 | [5-Amino-1-(benzenesulfonyl)pyrazol-3-yl] thiophene-2-carboxylate | IC50 | 1800.0 [1] |
 | Leupeptin | IC50 | 9.4 [1], 47.0 [2], 117.0 [3] |
| Leupeptin | Ki | 5.0 [1], 7.0 [2] |
 | Nitroxoline | Ki | 154400.0 [1] |
 | Balicatib | IC50 | 61.0 [1], 4750.0 [2], 4800.0 [3] |
| Balicatib | Ki | 2900.0 [1], 3800.0 [2] |
 | (2R)-N-(Cyanomethyl)-4-methyl-2-[3-(4-piperazin-1-ylphenyl)phenyl]pentanamide | IC50 | 3950.0 [1], 4400.0 [2], 86000.0 [3] |
| (2R)-N-(Cyanomethyl)-4-methyl-2-[3-(4-piperazin-1-ylphenyl)phenyl]pentanamide | Ki | 3843.0 [1] |
 | e-64 | IC50 | 5.0 [1], 10.0 [2], 16.0 [3], 40.0 [4] |
| e-64 | Ki | 16000.0 [1] |
 | L-873724 | IC50 | 4807.0 [1], 5239.0 [2] |
 | 2-Methyl-5-nitroquinoline-8-ol | Ki | 77000.0 [1], 99000.0 [2], 153000.0 [3], 181000.0 [4], 469000.0 [5] |
 | N-Benzyl-N-(cyanomethyl)-8-hydroxy-5-nitroquinoline-7-carboxamide | Ki | 32000.0 [1], 64000.0 [2], 132000.0 [3], 182000.0 [4], 185000.0 [5] |
 | N-(Cyanomethyl)-8-hydroxy-5,7-dinitroquinoline-2-carboxamide | Ki | 29000.0 [1], 34000.0 [2], 160000.0 [3], 201000.0 [4] |
 | 8-Hydroxy-5-nitroquinoline-2-carbonitrile | Ki | 68000.0 [1], 123000.0 [2], 142000.0 [3], 214000.0 [4] |
 | CID 11199915 | IC50 | 100.0 [1], 1360.0 [2] |
| CID 11199915 | Ki | 18.0 [1], 25.0 [2] |
 | N-(1-((Cyanomethyl)carbamoyl)cyclohexyl)-4-(2-(4-methylpiperazin-1-yl)thiazol-4-yl)benzamide | IC50 | 17.0 [1], 1050.0 [2], 1100.0 [3] |
| N-(1-((Cyanomethyl)carbamoyl)cyclohexyl)-4-(2-(4-methylpiperazin-1-yl)thiazol-4-yl)benzamide | Ki | 1000.0 [1] |
 | N-[[1-(1,3-Benzothiazol-2-ylmethyl)piperidin-4-yl]methyl]-8-hydroxy-N-(2-methoxyethyl)-5-nitroquinoline-7-carboxamide | Ki | 41000.0 [1], 181000.0 [2], 200000.0 [3] |
 | 2-(Morpholin-4-ylmethyl)-4-nitrophenol | Ki | 97000.0 [1], 212000.0 [2] |
 | (2-Hydroxy-5-nitrophenyl)(morpholino)methanone | Ki | 176000.0 [1], 237000.0 [2] |
 | 8-Hydroxy-5-nitroquinoline-2-carboxylic acid | Ki | 139000.0 [1], 240000.0 [2] |
 | N-(Cyanomethyl)-5-nitroquinoline-8-carboxamide | Ki | 190000.0 [1], 240000.0 [2], 294000.0 [3] |
 | N-(Cyanomethyl)-8-hydroxy-N-methyl-5-nitroquinoline-2-carboxamide | Ki | 102000.0 [1], 205000.0 [2], 263000.0 [3] |
 | N-(Cyanomethyl)-2-hydroxy-5-nitrobenzamide | Ki | 168000.0 [1], 271000.0 [2] |
 | 8-(1-Methylpyrrol-2-yl)-5-nitroquinoline | Ki | 224000.0 [1], 333000.0 [2] |
 | (8-Hydroxy-5-nitroquinolin-7-yl)-piperidin-1-ylmethanone | Ki | 171000.0 [1], 311000.0 [2], 364000.0 [3] |
 | N-[[1-(1,3-Benzothiazol-2-yl)piperidin-4-yl]methyl]-8-hydroxy-5-nitroquinoline-7-carboxamide | Ki | 12000.0 [1], 18000.0 [2], 322000.0 [3] |
 | N-Benzyl-N-(cyanomethyl)-8-hydroxy-5,7-dinitroquinoline-2-carboxamide | Ki | 9000.0 [1], 35000.0 [2], 154000.0 [3], 163000.0 [4] |
 | N-(Cyanomethyl)-8-hydroxy-N-methyl-5,7-dinitroquinoline-2-carboxamide | Ki | 109000.0 [1], 122000.0 [2], 257000.0 [3], 341000.0 [4] |
 | N-Benzyl-N-(cyanomethyl)-2-hydroxy-5-nitrobenzamide | Ki | 96000.0 [1], 342000.0 [2] |
 | N-(Cyanomethyl)-8-hydroxy-5-nitroquinoline-2-carboxamide | Ki | 116000.0 [1], 180000.0 [2], 190000.0 [3] |
 | 8-[4-Methoxy-3-(3-methoxypropoxy)phenyl]-5-nitroquinoline | Ki | 22000.0 [1], 118000.0 [2], 323000.0 [3] |
 | N-(Cyanomethyl)-8-hydroxy-N-methyl-5-nitroquinoline-7-carboxamide | Ki | 121000.0 [1], 185000.0 [2] |
 | (8-Hydroxy-5-nitroquinolin-7-yl)-(4-methylpiperidin-1-yl)methanone | Ki | 94000.0 [1], 143000.0 [2], 162000.0 [3] |
 | N-(1-Cyanocyclopropyl)-8-hydroxy-5-nitroquinoline-2-carboxamide | Ki | 66000.0 [1], 154000.0 [2], 157000.0 [3] |
 | N-(Cyanomethyl)-8-hydroxy-5-nitroquinoline-7-carboxamide | Ki | 30000.0 [1], 67000.0 [2], 128000.0 [3], 206000.0 [4] |
 | 2-Amino-5-nitroquinolin-8-ol | Ki | 202000.0 [1], 329000.0 [2] |
 | (8-Hydroxy-5-nitroquinolin-7-yl)-morpholin-4-ylmethanone | Ki | 122000.0 [1], 136000.0 [2] |
 | N-[[1-(1,3-Benzoxazol-2-yl)piperidin-4-yl]methyl]-8-hydroxy-5-nitroquinoline-7-carboxamide | Ki | 8000.0 [1], 8200.0 [2], 13000.0 [3], 237000.0 [4] |
 | N,N-Diethyl-1-(5-nitroquinolin-8-yl)piperidine-3-carboxamide | Ki | 36000.0 [1], 105000.0 [2], 117000.0 [3], 155000.0 [4] |
 | Telaprevir | IC50 | 210.0 [1], 2300.0 [2], 4400.0 [3] |
 | Morpholine-4-carboxylic acid (1-(3-benzenesulfonyl-1-phenethylallylcarbamoyl)-3-methylbutyl)-amide | IC50 | 3.0 [1], 1360.0 [2], 4504.0 [3] |
 | 4-Nitro-1-naphthylamine | Ki | 111000.0 [1], 147000.0 [2], 217000.0 [3] |
 | Benzyl N-[(2S)-4-methyl-1-[3-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-4-oxopyrrolidin-1-yl]-1-oxopentan-2-yl]carbamate | Ki | 1000.0 [1] |
 | (2S)-N-(Cyanomethyl)-4-methyl-2-[[(1S)-2,2,2-trifluoro-1-[4-(4-piperazin-1-ylphenyl)phenyl]ethyl]amino]pentanamide | IC50 | 82.0 [1], 1111.0 [2] |
 | Pyrrolidine, 1-(4-nitro-1-naphthalenyl)- | Ki | 34000.0 [1], 170000.0 [2], 277000.0 [3] |
 | N-[(2S)-4-Methyl-1-oxo-1-[[(4S)-3-oxo-1-pyridin-2-ylsulfonylazepan-4-yl]amino]pentan-2-yl]-1-benzofuran-2-carboxamide | Ki | 500.0 [1] |
 | N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-(2-morpholin-4-yl-1,3-thiazol-4-yl)benzamide | IC50 | 2900.0 [1], 4200.0 [2] |
| N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-(2-morpholin-4-yl-1,3-thiazol-4-yl)benzamide | Ki | 3100.0 [1] |
 | N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-morpholin-4-ylbenzamide | IC50 | 4400.0 [1], 15400.0 [2] |
| N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-morpholin-4-ylbenzamide | Ki | 8600.0 [1] |
 | N-[(2S)-3-(3-Bromophenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl]-4-phenylbenzamide | Ki | 120.0 [1], 205.0 [2], 220.0 [3] |
 | Methyl 2-[4-[[(2R)-2-[[(2S)-3-(3-bromophenyl)-2-[(4-phenylbenzoyl)amino]propanoyl]amino]-2-cyanoethoxy]methyl]triazol-1-yl]acetate | Ki | 26.0 [1], 131.0 [2], 136.0 [3] |
 | 2-[4-[[(2R)-2-[[(2S)-3-(3-Bromophenyl)-2-[(4-phenylbenzoyl)amino]propanoyl]amino]-2-cyanoethoxy]methyl]triazol-1-yl]acetic acid | Ki | 19.2 [1], 27.3 [2], 41.3 [3] |
 | 3-[4-[[(2R)-2-[[(2S)-3-(3-Bromophenyl)-2-[(4-phenylbenzoyl)amino]propanoyl]amino]-2-cyanoethoxy]methyl]triazol-1-yl]propanoic acid | Ki | 132.0 [1], 420.0 [2], 3640.0 [3] |
 | 2-[4-[(2S)-2-[[(2S)-3-(3-Bromophenyl)-2-[(4-phenylbenzoyl)amino]propanoyl]amino]-2-cyanoethyl]triazol-1-yl]acetic acid | Ki | 368.0 [1], 707.0 [2], 11200.0 [3] |
 | 8-Hydroxy-5,7-dinitroquinoline-2-carbonitrile | Ki | 39000.0 [1], 192000.0 [2] |
 | N-(1-Cyanocyclopropyl)-2-hydroxy-5-nitrobenzamide | Ki | 128000.0 [1], 247000.0 [2] |
 | N-(1-Cyanocyclopropyl)-8-hydroxy-5-nitroquinoline-7-carboxamide | Ki | 124000.0 [1], 185000.0 [2] |
 | N-Benzyl-N-(cyanomethyl)-8-hydroxy-5-nitroquinoline-2-carboxamide | Ki | 18000.0 [1], 34000.0 [2], 156000.0 [3] |
 | 8-(Morpholin-4-yl)-5-nitroquinoline | Ki | 153000.0 [1], 155000.0 [2], 180000.0 [3] |
 | N-Benzyl-5-nitroquinolin-8-amine | Ki | 127000.0 [1], 349000.0 [2], 364000.0 [3] |
 | N-Benzyl-N-methyl-5-nitroquinolin-8-amine | Ki | 137000.0 [1], 196000.0 [2], 242000.0 [3] |
 | 1-(5-Nitroquinoline-8-yl)piperidine-4-carboxylic acid ethyl ester | Ki | 38000.0 [1], 113000.0 [2], 162000.0 [3] |
 | 5-Nitro-N-(pyridin-2-ylmethyl)quinolin-8-amine | Ki | 47000.0 [1], 87000.0 [2], 107000.0 [3] |
 | 4-(4-Nitronaphthalen-1-yl)morpholine | Ki | 85000.0 [1], 125000.0 [2], 289000.0 [3] |
 | 7-[(Benzylamino)methyl]-5-nitroquinolin-8-ol | Ki | 58000.0 [1], 154000.0 [2], 198000.0 [3] |
 | 7-(Ethylaminomethyl)-5-nitroquinolin-8-ol | Ki | 82000.0 [1], 117000.0 [2], 136000.0 [3] |
 | 2-[Benzyl-[(8-hydroxy-5-nitroquinolin-7-yl)methyl]amino]acetonitrile | Ki | 8000.0 [1], 19000.0 [2], 79000.0 [3] |
 | 2-[(8-Hydroxy-5-nitroquinolin-7-yl)methyl-methylamino]acetonitrile | Ki | 76000.0 [1], 126000.0 [2], 172000.0 [3] |
 | 7-[[(2R)-2-Methylpiperidin-1-yl]methyl]-5-nitroquinolin-8-ol | Ki | 116000.0 [1], 203000.0 [2], 243000.0 [3] |
 | Ethyl 4-[(8-hydroxy-5-nitroquinolin-7-yl)methyl]piperazine-1-carboxylate | Ki | 87000.0 [1], 129000.0 [2], 156000.0 [3] |
 | Ethyl (1R,2S)-2-[(8-hydroxy-5-nitroquinolin-7-yl)methylamino]cyclohexane-1-carboxylate | Ki | 74000.0 [1], 130000.0 [2], 132000.0 [3] |
 | (1R,2S)-2-[(8-Hydroxy-5-nitroquinolin-7-yl)methylamino]cyclohexane-1-carboxylic acid | Ki | 125000.0 [1], 181000.0 [2], 250000.0 [3] |
 | 5-Nitro-7-[[4-(pyridin-3-ylmethyl)piperazin-1-yl]methyl]quinolin-8-ol | Ki | 171000.0 [1], 311000.0 [2], 364000.0 [3] |
 | 5-Nitro-7-[[4-(pyridin-4-ylmethyl)piperazin-1-yl]methyl]quinolin-8-ol | Ki | 94000.0 [1], 143000.0 [2], 162000.0 [3] |
 | 5-Nitro-8-(4-methylpiperidino)quinoline | Ki | 24000.0 [1], 105000.0 [2], 207000.0 [3] |
 | Z-Leu-leu-leu-al | Ki | 12.0 [1], 230.0 [2] |
 | Boceprevir | IC50 | 3300.0 [1], 6200.0 [2] |
 | Odanacatib | IC50 | 1034.0 [1], 1050.0 [2] |
 | Relacatib | IC50 | 14.0 [1] |
| Relacatib | Ki | 13.0 [1] |
 | Gallinamide A | IC50 | 1700.0 [1], 4200.0 [2] |
 | Pyrrolidine-1-carbonitrile | IC50 | 15000.0 [1], 25118.86 [2] |
 | 5,7-Dinitroquinolin-8-ol | Ki | 72000.0 [1], 146000.0 [2] |
 | Benzyl (S)-1-cyanomethylcarbamoyl-3-methylbutylcarbamate | Ki | 32000.0 [1], 123000.0 [2] |
 | Benzyl N-[(2S)-1-(cyanomethylamino)-1-oxo-3-phenylpropan-2-yl]carbamate | IC50 | 62000.0 [1] |
| Benzyl N-[(2S)-1-(cyanomethylamino)-1-oxo-3-phenylpropan-2-yl]carbamate | Ki | 330.0 [1] |
 | CID 44572423 | Ki | 7300.0 [1] |
 | Cathepsin inhibitor 1 | IC50 | 6309.57 [1] |
 | 1,3-Bis[[n-[(phenylmethoxy)carbonyl]-l-leucyl]amino]-2-propanone | Ki | 1300.0 [1] |
 | [(2S)-3,3-Dimethyl-1-[3-[4-(trifluoromethyl)phenyl]pyrazol-1-yl]butan-2-yl] N-[(3S)-1,2-dioxo-1-(1H-pyrazol-5-ylamino)heptan-3-yl]carbamate | IC50 | 20.0 [1], 20000.0 [2] |
 | N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-(4-piperazin-1-ylphenyl)benzamide | IC50 | 614.0 [1] |
| N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-(4-piperazin-1-ylphenyl)benzamide | Ki | 420.0 [1] |
 | Benzyl 1-((cyanomethyl)carbamoyl)cyclohexylcarbamate | Ki | 330.0 [1], 64000.0 [2] |
 | (S)-2-Amino-N-((S)-2-biphenyl-4-yl-1-cyano-ethyl)-butyramide | IC50 | 10000.0 [1] |
| (S)-2-Amino-N-((S)-2-biphenyl-4-yl-1-cyano-ethyl)-butyramide | Ki | 10.0 [1] |
 | (2S)-N-[(1S)-1-Cyano-2-phenylethyl]-4-methyl-2-[[(1S)-2,2,2-trifluoro-1-[4-(4-methylsulfonylphenyl)phenyl]ethyl]amino]pentanamide | IC50 | 163.0 [1], 953.0 [2] |
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