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AAT Bioquest

CD4 At A Glance

Specification
Value
SynonymsLeu-3, T4, OKT4
Cellular localizationCell membrane
Cellular ExpressionT cells, double positive thymocytes (e.g. CD4+CD8+), γ/δ T cells, innate lymphoid cells, macrophages, monocytes
Receptor TypeType 1 transmembrane glycoprotein, member of IgG superfamily
LigandAffinity for peptide-MHC Class II molecules, Interleukin-16 (IL-16), HIVgp120
FunctionMHC Class II molecule co-receptor, HIV receptor
Associated Signaling PathwaysT cell differentiation and T cell signal transduction pathways



References

This online tool may be cited as follows

MLA

"Quest Database™ CD4 At A Glance." AAT Bioquest, Inc.18 Jun2025https://www.aatbio.com/data-sets/cd4-at-a-glance.

APA

AAT Bioquest, Inc. (2025June 18). Quest Database™ CD4 At A Glance. AAT Bioquest. https://www.aatbio.com/data-sets/cd4-at-a-glance.
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