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Carboxypeptidase A1 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
(2S)-2-[[(2S,3R)-3-Methyl-2-sulfanylpentanoyl]amino]-3-(4-phenylphenyl)propanoic acidKi11000.0 [1]
2-Benzylsuccinic acidIC50400.0 [1]
Anabaenopeptin FIC501100.0 [1]
Anabaenopeptin BIC503900.0 [1]
alpha-Benzyl-1H-imidazole-4-acetic acidIC501700.0 [1]
(R)-2-Benzylsuccinic acidKi450.0 [1]
3-Pyridinepropanoic acid, 6-amino-alpha-1H-imidazol-5-yl-IC5050000.0 [1]
3-(6-Aminopyridin-3-yl)-2-[1-(3-methylbutyl)imidazol-4-yl]propanoic acidIC502200.0 [1]
2-Benzyl-5,5,5-trifluoro-4-oxopentanoic acidKi200.0 [1]
CID 44377139Ki310.0 [1]
CID 44452012Ki790.0 [1]
(2S)-6-Amino-2-[[(3S,6S,9S,12S,15R)-3-benzyl-9-[2-(4-hydroxyphenyl)ethyl]-6,7-dimethyl-2,5,8,11,14-pentaoxo-12-propan-2-yl-1,4,7,10,13-pentazacyclononadec-15-yl]carbamoylamino]hexanoic acidIC50100000.0 [1]
(2R)-3-(4-Iodophenyl)-2-[(2S)-thiiran-2-yl]propanoic acidKi289000.0 [1]
(2R)-2-[(2R)-Thiiran-2-yl]pentanoic acidKi294000.0 [1]
(2R)-4-Methyl-2-[(2R)-thiiran-2-yl]pentanoic acidKi56000.0 [1]
(2S)-3-(4-Iodophenyl)-2-[(2R)-oxiran-2-yl]propanoic acidKi413000.0 [1]
(2S)-3-(4-Fluorophenyl)-2-[(2R)-oxiran-2-yl]propanoic acidKi238000.0 [1]
(2R)-3-(4-Fluorophenyl)-2-[(2S)-thiiran-2-yl]propanoic acidKi60400.0 [1]
2-Benzyl-4-oxopentanoic acidKi207000.0 [1]
(2R)-2-Benzyl-3-nitropropanoic acidKi150.0 [1]
2-Benzyl-5-bromo-4-oxopentanoic acidKi15000.0 [1]
(2S)-2-[[(2S)-3-Methyl-2-sulfanylbutanoyl]amino]-3-(4-phenylphenyl)propanoic acidKi17000.0 [1]
(2S)-2-[[(2S)-4,4-Dimethyl-2-sulfanylpentanoyl]amino]-3-(4-phenylphenyl)propanoic acidKi22000.0 [1]
2-(4,4-Diaminobut-3-enylsulfanylmethyl)-3-sulfanylpropanoic acidIC5050000.0 [1]
3-(Benzoyl-hydroxy-amino)-2-benzyl-propionic acidKi6500.0 [1]
2-Benzyl-3-(hydroxy-propionyl-amino)-propionic acidKi5820.0 [1]
(S)-2-Benzyl-3-(formyl-hydroxy-amino)-propionic acidKi4950.0 [1]
2-Benzyl-3-[hydroxy-(3-phenyl-propionyl)-amino]-propionic acidKi1200.0 [1]
2-Benzyl-3-[hydroxy-(4-phenyl-butyryl)-amino]-propionic acidKi1160.0 [1]
2-Benzyl-3-(formyl-hydroxy-amino)-propionic acidKi980.0 [1]
(R)-2-Benzyl-3-(formyl-hydroxy-amino)-propionic acidKi560.0 [1]
3-(Acetyl-hydroxy-amino)-2-benzyl-propionic acidKi5900.0 [1]
CPA inhibitorKi320.0 [1]
(S)-3-Biphenyl-4-yl-2-((S)-2-mercapto-3-phenyl-propionylamino)-propionic acidKi1200.0 [1]
2-[[(2S,3R)-3-Methyl-2-sulfanylpentanoyl]amino]acetic acidKi35000.0 [1]
(2S)-2-[[(2S,3R)-3-Methyl-2-sulfanylpentanoyl]amino]propanoic acidKi11000.0 [1]
(2S)-2-[[(2S,3R)-3-Methyl-2-sulfanylpentanoyl]amino]-3-phenylpropanoic acidKi530.0 [1]
(2S)-3-(4-Hydroxyphenyl)-2-[[(2S,3R)-3-methyl-2-sulfanylpentanoyl]amino]propanoic acidKi350.0 [1]
(2S)-2-[[(2S,3R)-3-Methyl-2-sulfanylpentanoyl]amino]-3-naphthalen-1-ylpropanoic acidKi3600.0 [1]
(2S)-2-[[(2S,3R)-3-Methyl-2-sulfanylpentanoyl]amino]-3-naphthalen-2-ylpropanoic acidKi7200.0 [1]
(2S)-2-[[(2S,3R)-3-Methyl-2-sulfanylpentanoyl]amino]-3-(2-phenylphenyl)propanoic acidKi9900.0 [1]
(2S)-2-[[(2S,3R)-3-Methyl-2-sulfanylpentanoyl]amino]-3-(3-phenylphenyl)propanoic acidKi5000.0 [1]
(2S)-2-[[(2S,3R)-3-Methyl-2-sulfanylpentanoyl]amino]-3-(2-phenoxyphenyl)propanoic acidKi2300.0 [1]
(2S)-2-[[(2S,3R)-3-Methyl-2-sulfanylpentanoyl]amino]-3-(3-phenoxyphenyl)propanoic acidKi14000.0 [1]
(2S)-2-[[(2S,3R)-3-Methyl-2-sulfanylpentanoyl]amino]-3-(4-phenoxyphenyl)propanoic acidKi8900.0 [1]
(2S)-2-[[(2S,3R)-3-Methyl-2-sulfanylpentanoyl]amino]-3-(2-phenylmethoxyphenyl)propanoic acidKi1600.0 [1]
(2S)-2-[[(2S,3R)-3-Methyl-2-sulfanylpentanoyl]amino]-3-(3-phenylmethoxyphenyl)propanoic acidKi5000.0 [1]
(2S)-2-[[(2S,3R)-3-Methyl-2-sulfanylpentanoyl]amino]-3-(4-phenylmethoxyphenyl)propanoic acidKi4600.0 [1]
(2S)-3-[4-[(4-Fluorophenyl)methoxy]phenyl]-2-[[(2S,3R)-3-methyl-2-sulfanylpentanoyl]amino]propanoic acidKi16000.0 [1]
(2S)-3-[4-[(2,4-Difluorophenyl)methoxy]phenyl]-2-[[(2S,3R)-3-methyl-2-sulfanylpentanoyl]amino]propanoic acidKi1900.0 [1]
(2S)-3-[4-[(3,4-Difluorophenyl)methoxy]phenyl]-2-[[(2S,3R)-3-methyl-2-sulfanylpentanoyl]amino]propanoic acidKi3300.0 [1]
(2S)-2-[[(2S,3R)-3-Methyl-2-sulfanylpentanoyl]amino]-3-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]propanoic acidKi4600.0 [1]
(2S)-3-[4-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]phenyl]-2-[[(2S,3R)-3-methyl-2-sulfanylpentanoyl]amino]propanoic acidKi11000.0 [1]
4-Methyl-2-(nitromethyl)pentanoic acidKi2080.0 [1]
(2S)-2-Benzyl-3-nitropropanoic acidKi68000.0 [1]
2-(Nitromethyl)pent-4-enoic acidKi62600.0 [1]
(2S)-2-[[(2S)-2-Cyclohexyl-2-sulfanylacetyl]amino]-3-(4-phenylphenyl)propanoic acidKi12000.0 [1]
(2S)-2-[[(2S)-2-Cyclobutyl-2-sulfanylacetyl]amino]-3-(4-phenylphenyl)propanoic acidKi12000.0 [1]
(2S)-2-[[(2S)-2-Cyclopentyl-2-sulfanylacetyl]amino]-3-(4-phenylphenyl)propanoic acidKi12000.0 [1]
(2S)-2-[[(2S,3S)-3-Methyl-2-sulfanylpentanoyl]amino]-3-(4-phenylphenyl)propanoic acidKi15000.0 [1]
(2S)-3-(4-Phenylphenyl)-2-[[(2S)-2-sulfanylhexanoyl]amino]propanoic acidKi8900.0 [1]
(2S)-2-[(2-Methyl-2-sulfanylpropanoyl)amino]-3-(4-phenylphenyl)propanoic acidKi50000.0 [1]
(2S)-3-(4-Phenylphenyl)-2-[[(2S)-2-sulfanylbutanoyl]amino]propanoic acidKi9300.0 [1]
(2S)-3-(4-Phenylphenyl)-2-[[(2S)-2-sulfanylpropanoyl]amino]propanoic acidKi14000.0 [1]
(2S)-3-(4-Phenylphenyl)-2-[(2-sulfanylacetyl)amino]propanoic acidKi1700.0 [1]
(2S)-3-(4-Phenylphenyl)-2-[[(2S)-4-phenyl-2-sulfanylbutanoyl]amino]propanoic acidKi5000.0 [1]
(2S)-2-[[(2S)-3-Naphthalen-2-yl-2-sulfanylpropanoyl]amino]-3-(4-phenylphenyl)propanoic acidKi32000.0 [1]
(2S)-2-[[(2S)-3-Cyclohexyl-2-sulfanylpropanoyl]amino]-3-(4-phenylphenyl)propanoic acidKi17000.0 [1]
(2S)-3-(4-Phenylphenyl)-2-[[(2S)-2-phenyl-2-sulfanylacetyl]amino]propanoic acidKi50000.0 [1]
(2S)-2-[[(2S)-4-Methyl-2-sulfanylpentanoyl]amino]-3-(4-phenylphenyl)propanoic acidKi11000.0 [1]
(R)-2-Benzyl-5-nitro-4-oxopentanoic acidKi160.0 [1]
2-Benzyl-5-nitro-4-oxo-pentanoic acidKi430.0 [1]
(S)-2-Benzyl-5-nitro-4-oxopentanoic acidKi31000.0 [1]
3-(6-Amino-pyridin-3-yl)-2-(1-isopropyl-1H-imidazol-4-yl)-propionic acidIC506400.0 [1]
Items per page: 1 - 10 of 74
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References

This online tool may be cited as follows

MLA

"Quest Database™ Carboxypeptidase A1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/carboxypeptidase-a1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 10). Quest Database™ Carboxypeptidase A1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/carboxypeptidase-a1-inhibitors-ic50-ki.
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