 | 4-[(E)-[5-(3-Chloroanilino)-7-cyclopropyliminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1300.0 [1], 2500.0 [2] |
 | N-[4-[[(3E)-7-Cyclopropylimino-3-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a]pyrimidin-5-yl]amino]cyclohexyl]acetamide | IC50 | 2500.0 [1] |
 | 4-[(E)-[5-[(4-Aminocyclohexyl)amino]-7-cyclopropyliminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 253.2 [1], 878.3 [2] |
 | 3-[4-[[(3E)-7-Cyclopropylimino-3-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a]pyrimidin-5-yl]amino]cyclohexyl]-1,1-dimethylurea | IC50 | 538.5 [1], 679.1 [2] |
 | 4-[(E)-[2-[(4-Aminocyclohexyl)amino]-4-cyclopropyliminopyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1], 2500.0 [2] |
 | 4-[(E)-[2-(3-Chlorophenoxy)-4-cyclopropyliminopyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1190.3 [1], 2500.0 [2] |
 | Methyl N-[4-[[(3E)-7-cyclopropylimino-3-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a]pyrimidin-5-yl]amino]cyclohexyl]carbamate | IC50 | 679.1 [1], 2500.0 [2] |
 | N-[4-[[(3E)-7-Cyclopropylimino-3-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a]pyrimidin-5-yl]amino]cyclohexyl]methanesulfonamide | IC50 | 476.0 [1], 2500.0 [2] |
 | 4-[(E)-[7-Amino-5-(3-chlorophenyl)iminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1177.9 [1] |
 | 4-[(E)-[7-Cyclopropylimino-5-(3-fluoroanilino)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2200.2 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-cyclobutyliminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 5-[(E)-[7-Cyclopropylimino-5-(2-fluoropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-4-hydroxy-3H-1,3-thiazol-2-one | IC50 | 217.6 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[(2-piperidin-1-ylphenyl)methylamino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[(3-fluorophenyl)methyl-methylamino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[2-[(3-Chloro-2-fluorophenyl)methylamino]-4-cyclopropyliminopyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[[(1R)-1-naphthalen-2-ylethyl]amino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[[(1S)-1-(3-methoxyphenyl)ethyl]amino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[1-[3-(trifluoromethyl)phenyl]ethylamino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[2-[(2-Chlorophenyl)methyl-methylamino]-4-cyclopropyliminopyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[2-[1-(1,3-Benzodioxol-5-yl)ethylamino]-4-cyclopropyliminopyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[1-(3,4-difluorophenyl)ethylamino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-(2,3-dihydro-1,4-benzodioxin-5-ylmethylamino)pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[[2-fluoro-4-(trifluoromethyl)phenyl]methylamino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[2-[(2-Chloro-6-fluoro-3-methylphenyl)methylamino]-4-cyclopropyliminopyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[2-[(2-Bromophenyl)methyl-methylamino]-4-cyclopropyliminopyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[[2-fluoro-5-(trifluoromethyl)phenyl]methylamino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[(3,5-dimethoxyphenyl)methylamino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[[3-fluoro-5-(trifluoromethyl)phenyl]methylamino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[1-(2,3-dihydro-1,4-benzodioxin-6-yl)propylamino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 5-[(E)-[7-Cyclopropylimino-5-(2-fluoropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-4-hydroxy-3H-1,3-thiazole-2-thione | IC50 | 1590.8 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[[3-fluoro-4-(trifluoromethyl)phenyl]methylamino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[(3-methylthiophen-2-yl)methylamino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 2-[[[(8E)-4-Cyclopropylimino-8-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino]methyl]benzonitrile | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[[(1S)-1-naphthalen-2-ylethyl]amino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[2-[(6-Chloro-2-fluoro-3-methylphenyl)methylamino]-4-cyclopropyliminopyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 5-[(E)-[7-Cyclopropylimino-5-(4-pyridin-2-ylpiperazin-1-yl)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-4-hydroxy-3H-1,3-thiazol-2-one | IC50 | 1820.0 [1] |
 | 2-[[(8E)-4-Cyclopropylimino-8-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino]-2-(2-fluorophenyl)acetic acid | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[[(1R)-1-(3-methoxyphenyl)ethyl]amino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[(2,5-dimethylfuran-3-yl)methylamino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[(3-hydroxyphenyl)methylamino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[(2-fluorophenyl)methyl-methylamino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[(3-methylsulfanylphenyl)methylamino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[(3-piperidin-1-ylphenyl)methylamino]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 3-[[(3E)-7-Cyclopropylimino-3-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a]pyrimidin-5-yl]methyl]benzonitrile | IC50 | 2500.0 [1] |
 | 4-[(E)-[7-Cyclopropylimino-5-(4,4-difluoropiperidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 359.0 [1] |
 | 4-[(E)-(4-Cyclopropylimino-2-methylsulfanylpyrazolo[1,5-a][1,3,5]triazin-8-ylidene)methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1306.4 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-[3-(piperazine-1-carbonyl)phenyl]iminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1234.8 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[5-(4-ethylpiperazine-1-carbonyl)benzimidazol-1-yl]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 3-[[(3E)-5-(3-Chloroanilino)-3-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a]pyrimidin-7-ylidene]amino]benzoic acid | IC50 | 2500.0 [1] |
 | 4-[(E)-(4-Cyclopropylimino-2-methylsulfonylpyrazolo[1,5-a][1,3,5]triazin-8-ylidene)methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 5-[(E)-[7-Cyclopropylimino-5-(2-hydroxypropylamino)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-4-hydroxy-3H-1,3-thiazol-2-one | IC50 | 2500.0 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-(1-ethylpiperidin-4-yl)iminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 4-[(E)-[5-(Cyclopentylamino)-7-cyclopropyliminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-(1-propan-2-ylpiperidin-4-yl)iminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[4-(pyrrolidin-1-ylmethyl)imidazol-1-yl]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-[2-(dimethylamino)ethylimino]pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 4-[(E)-[7-Cyclopropylimino-5-(3-methylsulfonylphenyl)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 5-[(E)-[7-Cyclopropylimino-5-(4-methyl-1,4-diazepan-1-yl)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-4-hydroxy-3H-1,3-thiazol-2-one | IC50 | 2046.1 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-[3-(trifluoromethoxy)phenyl]pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 4-[(E)-(7-Cyclopropylimino-5-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-3-ylidene)methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-[1-(2-hydroxypropyl)piperidin-4-yl]iminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 5-[(E)-[7-Cyclopropylimino-5-(diethylamino)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-4-hydroxy-3H-1,3-thiazol-2-one | IC50 | 1432.7 [1] |
 | 4-[(E)-[7-Benzylsulfinyl-5-(3-chlorophenyl)iminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 296.8 [1] |
 | 4-[[(8E)-4-Cyclopropylimino-8-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino]cyclohexane-1-carboxamide | IC50 | 2500.0 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-propan-2-yliminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-pyrrolidin-3-yliminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 700.8 [1] |
 | 4-[(E)-[7-Cyclopropylimino-5-(2-fluoropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | N-[(3E)-7-Cyclopropylimino-3-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a]pyrimidin-5-yl]cyclopropanecarboxamide | IC50 | 2500.0 [1] |
 | 4-[(E)-[7-Benzylsulfanyl-5-(3-chlorophenyl)iminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2244.9 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-piperidin-4-yliminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2449.1 [1] |
 | 3-[(3E)-7-Cyclopropylimino-3-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a]pyrimidin-5-yl]-N-methylbenzenesulfonamide | IC50 | 2500.0 [1] |
 | 3-[(3E)-7-Cyclopropylimino-3-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a]pyrimidin-5-yl]benzonitrile | IC50 | 2500.0 [1] |
 | 5-[(E)-[7-Cyclopropylimino-5-[methyl-(1-methylpyrrolidin-3-yl)amino]pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-4-hydroxy-3H-1,3-thiazol-2-one | IC50 | 1437.9 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-(2-hydroxypropylimino)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 316.5 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-[1-(cyclopropanecarbonyl)piperidin-4-yl]iminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-(2-morpholin-4-ylethylimino)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2190.5 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-[1-(2-hydroxyethyl)piperidin-4-yl]iminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 4-[(E)-[2-(3-Chloroanilino)-4-cyclopropyliminopyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 5-[(E)-[7-Cyclopropylimino-5-(dimethylamino)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-4-hydroxy-3H-1,3-thiazol-2-one | IC50 | 875.9 [1] |
 | Tert-butyl 4-[3-[[(3E)-5-(3-chloroanilino)-3-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a]pyrimidin-7-ylidene]amino]benzoyl]piperazine-1-carboxylate | IC50 | 2019.3 [1] |
 | N-[(3E)-7-Cyclopropylimino-3-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a]pyrimidin-5-yl]-2-fluorobenzamide | IC50 | 10818.0 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-[1-(2,2-dimethylpropanoyl)piperidin-4-yl]iminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 4-[(E)-[7-Cyclopropylimino-5-(3-fluorophenyl)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 4-[(E)-[7-Cyclopropylimino-5-(3-hydroxyphenyl)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 613.5 [1] |
 | Tert-butyl 3-[[(3E)-5-(3-chloroanilino)-3-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a]pyrimidin-7-ylidene]amino]benzoate | IC50 | 2500.0 [1] |
 | 4-[(E)-[7-Cyclopropylimino-5-[3-(trifluoromethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 890.8 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-(2-hydroxyethylimino)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 474.7 [1] |
 | N-[4-[[(3E)-7-Cyclopropylimino-3-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a]pyrimidin-5-yl]amino]cyclohexyl]propanamide | IC50 | 2500.0 [1] |
 | 5-[(E)-[7-Cyclopropylimino-5-(2-methylpropylamino)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-4-hydroxy-3H-1,3-thiazol-2-one | IC50 | 1643.8 [1] |
 | 4-[[(8E)-4-Cyclopropylimino-8-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino]-N-methylcyclohexane-1-carboxamide | IC50 | 2500.0 [1] |
 | 4-[(E)-[7-Cyclopropylimino-5-[3-(hydroxymethyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1249.7 [1] |
 | N-[[3-[(3E)-7-Cyclopropylimino-3-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a]pyrimidin-5-yl]phenyl]methyl]acetamide | IC50 | 1727.1 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-(pyridin-4-ylmethylimino)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1334.5 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-(cyclopropylmethylamino)pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 2500.0 [1] |
 | 4-[(E)-[5-(3-Chloroanilino)-7-(pyridin-2-ylmethylimino)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 421.1 [1] |
 | 4-[(E)-[7-Cyclopropylimino-5-(3,5-difluoroanilino)pyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1970.6 [1] |
 | Methyl 4-[[(3E)-5-(3-chloroanilino)-3-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a]pyrimidin-7-ylidene]amino]piperidine-1-carboxylate | IC50 | 2500.0 [1] |
 | 5-[(E)-[5-(3-Chloroanilino)-7-cyclopropyliminopyrazolo[1,5-a]pyrimidin-3-ylidene]methyl]-4-hydroxy-3H-1,3-thiazol-2-one | IC50 | 2500.0 [1] |
 | 4-[(E)-[4-Cyclopropylimino-2-(1-pyridin-2-ylethylamino)pyrazolo[1,5-a][1,3,5]triazin-8-ylidene]methyl]-5-hydroxy-1,3-dihydroimidazol-2-one | IC50 | 1000.0 [1] |
 | 5-[(3E)-7-Cyclopropylimino-3-[(5-hydroxy-2-oxo-1,3-dihydroimidazol-4-yl)methylidene]pyrazolo[1,5-a]pyrimidin-5-yl]-N-(3-methoxypropyl)thiophene-2-carboxamide | IC50 | 2500.0 [1] |
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