CD nomenclature rules.
Designation ▲ ▼ | Placement ▲ ▼ | Definition ▲ ▼ | Example ▲ ▼ |
Arbitrary number | Follows CD designation | Assigned to a molecule recognized by two or more mAbs. The number designates both the group of mAbs recognizing the cell surface molecule as well as the molecule itself. | CD4 |
Lowercase "w" | Precedes arbitrary number designation | Assigned to an insufficiently characterized molecule or ones only recognized by a single mAb. (W = Workshop) | CDw15 |
Lowercase letter | Follows arbitrary number designation | Assigned to molecules that share a commonality such as a common chain or the same gene family. | CD1a-CD1e share a common chain; CD66a-CD66f same gene family |
Uppercase letter | Follows arbitrary number designation | Indicates a spliced variant of the extracellular domain of a cell surface molecule. | CD45RA or CD45RO |
Superscript "+/-" | Follows arbitrary number designation | Indicates the presence or absence of that molecule on a cell or cell population. | CD4+CD8- |
Superscript "high/low" | Follows arbitrary number or uppercase letter designation | Indicates either a low or high expression level of a CD molecule by a cell subset. | CD4+CD45RAlowCD45ROhigh |
References
This online tool may be cited as follows
MLA | "Quest Database™ CD nomenclature rules.." AAT Bioquest, Inc., 19 May. 2025, https://www.aatbio.com/data-sets/cd-nomenclature-rules. | |
APA | AAT Bioquest, Inc. (2025, May 19). Quest Database™ CD nomenclature rules.. AAT Bioquest. https://www.aatbio.com/data-sets/cd-nomenclature-rules. | |
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