 | Olcegepant | IC50 | 0.1 [1] |
| Olcegepant | Ki | 0.01 [1] |
 | 4-(2-Oxo-3H-benzimidazol-1-yl)-N-[(3R)-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepin-3-yl]piperidine-1-carboxamide | IC50 | 1580.0 [1] |
| 4-(2-Oxo-3H-benzimidazol-1-yl)-N-[(3R)-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepin-3-yl]piperidine-1-carboxamide | Ki | 2370.0 [1] |
 | Fvptdvgpfaf | Ki | 0.02 [1], 14.0 [2] |
 | Fvptdvgafaf | Ki | 13.6 [1], 76.8 [2] |
 | N-[(3R)-1-Methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | IC50 | 3640.0 [1] |
| N-[(3R)-1-Methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | Ki | 2200.0 [1] |
 | N-[(3R)-1-(Cyclopropylmethyl)-2-oxoazepan-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | IC50 | 2400.0 [1] |
| N-[(3R)-1-(Cyclopropylmethyl)-2-oxoazepan-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | Ki | 7800.0 [1] |
 | N-[(3R,6S)-1-(Cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl]-4-(2-oxo-5-phenyl-1H-imidazol-3-yl)piperidine-1-carboxamide | IC50 | 4.0 [1] |
| N-[(3R,6S)-1-(Cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl]-4-(2-oxo-5-phenyl-1H-imidazol-3-yl)piperidine-1-carboxamide | Ki | 2.0 [1] |
 | 4-(2-Oxo-1,4-dihydroquinazolin-3-yl)-N-(2-oxo-5-phenyl-1-propan-2-yl-3H-1,4-benzodiazepin-3-yl)piperidine-1-carboxamide | IC50 | 1810.0 [1] |
| 4-(2-Oxo-1,4-dihydroquinazolin-3-yl)-N-(2-oxo-5-phenyl-1-propan-2-yl-3H-1,4-benzodiazepin-3-yl)piperidine-1-carboxamide | Ki | 1060.0 [1] |
 | N-[(3S,6R)-1-(Cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | IC50 | 6626.0 [1] |
| N-[(3S,6R)-1-(Cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | Ki | 5828.0 [1] |
 | N-[(3R,7R)-1-(Cyclopropylmethyl)-2-oxo-7-phenylazepan-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | IC50 | 408.0 [1] |
| N-[(3R,7R)-1-(Cyclopropylmethyl)-2-oxo-7-phenylazepan-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | Ki | 689.0 [1] |
 | N-[(3R,6S)-1-(Cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | IC50 | 36.0 [1] |
| N-[(3R,6S)-1-(Cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | Ki | 25.0 [1] |
 | N-[(3S)-1-Methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | IC50 | 4450.0 [1] |
| N-[(3S)-1-Methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | Ki | 8400.0 [1] |
 | N-[(3R)-1-Ethyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | IC50 | 990.0 [1] |
| N-[(3R)-1-Ethyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | Ki | 897.0 [1] |
 | 4-(2-Oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)-N-[(3R)-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepin-3-yl]piperidine-1-carboxamide | IC50 | 43.0 [1] |
| 4-(2-Oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)-N-[(3R)-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepin-3-yl]piperidine-1-carboxamide | Ki | 61.0 [1] |
 | N-[(3R,6S)-1-(Cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl]-4-(5-oxo-3-phenyl-4H-1,2,4-triazol-1-yl)piperidine-1-carboxamide | IC50 | 45.0 [1] |
| N-[(3R,6S)-1-(Cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl]-4-(5-oxo-3-phenyl-4H-1,2,4-triazol-1-yl)piperidine-1-carboxamide | Ki | 29.0 [1] |
 | N-[1-(Cyclopropylmethyl)-2-oxo-5-phenylazepan-3-yl]-4-(5-oxo-3-phenyl-4H-1,2,4-triazol-1-yl)piperidine-1-carboxamide | IC50 | 3821.0 [1] |
| N-[1-(Cyclopropylmethyl)-2-oxo-5-phenylazepan-3-yl]-4-(5-oxo-3-phenyl-4H-1,2,4-triazol-1-yl)piperidine-1-carboxamide | Ki | 544.0 [1] |
 | N-[1-(Cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | IC50 | 778.0 [1] |
| N-[1-(Cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | Ki | 695.0 [1] |
 | N-[(2R)-3-(3,5-Dibromo-4-hydroxyphenyl)-1-oxo-1-(4-phenylpiperazin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide | IC50 | 75.0 [1] |
| N-[(2R)-3-(3,5-Dibromo-4-hydroxyphenyl)-1-oxo-1-(4-phenylpiperazin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide | Ki | 83.0 [1] |
 | 4-(2-Oxo-1,4-dihydroquinazolin-3-yl)-N-[(3R)-2-oxo-5-phenyl-1-propan-2-yl-3H-1,4-benzodiazepin-3-yl]piperidine-1-carboxamide | IC50 | 65.0 [1] |
| 4-(2-Oxo-1,4-dihydroquinazolin-3-yl)-N-[(3R)-2-oxo-5-phenyl-1-propan-2-yl-3H-1,4-benzodiazepin-3-yl]piperidine-1-carboxamide | Ki | 55.0 [1] |
 | 4-(2-Oxo-1,4-dihydroquinazolin-3-yl)-N-(2-oxo-1-propan-2-yl-4,5-dihydro-3H-1-benzazepin-3-yl)piperidine-1-carboxamide | IC50 | 3100.0 [1] |
| 4-(2-Oxo-1,4-dihydroquinazolin-3-yl)-N-(2-oxo-1-propan-2-yl-4,5-dihydro-3H-1-benzazepin-3-yl)piperidine-1-carboxamide | Ki | 3700.0 [1] |
 | Tert-butyl 2-[2-oxo-3-[[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carbonyl]amino]-7-phenylazepan-1-yl]acetate | IC50 | 2118.0 [1] |
| Tert-butyl 2-[2-oxo-3-[[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carbonyl]amino]-7-phenylazepan-1-yl]acetate | Ki | 16950.0 [1] |
 | Tert-butyl 2-[(3S,7S)-2-oxo-3-[[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carbonyl]amino]-7-phenylazepan-1-yl]acetate | IC50 | 471.0 [1] |
| Tert-butyl 2-[(3S,7S)-2-oxo-3-[[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carbonyl]amino]-7-phenylazepan-1-yl]acetate | Ki | 10000.0 [1] |
 | N-[(3R,6S)-1-(Cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl]-4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidine-1-carboxamide | IC50 | 32.0 [1] |
| N-[(3R,6S)-1-(Cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl]-4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidine-1-carboxamide | Ki | 29.0 [1] |
 | N-[1-(Cyclopropylmethyl)-2-oxo-5-phenylazepan-3-yl]-4-(2-oxo-5-phenyl-1H-imidazol-3-yl)piperidine-1-carboxamide | IC50 | 133.0 [1] |
| N-[1-(Cyclopropylmethyl)-2-oxo-5-phenylazepan-3-yl]-4-(2-oxo-5-phenyl-1H-imidazol-3-yl)piperidine-1-carboxamide | Ki | 17.0 [1] |
 | (3S)-2-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(3S)-2-[2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-3-carboxypropanoyl]amino]-3-methylbutanoyl]amino]acetyl]-3,4-dihydro-1H-isoquinoline-3-carbonyl]amino]-3-phenylpropanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid | Ki | 1.8 [1], 70.5 [2] |
 | MK-3207 | Ki | 0.02 [1] |
 | Ubrogepant | Ki | 0.07 [1] |
 | 2-[(8R)-8-(3,5-Difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]acetamide | Ki | 0.05 [1] |
 | 4-(2-Oxo-1,4-dihydroquinazolin-3-yl)-N-[(3R)-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepin-3-yl]piperidine-1-carboxamide | Ki | 44.0 [1] |
 | (3S)-3-[[(2S,3R)-2-[[2-[[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-2-methylpropanoyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid | Ki | 0.0 [1] |
 | 2-[(8R)-8-(3,5-Difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide | Ki | 0.04 [1] |
 | Tert-butyl 2-[(3R,7R)-2-oxo-3-[[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carbonyl]amino]-7-phenylazepan-1-yl]acetate | Ki | 934.0 [1] |
 | N-[(3S)-1-Benzyl-2-oxoazepan-3-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide | Ki | 11100.0 [1] |
 | (R)-N-(1-Benzyl-2-oxoazepan-3-yl)-4-(2-oxo-1,2-dihydroquinazolin-3(4H)-yl)piperidine-1-carboxamide | Ki | 1800.0 [1] |
 | (3S)-3-[[(2S,3R)-2-[[(3S)-2-[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]-3,4-dihydro-1H-isoquinoline-3-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid | Ki | 0.02 [1] |
 | N-(1-Methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl)-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide | Ki | 13000.0 [1] |
 | (3S)-3-[[(2S,3R)-2-[[(1S,2S,3S)-2-[[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-3-methoxycarbonylcyclopropanecarbonyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid | Ki | 10000.0 [1] |
 | (3S)-3-[[(2S,3R)-2-[[(1R,2R,3R)-2-[[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-3-methoxycarbonylcyclopropanecarbonyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid | Ki | 0.7 [1] |
 | (3S)-3-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[[(1R,2R,3R)-2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]-3-methoxycarbonylcyclopropyl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid | Ki | 10000.0 [1] |
 | Fvatdvgpfaf | Ki | 8.4 [1] |
 | (2S)-2-[[(2S)-2-[[(2S)-2-[[(1S,2S,3S)-2-[[2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-oxobutanoyl]amino]-3-methylbutanoyl]amino]acetyl]amino]-3-methoxycarbonylcyclopropanecarbonyl]amino]-3-phenylpropanoyl]amino]propanoyl]amino]-3-phenylpropanoic acid | Ki | 10000.0 [1] |
 | (2S)-2-[[(2S)-2-[[(2S)-2-[[(1R,2R,3R)-2-[[2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-oxobutanoyl]amino]-3-methylbutanoyl]amino]acetyl]amino]-3-methoxycarbonylcyclopropanecarbonyl]amino]-3-phenylpropanoyl]amino]propanoyl]amino]-3-phenylpropanoic acid | Ki | 10000.0 [1] |
 | (3S)-3-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[[(1S,2S,3S)-2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]-3-methoxycarbonylcyclopropyl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid | Ki | 10000.0 [1] |
 | 1-(2',5'-Dioxospiro[7,8-dihydro-5H-naphthalene-6,4'-imidazolidine]-2-yl)-3-[(3R)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]urea | Ki | 4250.0 [1] |
 | N-[(1R)-1-(3,5-Difluorophenyl)ethyl]-3,5-dimethyl-N-[(E)-3-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]prop-2-enyl]-1,2-oxazole-4-carboxamide | Ki | 2.39 [1] |
 | N-[(1R)-1-(3,5-Difluorophenyl)ethyl]-N-[(E)-3-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]prop-2-enyl]-1-(trifluoromethyl)cyclopropane-1-carboxamide | Ki | 0.05 [1] |
 | N-[(1R)-1-(3,5-Difluorophenyl)ethyl]-2,5-dimethyl-N-[(E)-3-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]prop-2-enyl]pyrazole-3-carboxamide | Ki | 0.45 [1] |
 | N-[(1R)-1-(3-Fluoro-4-methylphenyl)ethyl]-2,2-dimethyl-N-[(E)-3-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]prop-2-enyl]propanamide | Ki | 0.13 [1] |
 | 2-[(8R)-8-(3,5-Difluorophenyl)-8-ethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]acetamide | Ki | 0.25 [1] |
 | 2-[(8R)-8-(4-Chloro-3,5-difluorophenyl)-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]acetamide | Ki | 0.01 [1] |
 | 2-[(8R)-8-(4-Chloro-3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]acetamide | Ki | 0.02 [1] |
 | 2-[(8R)-8-(3,5-Difluorophenyl)-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]acetamide | Ki | 0.03 [1] |
 | N-[(1R)-1-(3,5-Difluorophenyl)ethyl]-2,2-dimethyl-N-[(E)-3-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]prop-2-enyl]propanamide | Ki | 0.04 [1] |
 | 2,2-Dimethyl-N-[(E)-3-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]prop-2-enyl]-N-[(1R)-1-phenylethyl]propanamide | Ki | 0.35 [1] |
 | N-[(1R)-2,3-Dihydro-1H-inden-1-yl]-2,2-dimethyl-N-[(E)-3-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]prop-2-enyl]propanamide | Ki | 0.2 [1] |
 | N-[(1R)-1-(3,5-Difluorophenyl)ethyl]-2-methyl-N-[(E)-3-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]prop-2-enyl]propanamide | Ki | 1.27 [1] |
 | N-[(1R)-1-(3,5-Difluorophenyl)ethyl]-N-[(E)-3-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]prop-2-enyl]oxane-4-carboxamide | Ki | 0.09 [1] |
 | (2S)-N-[(1R)-1-(3,5-Difluorophenyl)ethyl]-1-methyl-N-[(E)-3-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]prop-2-enyl]pyrrolidine-2-carboxamide | Ki | 3.38 [1] |
 | 2,2-Dimethyl-N-[(E)-3-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]prop-2-enyl]-N-[(1R)-1-phenylethyl]propanamide | Ki | 0.22 [1] |
 | N-[(1R)-2,3-Dihydro-1H-inden-1-yl]-2,2-dimethyl-N-[(E)-3-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]prop-2-enyl]propanamide | Ki | 0.08 [1] |
 | N-[(3,5-Difluorophenyl)methyl]-2,2-dimethyl-N-[(E)-3-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]prop-2-enyl]propanamide | Ki | 0.93 [1] |
 | N-Cycloheptyl-2,2-dimethyl-N-[(E)-3-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]prop-2-enyl]propanamide | Ki | 0.89 [1] |
 | N-[(1R)-1-(4-Chlorophenyl)ethyl]-2,2-dimethyl-N-[(E)-3-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]prop-2-enyl]propanamide | Ki | 0.31 [1] |
 | N-[(1R)-2,3-Dihydro-1H-inden-1-yl]-2,2-dimethyl-N-[3-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]prop-2-ynyl]propanamide | Ki | 0.2 [1] |
 | 2,2-Dimethyl-N-[3-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]prop-2-ynyl]-N-[(1R)-1-phenylethyl]propanamide | Ki | 0.82 [1] |
 | N-[(1R)-2,3-Dihydro-1H-inden-1-yl]-2,2-dimethyl-N-[3-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]prop-2-ynyl]propanamide | Ki | 0.05 [1] |
 | 2,2-Dimethyl-N-[3-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]prop-2-ynyl]-N-[(1R)-1-phenylethyl]propanamide | Ki | 0.13 [1] |
 | N-[(1R)-2,3-Dihydro-1H-inden-1-yl]-2,2-dimethyl-N-[3-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]propyl]propanamide | Ki | 2.06 [1] |
 | 2,2-Dimethyl-N-[3-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]propyl]-N-[(1R)-1-phenylethyl]propanamide | Ki | 7.6 [1] |
 | N-[(1R)-1-(3,5-Difluorophenyl)ethyl]-2,2-dimethyl-N-[3-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]propyl]propanamide | Ki | 0.22 [1] |
 | N-[(1R)-2,3-Dihydro-1H-inden-1-yl]-2,2-dimethyl-N-[3-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]propyl]propanamide | Ki | 0.61 [1] |
 | 2,2-Dimethyl-N-[3-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]propyl]-N-[(1R)-1-phenylethyl]propanamide | Ki | 1.35 [1] |
 | N-[(1R)-1-(3,5-Difluorophenyl)ethyl]-2,2-dimethyl-N-[(E)-3-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]prop-2-enyl]propanamide | Ki | 0.16 [1] |
 | (3S)-3-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]piperidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid | Ki | 10000.0 [1] |
 | (3S)-3-[[(2S,3R)-2-[[(2S,4R)-1-[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]-4-hydroxypyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid | Ki | 0.01 [1] |
 | N-[(1R)-1-(3,5-Difluorophenyl)ethyl]-1-methyl-N-[(E)-3-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]prop-2-enyl]imidazole-2-carboxamide | Ki | 0.16 [1] |
 | N-[(1R)-1-(3,5-Difluorophenyl)ethyl]-3-methyl-N-[(E)-3-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]prop-2-enyl]thiophene-2-carboxamide | Ki | 0.13 [1] |
 | N-[(3R,6S)-6-(2,3-Difluorophenyl)-1-methyl-2-oxoazepan-3-yl]-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-carboxamide | Ki | 7.4 [1] |
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