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CD nomenclature rules.

Designation
Placement
Definition
Example
Arbitrary numberFollows CD designationAssigned to a molecule recognized by two or more mAbs. The number designates both the group of mAbs recognizing the cell surface molecule as well as the molecule itself.CD4
Lowercase "w"Precedes arbitrary number designationAssigned to an insufficiently characterized molecule or ones only recognized by a single mAb. (W = Workshop)CDw15
Lowercase letterFollows arbitrary number designationAssigned to molecules that share a commonality such as a common chain or the same gene family.CD1a-CD1e share a common chain; CD66a-CD66f same gene family
Uppercase letterFollows arbitrary number designationIndicates a spliced variant of the extracellular domain of a cell surface molecule.CD45RA or CD45RO
Superscript "+/-"Follows arbitrary number designationIndicates the presence or absence of that molecule on a cell or cell population.CD4+CD8-
Superscript "high/low"Follows arbitrary number or uppercase letter designationIndicates either a low or high expression level of a CD molecule by a cell subset.CD4+CD45RAlowCD45ROhigh



References

This online tool may be cited as follows

MLA

"Quest Database™ CD nomenclature rules.." AAT Bioquest, Inc.19 May2025https://www.aatbio.com/data-sets/cd-nomenclature-rules.

APA

AAT Bioquest, Inc. (2025May 19). Quest Database™ CD nomenclature rules.. AAT Bioquest. https://www.aatbio.com/data-sets/cd-nomenclature-rules.
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