 | 1-Methyl-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1h-indole-2,3-dione | IC50 | 10000.0 [1] |
| 1-Methyl-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1h-indole-2,3-dione | Ki | 15.0 [1], 56.1 [2] |
 | Ac-DEVD-CHO | IC50 | 2.2 [1] |
 | Caspase-3/7 Inhibitor I | IC50 | 119.95 [1] |
| Caspase-3/7 Inhibitor I | Ki | 41.8 [1], 60.0 [2] |
 | (S)-5-(2-Phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 44.0 [1] |
| (S)-5-(2-Phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione | Ki | 8.3 [1], 15.0 [2] |
 | (S)-1-(4-(2-Fluoroethoxy)benzyl)-5-(2-(phenoxymethyl)pyrrolidin-1-ylsulfonyl)indoline-2,3-dione | IC50 | 0.3 [1], 6.1 [2], 9.7 [3], 9.77 [4] |
| (S)-1-(4-(2-Fluoroethoxy)benzyl)-5-(2-(phenoxymethyl)pyrrolidin-1-ylsulfonyl)indoline-2,3-dione | Ki | 0.2 [1] |
 | Isatin Sulfonamide 34 | IC50 | 2.5 [1], 12.2 [2], 12.3 [3], 14.5 [4] |
| Isatin Sulfonamide 34 | Ki | 1.2 [1] |
 | (S)-5-(2-(Methoxymethyl)pyrrolidin-1-ylsulfonyl)-1-methylindoline-2,3-dione | IC50 | 2.4 [1] |
| (S)-5-(2-(Methoxymethyl)pyrrolidin-1-ylsulfonyl)-1-methylindoline-2,3-dione | Ki | 1.2 [1] |
 | (S)-1-(4-Hydroxybenzyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 8.2 [1], 13.49 [2], 13.5 [3] |
| (S)-1-(4-Hydroxybenzyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione | Ki | 4.0 [1] |
 | (S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 9.7 [1], 14.45 [2], 14.5 [3] |
| (S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione | Ki | 4.8 [1] |
 | (3S)-5-Benzylsulfanyl-3-[[(2S)-2-[[2-(5-bromo-2-methoxyphenyl)acetyl]amino]-3-methylbutanoyl]amino]-4-oxopentanoic acid | IC50 | 17.7 [1], 18.0 [2], 60.0 [3] |
 | 5-(Pyrrolidin-1-ylsulfonyl)indoline-2,3-dione | IC50 | 2798.98 [1], 2800.0 [2] |
| 5-(Pyrrolidin-1-ylsulfonyl)indoline-2,3-dione | Ki | 1400.0 [1] |
 | 5-(2-((Methyl(phenyl)amino)methyl)pyrrolidin-1-ylsulfonyl)indoline-2,3-dione | IC50 | 5495.41 [1], 5500.0 [2] |
| 5-(2-((Methyl(phenyl)amino)methyl)pyrrolidin-1-ylsulfonyl)indoline-2,3-dione | Ki | 12000.0 [1] |
 | (2S)-N-[(3S)-2-Hydroxy-5-oxooxolan-3-yl]-4-methyl-2-[(2-naphthalen-2-yloxyacetyl)amino]pentanamide | IC50 | 940.0 [1], 944.0 [2] |
 | (S)-3-((S)-2-(Benzyloxycarbonylamino)-3-methylbutanamido)-5-(methylsulfonyl)pent-4-enoic acid | IC50 | 3330.0 [1], 35300.0 [2], 133400.0 [3] |
 | 5-[(2S)-2-(Methoxymethyl)pyrrolidin-1-yl]sulfonyl-1-[(4-methoxyphenyl)methyl]indole-2,3-dione | IC50 | 17.6 [1], 18.4 [2] |
| 5-[(2S)-2-(Methoxymethyl)pyrrolidin-1-yl]sulfonyl-1-[(4-methoxyphenyl)methyl]indole-2,3-dione | Ki | 9.0 [1] |
 | 1-[[4-(2-Fluoroethoxy)phenyl]methyl]-5-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione | IC50 | 8.3 [1], 36.4 [2] |
| 1-[[4-(2-Fluoroethoxy)phenyl]methyl]-5-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione | Ki | 17.9 [1] |
 | 1,2-Benzisothiazol-3(2H)-one | IC50 | 46740.0 [1] |
 | 3-((S)-2-(((Benzyloxy)carbonyl)amino)-3-methylbutanamido)-5-fluoro-4-oxopentanoic acid | IC50 | 30.0 [1] |
 | 1-[(4-Methoxyphenyl)methyl]-5-[(2S)-2-(pyridin-3-yloxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione | IC50 | 3.89 [1], 3.9 [2] |
 | 1-Methyl-5-nitroindoline-2,3-dione | IC50 | 1000.0 [1] |
| 1-Methyl-5-nitroindoline-2,3-dione | Ki | 500.0 [1] |
 | (S)-1-Benzyl-5-(2-phenoxymethyl-azetidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 9.7 [1], 9.77 [2] |
 | (S)-1-Methyl-5-(2-phenoxymethyl-azetidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 91.2 [1], 91.7 [2] |
 | 5-(2-(Pyridin-3-yl-oxymethyl)-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 58.3 [1], 58.88 [2] |
 | 1-Benzyl-5-(2-(pyridin-3-yl-oxymethyl)-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 5.2 [1], 5.25 [2] |
 | (S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 12.02 [1], 12.1 [2] |
 | (S)-5-(2-Phenoxymethyl-azetidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 286.7 [1], 288.4 [2] |
 | 1-Methyl-5-(2-(pyridin-3-yl-oxymethyl)-pyrrolidine-1-sulfonyl)--1H-indole-2,3-dione | IC50 | 23.3 [1], 23.44 [2] |
 | (S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-azetidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 8.32 [1], 8.4 [2] |
 | 5-[(2S)-2-[(2,4-Difluorophenoxy)methyl]pyrrolidin-1-yl]sulfonyl-1-[[1-(2-fluoroethyl)triazol-4-yl]methyl]indole-2,3-dione | IC50 | 0.5 [1], 10.8 [2] |
 | 1-[[1-(2-Fluoroethyl)triazol-4-yl]methyl]-5-[(2S)-2-(phenoxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione | IC50 | 12.2 [1], 16.7 [2] |
 | 5-(Piperidin-1-ylsulfonyl)-1H-indole-2,3-dione | IC50 | 2197.86 [1], 2200.0 [2] |
 | (2S)-N-[(3S)-2-Hydroxy-5-oxooxolan-3-yl]-4-methyl-2-[(2-naphthalen-1-yloxyacetyl)amino]pentanamide | IC50 | 135.0 [1] |
 | N-(2-Methoxyethyl)-N-methyl-2,3-dioxo-1H-indole-5-sulfonamide | IC50 | 909.91 [1], 910.0 [2] |
 | (S)-1-(4-Methylthiobenzyl)-5-(2-phenoxymethyl-azetidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 11.22 [1], 11.3 [2] |
 | 5-(2-(Pyridin-4-yl-oxymethyl)-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 20.4 [1], 20.42 [2] |
 | [4-[[2,3-Dioxo-5-[(2S)-2-(phenoxymethyl)pyrrolidin-1-yl]sulfonylindol-1-yl]methyl]phenyl] acetate | IC50 | 12.0 [1], 12.02 [2] |
 | (S)-1-(4-Methylthiobenzyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 12.3 [1], 12.4 [2] |
 | (S)-1-(6-Fluoropyridin-2-yl-methyl)-5-(2-phenoxymethylazetidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 5.75 [1], 5.8 [2] |
 | (s)-1-(6-Fluoropyridin-3-yl-methyl)-5-(2-phenoxymethylpyrrolidine-1-sulfonyl)-1h-indole-2,3-dione | IC50 | 10.23 [1], 10.3 [2] |
 | (S)-1-(4-Iodobenzyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)isatin | IC50 | 2.4 [1] |
| (S)-1-(4-Iodobenzyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)isatin | Ki | 1.2 [1] |
 | (S)-1-(2-Fluoropyridin-4-yl-methyl)-5-(2-phenoxymethylazetidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 29.2 [1], 29.51 [2] |
 | (S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-azetidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 8.71 [1], 8.8 [2] |
 | (S)-1-(2-Fluoro-pyridin-4-yl-methyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 21.3 [1], 21.38 [2] |
 | (S)-1-(6-Fluoropyridin-3-ylmethyl)-5-(2-phenoxymethylazetidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 10.9 [1], 10.96 [2] |
 | (S)-1-(2-Fluorobenzyl)-5-(2-phenoxymethyl-azetidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 9.33 [1], 9.4 [2] |
 | (S)-1-(6-Fluoro-pyridin-2-yl-methyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione | IC50 | 9.1 [1], 9.12 [2] |
 | 1-(4-Methylthiobenzyl)-5-(2-(pyridin-3-yl-oxymethyl)-pyrrolidine-1-sulfonyl)-1h-indole-2,3-dione | IC50 | 4.37 [1], 4.4 [2] |
 | 1-(4-Fluorobenzyl)-5-(2-(pyridin-3-yl-oxymethyl)-pyrrolidine-1-sulfonyl)-1h-indole-2,3-dione | IC50 | 8.32 [1], 8.4 [2] |
 | 1-[(4-Hydroxyphenyl)methyl]-5-[(2S)-2-(pyridin-3-yloxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione | IC50 | 3.89 [1], 3.9 [2] |
 | 1-[(4-Bromophenyl)methyl]-5-[(2S)-2-(phenoxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione | IC50 | 9.77 [1], 9.85 [2] |
 | 1-(4-Bromo-benzyl)-5-[2-(pyridin-3-yl-oxymethyl)-pyrrolidine-1-sulfonyl]-1H-indole-2,3-dione | IC50 | 3.6 [1], 3.63 [2] |
 | 2-[1-Benzyl-2-oxo-5-[(2S)-2-(phenoxymethyl)pyrrolidin-1-yl]sulfonylindol-3-ylidene]propanedinitrile | IC50 | 27.8 [1] |
 | Tert-butyl 1-[(2,3-dioxo-1H-indol-5-yl)sulfonyl]pyrrolidine-2-carboxylate | IC50 | 69.98 [1], 70.0 [2] |
 | Methyl 1-[(2,3-dioxo-1H-indol-5-yl)sulfonyl]pyrrolidine-2-carboxylate | IC50 | 169.82 [1], 170.0 [2] |
 | (3S)-5-Benzylsulfanyl-3-[[(2S)-3-methyl-2-[(2-phenylacetyl)amino]butanoyl]amino]-4-oxopentanoic acid | IC50 | 746.0 [1], 750.0 [2] |
 | (3S)-3-[[(2S)-2-[[2-(5-Acetyl-2-methoxyphenyl)acetyl]amino]-3-methylbutanoyl]amino]-5-benzylsulfanyl-4-oxopentanoic acid | IC50 | 10.0 [1], 13.0 [2] |
 | 1-[(3,4-Dichlorophenyl)methyl]-5-morpholin-4-ylsulfonylindole-2,3-dione | IC50 | 1430.0 [1], 1445.44 [2] |
 | 1-Benzyl-5-thiomorpholinosulfonyl Isatin | IC50 | 1023.29 [1], 1028.0 [2] |
 | 5-(Azetidin-1-ylsulfonyl)-1-benzylindole-2,3-dione | IC50 | 114.0 [1], 114.82 [2] |
 | 5-[(2S)-2-(Methoxymethyl)pyrrolidin-1-yl]sulfonyl-1-propylindole-2,3-dione | IC50 | 5.3 [1] |
 | 1-Butyl-5-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione | IC50 | 29.0 [1] |
 | 1-[(2,3-Dioxo-1H-indol-5-yl)sulfonyl]-N,N-dimethylpyrrolidine-2-carboxamide | IC50 | 410.0 [1], 410.2 [2] |
 | 5-[2-(Phenylsulfanylmethyl)pyrrolidin-1-yl]sulfonyl-1H-indole-2,3-dione | IC50 | 43.95 [1], 44.0 [2] |
 | Benzyl N-[(4S,7S,10aS)-4-[[(3S)-2-hydroxy-5-oxooxolan-3-yl]carbamoyl]-6-oxo-2,3,4,7,8,9,10,10a-octahydro-1H-pyrido[1,2-a]azepin-7-yl]carbamate | IC50 | 10000.0 [1] |
 | (3S)-3-Acetamido-4-[[(3R,6S,9aR)-3-[[(3S)-2-hydroxy-5-oxooxolan-3-yl]carbamoyl]-5-oxo-3,6,7,8,9,9a-hexahydro-2H-[1,3]thiazolo[3,2-a]azepin-6-yl]amino]-4-oxobutanoic acid | IC50 | 18.0 [1] |
 | (4S)-4-[[(2S)-2-Acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(3S)-2-hydroxy-5-oxooxolan-3-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid | IC50 | 1.2 [1], 3.5 [2] |
 | (4S)-5-[[(2S)-1-[[(3S)-2-Hydroxy-5-oxooxolan-3-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-oxo-4-(phenylmethoxycarbonylamino)pentanoic acid | IC50 | 2.3 [1] |
 | Benzyl N-[(3R)-1-[(3S)-2-hydroxy-5-oxooxolan-3-yl]-5-methyl-2-oxohexan-3-yl]carbamate | IC50 | 3470.0 [1] |
 | Benzyl N-[(3R)-1-[(3S)-2-hydroxy-5-oxooxolan-3-yl]-4-methyl-2-oxopentan-3-yl]carbamate | IC50 | 1750.0 [1] |
 | (3S)-3-[2-[5-Tert-butyl-3-[(4-methyl-1,2,5-oxadiazol-3-yl)methylamino]-2-oxopyrazin-1-yl]butanoylamino]-4-oxo-7-phenylheptanoic acid | IC50 | 0.01 [1], 14.0 [2] |
 | 1-Ethyl-5-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione | IC50 | 183.0 [1] |
 | 1-(4-Fluorobutyl)-5-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione | IC50 | 41.0 [1] |
 | (E,3S)-5-(Benzenesulfonyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)pent-4-enoic acid | IC50 | 16200.0 [1], 228000.0 [2] |
 | (E,3S)-3-(9H-Fluoren-9-ylmethoxycarbonylamino)-5-methylsulfonylpent-4-enoic acid | IC50 | 23700.0 [1], 163200.0 [2] |
 | (E,3S)-5-(Benzenesulfonyl)-3-[[(2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]pent-4-enoic acid | IC50 | 28300.0 [1], 185400.0 [2] |
 | (E,3S)-3-[[(2S,3S)-3-Methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-5-methylsulfonylpent-4-enoic acid | IC50 | 30500.0 [1], 94600.0 [2] |
 | (E,3S)-5-(Benzenesulfonyl)-3-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoyl]amino]pent-4-enoic acid | IC50 | 29900.0 [1], 69100.0 [2] |
 | (E,3S)-3-[[(2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoyl]amino]-5-methylsulfonylpent-4-enoic acid | IC50 | 28800.0 [1], 34000.0 [2] |
 | 1-[(3-Benzyltriazol-4-yl)methyl]-5-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione | IC50 | 9.0 [1] |
| 1-[(3-Benzyltriazol-4-yl)methyl]-5-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione | Ki | 10.5 [1] |
 | 1-[[1-(2,3-Dihydro-1,4-benzodioxin-6-yl)triazol-4-yl]methyl]-5-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione | IC50 | 17.0 [1] |
| 1-[[1-(2,3-Dihydro-1,4-benzodioxin-6-yl)triazol-4-yl]methyl]-5-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione | Ki | 14.5 [1] |
 | (3S)-5-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-3-[[(2S)-2-[[2-[2-ethoxy-5-[(E)-3-methoxy-3-oxoprop-1-enyl]phenyl]acetyl]amino]-3-methylbutanoyl]amino]-4-oxopentanoic acid | IC50 | 7.95 [1], 8.0 [2] |
 | N-(4-Morpholin-4-ylphenyl)-3-oxo-1,2-benzothiazole-2-carboxamide | IC50 | 1.15 [1], 106.3 [2] |
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