R,18S)-15-(cyclohexylmethyl)-9-[2-(diaminomethylideneamino)ethyl]-12-(1H-indol-3-ylmethyl)-2,8,11,14,17-pentaoxo-1,7,10,13,16-pentazabicyclo[16.3.0]henicosan-3-yl]-3-phenylpropanamide	IC50	3090.3 [1], 3100.0 [2]
	(2S)-2-Acetamido-N-[(3S,8R,11S,14R,17S)-14-(cyclohexylmethyl)-8-[2-(diaminomethylideneamino)ethyl]-11-(1H-indol-3-ylmethyl)-2,7,10,13,16-pentaoxo-1,6,9,12,15-pentazabicyclo[15.3.0]icosan-3-yl]-3-phenylpropanamide	IC50	16982.44 [1], 17000.0 [2]
	(2S)-2-Acetamido-N-[(3S,10R,13S,16R,19S)-16-(cyclohexylmethyl)-10-[2-(diaminomethylideneamino)ethyl]-13-(1H-indol-3-ylmethyl)-2,9,12,15,18-pentaoxo-1,8,11,14,17-pentazabicyclo[17.3.0]docosan-3-yl]-3-phenylpropanamide	IC50	3200.0 [1], 3235.94 [2]
	(2S)-2-Acetamido-N-[(3S,9R,12S,15R,18S)-15-(cyclohexylmethyl)-9-[2-(diaminomethylideneamino)ethyl]-12-(1H-indol-3-ylmethyl)-2,8,11,14,17-pentaoxo-1,7,10,13,16-pentazabicyclo[16.3.0]henicosan-3-yl]-3-phenylpropanamide	IC50	16000.0 [1], 25118.86 [2]
	(2S)-2-Amino-N-[(3S,7R,10S,13R,16S)-13-(cyclohexylmethyl)-7-[2-(diaminomethylideneamino)ethyl]-10-(1H-indol-3-ylmethyl)-2,6,9,12,15-pentaoxo-1,5,8,11,14-pentazabicyclo[14.3.0]nonadecan-3-yl]-3-phenylpropanamide	IC50	40738.03 [1], 41000.0 [2]
	(2S)-2-Amino-N-[(3S,9S,12S,15R,18S)-15-(cyclohexylmethyl)-9-[2-(diaminomethylideneamino)ethyl]-12-(1H-indol-3-ylmethyl)-2,8,11,14,17-pentaoxo-1,7,10,13,16-pentazabicyclo[16.3.0]henicosan-3-yl]-3-phenylpropanamide	IC50	56.23 [1], 60.0 [2]
	(2S)-2-Acetamido-N-[(3S,7R,10S,13R,16S)-13-(cyclohexylmethyl)-7-[2-(diaminomethylideneamino)ethyl]-10-(1H-indol-3-ylmethyl)-2,6,9,12,15-pentaoxo-1,5,8,11,14-pentazabicyclo[14.3.0]nonadecan-3-yl]-3-phenylpropanamide	IC50	9500.0 [1], 9549.93 [2]
	(2S)-2-Acetamido-N-[(3S,9S,12S,15R,18S)-15-(cyclohexylmethyl)-9-[2-(diaminomethylideneamino)ethyl]-12-(1H-indol-3-ylmethyl)-2,8,11,14,17-pentaoxo-1,7,10,13,16-pentazabicyclo[16.3.0]henicosan-3-yl]-3-phenylpropanamide	IC50	269.15 [1], 300.0 [2]
	(2S)-2-Amino-N-[(3S,7S,10S,13R,16S)-13-(cyclohexylmethyl)-7-[2-(diaminomethylideneamino)ethyl]-10-(1H-indol-3-ylmethyl)-2,6,9,12,15-pentaoxo-1,5,8,11,14-pentazabicyclo[14.3.0]nonadecan-3-yl]-3-phenylpropanamide	IC50	10000.0 [1], 10471.29 [2]
	(2S)-2-Amino-N-[(3S,8S,11S,14R,17S)-14-(cyclohexylmethyl)-8-[2-(diaminomethylideneamino)ethyl]-11-(1H-indol-3-ylmethyl)-2,7,10,13,16-pentaoxo-1,6,9,12,15-pentazabicyclo[15.3.0]icosan-3-yl]-3-phenylpropanamide	IC50	300.0 [1], 309.03 [2]
	(2S)-2-Amino-N-[(3S,8R,11S,14R,17S)-14-(cyclohexylmethyl)-8-[2-(diaminomethylideneamino)ethyl]-11-(1H-indol-3-ylmethyl)-2,7,10,13,16-pentaoxo-1,6,9,12,15-pentazabicyclo[15.3.0]icosan-3-yl]-3-phenylpropanamide	IC50	3800.0 [1], 3801.89 [2]
	(2S)-2-Amino-N-[(3S,10S,13S,16R,19S)-16-(cyclohexylmethyl)-10-[2-(diaminomethylideneamino)ethyl]-13-(1H-indol-3-ylmethyl)-2,9,12,15,18-pentaoxo-1,8,11,14,17-pentazabicyclo[17.3.0]docosan-3-yl]-3-phenylpropanamide	IC50	300.0 [1], 331.13 [2]
	(2S)-2-Amino-N-[(3S,10R,13S,16R,19S)-16-(cyclohexylmethyl)-10-[2-(diaminomethylideneamino)ethyl]-13-(1H-indol-3-ylmethyl)-2,9,12,15,18-pentaoxo-1,8,11,14,17-pentazabicyclo[17.3.0]docosan-3-yl]-3-phenylpropanamide	IC50	8100.0 [1], 8128.31 [2]
	(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-Amino-2-[[(2S)-2-(methylamino)-3-phenylpropanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-cyclohexylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	IC50	1800.0 [1], 14000.0 [2]
	N-Ethyl-4-methoxy-N-naphthalen-1-yl-2-phenyl-5,6,7,8-tetrahydroquinolin-5-amine	IC50	10000.0 [1]
	N-Ethyl-4-methoxy-N-naphthalen-1-yl-2-phenyl-5,6,7,8-tetrahydroquinolin-5-amine	Ki	8300.0 [1]
	Ethyl 3-(4-chlorophenyl)-2-[1,4-dioxaspiro[4.5]decan-8-yl(naphthalene-1-carbonyl)amino]propanoate	IC50	3.0 [1], 32.0 [2]
	Methyl 2-[1-benzothiophene-3-carbonyl(1,4-dioxaspiro[4.5]decan-8-yl)amino]-3-(4-chlorophenyl)propanoate	IC50	15.0 [1], 172.0 [2]
	N-[2-(4-Chlorophenyl)-1-(5-methyl-1,2,4-oxadiazol-3-yl)ethyl]-N-(1,4-dioxaspiro[4.5]decan-8-yl)-2-ethylbenzamide	IC50	8.0 [1], 40.0 [2]
	N-[1-(4-Chlorophenyl)-3-methoxypropan-2-yl]-N-(1,4-dioxaspiro[4.5]decan-8-yl)-1-benzothiophene-3-carboxamide	IC50	12.0 [1], 27.0 [2]
	N-[1-(4-Chlorophenyl)-3-(dimethylamino)propan-2-yl]-N-(1,4-dioxaspiro[4.5]decan-8-yl)-2-ethylbenzamide	IC50	25.0 [1], 27.0 [2]
	5-[(4-Chlorophenyl)methyl]-1-(1,4-dioxaspiro[4.5]decan-8-yl)-2-naphthalen-1-ylimidazole	IC50	90.0 [1], 877.0 [2]
	2-(1-Benzothiophen-3-yl)-5-(cyclohexylmethyl)-1-(1,4-dioxaspiro[4.5]decan-8-yl)imidazole	IC50	47.0 [1], 850.0 [2]
	cis-N-(4-Chlorophenethyl)-N-(4-hydroxycyclohexyl)benzo[b]thiophene-3-carboxamide	IC50	70.0 [1], 200.0 [2]
	N-[2-(4-Chlorophenyl)ethyl]-N-(1-oxaspiro[4.5]decan-8-yl)-1-benzothiophene-3-carboxamide	IC50	5.0 [1], 200.0 [2]
	1,4-Ditosyl-1,2,3,4-tetrahydroquinoxaline	IC50	60000.0 [1]
	5,12-Bis-(4-methylphenyl)sulfonyl-6,11-dihydrobenzo[c][1,6]benzodiazocine	IC50	60000.0 [1]
	4-Methyl-N-[3-(N-(4-methylphenyl)sulfonylanilino)propyl]-N-phenylbenzenesulfonamide	IC50	60000.0 [1]
	2-[3-[(4R)-1-[(2R)-3-Cyclohexyl-1-oxo-1-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylpropan-2-yl]-2,5-dioxoimidazolidin-4-yl]propyl]guanidine	IC50	25.0 [1], 300.0 [2]
	2-[3-[(4R)-1-[(2R)-3-Cyclohexyl-1-[4-(2,4-dimethylphenyl)piperazin-1-yl]-1-oxopropan-2-yl]-2,5-dioxoimidazolidin-4-yl]propyl]guanidine	IC50	60.0 [1], 300.0 [2]
	2-[3-[(4R)-1-[(2R)-3-Cyclohexyl-1-[4-(2,6-dimethylphenyl)piperazin-1-yl]-1-oxopropan-2-yl]-2,5-dioxoimidazolidin-4-yl]propyl]guanidine	IC50	40.0 [1], 220.0 [2]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ C5a anaphylatoxin chemotactic receptor Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/c5a-anaphylatoxin-chemotactic-receptor-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 10). Quest Database™ C5a anaphylatoxin chemotactic receptor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/c5a-anaphylatoxin-chemotactic-receptor-inhibitors-ic50-ki.
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